Hartmut Michel: Molecular Membrane Biology – Department Publications

Weiss, H. M.; Haase, W.; Michel, H.; Reiländer, H.: Expression of functional mouse 5-HT_5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological characterization and localization. FEBS Letters 377 (3), pp. 451 - 456 (1995)

Ermler, U.; Siddiqui, R. A.; Cramm, R.; Friedrich, B.: Crystal structure of the flavohemoglobin from Alcaligenes eutrophus at 1.75 A resolution. The EMBO Journal 14 (24), pp. 6067 - 6077 (1995)

Postina, R.; Fahrenholz, F.: Total in vitro synthesis of plasmid DNA facilitates site-directed mutagenesis. Analytical Biochemistry 232 (2), pp. 254 - 258 (1995)

Schiweck, W.; Skerra, A.: Fermenter Production of an Artificial Fab Fragment, Rationally Designed for the Antigen Cystatin, and Its Optimized Crystallization Through Constant Domain Shuffling. Proteins: Structure, Function, and Bioinformatics 23 (4), pp. 561 - 565 (1995)

Marheineke, K.; Bach, M.; Haase, W.; Reiländer, H.: High level production and localization of bovine rod cGMP-gated cation channel subunit 1 in baculovirus-infected insect cells and Saccharomyces cerevisiae. Biochemical and Biophysical Research Communications 215 (3), pp. 961 - 967 (1995)

Gimpl, G.; Klein, U.; Reiländer, H.; Fahrenholz, F.: Expression of the Human Oxytocin Receptor in Baculovirus-infected Insect Cells: High-Affinity Binding Is Induced by a Cholesterol-Cyclodextrin Complex. Biochemistry 34 (42), pp. 13794 - 13801 (1995)

Hu, X.; Xu, D.; Hamer, K.; Schulten, K.; Koepke, J.; Michel, H.: Predicting the structure of the light-harvesting complex II of Rhodospirillum molischianum. Protein Science 4 (9), pp. 1670 - 1682 (1995)

Klein, U.; Gimpl, G.; Fahrenholz, F.: Alteration of the Myometrial Plasma Membrane Cholesterol Content with ß-Cyclodextrin Modulates the Binding Affinity of the Oxytocin Receptor. Biochemistry 34 (42), pp. 13784 - 13793 (1995)

Ostermeier, C.; Iwata, S.; Ludwig, B.; Michel, H.: F_v fragment-mediated crystallization of the membrane protein bacterial cytochrome c oxidase. Nature Structural and Molecular Biology 2 (10), pp. 842 - 846 (1995)

Dohse, B.; Mathis, P.; Wachtveitl, J.; Laussermair, E.; Iwata, S.; Michel, H.; Oesterhelt, D.: Electron Transfer from the Tetraheme Cytochrome to the Special Pair in the Rhodopseudomonas viridis Reaction Center: Effect of Mutations of Tyrosine L162. Biochemistry 34 (36), pp. 11335 - 11343 (1995)

Iwata, S.; Ostermeier, C.; Ludwig, B.; Michel, H.: Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature 376 (6542), pp. 660 - 669 (1995)

Tsiotis, G.; Haase, W.; Engel, A.; Michel, H.: Isolation and structural characterization of trimeric cyanobacterial photosystem I complex with the help of recombinant antibody fragments. European Journal of Biochemistry 231 (3), pp. 823 - 830 (1995)

Beckers, T.; Marheineke, K.; Reiländer, H.; Hilgard, P.: Selection and characterization of mammalian cell lines with stable over-expression of human pituitary receptors for gonadoliberin. European Journal of Biochemistry 231 (3), pp. 535 - 543 (1995)

Cao, Y.-J.; Gimpl, G.; Fahrenholz, F.: The amino-terminal fragment of the adenylate cyclase activating polypeptide (PACAP) receptor functions as a high affinity PACAP binding domain. Biochemical and Biophysical Research Communications 212 (2), pp. 673 - 680 (1995)

Visschers, R. W.; Germeroth, L.; Michel, H.; Monshouwer, R.; van Grondelle, R.: Spectroscopic properties of the light-harvesting complexes from Rhodospirillum molischianum. Biochimica et Biophysica Acta, Bioenergetics 1230 (3), pp. 147 - 154 (1995)

Baciou, L.; Michel, H.: Interruption of the Water Chain in the Reaction Center from Rhodobacter sphaeroides Reduces the Rates of the Proton Uptake and of the Second Electron Transfer to Q_B. Biochemistry 34 (25), pp. 7967 - 7972 (1995)

Kleymann, G.; Ostermeier, C.; Heitmann, K.; Haase, W.; Michel, H.: Use of Antibody Fragments (Fv) in Immunocytochemistry. Journal of Histochemistry and Cytochemistry 43 (6), pp. 607 - 614 (1995)

Kleymann, G.; Iwata, S.; Wiesmüller, K.-H.; Ludwig, B.; Haase, W.; Michel, H.: Immunoelectron microscopy and epitope mapping with monoclonal antibodies suggest the existence of an additional N-terminal transmembrane helix in the cytochrome b subunit of bacterial ubiquinol: cytochrome-c oxidoreductases. European Journal of Biochemistry 230 (1), pp. 359 - 363 (1995)

Ermler, U.; Siddiqui, R. A.; Cramm, R.; Schröder, D.; Friedrich , B.: Crystallization and preliminary X‐ray diffraction studies of a bacterial flavohemoglobin protein. Proteins: Structure, Function, and Bioinformatics 21 (4), pp. 351 - 353 (1995)

Ufer, E.; Postina, R.; Gorbulev, V.; Fahrenholz, F.: An extracellular residue determines the agonist specificity of V₂ vasopressin receptors. FEBS Letters 362 (1), pp. 19 - 23 (1995)

Kojro, E.; Fahrenholz, F.: Ligand-induced cleavage of the V₂ vasopressin receptor by a plasma membrane metalloproteinase. The Journal of Biological Chemistry 270 (12), pp. 6476 - 6481 (1995)

Deisenhofer, J.; Epp, O.; Sinning, I.; Michel, H.: Crystallographic refinement at 2.3 A resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis. Journal of Molecular Biology (London) 246 (3), pp. 429 - 457 (1995)

Kleymann, G.; Ostermeier, C.; Ludwig, B.; Skerra, A.; Michel, H.: Engineered Fv Fragments as a Tool for the One-Step Purification of Integral Multisubunit Membrane Protein Complexes. Nature Biotechnology 155, pp. 155 - 160 (1995)

Dübel, S.; Breitling, F.; Kontermann, R.; Schmidt, T.G.; Skerra, A.; Little, M.: Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv). Journal of Immunological Methods 178 (2), pp. 201 - 209 (1995)

Kreis-Kleinschmidt, V.; Fahrenholz, F.; Kojro, E.; Kröger, A.: Periplasmic sulphide dehydrogenase (Sud) from Wolinella succinogenes: isolation, nucleotide sequence of the sud gene and its expression in Escherichia coli. European Journal of Biochemistry 227 (1-2), pp. 137 - 142 (1995)

Vasudevan, S.; Hulme, E. C.; Bach, M.; Haase, W.; Pavia, J.; Reiländer, H.: Characterization of the rat m3 muscarinic acetylcholine receptor produced in insect cells infected with recombinant baculovirus. European Journal of Biochemistry 227 (1-2), pp. 466 - 475 (1995)

Klein, U.; Jurzak, M.; Gerstberger, R.; Fahrenholz, F.: A new tritiated oxytocin receptor radioligand—Synthesis and application for localization of central oxytocin receptors. Peptides 16 (5), pp. 851 - 857 (1995)

Muegge, I.; Ermler, U.; Fritzsch, G.; Knapp, E. W.: Free Energy of Cofactors at the Quinone-Q_A Site of the Photosynthetic Reaction Center of Rhodobacter sphaeroides Calculated by Minimizing the Statistical Error. The Journal of Physical Chemistry 99 (51), pp. 17917 - 17925 (1995)

Ostermeier, C.; Essen, L.-O.; Michel, H.: Crystals of an antibody F_V fragment against an integral membrane protein diffracting to 1.28 Å resolution. Proteins: Structure, Function, and Bioinformatics 21, pp. 74 - 77 (1995)

Lancaster, C. R. D.; Ermler, U.; Michel, H.: The Structures of Photosynthetic Reaction Centers from Purple Bacteria as Revealed by X-Ray Crystallography. In: Advances in Photosynthesis and Respiration, Vol. 2, pp. 503 - 526 (Eds. Blankenship , R. E.; Madigan , M. T.; Bauer, C. E.). Kluwer Academic Publishers 1995, Springer, Dordrecht (1995)

Essen, L.-O.: Protein Design mit Antikörpern: Generierung und röntgenkristallographische Charakterisierung synthetischer Antigenbindungsstellen. Dissertation, 199 pp., Fachbereich Biochemie, Pharmazie, Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Müller, H. N.: Konstruktion eines Lipocalins mit neuen Eigenschaften. Dissertation, 126 pp., Fachbereich Biochemie, Pharmazie und Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Ostermeier, C.: Kristallisation des Membranproteinkomplexes Cytchrome c Oxidase mit Hilfe eines Antikkörpers-Fv-Fragmentes. Dissertation, 204 pp., Fachbereich Chemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Salvestrin, H. G.: Die Kinetik des Elektronentransfers von der Cytochrome-c-Untereinheit zum primären Donor in Einkristallen des photosynthetischen Reaktionszentrums von Rhodopseudomonas viridis. Dissertation, 161 pp., Fachbereich Biochemie, Pharmazie und Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Schmidt, F.: Das Bilin-Bindungsprotein aus Pieris brassicae - die ß-Barrel Proteinarchitektur als Grundlage für die evolutive Generierung von Rezeptormolekülen mit neuen Bindungseigenschaften. Dissertation, 195 pp., Fachbereich Biochemie, Pharmazie, Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Skerra, A.: Molekulares Design von Proteinen mit neuen Bindungseigenschaften. Habilitation, Fachbereich Biochemie, Pharmazie und Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1995)

Schmitz, A. A. P.: Synthese einer Affinitätsmatrix zur Aufreinigung eines heterolog produzierten Serotoninrezeptors. Diploma, 95 pp., Fachbereich Chemie, Philipps-Universität Marburg, Marburg, Germany (1995)

Bundschuh, T.: Röntgenkristallographische Untersuchung des Reaktionszentrums von Rhodobacter sphaeroides mit ausgetauschtem Chinon A. Diploma, 114 pp., Institut für Organische Chemiw, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (1995)