Hartmut Michel: Molecular Membrane Biology – Department Publications
Journal Article (26)
2006
Journal Article
103 (50), pp. 18917 - 18922 (2006)
Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
45 (50), pp. 15049 - 15055 (2006)
Experimental Evidence for Proton Motive Force-Dependent Catalysis by the Diheme-Containing Succinate:Menaquinone Oxidoreductase from the Gram-Positive Bacterium Bacillus licheniformis. Biochemistry
Journal Article
C62 (12), pp. 0671 - 0673 (2006)
2-Hydroxy-2-3-(3-oxobutyl)naphtalene-1,4-dione. Acta Crystallographica, Section C: Crystal Structure Communications
Journal Article
50 (1), pp. 118 - 127 (2006)
Dot-blot immunodetection as a versatile and high-throughput assay to evaluate recombinant GPCRs produced in the yeast Pichia pastoris. Protein Expression and Purification
Journal Article
580 (25), pp. 5934 - 5940 (2006)
Biochemical and electron microscopic characterization of the F1F0 ATP Synthase from the hyperthermophilic eubacterium Aquifex aeolicus. FEBS Letters
Journal Article
25 (20), pp. 4963 - 4970 (2006)
Evidence for transmembrane proton transfer in a dihaem-containing membrane protein complex. The EMBO Journal
Journal Article
99 (3), pp. 868 - 877 (2006)
Functional Overexpression and Characterization of Human Bradykinin Subtype 2 Receptor in Insect Cells Using the Baculovirus System. Journal of Cellular Biochemistry
Journal Article
349 (1), pp. 6 - 14 (2006)
Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells. Biochemical and Biophysical Research Communications
Journal Article
27 (13), pp. 1534 - 1547 (2006)
Energy Barriers of Proton Transfer Reactions Between Amino Acid Side Chain Analogs and Water from ab initio Calculations. Journal of Computational Chemistry
Journal Article
362 (2), pp. 192 - 202 (2006)
Crucial Steps in the Structure Determination of the Na+/H+ Antiporter NhaA in its Native Conformation. Journal of Molecular Biology (London)
Journal Article
15 (9), pp. 2178 - 2189 (2006)
Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Science
Journal Article
1757 (8), pp. 988 - 995 (2006)
Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
45 (30), pp. 9042 - 9052 (2006)
Probing the Role of E272 in Quinol Oxidation of Mitochondrial Complex III. Biochemistry
Journal Article
580 (17), pp. 4261 - 4265 (2006)
Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells. FEBS Letters
Journal Article
7 (2), pp. 77 - 91 (2006)
Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. Journal of Structural and Functional Genomics
Journal Article
358 (3), pp. 798 - 809 (2006)
The Crystal Structure of the Apoenzyme of the Iron-Sulphur Cluster-free Hydrogenase. Journal of Molecular Biology (London)
Journal Article
15 (5), pp. 1115 - 1126 (2006)
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Science
Journal Article
387 (5), pp. 569 - 576 (2006)
Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system. Biological Chemistry
Journal Article
18 (4), pp. 907 - 920 (2006)
The Structure of Rauvolfia serpentina Strictosidine Synthase Is a Novel Six-Bladed β-Propeller Fold in Plant Proteins. The Plant Cell
Journal Article
395 (1), pp. 191 - 201 (2006)
Heterologous production in Wolinella succinogenes and characterization of the quinol:fumarate reductase enzymes from Helicobacter pylori and Campylobacter jejuni. Biochemical Journal
Journal Article
357 (3), pp. 870 - 879 (2006)
The structure of a Formylmethanofuran: Tetrahydromethanopterin Formyltransferase in Complex with its Coenzymes. Journal of Molecular Biology (London)
Journal Article
45 (9), pp. 2960 - 2967 (2006)
Reaction Mechanism of the Iron-Sulfur Flavoenzyme Adenosine-5 '-Phosphosulfate Reductase Based on the Structural Characterization of Different Enzymatic States. Biochemistry
Journal Article
103 (8), pp. 2629 - 2634 (2006)
Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
580 (5), pp. 1345 - 1349 (2006)
The role of tryptophan 272 in the Paracoccus denitrificans cytochrome c oxidase. FEBS Letters
Journal Article
45 (2), pp. 343 - 351 (2006)
Semliki Forest Virus vectors for overexpression of 101 G Protein-coupled receptors in mammalian host cells. Protein Expression and Purification
Journal Article
82 (4), pp. 291 - 294 (2006)
Monitoring Redox-Dependent Contribution of Lipids in Fourier Tranform Infrared Difference Spectra of Complex I from Escherichia coli. Biopolymers Book Chapter (2)
2006
Book Chapter
Das Pichia pastoris Expressionssystem. In: Gentechnische Methoden, Eine Sammlung von Arbeitsanleitungen für das molekularbiologische Labor, 4 Ed., pp. 335 - 352 (Ed. Jansohn, M.). Spektrum Akademischer Verlag, München, Germany (2006)
Book Chapter
Expression of membrane proteins in yeasts. In: Structural Genomics on Membrane Proteins, pp. 115 - 152 (Ed. Lundstrom, K. H.). Taylor & Francis, Boca Raton, FL, USA (2006)
Thesis - PhD (6)
2006
Thesis - PhD
Production of the human adenosine A2A receptor in Pichia pastoris, its solubilization and purification, and the selection of a specific single-chain Fv fragment by phage display. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Enhancement of the Production of Functional G Protein-Coupled Receptors in the yeast Pichia pastoris and Purification of the Rat Neurokinin 2 Receptor. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Heterologous Production, Characterization and Isolation of Selected G Protein-Coupled Receptors for Structural Studies. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Structure of NhaA, a Na+/H+ antiporter from Escherichia coli and insights into mechanism of action and regulation by pH. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
The Interacting of the Cytochrome bc1 Complex with its Substrate Cytochrome c: High Resolution Structure and Implications for Transient Binding. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Heterologe Expression des humanen β2-adrenergen Rezeptors im Semliki Forest Virus-Expressionssystem. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - Diploma (2)
2006
Thesis - Diploma
Isolierung und Charakterisierung von rekombinanten NCS -Transportern in Escherichia coli. Diploma, Johannes Gutenberg-Universität, Mainz (2006)
Thesis - Diploma
Produktion der C4-Dicarboxylat-Transporter DcuA, DcuB, DcuC und "Transporter" aus Salmonella typhimurium in Escherichia coli. Diploma, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2006)