Publications 2007 – Molecular Membrane Biology

Barleben, L., S. Panjikar, M. Ruppert, J. Koepke and J. Stöchigt: Molecular Architecture of Strictosidine Glucosidase: The Gateway to the Biosynthesis of the Monoterpenoid Indole Alkaloid Family. The Plant Cell 19, 2886-2897 (2007).

Cheap, H., J. Tandori, V. Derrien, M. Benoit, P. de Oliveira, J. Koepke, J. Lavergne, P. Maroti and P. Sebban: Evidence for Delocalized Anticooperative Flash Induced Proton Binding as Revealed by Mutants at the M266His Iron Ligand in Bacterial Reaction Centers. Biochemistry 46, 4510-4521 (2007).

Chillakuri, C., Ch. Reinhart and H. Michel: C-terminal truncated cannabinoid receptor 1 co-expressed with G protein trimer in Sf9 cells exist in a precoupled state and show constitutive activity. FEBS Journal 274, 6106-6115 (2007).

De Oliveira, P., A. Ranjbari, L. Baciou, T. Bizouarn, G. Ollesch, U. Ermler, P. Sebban, B. Keita and L. Nadjo: Preliminary electrochemical studies of the flavohaemoprotein from Ralstonia eutropha entrapped in a film of methyl cellulose: activation of the reduction of dioxygen. Bioelectrochemistry 70, 185-191 (2007).

Klammt, Ch., A. Srivastava, N. Eifler, F. Junge, M. Beyermann, D. Schwarz, H. Michel, V. Doetsch and F. Bernhard: Functional analysis of cell-free produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation. FEBS J. 274, 3257-3269 (2007).

Klingen A.R., H. Palsdottir, C. Hunte and M. Ullmann: Redox-linked protonation state changes in cytochrome bc1 identified by Poisson-Boltzmann electrostatics calculations. Biochim. Biophys. Acta 1767, 204-221 (2007).

Koepke, J., E.-M Krammer, A.R. Klingen, P. Sebban, G.M. Ullmann and G. Fritzsch: pH modulates the quinone position in the photosynthetic reaction center from Rhodobacter sphaeroides in the neutral and charge separated states. J. Mol. Biol. 371, 396-409 (2007).

Lancaster, C.R.D.: Structures of Reaction Centers in Anoxygenic Bacteria. In: Primary Processes of Photosynthesis. Principles and Apparatus. Part 2: Reaction Centers / Photosystems, Electron Transport Chains, Photophosphorylation and Evolution (Renger, G., Ed.), Royal Society of Chemistry, Cambridge, pp. 5-56  (2007).

Lancaster, C. R. D., C. Hunte, J. Kelley III, B. L. Trumpower and R. Ditchfield : A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex. J. Mol. Biol. 368, 197-208 (2007).

Olkhova, E., E. Padan and H. Michel: The influence of protonation states on the dynamics of the NhaA antiporter from Escherichia coli. Biophys. J.92, 3784-3791 (2007).

Plewnia G, K. Schulze, C. Hunte, R. Tampé and J. Koch: Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1. J. Mol. Biol. 369, 95-107 (2007).

Schemberg, J., K. Schneider, U. Demmer, E. Warkentin, A. Müller and U. Ermler: A multitude of pocket templated metal-oxide based individual cluster nucleations in a molybdenum/tungsten storage protein cavity. Angewandte Chemie Int. Ed. 46, 2408-2413 (2007).

Screpanti, E and C. Hunte: Discontinuous membrane helices in transport proteins and their correlation with function. J. Struct. Biol. 159, 261-267 (2007).

Seedorf, H., C.H. Hagemeier, S. Shima, R. K. Thauer, E. Warkentin and U. Ermler: Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein from methanogenic archaea catalysing the reduction of O2 to H2O. FEBS J. 274, 1588-1599 (2007).

Shukla, A.K., W. Haase, C. Reinhart and H. Michel: Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. Int. J. Biochem. Cell Biol. 39, 931-942 (2007).

Shukla, A.K., W. Haase, C. Reinhart and H. Michel: Heterologous expression and characterization of the recombinant bradykinin B2 receptor using the methylotrophic yeast Pichia pastoris. Protein Expression Purification 55, 1-8 (2007).

Srinivasan, V., D.J.A. Netz, H. Webert, J. Mascarenhas, A.J. Pierik, H. Michel and R. Lill: Structure of the Yeast WD40 Domain Protein Cia1, a Component Acting Late in Iron-Sulfur Protein Biogenesis. Structure 15, 1246-1257 (2007).

Wedemeyer, U., G. Peng, H. Michel and K. Hartung: The protein AQ_1862 from the hyperthermophilic bacterium Aquifex aeolicus is a porin and contains two simultaneous conductance pathways of different selectivity. Biophys. J. 93, 2667-2677 (2007).

Wenz, T., R. Covian, P. Hellwig, F. MacMillan, B. Meunier, B. L. Trumpower and C. Hunte: Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III. J. Biol. Chem. 282, 3977-3988 (2007).


Ph.D. Theses

Cenacchi, L.: Heterologous Production and Characterization of Two Distinct Di-Heme Containing Membrane Integral Cytochrome b561 Enzymes from Arabidopsis thaliana. Frankfurt 2007.

Chillakuri, C.: Purification and Characterization of Heterologously Produced Cannabinoid Receptor 1 and G proteins. Frankfurt 2007.

Griesbach, J.: The human GPCR Nicotinic Acid Receptor 1: Heterologous Overproduction in Pichia pastoris and the Reconstitution of its complex with β-Arrestin 1 in vivo and in vitro. Frankfurt 2007.

Herzog, E.: Theoretical Investigation of Transmembrane Electron Coupled Proton Transfer in Quinol: Fumarate Reductase from Wolinella succinogenes. Frankfurt 2007.

Juhnke, H.: Molekularbiologische und biochemische Charakterisierung der “Succinat-Dehydrogenase” aus Wolinella succinogenes. Frankfurt 2007.

Kirchberg, K.: Untersuchung der Protonenbewegung während des O->E Schrittes im katalytischen Zyklus der Cytochrom-c-Oxidase von Paracoccus denitrificans. Frankfurt 2007.

Mir, S.H.: Generation of recombinant antibodies against membrane proteins by phage display. Frankfurt 2007.

Rajendran, C.: Structural studies on terminal oxidases and an electron donor to a terminal oxidase. Frankfurt 2007.

Roy, A.: Development of a novel approach and a new expression system for the production and crystallization of human G protein-coupled receptors. Frankfurt 2007.

Surade, S.: Structural Genomics on Prokaryotic Membrane Proteins. Frankfurt 2007.

Srivastava, A.: Production, Biochemical Characterization and Preliminary Structural Studies of Human Endothelin B Receptor in its Ligand-bound State. Frankfurt 2007.

Tiwari, S.: Establishment of an Escherichia coli cell-free expression system for the large scale production of selected membrane proteins. Frankfurt 2007.

Wedemeyer, U.: Functional and Structural Membrane Proteomics using Aquifex aeolicus. Frankfurt 2007.


Diploma Theses

Schäfer, H.: Herstellung eines löslichen GPCR-Signalkomplexes. Kassel / Frankfurt 2007.

Schleidt, P.: Charakterisierung von durch gezielten Aminosäureaustausch generierten Varianten der Chinol:Fumarat-Reduktase aus Wolinella succinogenes. Frankfurt 2007.

Contact:

Max Planck Institute of Biophysics

Prof. Dr. Dr. h.c. Hartmut Michel, Managing Director
Department of Molecular Membrane Biology
Secretary: S. McCormack

Phone: +49 (0) 69 6303-1001
Fax: +49 (0) 69 6303-1002

E-mail: secretariat.michel(at)biophys.mpg.de