Research Profile Prof. Dr. Werner Kühlbrandt

Werner Kühlbrandt
  • Born 7 December 1951 in Bayreuth, Germany
  • Diploma (Chemistry), Free University Berlin. 1977
  • PhD (Molecular Biology), MRC Laboratory of Molecular Biology, Cambridge, UK, 1981
  • Group Leader and Senior Scientist, EMBL Heidelberg (1987-1997)
  • Director and Scientific Member, MPI of Biophysics, Frankfurt (since 1997)
  • Apl. Professor at Goethe Universität Frankfurt (since 1999)
  • Member of EMBO (1992), German National Academy of Science Leopoldina (2003)

Werner Kühlbrandt - Publications

A - Research papers:

Bausewein, T., Mills, D. J., Langer, J. D., Nitschke, B., Nussberger, S., and Kühlbrandt, W.: Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.
Cell 170 (4) 693-70 (2017).

Brandt, T., Mourier, A., Tain, L. S., Partridge, L., Larsson, N.-G., and Kühlbrandt, W.: Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila.
eLife Epub ahead of print, doi: 10.7554/eLife.24662 (2017).

Daum, B., Vonck, J., Bellack, A., Chaudhuri, P., Reichelt, R., Albers, S.-V., Rachel, R., and Kühlbrandt, W.: Structure and in situ organisation of the of Pyrococcus furiosus archaellum machinery.
eLife 21 pp., online, doi: 10.7554/eLife.27470 (2017).

Mühleip, A. W., Dewar, C. E., Schnaufer, A., Kühlbrandt, W., and Davies, K. M.: In situ structure of trypanosomal ATP synthase dimer reveals a unique arrangement of catalytic subunits.
Proc. Natl. Acad. Sci. USA 114 (5) 992-997 (2017).

Scherr, J., Parey, K., Klusch, N., Murphy, B. J., Balser, S., Neuhaus, A., Zickermann, V., Kühlbrandt, W., Terfort, A., and Rhinow, D.: Self-Perforated Hydrogel Nanomembranes Facilitate Structural Analysis of Proteins by Electron Cryo-Microscopy.
ACS Nano 11 (6) 6467-6473 (2017).

Schulz, S., Wilkes, M., Mills, D. J., Kühlbrandt, W., and Meier, T.: Molecular architecture of the N‐type ATPase rotor ring from Burkholderia pseudomallei.
EMBO Rep. 18 (6) online, pp. 526-535; doi: 10.15252/embr.201643374 (2017).

van Pee, K., Neuhaus, A., D'Imprima, E., Mills, D. J., Kühlbrandt, W., and Yildiz, Ö.: CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.
eLife 22 pp., online, doi: 10.7554/eLife.23644 (2017).

Wilkes, M., Madej, M. G., Kreuter, L., Rhinow, D., Heinz, V., De Sanctis, S., Ruppel, S., Richter, R. M., Joos, F., Grieben, M., Pike, A. C. W., Huiskonen, J. T., Carpenter, E. P., Kühlbrandt, W., Witzgall, R., and Ziegler, C.: Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2.
Nat. Struct. Mol. Biol. 24 (2) 123-130 (2017).

Brandt, T., Cavellini, L., Kühlbrandt, W., and Cohen, M.M.: A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro.
eLife 23 pp., online, doi: 10.7554/eLife.14618 (2016).

Călinescu, O., Linder, M., Wöhlert, D., Yildiz, Ö., Kühlbrandt, W., and Fendler, K.: Electrogenic Cation Binding in the Electroneutral Na+/H+ Antiporter of Pyrococcus abyssi.
J. Biol. Chem.
291 (52) 26786-26793 (2016).

Daum, B., Auerswald, A., Gruber, T., Hause, G., Balbach, J., Kühlbrandt, W., and Meister, A.: Supramolecular organization of the human N-BAR domain in shaping the sarcolemma membrane.J. Str. Biol. 194 (3) 375-382 (2016).

D'Imprima, E., Mills, D. J., Parey, K., Brandt, U., Kühlbrandt, W., Zickermann, V., and Vonck, J.: CryoEM structure of respiratory complex I reveals a link to mitochondrial sulfur metabolism.
BBA-Bioenergetics 1857 (12) 1935-1942 (2016).

Hahn, A., Parey, K., Bublitz, M., Mills, D. J., Zickermann, V., Vonck, J., Kühlbrandt, W., and Meier, T.: Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology.
Mol. Cell 63 (3) 445-456 (2016).

Mühleip, A. W., Joos, F., Wigge, C., Frangakis, A. S., Kühlbrandt, W., and Davies, K.: Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria.
Proc. Natl. Acad. Sci. USA 113 (30) 8442-8447 (2016).

Parey, K., Bublitz, M., Hahn, A., Zickermann, V., Kühlbrandt, W., and Meier, T.: Crystal structure of the yeast Yarrowia lipolytica F1c10 subcomplex in a late post-hydrolysis state.
BBA-Bioenergetics 1857 Suppl. e58 (abstract) 1 p. (2016).

Sousa, J. S., Mills, D. J., Vonck, J., and Kühlbrandt, W.: Functional asymmetry and electron flow in the bovine respirasome.
eLife 17 pp., online, doi: 10.7554/eLife.21290 (2016).

Allegretti, M., Klusch, N., Mills, D. J., Vonck, J., Kühlbrandt, W., and Davies, K. M.: Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase.
Nature 521 237-240 (2015).

Bohnert, M., Zerbes, R. M., Davies, K. M., Mühleip, A. W., Rampelt, H., Horvath, S. E., Boehnke, T., Kram, A., Perschil, I., Veenhuis, M., Kühlbrandt, W., van der Klei, I. J., Pfanner, N., and van der Laan, M.: Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System.
Cell Metab. 21 (5) 747-755 (2015).

Gold, V. A. M., Salzer, R., Averhoff, B., and Kühlbrandt, W.: Structure of a type IV pilus machinery in the open and closed state.
eLife 12 pp., online, doi: 10.7554/eLife.07380 (2015).

Hahn, A., Parey, K., Bublitz, M., Mills, D. J., Zickermann, V., Vonck, J., Kühlbrandt, W., and Meier, T.: Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology.
Mol. Cell 63 12 pp., in press, doi: 10.1016/j.molcel.2016.05.037 (2016).

Jiko, C., Davies, K. M., Shinzawa-Itoh, K., Tani, K., Maeda, S., Mills, D. J., Tsukihara, T., Fujiyoshi, Y., Kühlbrandt, W., and Gerle, C.: Bovine F1Fo ATP synthase monomers bend the lipid bilayer in 2D membrane crystals.
eLife 18 pp., online, doi: 10.7554/eLife.06119 (2015).

Kukat, C., Davies, K. M., Wurm, C. A., Spåhr, H., Bonekamp, N. A., Kühl, I., Joos, F., Polosa, P. L., Park, C. B., Posse, V., Falkenberg, M., Jakobs, S., Kühlbrandt, W., and Larsson, N.-G.: Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Proc. Natl. Acad. Sci. USA 112 (36) 11288-11293 (2015).

Müller, M., Bamann, C., Bamberg, E., and Kühlbrandt, W.: Light-Induced Helix Movements in Channelrhodopsin-2.
J. Mol. Biol. 427 (2) 341-349 (2015).

Vrandecic, K., Rätsep, M., Wilk, L., Rusevich, L., Golub, M., Reppert, M., Irrgang, K.-D., Kühlbrandt, W., and Pieper, J.: Protein Dynamics Tunes Excited State Positions in Light-Harvesting Complex I.
J. Phys. Chem. B 119 (10) 3920-3930 (2015).

Walter, A., Steltenkamp, S., Schmitz, S., Holik, P., Pakanavicius, E., Sachser, R., Huth, M., Rhinow, D., and Kühlbrandt, W.: Towards an optimum design for electrostatic phase plates.
Ultramicroscopy 153 22-31 (2015).

Wöhlert, D., Grötzinger, M. J., Kühlbrandt, W., and Yildiz, Ö.: Mechanism of Na+-dependent citrate transport from the structure of an asymmetrical CitS dimer.
eLife 18 pp., doi: 10.7554/eLife.09375 (2015).

Allegretti, M., Mills, D. J., McMullan, G., Kühlbrandt, W., and Vonck, J.: Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector.
eLife 20 pp.,  3:e01963; 20 pp. (2014).

Călinescu, O., Paulino, C., Kühlbrandt, W., and Fendler, K.: Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+.
J. Biol. Chem. 289 13168-13176 (2014).

Daum, B., Quax, T. E. F., Sachse, M., Mills, D. J., Reimann, J., Yildiz, Ö., Häder, S., Saveanu, C., Forterre, P., Albers, S.-V., and Kühlbrandt, W.: Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids.
Proc. Natl. Acad. Sci. USA 111 (10) 3829-3834 (2014).

Davies, K. M., Daum, B., Gold, V., Mühleip, A. W., Brandt, T., Blum, T., Mills, D. J., and Kühlbrandt, W.: Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography.
JoVE - Iss. No. 91, doi: 10.3791/512280; Sequ. No. of Article: e51228 (2014).

Gold, V. A. M., Ieva, R., Walter, A., Pfanner, N., van der Laan, M., and Kühlbrandt, W.: Visualizing active membrane protein complexes by electron cryotomography.
Nat. Commun. 5 Sequ. No. of Article: 4129 (2014).

Köster, S., van Pee, K., Hudel, M., Leustik, M., Rhinow, D., Kühlbrandt, W., Chakraborty, T., and Yildiz, Ö.: Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation.
Nat. Commun. 5 Sequ. No. of Article:3690, doi: 10.1038/ncomms4690 pp. 14 (2014).

Mourier, A., Ruzzenente, B., Brandt, T., Kühlbrandt, W., and Larsson, N.-G.: Loss of LRPPRC causes ATP synthase deficiency.
Hum. Mol. Genet. 23 (10) 2580-2592 (2014).

Patwardhan, A., Ashton, A., Brandt, R., Butcher, S., Carzaniga, R., Chiu, W., Collinson, L., Doux, P., Duke, E., Ellisman, M. H., Franken, E., Grünewald, K., Heriche, J.-K., Koster, A., Kühlbrandt, W., Lagerstedt, I., Larabell, C., Lawson, C. L., Saibil, H. R., Sanz-García, E., Subramaniam, S., Verkade, P., Swedlow, J. R., and Kleywegt, G. J.: A 3D cellular context for the macromolecular world.
Nat. Struct. Mol. Biol. 21 (10) 841-845 (2014).

Paulino, C. and Kühlbrandt, W.: pH- and sodium-induced changes in a sodium/proton antiporter.
eLife 17 pp., 3:e01412 (2014).

Paulino, C., Wöhlert, D., Kapotova, E., Yildiz, Ö., and Kühlbrandt, W.: Structure and transport mechanism of the sodium/proton antiporter MjNhaP1.
eLife; 3:e03583 (2014).

Wöhlert, D., Kühlbrandt, W., and Yildiz, Ö.: Structure and substrate ion binding in the sodium/proton antiporter PaNhaP.
eLife;  10.7554/eLife.03579 (2014).

Daum, B., Walter, A., Horst, A., Osiewacz, H. D., and Kühlbrandt, W.: Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria.
Proc. Natl. Acad. Sci. USA 110 (38) 15301-15306 (2013).

Kalayil, S., Schulze, S., and Kühlbrandt, W.: Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT.
Proc. Natl. Acad. Sci. USA 110 (43) 17296-17301 (2013).

Wilk, L., Grunwald, M., Liao, P.-N., Walla, P. J., and Kühlbrandt, W.: Direct interaction of the major light-harvesting complex II and PsbS in nonphotochemical quenching.
Proc. Natl. Acad. Sci. USA 110 (14) 5452-5456 (2013).

Althoff, T., Davies, K. M., Schulze, S., Joos, F., and Kühlbrandt, W.: GRecon: A method for the lipid reconstitution of membrane proteins.
Angew. Chem. Int. Ed. 51 8343-8347 (2012).

Davies, K. M., Anselmi, C., Wittig, I., Faraldo-Gómez, J.D., and Kühlbrandt, W.: Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae.
Proc. Natl. Acad. Sci. USA 109 13602-13607 (2012).

Hizlan, D., Robson, A., Whitehouse, S., Gold, V.A., Vonck, J., Mills, D., Kühlbrandt, W., and Collinson, I.: Structure of the SecY complex unlocked by a preprotein mimic.
Cell Reports 1 21-28 (2012).

Walter, A., Muzik, H., Vieker, H., Turchanin, A., Beyer, A., Gölzhäuser, A., Lacher, M., Steltenkamp, S., Schmitz, S., Holik, P., Kühlbrandt, W., and Rhinow, D.: Practical aspects of Boersch phase contrast electron microscopy of biological specimens.
Ultramicroscopy 116 62-72 (2012).

Althoff, T., Mills, D. J., Popot, J. L., and Kühlbrandt, W.: Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1.
EMBO J.
30 4652-4664 (2011).

Barton, B., Rhinow, D., Walter, A., Schröder, R., Benner, G., Majorovits, E., Matijevic, M., Niebel, H., Müller, H., Haider, M., Lacher, M., Schmitz, S., Holik, P., and Kühlbrandt, W.: In-focus electron microscopy of frozen-hydrated biological samples with a Boersch phase plate.
Ultramicroscopy 111 1696-1705 (2011).

Davies, K. M., Strauss, M., Daum, B., Kief, J.H., Osiewacz H. D., Rycovska, A., Zickermann, V., and Kühlbrandt, W.: Macromolecular organization of ATP synthase and complex I in whole mitochondria.
Proc. Natl. Acad. Sci. USA 108, 14121-14126 (2011).

Goswami, P., Paulino, C., Hizlan, D., Vonck, J. Yildiz, Ö., and Kühlbrandt, W. (2011). Structure of the archaeal Na+/H+ antiporter NhaP1 and functional role of transmembrane helix 1.
EMBO J. 30 439-449 (2011).

Köster, S., Pavkov-Keller, T., Kühlbrandt, W., and Yildiz, Ö.: Structure of human Na+/H+ exchanger NHE1 regulatory region in complex with CaM and Ca2+.
J. Biol. Chem.
286 40954-61 (2011).

Müller, M., Bamann, C., Bamberg, E., and Kühlbrandt, W.: Projection structure of channelrhodopsin-2 at 6 Å resolution by electron crystallography.
J. Mol. Biol. 414 86-95 (2011).

Rhinow, D., Bünfeld , M., Weber, N. E., Beyer, A., Gölzhäuser, A., Kühlbrandt, W., Hampp, N., and Turchanin, A.: Energy-filtered transmission electron microscopy of biological samples on highly transparent carbon nanomembranes. Ultramicroscopy 111 342-349 (2011).

Rhinow, D., Weber, N. E., Turchanin, A., Gölzhäuser, A., and Kühlbrandt, W.: Single-walled carbon nanotubes and nanocrystalline graphene reduce beam-induced movements in high-resolution electron cryo-microscopy of ice-embedded biological samples.
Appl. Phys. Lett. 99 133701 (2011).

Sommer, M. S., Daum, B., Gross, L. E., Weis, B. L. M., Mirus, O., Abram, L., Maier, U. G., Kühlbrandt, W., and Schleiff, E.: Chloroplast Omp85 proteins change orientation during evolution.
Proc. Natl. Acad. Sci. USA 108 13841-13846 (2011).

Tsai, C.-J., Khafizov, K., Hakulinen, J., Forrest, L. R., Krämer, R., Kühlbrandt, W., and Ziegler, C.: Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum.
 J. Mol. Biol. 407 368-381 (2011).

Wilk, L., Strauss, M., Rudolf, M., Nicolaisen, K., Flores, E., Kühlbrandt, W., and Schleiff, E.: Outer membrane continuity and septosome formation between vegetative cells in the filaments of Anabaena sp. PCC 7120.
Cell Microbiol. 13 1744-54 (2011).

Brust, D., Daum, B., Breunig, C.,  Hamann, A., Kühlbrandt, W., and Osiewacz, H. D.: Cyclophilin D links programmed cell death and organismal aging in Podospora anserina.
Aging Cell
9 761-775 (2010).

Damaghi, M., Bippes, C., Köster, S., Yildiz, Ö., Mari, S. A., Kühlbrandt, W., and Müller, D.: pH-Dependent interactions guide the folding and gate the transmembrane pore of the b-barrel membrane protein OmpG.
J. Mol. Biol. 397 878-882 (2010).

Damaghi, M., Sapra, K. T., Köster, S., Yildiz, Ö., Kühlbrandt, W., and Müller, D. J.: Dual energy landscape: the functional state of the β-barrel outer membrane protein G molds its unfolding energy landscape.
Proteomics 10 4151-4162 (2010).

Daum, B., Nicastro, D., Austin II, J., McIntosh, J. R., and Kühlbrandt, W.: Arrangement of photosystem-II and ATP synthase in chloroplast membranes of spinach and pea.
Plant Cell 22 1299-1312 (2010).

Gipson, P., Mills, D., Wouts, R., Grininger, M., Vonck, J., and Kühlbrandt, W.: Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy.
Proc. Natl. Acad. Sci. USA 107 9164-9169 (2010).

Korkmaz-Özkan, F., Köster, S., Kühlbrandt, W., Mäntele, W., and Yildiz, Ö.: Correlation between the OmpG secondary structure and its pH-dependent alterations monitored by FTIR.
J. Mol. Biol. 401 56-67 (2010).

Liao, P. N., Holleboom, C. P., Wilk, L., Kühlbrandt, W., and Walla, P. J.: Correlation of Car S1-Chl with Chl-Car S1 energy transfer supports the excitonic model in quenched light harvesting complex II.
J. Phys. Chem. B 114 15650-15655 (2010).

Mari, S. A., Köster, S., Bippes, C. A., Yildiz, Ö., Kühlbrandt, W., and Müller, D.:  pH-induced conformational change of the b-barrel-forming protein OmpG reconstituted into native E. coli lipids.
J. Mol. Biol. 396, 610-616 (2010).

Schulze, S., Köster, S., Geldmacher, U., Terwisscha van Scheltinga, A. C., and Kühlbrandt, W.: Structural basis of Na+-independent and cooperative substrate/product antiport in CaiT.
Nature 467 233-236 (2010).

Amarie, S., Wilk, L., Barros, T., Kühlbrandt, W., Dreuw, A., and Wachtveitl, J.: Properties of zeaxanthin and its radical cation bound to the minor light-harvesting complexes CP24, CP26 and CP29.
Biochim. Biophys. Acta - Bioenergetics 1787 (6) 747-752 (2009).

Appel, M., Hizlan, D., Vinothkumar, K. R., Ziegler, C., and Kühlbrandt, W.: Conformations of NhaA, the Na/H exchanger from Escherichia coli, in the pH-activated and ion-translocating states.
J. Mol. Biol. 388 659-672 (2009).

Barros, T. and Kühlbrandt, W.: Crystallisation, structure and function of plant light-harvesting Complex II.
Biochim. Biophys. Acta - Bioenergetics  1787 753-772 (2009).

Barros, T., Royant, A., Standfuss, J., Dreuw, A., and Kühlbrandt, W.: Crystal structure of plant light-harvesting complex shows the active, energy-transmitting state.
EMBO J. 28 298-306 (2009).

Džafić, E., Klein, O., Goswami, P., Kühlbrandt, W., and Mäntele, W.: Infrared spectroscopic study of the structural and functional properties of the Na+-/H+- antiporter MjNhaP1 from Methanococcus jannaschii.
Biochim. Biophys. Acta-Bioenergetics 1787 (6) 730-737 (2009).

Köster, S., Kühlbrandt, W. , and Yildiz, Ö.: Purification, crystallization and preliminary X-ray diffraction analysis of the FeoB G domain from Methanococcus jannaschii.
Acta Cryst. F65 684-687 (2009).

Köster, S., Wehner, M., Herrmann, C., Kühlbrandt, W., and Yildiz, Ö.: Structure and function of the FeoB G-domain from Methanococcus jannaschii.
J. Mol. Biol. 392 405-419 (2009).

Sapra, K. T., Damaghi, M., Köster, S. Yildiz, Ö., Kühlbrandt, W., and Müller, D.: One β-hairpin after the other: exploring mechanical unfolding pathways of the transmembrane β-barrel protein OmpG.
Angew. Chem. Int. Ed. 48 (44) 8306-8308 (2009).

Chintalapati, S., Al Kurdi, R., Terwisscha van Scheltinga, A. C., and Kühlbrandt, W.: Membrane structure of CtrA3, a copper transporting P-type ATPase from Aquifex aeolicus.
J. Mol. Biol. 378 (3) 581-595 (2008).

Hiller, M., Higman, V. A., Jehle, S., van Rossum, B. J., Kühlbrandt, W., and Oschkinat, H.: [2,3-13C]-labeling of aromatic residues - getting a head start in the magic-angle-spinning NMR assignment of membrane proteins.
J. Am. Chem. Soc. 130 408-409 (2008).

Lotz, M., Haase, W., Kühlbrandt, W., and Collinson, I.: Projection structure of YidC: a conserved mediator of membrane protein assembly.
J. Mol. Biol. 375 (4) 901-907 (2008).

Model, K., Meisinger, C., and Kühlbrandt, W.: Cryo-electron microscopy structure of a yeast mitochondrial preprotein translocase.
J. Mol. Biol. 383 (5) 1049-1057 (2008).

Rhinow, D. and Kühlbrandt, W.: Electron cryo-microscopy of biological specimens on conductive titanium–silicon metal glass films.
Ultramicroscopy 108 (7) 698-705 (2008).

Strauss, M., Hofhaus, G., Schröder, R. R., and Kühlbrandt, W.: Dimer ribbons of ATP synthase shape the inner mitochondrial membrane.
EMBO J. 27 1154-1160 (2008).

Amarie, S., Standfuss, J., Barros, T., Kühlbrandt, W., Dreuw, A., and Wachtveitl, J.: Carotenoid radical cations as a probe for the molecular mechanism of nonphotochemical quenching in oxygenic photosynthesis.
J. Phys. Chem. B 111 3481-3487 (2007).

Schmidt-Krey, I., Haase, W., Mutucumarana, V., Stafford, D. W., and Kühlbrandt, W.: Two-dimensional crystallization of human vitamin K-dependent gamma-glutamyl carboxylase.
J. Struct. Biol. 157 437-442 (2007).

Shastri, S., Vonck, J., Pfleger, N., Haase, W., Kühlbrandt, W., and Glaubitz, C.: Proteorhodopsin: characterisation of 2D crystals by electron microscopy and solid state NMR.
Biochim. Biophys. Acta 1768 3012-3019 (2007).

Yildiz, Ö., Kalthoff, C., Raunser, S., and Kühlbrandt, W.: Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake.
EMBO J. 26 589-599 (2007).

Kedrov A., Janovjak H., Ziegler C., Kuhlbrandt, W., and Muller, D. J.: Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli.
J. Mol. Biol. 355 2-8 (2006).

Palacios, M. A., Standfuss, J., Vengris, M., van Oort, B. F., van Stokkum, I. H. M., Kühlbrandt, W., van Amerongen, H., and van Grondelle, R.: A comparison of the three isoforms of the light-harvesting complex II using transient absorption and time-resolved fluorescence measurements.
Photosynth. Res. 88 269-285 (2006).

Raunser, S., Appel, M., Ganea C., Geldmacher-Kaufer, U., Fendler, K., and Kühlbrandt, W.: Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii.
Biochem. 45 12796-12805 (2006).

Raunser, S., Haase, W., Franke, C., Eckert, G. P., Müller, W. E., and Kühlbrandt, W.: Heterologously expressed GLT-1 associates in 200 nm protein-lipid islands.
Biophys. J. 91 3718-3726 (2006).

Schmidt-Krey, I., Haase, W., Mutucumarana, V., Stafford, D. W., and Kühlbrandt, W.: Two-dimensional crystallization of human vitamin K-dependent γ-glutamyl carboxylase.
J. Struct. Biol. 157 437-442 (2006).

Vinothkumar, K. R., Raunser, S., Jung, H., and Kühlbrandt, W.: Oligomeric structure of the carnitine transporter CaiT from Escherichia coli.
J. Biol. Chem. 281 4795-4801 (2006) .

Yildiz, Ö., Vinothkumar, K. R., Goswami, P., and Kühlbrandt, W.: Structure of the monomeric outer-membrane porin OmpG in the open and closed conformation.
EMBO J. 25 3702-3713 (2006).

Bostina, M., Mohsin, B., Kühlbrandt, W., and Collinson, I.: Atomic model of the E. coli membrane-bound protein translocation complex SecYEG.
J. Mol. Biol. 352 1035-1043 (2005).

Büchel, C. and Kühlbrandt, W.: Structural differences in the inner part of photosystem II between higher plants and cyanobacteria.
Photosynth. Res. 85 3-13 (2005).

Hiller, M., Krabben, L., Vinothkumar, K. R., Castellani, F., Van Rossum, B., Kühlbrandt, W., and Oschkinat, H.: Solid-state magic-angle spinning NMR of outer-membrane protein G from Escherichia coli.
ChemBioChem. 6 1679-1684 (2005).

Kedrov, A., Krieg, M., Ziegler, C., Kuhlbrandt, W., and Muller, D. J.: Locating ligand binding and activation of a single antiporter.
EMBO Rep. 6 668-674 (2005).

Raunser, S., Haase, W., Bostina, M., Parcej, D. N., and Kühlbrandt, W.: High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus.
J. Mol. Biol. 351 598-613 (2005).

Standfuss, J., Terwisscha van Scheltinga, A., Lamborghini, M., and Kühlbrandt, W.: Mechanisms of photoprotection and non-photochemical quenching in pea LHC-II at 2.5 Å resolution.
EMBO J. 24 919-928 (2005).

Vinothkumar, K. R., Smits, S. H. J., and Kühlbrandt, W.: pH-induced structural change in a sodium/proton antiporter from Methanococcus jannaschii.
EMBO J. 24 2720-2729 (2005).

Jahn, T. P., Møller, A. L. B., Zeuthen, T., Holm, L. M., Klærke, D. A., Mohsin, B., Kühlbrandt, W., and Schjoerring, J. K.: Aquaporin homologues in plants and mammals transport ammonia.
FEBS Lett. 574 31-36 (2004).

Kedrov, A., Ziegler, C., Janovjak, H., Kühlbrandt, W., and Müller, D. J.: Controlled unfolding and refolding of a single sodium-proton antiporter using atomic force microscopy.
J. Mol. Biol. 340 1143-1152 (2004).

Schmidt-Krey, I., Kanaoka, Y., Mills, D. J., Irikura, D., Haase, W., Lam, B. K., Austen, K. F., and Kühlbrandt, W.: Human leukotriene C4 synthase at 4.5 Å resolution in projection.
Structure 12 2009-2014 (2004).

Standfuss, J. and Kühlbrandt, W.: The three isoforms of the light-harvesting complex II - spectroscopic features, trimer formation, and functional roles.
J. Biol. Chem. 279 36884-36891 (2004).

Ziegler, C., Morbach, S., Schiller, D., Kramer, R., Tziatzios, C., Schubert, D., and Kühlbrandt, W.: Projection structure and oligomeric state of the osmoregulated sodium/glycine betaine symporter BetP of Corynebacterium glutamicum.
J. Mol. Biol. 337 1137-1147 (2004).

Rogl, H., Kühlbrandt, W., and Barth, A.: Light-induced changes in the chemical bond structure of light harvesting complex II probed by FTIR spectroscopy.
Biochem. 42 10223-10228 (2003).

Oates, J., Mathers, J., Mangels, D., Kühlbrandt W., Robinson, C., and Model, K.: Consensus structural features of purified bacterial TatABC complexes.
J. Mol. Biol. 330 277-286 (2003).

Rehling, P., Model, K., Brandner, K., Kovermann, P., Sickmann, A., Meyer, H. E., Kühlbrandt, W., Wagner, R., Truscott, K. N., and Pfanner, N.: Protein insertion into the mitochondrial inner membrane by a twin-pore translocase.
Science 299 1747-1751 (2003).

Schleiff, E., Soll, J., Kuchler, M., Kühlbrandt, W., and Harrer, R.: Characterization of the translocon of the outer envelope of chloroplasts.
J. Cell Biol. 160 541-551 (2003).

Meier, T., Matthey, U., von Ballmoos, C., Vonck, J., Krug von Nidda, T., Kühlbrandt, W., and Dimroth, P.: Evidence for structural integrity in the undecameric rotors isolation from sodium ATP synthases.
J. Mol. Biol. 325 389-397 (2003).

Kühlbrandt W., Zeelen, J., and Dietrich J.: Structure, mechanism and regulation of the Neurospora plasma membrane H+-ATPase.
Science 297 1692-1696 (2002).

Vonck, J., Krug von Nidda, T., Meier, T., Matthey, U., Mills, D. J., Kühlbrandt, W., and Dimroth, P.: Molecular architecture of the undecameric rotor of a bacterial Na+-ATP synthase.
J. Mol. Biol. 321 307-316 (2002).

Breyton, C., Haase, W., Rapoport, T. A., Kühlbrandt, W., and Collinson, I.: Three-dimensional structure of the bacterial protein-translocation complex SecYEG.
Nature 418 662-665 (2002).

Model, K., Prinz, T., Ruiz, T., Radermacher, M., Krimmer, T., Kühlbrandt, W., Pfanner, N., and Meisinger, C.: Protein translocase of the outer mitochondrial membrane: role of import receptors in the structural organization of the TOM complex.
J. Mol. Biol. 316 657-666 (2002).

Rogl, H., Schödel, R., Lokstein, H., Kühlbrandt, W., and Schubert, A.: Assignment of spectral substructures to pigment-binding sites in higher plant light-harvesting complex LHC-II.
Biochem. 41 2281 -2287 (2002).

Behlau, M., Mills, D. J., Quader, H., Kühlbrandt, W., and Vonck, J.: Projection structure of the monomeric porin OmpG at 6 Å resolution.
J. Mol. Biol. 305 71-77 (2001).

Collinson, I., Breyton, C., Duong, F., Tziatzios, C., Schubert, D., Or, E., Rapaport, T., and Kühlbrandt, W.: Projection structure  and oligomeric properties of a bacterial core protein translocase.
EMBO J. 20 2462-2471 (2001).

Jahn, T., Dietrich, J., Andersen, B., Leidvik, B., Otter, C., Briving, C., Kühlbrandt, W., and Palmgren, M. G.: Large scale expression, purification and 2D crystallization of recombinant plant plasma membrane H+-ATPase.
J. Mol. Biol. 309 465-476 (2001).

Lebeau, L., Lach, F., Vénien-Bryan, C., Renault, A., Dietrich, J., Jahn, T., Palmgren, M. G., Kühlbrandt, W., and Mioskowski, C.: Two-dimensional crystallization of a membrane protein on a detergent-resistant lipid monolayer.
J. Mol. Biol. 308 639-647 (2001).

Schmid, V., Thomé, P., Rühle, W., Paulsen, H., Kühlbrandt, W., and Rogl, H.: Chlorophyll b is involved in long-wavelength spectral properties of light-harvesting complexes LHC I and LHC II.
FEBS Lett. 499 27-31 (2001).

Braun, T., Philippsen, A., Wirtz, S., Borgnia, M. J., Agre, P., Kühlbrandt, W., Engel, A., and Stahlberg, H.: The 3.7 Å projection map of the glycerol facilitator GlpF: a variant of the aquaporin tetramer.
EMBO Reports
1 183-189 (2000).

Stahlberg, H., Braun, T., de Groot, B., Philippsen, A., Borgnia, M. J., Agre, P., Kühlbrandt, W., and Engel, A.: The 6.9-Å structure of GlpF: A basis for homology modeling of the glycerol channel from Escherichia coli.
J. Struct. Biol. 132 133-141 (2000).

Auer, M., Scarborough, G. A., and Kühlbrandt, W.: Surface crystallisation of the plasma membrane H+-ATPase on a carbon support film for electron crystallography.
J. Mol. Biol. 287 961-968 (1999).

Dietrich, J. and Kühlbrandt, W.: Purification and two-dimensional crystallization of highly active cytochrome b6f complex from spinach.
FEBS Lett. 463 97-102 (1999).

Rogl, H. and Kühlbrandt, W.: Mutant trimers of light-harvesting complex II exhibit altered pigment content and spectroscopic features.
Biochem. 38 16214-16222 (1999).

Stokes, D. L., Auer, M., Zhang, P., and Kühlbrandt, W.: Comparison of H+-ATPase and Ca2+-ATPase suggests that a large conformational change initiates P-type ion pump reaction cycles.
Curr. Biol. 9 672-679 (1999).

Williams, K. A., Geldmacher-Kaufer, U., Padan, E., Schuldiner, S., and Kühlbrandt, W.: Projection structure of NhaA, a secondary transporter from Escherichia coli at 4.0 Å resolution.
EMBO J. 18 3558-3563 (1999).

Auer, M., Scarborough, G. A., and Kühlbrandt, W.: Three-dimensional map of the plasma membrane H+ ATPase in the open conformation.
Nature 392 840-843 (1998).

Rhee, K. H., Morris, E. P., Barber, J., and Kühlbrandt, W.: Three-dimensional structure of the plant photosystem II reaction centre at 8 Å resolution.
Nature 396 283-286 (1998).

Rogl, H., Kosemund, K., Kühlbrandt, W., and Collinson, I.: Refolding of Escherichia coli produced membrane protein inclusion bodies immobilised by nickel chelating chromatography.
FEBS Lett. 432 21-26 (1998).

Rhee, K. H., Morris, E. P., Zheleva, D., Hankamer, B., Kühlbrandt, W., and Barber, J.: Two-dimensional structure of plant photosystem II at 8 Å resolution.
Nature 389 522-526 (1997).

Flachmann, R. and Kühlbrandt, W.: Crystallization and identification of an assembly defect of recombinant antenna complexes produced in transgenic tobacco plants.
Proc. Natl. Acad. Sci. USA 93 14966-14971 (1996).

Savage, H., Cyrklaff, M., Montoya, G., Kühlbrandt, W., and Sinning, I.: Two-dimensional structure of light harvesting complex II (LHCII) from the purple bacterium Rhodovulum sulfidophilum and comparison with LHCII from Rhodopseudomonas acidophila.
Structure 4 243-252 (1996).

Green, B. and Kühlbrandt, W.: Sequence conservation of light-harvesting and stress-response proteins in relation to the three-dimensional structure of LHC-II.
Photosynth. Res. 44 139-148 (1995).

Cyrklaff, M., Auer, M., Kühlbrandt, W., and Scarborough, G. A.: Two-dimensional  structure of the Neurospora crassa plasma membrane ATPase as determined by electron cryomicroscopy.
EMBO J. 14 1854-1857 (1995).

Flachmann, R. and Kühlbrandt, W.: Accumulation of plant antenna complexes is regulated by posttranscriptional mechanisms in tobacco.
Plant Cell 7 149-160 (1995).

Nussberger, S., Dekker, J. P., Kühlbrandt, W., van Bolhuis, B. M., van Grondelle, R., and van Amerongen, H.: Spectroscopic characterization of three different monomeric forms of the main chlorophyll a/b binding protein from chloroplast membranes.
Biochem. 33 14775-14783 (1994).

Hobe, S., Prytulla, S., Kühlbrandt, W., and Paulsen, H.: Trimerization and crystallization of reconstituted light-harvesting chlorophyll a/b complex. EMBO J. 13 3423-3429 (1994).

Cyrklaff, M. and Kühlbrandt, W.: High-resolution electron microscopy of biological specimens in cubic ice.
Ultramicroscopy 55 141-153 (1994).

Wang, D. N., Sarabia, V. E., Reithmeier, R. A., and Kühlbrandt, W.: Three-dimensional map of the dimeric membrane domain of the human erythrocyte anion exchanger, Band 3.
EMBO J. 13 3230-3235 (1994).

Kühlbrandt, W., Wang, D. N., and Fujiyoshi, Y.: Atomic model of plant light-harvesting complex by electron crystallography.
Nature 367 614-621 (1994).

Wang, D. N., Kühlbrandt, W., Sarabia, V. E., and Reithmeier, R. A.: Two-dimensional structure of the membrane domain of human band 3, the anion transport protein of the erythrocyte membrane.
EMBO J. 12 2233-2239 (1993).

Nussberger, S., Dörr, K., Wang, D. N., and Kühlbrandt, W.: Lipid-protein interactions in crystals of plant light-harvesting complex.
J. Mol. Biol. 234 347-356 (1993).

Wang, D. N. and Kühlbrandt, W.: Three-dimensional electron diffraction of plant light-harvesting complex.
Biophys. J. 61 287-297 (1992).

Butt, H. J., Wang, D. N., Hansma, P., and Kühlbrandt, W.: Effect of surface roughness of carbon support films on high-resolution electron diffraction of two-dimensional protein crystals.
Ultramicroscopy 36 307-318 (1991).

Kühlbrandt, W. and Wang, D. N.: Three-dimensional structure of plant light-harvesting complex determined by electron crystallography.
Nature 350 130-134 (1991).

Wang, D. N. and Kühlbrandt, W.: High-resolution electron crystallography of light-harvesting chlorophyll a/b-protein complex in three different media.
J. Mol. Biol. 217 691-699 (1991).

Kühlbrandt, W. and Downing, K. H.: Two-dimensional structure of plant light-harvesting complex at 3.7 Å resolution by electron crystallography.
J. Mol. Biol. 207 823-828 (1989).

Butler, P. J. G. and Kühlbrandt, W.: Determination of the aggregate size in detergent solution of the light-harvesting chlorophyll a/b-protein complex from chloroplast membranes.
Proc. Natl. Acad. Sci. USA 85 3797-3801 (1988).

Kühlbrandt, W.: Structure of light-harvesting chlorophyll a/b protein complex from plant photosynthetic membranes at 7 Å resolution in projection.
J. Mol. Biol. 202 849-864 (1988).

Kühlbrandt, W. and Barber, J.: Separation of phosphorylated and unphosphorylated light-harvesting chlorophyll a/b-protein complex by column chromatography.
Biochim. Biophys. Acta 934 118-122 (1988).

Kühlbrandt, W., Becker, A., and Mäntele, W.: Chlorophyll dichroism of three-dimensional crystals of the light-harvesting chlorophyll a/b-protein complex.
FEBS Lett.
226 275-279 (1988).

Ide, J. P., Klug, D., Kühlbrandt, W., Giorgi, L., and Porter, G.: The state of detergent-solubilized light-harvesting chlorophyll a/b-protein complex as monitored by picosecond time-resolved fluorescence spectroscopy and circular dichroism.
Biochim. Biophys. Acta 893 349-364 (1987).

Kühlbrandt, W.: Three-dimensional crystals of the light-harvesting chlorophyll a/b protein complex from pea chloroplasts.
J. Mol. Biol. 194 757-762 (1987).

Stark, W., Kühlbrandt, W., Wildhaber, I., Wehrli, E., and Mühlethaler, K.: The structure of the photoreceptor unit of Rhodopseudomonas viridis.
EMBO J. 3 777-783 (1984).

Kühlbrandt, W.: Three-dimensional structure of the light-harvesting chlorophyll a/b-protein complex.
Nature 307 478-480 (1984).

Furrer, A., Stöckli, A., Hälg, A., Kühlbrandt, W., Wehrli, E. & Mühlethaler, K.: Light-induced dynamics of chlorophyll systems studied by neutron spectroscopy.
Helvetica Phys. Acta 56 655-662 (1983).

Kühlbrandt, W., Thaler, T., and Wehrli, E.: The structure of membrane crystals of the light-harvesting chlorophyll a/b protein complex.
J. Cell Biol. 96 1414-1424 (1983).

Kühlbrandt, W.: Discrimination of protein and nucleic acids by electron microscopy using contrast variation.
Ultramicrosopy 7 221-232 (1982).

Kühlbrandt, W. and Unwin, P. N.: Distribution of RNA and protein in crystalline eukaryotic ribosomes.
J. Mol. Biol. 156 431-448 (1982).

Kühlbrandt, W. and Garrett, R. A.: A ribonucleoprotein core in the 50 S ribosomal subunit of Escherichia coli.
FEBS Lett. 94 207-212 (1978).

Kühlbrandt, W., Luger, P., and Rewicki, D.: Hydrocarbon azaisologues-structure and disorder.
Z. Kristallogr. 146, 156-156 (1977).

Neidle, S., Kühlbrandt, W., and Achari, A.: The crystal structure of an orthorhombic form of adenosine-5’-monophosphate.
Acta Cryst. B32 1850-1855 (1976).


B - Invited reviews and book chapters: present to 1980


Kühlbrandt, W.: Three in a row - how sodium ions cross the channel.
EMBO J. 35 (8) 793-795 (2016).

Kühlbrandt, W. and Davies, K. M.: Rotary ATPases: A New Twist to an Ancient Machine.
Trends Biochem. Sci.
41 (1) 106-116 (2016).

Subramaniam, S., Kühlbrandt, W., and Henderson, R.: CryoEM at IUCrJ: a new era.
IUCrJ 3 (1) 3-7 (2016).

Kühlbrandt, W.: Structure and function of mitochondrial membrane protein complexes.
BMC Biol. 13:89 11 pp., online, doi: 10.1186/s12915-015-0201-x (2015).

Kühlbrandt, W.: Microscopy: Cryo-EM enters a new era.
eLife 3:e03678; 4 pp. (2014).

Kühlbrandt, W.: The Resolution Revolution.
Science 343 1443-1444 (2014).

Kühlbrandt, W.: Chap. 1. Introduction to Electron Crystallography.
pp. 1-16.
In: Schmidt-Krey, I. and Cheng, Y. (eds.), Electron Crystallography of Soluble and Membrane Proteins: Methods and Protocols; Series: Methods in Molecular Biology 955, doi: 10.1007/978-1-62703-176-9_1, Springer Science+Business Media Heidelberg (2013).

Abeyrathne, P. D., Arheit, M., Kebbel, F., Castano-Diez, D., Goldie, K. N., Chami, M., Renault, L. Kühlbrandt, W., and Stahlberg, H.: Analysis of 2-D Crystals of Membrane Proteins by Electron Microscopy (Chap. 1.15).
In: Comprehensive Biophysics 1, Biophysical Techniques for Structural Characterization of Macromolecules, ed. Egelman, E. H.,Dson, H. J., Elsevier, B. V. Academic Press, Oxford, pp. 277-310 (2012).

Kühlbrandt, W.: Combining Cryo-EM and X-ray Crystallography to Study Membrane Protein Structure and Function.
In: Macromolecular Crystallography: Deciphering the Structure, Function and Dynamics of Biological Molecules (NATO Science for Peace and Security Series-A: Chemistry and Biology), Springer Science and Business Media B. V., Dordrecht, The Netherlands, eds. M. A. Carrondo and P. Spadon; Chapter 9, pp. 93-101 (2012).

Popot, J. L., Althoff, T., Bagnard, D., Banères, J. L., Bazzacco, P., Billon-Denis, E., Catoire, L. J., Champeil, P., Charvolin, D., Cocco, M. J., Crémel, G., Dahmane, T., de la Maza, L. M., Ebel, C., Gabel, F., Giusti, F., Gohon, Y., Goormaghtigh, E., Guittet, E., Kleinschmidt, J. H., Kühlbrandt, W., Le Bon, C., Martinez, K. L., Picard, M., Pucci, B., Sachs, J. N., Tribet, C., van Heijenoort, C., Wien, F., Zito, F., and Zoonens, M.: Amphipols from A to Z.
Annu. Rev. Biophys. 40 379-408 (2011).

Daum, B. and Kühlbrandt, W.: Electron tomography of plant thylakoid membranes.
J. Exp. Bot.
62 (7) 2393-2402 (2011).

Barros, T. and Kühlbrandt, W.: Crystallisation, structure and function of plant light-harvesting complex II.
Biochim. Biophys. Acta - Bioenergetics 1787 753-772 (2009).

Kühlbrandt, W.: Biology, structure and mechanism of P-type ATPases.
Nat. Rev. Mol. Cell Biol. 5 282-295 (2004).

Kühlbrandt, W.: Structural Biology – dual approach to a light problem.
Nature News and Views 426 399-400 (2003).

Kühlbrandt, W.: Two-dimensional crystallization of membrane proteins: a practical guide.
In: Membrane protein purification and crystallization: a practical guide (Hunte, C., Jagow, G. von, Schägger, H. eds.), 2nd edition, 253-284 Academic Press, San Diego (2003).

Kühlbrandt, W.: Chlorophylls galore.
Nature News and Views 411 896-899 (2001).

Kühlbrandt, W.: Bacteriorhodopsin – the movie.
Nature News and Views 406 569-570 (2000).

Kühlbrandt, W. and Gouaux, E.: Membrane proteins (editorial overview).
Curr. Opin. Struct. Biol. 9 445-447 (1999).

Kühlbrandt, W. and Williams, K. A.: Analysis of macromolecular structure and dynamics by electron cryo-microscopy.
Curr. Opin. Chem. Biol. 3 537-543 (1999).

Barber, J. and Kühlbrandt, W. Photosystem II.
Curr. Opin. Struct. Biol. 9 469-475 (1999).

Kühlbrandt, W., Auer, M., and Scarborough, G. A.: Structure of the P-type ATPases.
Curr. Opin. Struct. Biol. 8 510-516 (1998).

Kühlbrandt, W.: Pumping ions (News and Views).
Nature Struct. Biol. 4 773-773 (1997).

Kühlbrandt, W.: Structure and function of bacterial light-harvesting complexes.
Structure 3 521-525 (1995).

Kühlbrandt, W.: Photosynthesis - many wheels make light work (News and Views).
Nature
374 497-498 (1995).

Kühlbrandt, W.:Structure and function of the plant light-harvesting complex, LHC-II.
Curr. Opin. Struct. Biol. 4 519-528 (1994).

Kühlbrandt, W. and Gennis, R. B.: Membrane proteins (editorial overview).
Curr. Opin. Struct. Biol. 4 517-518 (1994).

Kühlbrandt, W.: Electron crystallography of membrane proteins.
In: Membrane protein structural methods (S. H. White, Ed.) Oxford University Press, pp. 206-223 (1994).

Gennis, R. M. and Kühlbrandt, W.: Membrane proteins (editorial overview).
Curr. Opin. Struct. Biol. 3 499-500 (1993).

Kühlbrandt, W.: Membrane proteins (editorial overview).
Curr. Opin. Struct. Biol. 2 503-504 (1992).

Kühlbrandt, W.: Two-dimensional crystallization of membrane proteins.
Quart. Rev. Biophys. 25 1-49 (1992).

Kühlbrandt, W.: Membrane proteins (editorial overview).
Curr. Opin. Struct. Biol. 1 531-533 (1991).

Kühlbrandt, W.: Crystallization of the light-harvesting chlorophyll a/b-protein complex.
In: Crystallization of Membrane Proteins (Michel, H., ed.) CRC Press, Boca Raton, Florida, pp. 155-166 (1990).

Kühlbrandt, W.: Three-dimensional crystallization of membrane proteins.
Quart. Rev. Biophys. 21 429-477 (1988).

Kühlbrandt, W.: Structure of the light-harvesting chlorophyll a/b-protein complex.
In: Photosynthetic light-harvesting systems: structure and function (H. Scheer and S. Schneider, eds.) W. de Gruyter & Co., Berlin, pp. 211-215 (1988).

Kühlbrandt, W.: Photosynthetic membranes and membrane proteins.
In: Electron microscopy of proteins, Vol. 6 (R. Harris and R.W. Horne, eds) Academic Press, London. pp. 155-207 (1987).

Kühlbrandt, W. and Unwin, P. N. T.: Structure analysis of stained and unstained two-dimensional ribosome crystals.
In: Electron microscopy at molecular dimensions (W. Baumeister  and W. Vogell, eds.) Springer Verlag, Berlin, pp.108-116 (1980).

Contact:

Max Planck Institute of Biophysics

Prof. Dr. Werner Kühlbrandt, Managing Director
Department of Structural Biology
Secretary: Monika Hobrack

Phone: +49 (0) 69 6303-3001
Fax: +49 (0) 69 6303-3002
E-mail: monika.hobrack(at)biophys.mpg.de

Kühlbrandt - Group members:

Postdocs

Ph. D. Students

  • Thomas Bausewein
  • Lea Dietrich
  • Bianca Eisel
  • Thomas Ellinghaus
  • Davide Floris
  • Niklas Klusch

Research assistants

  • Heidi Betz
  • Sabine Häder
  • Dipl.-Chem. Brigitte Holfelder

EM facilities

  • Dr. Susann Kaltwasser
  • Mark Linder
  • Deryck Mills
  • Simone Prinz

IT facilities

  • Dr. Juan Castillo