Thesis - PhD (387)
2016
Thesis - PhD
Structural and functional characterisation of peptide-ligand G protein coupled receptors – Examples from the chemoattractant cluster. Dissertation, 140 pp., Goethe Universität - Fachbereich Biochemie, Frankfurt am Main (2016)
Thesis - PhD
Structural characterization of stressosome complexes by single-particle cryo-electron microscopy. Dissertation, Goethe-Universität, Frankfurt am Main (2016)
Thesis - PhD
Structural and Functional Characterization of NorM_PS – a multidrug and toxic compound extrusion (MATE) transporter from Pseudomonas stutzeri. Dissertation, 147 pp., Tianjin University, Tianjin Province, China (2016)
Thesis - PhD
Dynamics in stress-regulated betaine transport and role of pathogen-relevant choline transport. Dissertation, Goethe-Universität, Frankfurt am Main (2016)
Thesis - PhD
Single-particle cryo-EM structures of oligomeric membrane protein complexes. Dissertation, Goethe-Universität, Frankfurt am Main (2016)
2015
Thesis - PhD
Heterologous production, purification and structural characterization of the SLC26A/SulP family of multi-functional anion transporters/exchangers from Salmonella typhimurium, Methanosarcina acetivorans and Aquifex aeolicus. Dissertation, 157 pp., Fachbereich Biochemie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2015)
Thesis - PhD
Towards a molecular mechanism of ectoine transport. Dissertation, Goethe-Universität, Frankfurt am Main (2015)
Thesis - PhD
Insights into the mechanism of substrate/product antiport by CaiT. Dissertation, Goethe-Universität, Frankfurt am Main (2015)
Thesis - PhD
Computational study of transport mechanism in LeuT fold transporters. Dissertation, 187 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität, Frankfurt am Main (2015)
2014
Thesis - PhD
Structural and functional characterization of the Na+/H+antiporter MjNhap1. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Insights into the functional and regulatory mechanisms of the osmoregulated Na+/glycine betaine symporter BetP from Corynebacterium glutamicum: A structural and computational study. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Structural and functional characterization of the rotor rings from a Bacillus and a Mycobacterium F-type ATP synthase. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Development, implementation and practical aspects of phase plates in electron cryo-microscopy. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Characterization of the two isoforms of cbb3-type cytochrome c oxidase from Pseudomonoas stutzeri ZoBell. Dissertation, 224 pp., Fachbereich 14, Biochemie, Chemie und Pharmazie der Johann Wolfgang Goethe Universität, Frankfurt am Main (2014)
Thesis - PhD
Three-dimensional crystallization of the sodium-proton antiporter NhaP1 from Methanocaldococcus jannaschii. Dissertation, Goethe university, Frankfurt am Main (2014)
Thesis - PhD
Biochemical and structural analysis of F-type ATP synthases and its subcomplexes. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Na+-coupled betaine symporters involved in osmotic stress response in prokaryotes and eukaryotes. Dissertation, Johannes Gutenberg-Universität, Mainz (2014)
Thesis - PhD
Structure and function of channelrhodopsin-2 by cryo electron crystallography. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Electron cryo-tomography of bioenergetic membranes. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Mycobacterium tuberculosis type-I fatty acid synthase: Structure and conformational variability of a protein complex by single-particle electron cryo-microscopy. Dissertation, Goethe-Universität, Frankfurt (2014)
Thesis - PhD
Investigation of electroneutral M. jannaschii NhaP1 and electrogenic H. pylori NhaA: A common transport mechanism for CPA1 and CPA2 Na+/H+ antiporters. Dissertation, Goethe Universität, Frankfurt (2014)
Thesis - PhD
Biophysikalische Analyse des eukaryotischen Proteorhodopsins ORI aus Oxyrrhis marina. Dissertation, 141 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität Frankfurt, Deutschland, Frankfurt am Main (2014)
Thesis - PhD
Heterologous Production, Isolation and Characterisation of MOP superfamily transporters from Pyrococcus furiosus, Aquifex aeolicus and Salmonella typhimurium. Dissertation, 218 pp., Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Selektion und Charakterisierung funktioneller Channelrhodopsin-2-Mutanten zur Studie von lichtinduzierten Konformationsänderungen. Dissertation, 137 pp., Fachbereich Biochemie, Goethe-Universität, Frankfurt am Main (2014)
2013
Thesis - PhD
Computational studies of lipid antigen recognition, exchange, and presentation by the CD1 protein family. Dissertation, Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
Thesis - PhD
Evaluierung der zellfreien Produktion sekundär aktiver Transporter für die Proteinkristallisation. Dissertation, 156 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main (2013)
Thesis - PhD
Heterologous Production, Isolation and Characterisation of Selected Secondary Active Transporters from the APC, AEC, CaCA, CDF, DASS and ESS families. Dissertation, 209 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
Thesis - PhD
Computational studies of F-type ATP synthases. Dissertation, 107 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
Thesis - PhD
Struktur und Funktionsweise des Molybdänspeicherproteins aus Azotobacter vinelandii. Dissertation, 176 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
Thesis - PhD
Etablierung eukaryotischer zellfreier Expressionssysteme für die Synthase humaner Membranproteine. Dissertation, 264 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
Thesis - PhD
Structural Characterizations of Two Tetrahydromethanopterin Binding Enzymes from Methanogenic Archaea. Dissertation, 105 pp., Goethe-Universität, Fachbereich Biowissenschaften, Frankfurt am Main (2013)
Thesis - PhD
Strukturelle Grundlagen des Coenzym A vermittelten Aromatenabbaus. Dissertation, 132 pp., Goethe-Universität, Fachbereich Biowissenschaften, Frankfurt am Main, Germany (2013)
Thesis - PhD
Three-dimensional crystallization and biochemical characterization of a neurotransmitter sodium symporter homologue from Methanocaldococcus jannaschii. Dissertation, Goethe-Universität, Frankfurt am Main (2013)
Thesis - PhD
Function of plant photosystem II subunits in photoprotection. Dissertation, Goethe-Universität, Frankfurt am Main (2013)
Thesis - PhD
Characterization of Aquifex aeolicus F1F0 ATP synthase and its heterologous production in Escherichia coli. Dissertation, 170 pp., Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2013)
2012
Thesis - PhD
Comparison of the Cytochrome c Oxidase inherent Catalase Side-Reaction from Paracoccus denitrificans in the wild type and recombinant form. Dissertation, Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2012)
Thesis - PhD
Biochemical and structural investigations on the architecture of the Fo complex from Ilyobacter tartaricus ATP synthase. Dissertation, Goethe-Universität, Frankfurt am Main (2012)
Thesis - PhD
Structural and functional studies on the osmoregulated trimeric Na+/betaine symporter BetP from Corynebacterium glutamicum. Dissertation, Goethe University, Frankfurt am Main (2012)
Thesis - PhD
Transportmechanismus und pH-Regulationsmechanismus des Natrium/Protonen Antiporters NhaA von Escherichia coli. Dissertation, Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2012)
Thesis - PhD
Structural and functional characterization of Aquifex aeolicus cytochrome oxidase and its supercomplex. Dissertation, Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2012)
Thesis - PhD
Computational Studies of Glutamate Transporters. Dissertation, Goethe-Universität, Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main, Germany (2012)
Thesis - PhD
Functional and Structural Membrane Proteomics using Aquifex aeolicus. Dissertation, Goethe University Frankfurt, Frankfurt am Main, Germany (2012)
2011
Thesis - PhD
From static difference to time-resolved spectroscopy of coupled electron and proton transfer in the quinol:fumarate reductase of Wolinella succinogenes. Dissertation, Goethe University Frankfurt, Frankfurt am Main, Germany (2011)
Thesis - PhD
Selektion von Bindeproteinen gegen den humanen ß2-adrenergen Rezeptor mittels ribosome display sowie Charakterisierung dieses GPCRs. Dissertation, Goethe University Frankfurt, Frankfurt am Main, Germany (2011)
Thesis - PhD
Strukturelle und funktionelle Charakterisierung ausgewählter Membranproteine. Dissertation, Goethe-Universität, Frankfurt am Main (2011)
Thesis - PhD
Essentielle Schritte im Energiestoffwechsel von Archaeen: Heterodisulfid-Reduktase und dissimilatorische Sulfit-Reduktase. Dissertation, Goethe-University Frankfurt, Frankfurt am Main, Germany (2011)
Thesis - PhD
Structural basis of Na+-independent and cooperative transport in the L-carnitine/γ-butyrobetaine antiporter CaiT. Dissertation, Goethe-University, Frankfurt am Main (2011)
Thesis - PhD
Strukturelle Untersuchungen am Superkomplex I1III2IV1 der Atmungskette mittels Kryoelektronenmikroskopie. Dissertation, Goethe Universität, Frankfurt am Main (2011)
2010
Thesis - PhD
Elektrophysiologische Untersuchung der Spannungsabhängigkeit und Kinetik der lichtaktivierten Leitfähigkeit von Channelrhodopsin-2. Dissertation, Goethe-Universität, Frankfurt am Main (2010)
Thesis - PhD
Functional and Structural Characterization of Aquifex aeolicus sulfide:quinone oxidoreductase. Dissertation, Goethe University, Frankfurt am Main, Germany (2010)
Thesis - PhD
Biochemical, Structural and Functional Characterization of Diheme-Containing Succinate:Quinone Reductase (SQR) from Bacillus licheniformis. Dissertation, Goethe University, Frankfurt am Main, Germany (2010)
Thesis - PhD
Elektrophysiologische Charakterisierung des lysosomalen Cl-/H+-Antiporters ClC-7 mit Hilfe der SSM-Technik. Dissertation, Goethe University, Frankfurt am Main, Germany (2010)
Thesis - PhD
Thermodynamic and kinetic characterisation of the interaction between mitochondrial cytochrome bc1 complex and cytochrome c and implications for transient binding and electron transfer. Dissertation, Goethe University, Frankfurt am Main, Germany (2010)
Thesis - PhD
High-resolution cryo-electron microscopy study of structure and dynamics of yeast fatty acid synthase by single particle analysis. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2010)
Thesis - PhD
Heterogolous Production and Characterization of Selected Secondary Active Transporters from the CDF, KUP, MOP, FNT, RhtB and SulP Families. Dissertation, 126 pp., Goethe University, Frankfurt am Main, Germany (2010)
Thesis - PhD
Biophysikalische Charakterisierung von endogenen Ionenkanälen (P2X7, TRPV) in humanen Mastzellen. Dissertation, 251 pp., Fachbereich Physik, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2010)
2009
Thesis - PhD
Structure and Function of the osmoregulated ectoine transporter TeaABC, a TRAP transporter from Halomonas elongata. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Single Channel Properties of Channelrhodopsin-2 Determined by Stationary Noise Analysis. Dissertation, 125 pp., Fachbereich Biochemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Electrophysiological Characterization of Cation Coupled Symporters and Investigation of Physicochemical Surface Processes with a Solid-Supported Membrane. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2009)
Thesis - PhD
Structural rearrangements and subunit interactions in P2X receptors. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2009)
Thesis - PhD
Untersuchungen zur Regulation von rP2X2 Rezeptoren durch Phosphoinositide mittels einer heterolog exprimierten, intrazellulären spannungsgesteuerten Phosphoinositid-Phosphatase aus Ciona intestinalis. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2009)
Thesis - PhD
X-Ray Structure of the Na+-coupled Glycine-Betaine Symporter BetP from Corynebacterium glutamicum. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Bindung des C1-Carriers Tetrahydromethanopterin und seiner Derivate an Enzyme des Energiestoffwechselweges Methanbildender Archaeen. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2009)
Thesis - PhD
Three-dimensional structure of the Na+/H+ antiporter from Methanococcus jannaschii. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Mechanisms of energy transfer and conversion in plant Light-Harvesting Complex II. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Functional and Structural Studies on the Atmungsferment Cytochrome c Oxidase from Paracoccus denitrificans. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2009)
Thesis - PhD
Substrate-Dependent Effects on the Conformational Equilibrium of the Na+, K+-ATPase monitored by VCF. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2009)
Thesis - PhD
Die Fakir-Methode - dielektrophoretische Zellattraktion und intrazelluläre Messung von Ionenkanälen mit Nanometallelektroden. Dissertation, Johann Wolgang Goethe-Universität, Frankfurt am Main (2009)
2008
Thesis - PhD
Three-dimensional structure of the glycine-betaine transporter BetP by cryo electron crystallography. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Purification and Characterisation of the Respiratory Supercomplex III/IV from Corynebacterium glutamicum and Phospholipid Analysis of Membrane Proteins. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Reinigung und Charakterisierung von monovalenten Kation/Proton-Antiportern. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Overexpression, Biochemical Characterization and Crystallization of Chitin Synthase 2 from Saccharomyces cerevisae. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Electron Tomography of Membrane Proteins. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Development and Application of In-Focus Phase Contrast TEM for Materials and Life Sciences. Dissertation, Ruprecht-Karls-Universität, Heidelberg (2008)
Thesis - PhD
Increases in Intracellular Calcium Triggered by Channelrhodopsin-2 Potentiate the Response of Metabotropic Glutamate Receptor mGluR7. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
Thesis - PhD
Funktionelle Expression von Channelrhodopsin 2 (ChR2) in der methylotrophen Hefe Pichia pastoris und biophysikalische Charakterisierung. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2008)
2007
Thesis - PhD
Functional and Structural Membrane Proteomics using Aquifex aeolicus. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Studies on the protein translocation in Escherichia coli: anaysis of the integral membrane proteins SecYEG and YidC employing biochemical and crystallographic methods. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2007)
Thesis - PhD
Theoretical Investigation of Transmembrane Electron Coupled Proton Transfer in Quinol: Fumarate Reductase from Wolinella succinogenes. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Heterologous Production and Characterization of Two Distinct Di-Heme Containing Membrane Integral Cytochrome b561 Enzymes from Arabidopsis thaliana. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
The human GPCR Nicotinic Acid Receptor 1: Heterologous Overproduction in Pichia pastoris and the Reconstitution of its complex with β-Arrestin 1 in vivo and in vitro. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Structural Genomics on Prokaryotic Membrane Proteins. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Purification and Characterization of Heterologously Produced Cannabinoid Receptor 1 and G proteins. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Generation of recombinant antibodies against membrane proteins by phage display. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Production, Biochemical Characterization and Preliminary Structural Studies of Human Endothelin B Receptor in its Ligand-bound State. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Development of a novel approach and a new expression system for the production and crystallization of human G protein-coupled receptors. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Structural studies on terminal oxidases and an electron donor to a terminal oxidase. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Establishment of an Escherichia coli cell-free expression system for the large scale production of selected membrane proteins. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Molekularbiologische und biochemische Charakterisierung der "Succinat-Dehydrogenase" aus Wolinella succinogenes. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2007)
Thesis - PhD
Expression and Characterization of P-type ATPases for Structural Studies. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2007)
Thesis - PhD
Untersuchung der Protonenbewegung während des O➝E Schrittes im katalytischen Zyklus der Cytochrom-c-Oxidase von Paracoccus denitrificans. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2007)
Thesis - PhD
Investigations on subunit-specific assembly and structure-function studies of the voltage sensor in KCNQ potassium channel. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2007)
Thesis - PhD
Festkörperunterstützte Membranen zur Untersuchung von elektrogenen Transportvorgängen und deren Potential für die Hochdurchsatz-Wirkstoffsuche. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2007)
2006
Thesis - PhD
Kinetik und molekulare Mechanismen des Plasmamembran Glutamattransports. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2006)
Thesis - PhD
Production of the human adenosine A2A receptor in Pichia pastoris, its solubilization and purification, and the selection of a specific single-chain Fv fragment by phage display. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Kinetik des Protonen gekoppelten Elektronentransfers in Enzymkomplexen der Atmungskette. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2006)
Thesis - PhD
Enhancement of the Production of Functional G Protein-Coupled Receptors in the yeast Pichia pastoris and Purification of the Rat Neurokinin 2 Receptor. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)
Thesis - PhD
Electrophysiological and spectroscopical characterization of the Na,K-ATPase. Dissertation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2006)
Thesis - PhD
Heterologous Production, Characterization and Isolation of Selected G Protein-Coupled Receptors for Structural Studies. Dissertation, Johann Wolfgang Goethe-University, Frankfurt am Main (2006)