Publications of the Max Planck Institute of Biophysics 1947 – present

Journal Article (82)

2021

Journal Article

Ellinghaus, T. L.; Marcellino, T.; Srinivasan, V.; Lill, R.; Kühlbrandt, W.: Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle. Science Advances 7 (52), eabk2392 (2021)

MPG.PuRe

DOI

Journal Article

Köfinger, J.; Hummer, G.: Empirical optimization of molecular simulation force fields by Bayesian inference. The European Physical Journal B: Condensend Matter Physics 94 (12), 245 (2021)

MPG.PuRe

DOI

Full

Journal Article

Luciano, V.; Proschak, E.; Langer, J. D.; Knapp, S.; Heering, J.; Marschalek, R.: Closantel is an allosteric inhibitor of human Taspase1. iScience 24 (12), e103524 (2021)

MPG.PuRe

DOI

Journal Article

Grund, T. N.; Radloff, M.; Wu, D.; Goojani, H. G.; Witte, L. F.; Jösting, W.; Buschmann, S.; Müller, H.; Elamri, I.; Welsch, S. et al.; Schwalbe, H.; Michel, H.; Bald, D.; Safarian, S.: Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 118 (50), e2114013118 (2021)

MPG.PuRe

DOI

Journal Article

Konia, E.; Chatzicharalampous, K.; Drakonaki, A.; Münke, C.; Ermler, U.; Tsiotis, G.; Pavlidis, I. V.: Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications 57 (96), pp. 12948 - 12951 (2021)

MPG.PuRe

DOI

Journal Article

Radloff, M.; Elamri, I.; Grund, T. N.; Witte, L. F.; Hohmann, K. F.; Nakagaki, S.; Goojani , H. G.; Nasiri, H.; Miyoshi , H.; Bald, D. et al.; Xie, H.; Sakamoto, J.; Schwalbe, H.; Safarian, S.: Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases. Scientific Reports 11 (1), e23852 (2021)

MPG.PuRe

DOI

Journal Article

Zimmerli, C. E.; Allegretti, M.; Rantos, V.; Goetz, S. K.; Obarska-Kosinska, A.; Zagoriy, I.; Halavatyi, A.; Hummer, G.; Mahamid, J.; Kosinski, J. et al.; Beck, M.: Nuclear pores dilate and constrict in cellulo. Science 374 (6573), eabd9776 (2021)

MPG.PuRe

DOI

Full

Journal Article

Centola, M.; van Pee, K.; Betz, H.; Yildiz, Ö.: Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases. Nature Communications 12 (1), 6982 (2021)

MPG.PuRe

DOI

Journal Article

Kolbe, F.; Safarian, S.; Piórek, Ż.; Welsch, S.; Müller, H.; Michel, H.: Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications 12, 6903 (2021)

MPG.PuRe

DOI

Journal Article

Sim, S. I.; von Bülow, S.; Hummer, G.; Park, E.: Structural basis of polyamine transport by human ATP13A2 (PARK9). Molecular Cell 81, pp. 4635 - 4649 (2021)

MPG.PuRe

DOI

Journal Article

Kung, J.; Meier, A.-K.; Willistein, M.; Weidenweber, S.; Demmer, U.; Ermler, U.; Boll, M.: Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem 22 (22), pp. 3172 - 3177 (2021)

MPG.PuRe

DOI

Journal Article

Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)

MPG.PuRe

DOI

Journal Article

Parey, K.; Lasham, J.; Mills, D. J.; Djurabekova, A.; Haapanen, O.; Yoga, E. G.; Xie, H.; Kühlbrandt, W.; Sharma, V.; Vonck, J. et al.; Zickermann, V.: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances 7 (46), eabj3221 (2021)

MPG.PuRe

DOI

Journal Article

Heit, S.; Geurts, M. M. G.; Murphy, B. J.; Corey, R. A.; Mills, D. J.; Kühlbrandt, W.; Bublitz, M.: Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances 7 (46), eabj5255 (2021)

MPG.PuRe

DOI

Journal Article

Hollenstein, D. M.; Gérecová, G.; Romanov, N.; Ferrari, J.; Veis, J.; Janschitz, M.; Beyer, R.; Schüller, C.; Ogris, E.; Hartl, M. et al.; Ammerer, G.; Reiter, W.: A phosphatase-centric mechanism drives stress signaling response. EMBO Reports 22 (11), e52476 (2021)

MPG.PuRe

DOI

Full

Journal Article

Rocha-Roa, C.; Orjuela, J. D.; Leidy, C.; Cossio, P.; Aponte-Santamaría, C.: Cardiolipin prevents pore formation in phosphatidylglycerol bacterial membrane models. FEBS Letters 595 (21), pp. 2701 - 2714 (2021)

MPG.PuRe

DOI

Journal Article

Bieber, A.; Capitanio, C.; Wilfling, F.; Plitzko, J.; Erdmann, P. S.: Sample Preparation by 3D-Correlative Focused Ion Beam Milling for High-Resolution Cryo-Electron Tomography. Journal of Visualized Experiments (176), e62886 (2021)

MPG.PuRe

DOI

Full

Journal Article

Fusco, C. M.; Desch, K.; Dörrbaum, A. R.; Wang, M.; Staab, A.; Chan, I. C. W.; Vail, E.; Villeri, V.; Langer, J. D.; Schuman, E. M.: Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins. Nature Communications 12 (1), 6127 (2021)

MPG.PuRe

DOI

Journal Article

Klaus, M.; Rossini, E.; Linden, A.; Paithankar, K. S.; Zeug, M.; Ignatova, Z.; Urlaub, H.; Khosla, C.; Köfinger, J.; Hummer, G. et al.; Grininger, M.: Solution Structure and Conformational Flexibility of a Polyketide Synthase Module. JACS Au 1 (12), pp. 2162 - 2171 (2021)

MPG.PuRe

DOI

Full

Journal Article

Müller, D. J.; Dumitru, A. C.; Lo Giudice, C.; Gaub, H. E.; Hinterdorfer, P.; Hummer, G.; De Yoreo, J. J.; Dufrêne, Y. F.; Alsteens, D.: Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems. Chemical Reviews 121 (19), pp. 11701 - 11725 (2021)

MPG.PuRe

DOI

Journal Article

Hulleman, C. N.; Thorsen, R. Ø.; Kim, E.; Dekker, C.; Stallinga, S.; Rieger, B.: Simultaneous orientation and 3D localization microscopy with a Vortex point spread function. Nature Communications 12 (1), 5934 (2021)

MPG.PuRe

DOI

Journal Article

Weissbecker, J.; Boumrifak, C.; Breyer, M.; Wießalla, T.; Shevchenko, V.; Mager, T.; Slavov, C.; Alekseev , A.; Kovalev, K.; Gordeliy , V. et al.; Bamberg, E.; Wachtveitl, J.: The voltage dependent sidedness of the reprotonation of the retinal Schiff base determines the unique inward pumping of Xenorhodopsin. Angewandte Chemie, International Edition in English 60 (42), pp. 23010 - 23017 (2021)

MPG.PuRe

DOI

Journal Article

Mathioudaki, E.; Arvaniti, K.; Münke, C.; Drakonaki, A.; Vranakis, I.; Koutantou, M.; Psaroulaki, A.; Xie, H.; Tsiotis, G.: Expression, purification and characterization of the IcmG and IcmK proteins of the Type IVB secretion system from Coxiella burnetii. Protein Expression and Purification 186, 105905 (2021)

MPG.PuRe

DOI

Journal Article

Erdbrügger, P.; Wilfling, F.: p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 118 (37), e2113647118 (2021)

MPG.PuRe

DOI

Journal Article

Erdmann, P. S.; Hou, Z.; Klumpe, S.; Khavnekar, S.; Beck, F.; Wilfling, F.; Plitzko, J. M.; Baumeister, W.: In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications 12 (1), 5364 (2021)

MPG.PuRe

DOI

Journal Article

Reggio, A.; Buonomo, V.; Berkane, R.; Bhaskara, R.; Tellechea, M.; Peluso, I.; Polishchuk, E.; Di Lorenzo, G.; Cirillov, C.; Esposito, M. et al.; Hussain, A.; Huebner, A. K.; Hübner, C. A.; Settembre, C.; Hummer, G.; Grumati, P.; Stolz, A.: Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. EMBO Reports 22 (9), e52289 (2021)

MPG.PuRe

DOI

Journal Article

Watanabe, T.; Pfeil-Gardiner, O.; Kahnt, J.; Koch, J.; Shima, S.; Murphy, B. J.: Three-megadalton complex of methanogenic electron-bifurcating and CO₂-fixing enzymes. Science 373 (6559), pp. 1151 - 1156 (2021)

MPG.PuRe

DOI

Journal Article

Safarian, S.; Opel-Reading, H. K.; Wu, D.; Mehdipour, A. R.; Hards, K.; Harold, L. H.; Radloff, M.; Stewart, I.; Welsch, S.; Hummer, G. et al.; Cook, G. M.; Krause, K. L.; Michel, H.: The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications 12 (1), 5236 (2021)

MPG.PuRe

DOI

Journal Article

Chicano, T. M.; Dietrich, L.; de Almeida, N. M.; Akram, M.; Hartmann, E.; Leidreiter, F.; Leopoldus, D.; Mueller, M.; Sanchez, R. M.; Nuijten, G. H. L. et al.; Reimann, J.; Seifert, K.-A.; Schlichting, I.; van Niftrik, L.; Jetten, M. S. M.; Dietl, A.; Kartal, B.; Parey, K.; Barends, T. R. M.: Structural and functional characterization of the intracellular filament-forming nitrite oxidoreductase multiprotein complex. Nature Microbiology 6 (9), pp. 1129 - 1139 (2021)

MPG.PuRe

DOI

Journal Article

Falkner, S.; Schwierz, N.: Kinetic pathways of water exchange in the first hydration shell of magnesium: Influence of water model and ionic force field. The Journal of Chemical Physics 155 (8), 084503 (2021)

MPG.PuRe

DOI

Journal Article

Desch, K.; Langer, J. D.; Schuman, E. M.: Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling. Cell Reports 36 (8), 109583 (2021)

MPG.PuRe

DOI

Journal Article

Sabinina, V. J.; Hossain, M. J.; Hériché, J.-K.; Hoess, P.; Nijmeijer, B.; Mosalaganti, S.; Kueblbeck, M.; Callegari, A.; Szymborska, A.; Beck, M. et al.; Ries, J.; Ellenberg, J.: Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex. Molecular Biology of the Cell 32 (17), pp. 1523 - 1533 (2021)

MPG.PuRe

DOI

Full

Journal Article

Väth, K.; Mattes, C.; Reinhard, J.; Covino, R.; Stumpf, H.; Hummer, G.; Ernst, R.: Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1. The Journal of Cell Biology 220 (8), e202011078 (2021)

MPG.PuRe

DOI

Journal Article

Mukherjee, R.; Bhattacharya, A.; Bojkova, D.; Mehdipour, A. R.; Shin, D.; Khan, K. S.; Hei-Yin Cheung, H.; Wong, K.-B.; Ng, W.; Cinatl, J. et al.; Geurink, P. P.; van der Heden van Noort, G. J.; Rajalingam, K.; Ciesek, S.; Hummer, G.; Dikic, I.: Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. The Journal of Biological Chemistry 297 (2), 100925 (2021)

MPG.PuRe

DOI

Journal Article

Nikolaev, A.; Safarian, S.; Thesseling, A.; Wohlwend, D.; Friedrich, T.; Michel, H.; Kusumoto, T.; Sakamoto, J.; Melin, F.; Hellwig, P.: Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics 1862 (8), e148436 (2021)

MPG.PuRe

DOI

Journal Article

Kanavaki, I.; Drakonaki, A.; Geladas, E. D.; Spyros, A.; Xie, H.; Tsiotis, G.: Polyhydroxyalkanoate (PHA) Production in Pseudomonas sp. phDV1 Strain Grown on Phenol as Carbon Sources. Microorganisms 9 (8), 1636 (2021)

MPG.PuRe

DOI

Journal Article

Schumacher, M.; Klare, J. P.; Bamann, C.; Steinhoff, H.-J.: DEER Spectroscopy of Channelrhodopsin-2 Helix B Movements in Trapped Photocycle Intermediates. Applied Magnetic Resonance (2021)

MPG.PuRe

DOI

Full

Journal Article

Schaefer, S. L.; Jung, H.; Hummer, G.: Binding of SARS-CoV-2 Fusion Peptide to Host Endosome and Plasma Membrane. The Journal of Physical Chemistry B 125 (28), pp. 7732 - 7741 (2021)

MPG.PuRe

DOI

Journal Article

Becker-Baldus, J.; Leeder, A.; Brown, L. J.; Brown, R. C. D.; Bamann, C.; Glaubitz, C.: The Desensitized Channelrhodopsin-2 Photointermediate Contains 13 -cis, 15 -syn Retinal Schiff Base. Angewandte Chemie, International Edition in English 60 (30), pp. 16442 - 16447 (2021)

MPG.PuRe

DOI

Journal Article

Armstrong, L. A.; Lange, S. M.; Dee Cesare, V.; Matthews, S. P.; Nirujogi, R. S.; Cole, I.; Hope, A.; Cunningham, F.; Toth, R.; Mukherjee, R. et al.; Bojkova, D.; Gruber, F.; Gray, D.; Wyatt, P. G.; Cinatl, J.; Đikić, I.; Davies, P.; Kulathu, Y.: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One 16 (7), e0253364 (2021)

MPG.PuRe

DOI

Journal Article

Kannt, A.; Đikić, I.: Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation. Cell Chemical Biology 28 (7), pp. 1014 - 1031 (2021)

MPG.PuRe

DOI

Journal Article

Giraldo-Barreto, J.; Ortiz, S.; Thiede, E. H.; Palacio-Rodriguez, K.; Carpenter, B.; Barnett, A. H.; Cossio, P.: A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments. Scientific Reports 11 (1), 13657 (2021)

MPG.PuRe

DOI

Journal Article

Zabelskii, D.; Dmitrieva, N.; Volkov, O.; Shevchenko, V.; Kovalev, K.; Balandin, T.; Soloviov, D.; Astashkin, R.; Zinovev, E.; Alekseev, A. et al.; Round, E.; Polovinkin, V.; Chizhov, I.; Rogachev, A.; Okhrimenko, I.; Borshchevskiy, V.; Chupin, V.; Büldt, G.; Yutin, N.; Bamberg, E.; Koonin, E.; Gordeliy, V.: Structure-based insights into evolution of rhodopsins. Communications Biology 4 (1), 821 (2021)

MPG.PuRe

DOI

Journal Article

Feyh, R.; Waeber, N. B.; Prinz, S.; Giammarinaro, P. I.; Bange, G.; Hochberg, G.; Hartmann, R. K.; Altegoer, F.: Structure and mechanistic features of the prokaryotic minimal RNase P. eLife 10, e70160 (2021)

MPG.PuRe

DOI

Journal Article

Bullerjahn, J. T.; Hummer, G.: Maximum likelihood estimates of diffusion coefficients from single-particle tracking experiments. The Journal of Chemical Physics 154 (23), 234105 (2021)

MPG.PuRe

DOI

Journal Article

Zhu, G.; Zeng, H.; Zhang, S.; Juli, J.; Tai, L.; Zhang, D.; Pang , X.; Zhang, Y.; Lam, S. M.; Zhu, Y. et al.; Peng, G.; Michel, H.; Sun, F.: The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English 60 (24), pp. 13323 - 13330 (2021)

MPG.PuRe

DOI

Journal Article

Dijkman, P. M.; Marzluf, T.; Zhang, Y.; Chang, S.-Y. S.; Helm, D.; Lanzer, M.; Bujard, H.; Kudryashev, M.: Structure of the merozoite surface protein 1 from Plasmodium falciparum. Science Advances 7 (23), eabg0465 (2021)

MPG.PuRe

DOI

Journal Article

Klusch, N.; Senkler, J.; Yildiz, Ö.; Kühlbrandt, W.; Braun, H.-P.: A ferredoxin bridge connects the two arms of plant mitochondrial complex I. The Plant Cell 33 (6), pp. 2072 - 2091 (2021)

MPG.PuRe

DOI

Journal Article

Mehdipour, A. R.; Hummer, G.: Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 118 (19), e2100425118 (2021)

MPG.PuRe

DOI

Journal Article

Ho, N. T.; Siggel, M.; Camacho, K. V.; Bhaskara, R.; Hicks, J. M.; Yao, Y.-C.; Zhang, Y.; Köfinger, J.; Hummer, G.; Noy, A.: Membrane fusion and drug delivery with carbon nanotube porins. Proceedings of the National Academy of Sciences of the United States of America 118 (19), e2016974118 (2021)

MPG.PuRe

DOI

Full

Journal Article

Cruz-León, S.; Grotz, K. K.; Schwierz, N.: Extended magnesium and calcium force field parameters for accurate ion–nucleic acid interactions in biomolecular simulations. The Journal of Chemical Physics 154 (17), 171102 (2021)

MPG.PuRe

DOI

Full

Journal Article

Staritzbichler, R.; Sarti, E.; Yaklich, E.; Aleksandrova, A.; Stamm, M.; Khafizov, K.; Forrest, L. R.: Refining pairwise sequence alignments of membrane proteins by the incorporation of anchors. plos one 16 (4), e0239881 (2021)

MPG.PuRe

DOI

Journal Article

Floris, D.; Kühlbrandt, W.: Molecular landscape of etioplast inner membranes in higher plants. Nature Plants 7 (4), pp. 514 - 523 (2021)

MPG.PuRe

DOI

Journal Article

Kayastha, K.; Vitt, S.; Buckel, W.; Ermler, U.: Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics 701, 108796 (2021)

MPG.PuRe

DOI

Journal Article

Grotz, K. K.; Cruz-León, S.; Schwierz, N.: Optimized Magnesium Force Field Parameters for Biomolecular Simulations with Accurate Solvation, Ion-Binding, and Water-Exchange Properties. Journal of Chemical Theory and Computation 17 (4), pp. 2530 - 2540 (2021)

MPG.PuRe

DOI

Full

Journal Article

Nome, R. A.; Cossio, P.; Z, Y.: Editorial: Integrating Timescales From Molecules Up. Frontiers in Chemistry 9, 680533 (2021)

MPG.PuRe

DOI

Journal Article

Zabret, J.; Bohn, S.; Schuller, S. K.; Arnolds, O.; Möller, M.; Meier-Credo, J.; Liauw, P.; Chan, A.; Tajkhorshid, E.; Langer, J. D. et al.; Stoll, R.; Krieger-Liszkay, A.; Engel, B. D.; Rudack , T.; Schuller, J. M.; Nowaczyk , M. M.: Structural insights into photosystem II assembly. Nature Plants 7, pp. 524 - 538 (2021)

MPG.PuRe

DOI

Journal Article

Appel, L.; Willistein, M.; Dahl, C.; Ermler, U.; Boll, M.: Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics 1862 (4), 148379 (2021)

MPG.PuRe

DOI

Journal Article

Gubas, A.; Karantanou, C.; Popovic, D.; Tascher, G.; Hoffmann, M. E.; Platzek, A.; Dawe, N.; Dikic, I.; Krause, D. S.; McEwan, D. G.: The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways. FEBS Letters 595 (7), pp. 864 - 880 (2021)

MPG.PuRe

DOI

Journal Article

Sikora, M.; von Bülow, S.; Blanc, F. E. C.; Gecht, M.; Covino, R.; Hummer, G.: Computational epitope map of SARS-CoV-2 spike protein. PLoS Computational Biology 17 (4), e1008790 (2021)

MPG.PuRe

DOI

Full

Journal Article

Ochoa, R.; Laskowski, R. A.; Thornton, J. M.; Cossio, P.: Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders. Frontiers in Molecular Biosciences 8, 636562 (2021)

MPG.PuRe

DOI

Journal Article

Ochoa, R.; Cossio, P.: PepFun: Open Source Protocols for Peptide-Related Computational Analysis. Molecules 26 (6), 1664 (2021)

MPG.PuRe

DOI

Journal Article

Jakdetchai, O.; Eberhardt, P.; Asido, M.; Kaur, J.; Kriebel, C. N.; Mao, J.; Leeder, A. J.; Brown, L. J.; Brown, R. C. D.; Becker-Baldus, J. et al.; Bamann, C.; Wachtveitl, J.; Glaubitz, C.: Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-enhanced solid-state NMR. Science Advances 7 (11), eabf4213 (2021)

MPG.PuRe

DOI

Journal Article

D'Imprima, E.; Kühlbrandt, W.: Current limitations to high-resolution structure determination by single-particle cryoEM. Quarterly Reviews of Biophysics 54, e4 (2021)

MPG.PuRe

DOI

Journal Article

Berger, C.; Ravelli, R. B. G.; López-Iglesias, C.; Kudryashev, M.; Diepold, A.; Peters, P. J.: Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography. Journal of Structural Biology 213 (1), 107701 (2021)

MPG.PuRe

DOI

Journal Article

Ernst, C.; Kayastha, K.; Koch , T.; Venceslau, S. S.; Pereira, I. A.C.; Demmer, U.; Ermler, U.; Dahl, C.: Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal 288 (5), pp. 1664 - 1678 (2021)

MPG.PuRe

DOI

Journal Article

Wieferig, J.-P.; Mills, D. J.; Kühlbrandt, W.: Devitrification reduces beam-induced movement in cryo-EM. IUCrJ 8 (Pt 2), pp. 186 - 194 (2021)

MPG.PuRe

DOI

Journal Article

Siggel, M.; Bhaskara, R.; Moesser, M. K.; Đikić, I.; Hummer, G.: FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes. The Journal of Physical Chemistry Letters 12 (7), pp. 1926 - 1931 (2021)

MPG.PuRe

DOI

Journal Article

Gorgulla, C.; Padmanabha Das, K. M.; Leigh, K. E.; Cespugli, M.; Fischer, P. D.; Wang, Z.-F.; Tesseyre, G.; Pandita, S.; Shnapir, A.; Calderaio, A. et al.; Gechev, M.; Rose, A.; Lewis, N.; Hutcheson, C.; Yaffe, E.; Luxenburg, R.; Herce, H. D.; Durmaz, V.; Halazonetis, T. D.; Fackeldey, K.; Patten, J. J.; Chuprina, A.; Dziuba, I.; Plekhova, A.; Moroz, Y.; Radchenko, D.; Tarkhanova, O.; Yavnyuk, I.; Gruber, C.; Yust, R.; Payne, D.; Näär, A. M.; Namchuk, M. N.; Davey, R. A.; Wagner, G.; Kinney, J.; Arthanari, H.: A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening. iScience 24 (2), 102021 (2021)

MPG.PuRe

DOI

Journal Article

Zila, V.; Margiotta, E.; Turoňová, B.; Müller, T. G.; Zimmerli, C. E.; Mattei, S.; Allegretti, M.; Börner, K.; Rada, J.; Müller, B. et al.; Lusic, M.; Kräusslich, H.-G.; Beck, M.: Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell 184 (4), pp. 1032 - 1046 (2021)

MPG.PuRe

DOI

Full

Journal Article

Zhang, Y.; Dijkman, P. M.; Zou, R.; Zandl-Lang, M.; Sanchez, R. M.; Eckhardt-Strelau, L.; Köfeler, H.; Vogel, H.; Yuan, S.; Kudryashev, M.: Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers. Nature Communications 12 (1), 1074 (2021)

MPG.PuRe

DOI

Journal Article

Eberhardt, P.; Slavov, C.; Sörmann, J.; Bamann, C.; Braun, M.; Wachtveitl, J.: Temperature Dependence of the Krokinobacter rhodopsin 2 Kinetics. Biophysical Journal (Annual Meeting Abstracts) 120 (3), pp. 568 - 575 (2021)

MPG.PuRe

DOI

Journal Article

Riedel, R.; Frese, N.; Yang, F.; Wortmann, M.; Dalpke, R.; Rhinow, D.; Hampp, N.; Gölzhäuser, A.: Fusion of purple membranes triggered by immobilization on carbon nanomembranes. Beilstein Journal of Nanotechnology 12, pp. 93 - 101 (2021)

MPG.PuRe

DOI

Journal Article

Benayad, Z.; von Bülow, S.; Stelzl, L. S.; Hummer, G.: Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model. Journal of Chemical Theory and Computation 17 (1), pp. 525 - 537 (2021)

MPG.PuRe

DOI

Journal Article

Tiku, V.; Kofoed, E. M.; Yan, D.; Kang, J.; Xu, M.; Reichelt, M.; Dikic, I.; Tan, M.-W.: Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Scientific Reports 11 (1), 618 (2021)

MPG.PuRe

DOI

Journal Article

Cunha, E. S.; Chen, X.; Sanz-Gaitero, M.; Mills, D. J.; Luecke, H.: Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution. Nature Communications 12 (1), 230 (2021)

MPG.PuRe

DOI

Journal Article

Mills, D. J.: Setting up and operating a cryo-EM laboratory. Quarterly Reviews of Biophysics 54, e2 (2021)

MPG.PuRe

DOI

Journal Article

Ross, A. B.; Langer, J. D.; Jovanovic, M.: Proteome Turnover in the Spotlight: Approaches, Applications, and Perspectives. Molecular and Cellular Proteomics 20, 100016 (2021)

MPG.PuRe

DOI

Journal Article

Bárcena, M.; Barnes, C. O.; Beck, M.; Bjorkman, P. J.; Canard, B.; Gao, G. F.; Gao, Y.; Hilgenfeld, R.; Hummer, G.; Patwardhan, A. et al.; Santoni, G.; Saphire, E. O.; Schaffitzel, C.; Schendel, S. L.; Smith, J. L.; Thorn, A.; Veesler, D.; Zhang, P.; Zhou, Q.: Structural biology in the fight against COVID-19. Nature Structural and Molecular Biology 28 (1), pp. 2 - 7 (2021)

MPG.PuRe

DOI

Journal Article

Klionsky, D. J.; Abdel-Aziz, A. K.; Abdelfatah, S.; Hummer, G.; 2295 other, A.: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17 (1), pp. 1 - 382 (2021)

MPG.PuRe

DOI

Journal Article

Lyratzakis, A.; Valsamidis, G.; Kanavaki, I.; Nikolaki , A.; Rupprecht, F. A.; Langer, J. D.; Tsiotis, G.: Proteomic Characterization of the Pseudomonas sp. Strain phDV1 Response to Monocyclic Aromatic Compounds. Proteomics 21 (2), e2000003 (2021)

MPG.PuRe

DOI

Journal Article

Wells, C. I.; Al-Ali, H.; Andrews, D. M.; Asquith, C. R. M.; Axtman, A. D.; Dikic, I.; Ebner, D.; Ettmayer, P.; Fischer, C.; Frederiksen, M. et al.; Futrell, R. E.; Gray, N. S.; Hatch, S. B.; Knapp, S.; Lücking, U.; Michaelides, M.; Mills, C. E.; Müller, S.; Owen, D.; Picado, A.; Saikatendu, K. S.; Schröder, M.; Stolz, A.; Tellechea, M.; Turunen, B. J.; Vilar, S.; Wang, J.; Zuercher, W. J.; Willson, T. M.; Drewry, D. H.: The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. International Journal of Molecular Sciences 22 (2), 566 (2021)

MPG.PuRe

DOI

Book Chapter (2)

2021

Book Chapter

Hussein, T.; Bamann, C.: Charge Transport by Light-Activated Rhodopsins Determined by Electrophysiological Recordings. In: Methods in Molecular Biology: Methods and Protocols - Channelrhodopsin, Vol. 2191, pp. 67 - 84. Springer Nature (2021)

MPG.PuRe

DOI

Book Chapter

Januliene, D.; Moeller, A.: Single-Particle Cryo-EM of Membrane Proteins. In: Methods in Molecular Biology: Structure and Function of Membrane Proteins, Vol. 2302, pp. 153 - 178 (Ed. Schmidt-Krey, I.). Springer (2021)

MPG.PuRe

DOI

Thesis - PhD (3)

2021

Thesis - PhD

Floris, D.: Electron cryo-tomography during the Resolution Revolution: a multi-scale study from protein denaturation to plant plastid bioenergetics. Dissertation, 158 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität, Frankfurt am Main (2021)

MPG.PuRe

Thesis - PhD

Siggel, M.: Shaping and Remodeling of Biological Membranes. Dissertation, 180 pp., Fachbereich Physik, Johann Wolfgang Goethe Universität, Frankfurt am Main (2021)

MPG.PuRe

Thesis - PhD

Heinz, M.: Molecular Simulation and Modeling of Chemically Modified Nucleic Acids. Dissertation, 174 pp., Fachbereich Biochemie, Chemie und Pharmazie, Johann Wolfgang Goethe Universität, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Habilitation (1)

2021

Thesis - Habilitation

Parey, K.: The Alpha and Omega of Biological Energy Conservation. Habilitation, 308 pp., Fach Mikrobiologie, Fachbereich Biowissenschaften, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Master (3)

2021

Thesis - Master

Finke, A. F.: Structural and functional insights about the ABC Transporter CYDDC from E.coli. Master, 91 pp., Department of Biochemistry, Chemistry and Pharmacy (FB 14), Johann Wolfgang Goethe University Frankfurt, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Master

Groh, R. R.: Structure and Function of the Bacterial ABC Transporter CydDC. Master, 61 pp., Departments of Biochemistry, Chemistry and Pharmacy, Goethe-University Frankfurt, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Master

Karabel, M.: Structural characterization of membrane-integrated enzyme complexes. Master, 49 pp., Institute für Organische Chemie und Chemische Biologie, Goethe-Universität Frankfurt, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Bachelor (4)

2021

Thesis - Bachelor

Sadowski, S.: How CHMP1b interacts with the membrane. Bachelor, 54 pp., Fachbereich Physik, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Bachelor

Müller, L.: Herstellung, Reinigung und Charakterisierung universeller Anti-Nanobody Antikörper für die strukturbiologische Untersuchung. Bachelor, 62 pp., Fachbereich Biowissenschaften, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Bachelor

Allo, P. V.: Biochemical and Structural Characterization of Secondary Active Transporters using Nanobody Library. Bachelor, 42 pp., Department of Biochemistry, Chemistry and Pharmacy, Johann Wolfgang Goethe University, Frankfurt am Main (2021)

MPG.PuRe

Thesis - Bachelor

Witte, L. F.: Development of a label free thermal shift assay to investigate the binding of small molecules to Escherichia coli bd-type oxidases. Bachelor, 68 pp., Fakultät 2 Umwelt und Naturwissenschaften, Institut für Biotechnologie, Brandenburgische Technische Universität, Cottbus-Senftenberg, Germany (2021)

MPG.PuRe