Presse- und Öffentlichkeitsarbeit

Dr. Martin Beck ist neuer Direktor am Max-Planck-Institut für Biophysik

Dr. Martin Beck, © M. Beck

15. Januar 2019

Dr. Martin Beck ist neuer Direktor am MPI für Biophysik in Frankfurt am Main

Wir freuen uns sehr, dass Dr. Martin Beck vom Europäischen Laboratorium für Molekularbiologie (EMBL) in Heidelberg den Ruf der Max-Planck-Gesellschaft zum Wissenschaftlichen Mitglied und Direktor am MPI für Biophysik angenommen hat.
Er wird die neue Abteilung Molekulare Soziologie aufbauen, die eine exzellente Ergänzung zu den jetzigen Forschungen am Institut darstellt. Martin Beck ist ein hervorragender Experte auf dem Gebiet der Kernporenkomplexe, die er durch Kombination von verschiedenen Verfahren wie Kryo-Elektronentomographie (CET), Proteomik, biochemische und massenspektroskopische Methoden untersucht.

Martin Beck promovierte im Bereich Molekulare Strukturbiologie bei Wolfgang
Baumeister, Direktor am MPI für Biochemie in Martinsried. Dabei befasste er sich mit der Struktur der Kernporen (NPC: nuclear pore complex), makromolekularen Maschinen, welche für die Kommunikation zwischen dem Zellkern und dem Zytoplasma verantwortlich sind. Deren dreidimensionale Struktur konnte mittels Kryo-Elektronentomographie rekonstruiert und unterschiedlichen funktionellen Zuständen zugeordnet werden. Nach seiner Promotion 2006 ging Martin Beck als Postdoktorand an die ETH Zürich (Eidgenössische Technische Hochschule) ins Labor von Professor Ruedi Aebersold, einem der Pioniere der Proteomforschung. Hier entwickelte er integrative Methoden zur quantitativen Analyse der makromolekularen Zusammensetzung und Architektur von Zellen.

Seit 2010 leitete Martin Beck die Forschungsgruppe Structure and function of large macromolecular assemblies am EMBL, wo er seine Methodik weiter verfeinert und ausgeweitet hat. Mit der Förderung durch ERC Grants (2013 und 2018) konnte das Team die Zusammensetzung und Struktur der menschlichen Kernpore im Detail erfassen und zelltyp-spezifische Unterschiede charakterisieren. Sein Team untersuchte die Biogenese der Bestandteile von Kernporen in Eizellen von Drosophila melanogaster und konnte zeigen, dass diese vererbt werden, wodurch die frühe Embryonalentwicklung von der Mutter unterstützt wird.
Die traditionelle Vorstellung von Zellen, in denen sich unterschiedliche Moleküle zufällig treffen, um chemische Reaktionen miteinander einzugehen, ist mittlerweile überholt. Der Begriff „Molekulare Soziologie“ bezieht sich auf das Studium der Bindungen, welche die molekularen Bestandteile von Zellen kurz- oder längerfristig miteinander eingehen. Mit der neuen Abteilung in Frankfurt plant Martin Beck, biophysikalische Methoden anzuwenden, um solche molekularen Beziehungen zu studieren.

Webseite Martin Beck, EMBL:
Structure and function of large macromolecular assemblies


Rumford-Preis der American Academy of Arts and Sciences

Prof. Dr. Ernst Bamberg


11. April 2019
Ernst Bamberg, langjähriger Direktor der Abteilung „Biophysikalische Chemie“, hat zusammen mit Ed Boyden, (Boston, USA), Karl Deisseroth (Stanford, USA), Peter Hegemann (Berlin), Gero Miesenböck (Oxford, GB) und Georg Nagel (Würzburg) den renommierten Rumford-Preis der American Academy of Arts and Sciences erhalten. Es ist der älteste Preis (seit 1839), den die Akademie zu vergeben hat. Die Wissenschaftler werden in „Anerkennung für ihre außerordentlichen Beiträge zur Entdeckung und Entwicklung der Optogenetik“ geehrt.

Die Preisverleihung fand am 11. April 2019 am Hauptsitz der Akademie in Cambridge (MA, USA) statt.

Die Verlautbarung der American Academy zur Verleihung des Preises:

“A storied science prize that was awarded to Thomas Edison in 1895 for his work in electric lighting; Edwin Land in 1945 for his applications in polarized light and photography; Enrico Fermi in 1953 for his studies of radiation theory and nuclear energy; and Federico Capasso and Alfred Cho in 2015 for their contributions to the field of laser technology will next be awarded to Ernst Bamberg, Ed Boyden, Karl Deisseroth, Peter Hegemann, Gero Miesenböck, and Georg Nagel in recognition of their extraordinary contributions related to the invention and refinement of optogenetics.

First awarded in 1839, the Rumford Prize given by the American Academy of Arts and Sciences recognizes contributions to the fields of heat and light. The Rumford Prize will next be presented during the Academy’s Annual Awards Ceremony on April 11, 2019, at the Academy’s headquarters in Cambridge, Massachusetts. Named “Breakthrough of the Decade” in 2010 by the journal Science, the field of optogenetics has furthered the fundamental scientific understanding of how specific cell types contribute to the function of biological tissues. On the clinical side, optogenetics-driven research has led to insights into Parkinson’s disease and other neurological and psychiatric disorders, as well as autism, schizophrenia, drug abuse, anxiety, and depression.

As Lucia Rothman-Denes, a member of the Academy’s Prize Committee and the A.J. Carlson Professor of Molecular Genetics and Cell Biology at the University of Chicago, stated, “Optogenetics has revolutionized the field of neuroscience,” and added “the work undertaken by these scientists has had a profound impact on cell biology and, most recently, microbiology in ways that advance our understanding of science and of health.”
“On behalf of the American Academy, I am pleased to present the Rumford Prize to Professors Bamberg, Boyden, Deisseroth, Hegemann, Miesenböck, and Nagel for their achievements,” said David W. Oxtoby, President of the American Academy of Arts and Sciences. “Along with Alexander Graham Bell, Albert Einstein, Niels Bohr, and others, they are part of a distinguished lineage of scientists who have been honored by the Academy.”


Weitere Informationen unter:
https://www.amacad.org/news/rumford-prize-optogenetics



Ivan Dikic appointed as MAX PLANCK FELLOW

Prof. Dr. Ivan Đikić

October 2018, we are happy to share our knowledge and infrastructure with Prof. Ivan Đikić.

Ivan Đikić is appointed as MAX PLANCK FELLOW at the Max Planck Institute of Biophysics

The molecular biologist and biochemist Ivan Đikić, Director of the Institute of Biochemistry II at Goethe University Frankfurt am Main, has been appointed as Fellow of the Max Planck Society. He started his term at the Max Planck Institute of Biophysics in October 2018.
The Max Planck Fellow Programme promotes cooperation between outstanding university professors and Max Planck Society researchers.
The appointment as Max Planck Fellow entails the supervision of a small working group at a Max Planck Institute for a five years term.
Research in the Đikić group is centered around two major cellular quality control pathways: the ubiquitin system and autophagy. As such they provide protection against various human diseases and are involved in almost all cellular signaling processes. The group covers a wide range of expertise to reveal structure-function relationships. Recently, the Đikić Molecular Signaling Group revealed a novel ubiquitination mechanism induced by bacterial enzymes upon infection of human cells. In collaboration with colleagues at the Frankfurt Max Planck Institute of Biophysics, the group now aims to resolve additional atomic details of this serine ubiquitination. A second area of mutual interest is in remodeling of endoplasmic reticulum via a process known as ER-phagy. Until now, very little is known about the mechanisms facilitating membrane targeting, bending and shaping during this selective form of autophagy.
In addition, Ivan Đikić aims to also build strong links to the highly competitive cancer research programme at Goethe University. He is one of the founders of the Frankfurt Cancer Institute (FCI), which has recently received significant funding for building up a LOEWE center and a new research building.
Professor Đikić was honoured with numerous prizes including the Gottfried Wilhelm Leibniz Prize 2013 (DFG), two European Research Council (ERC) Advanced Grants, the Ernst Jung Prize for Medicine and the German Cancer Prize (Deutscher Krebspreis) by the German Cancer Society.
Ivan Đikić is deeply committed towards education of the next generation of scientists and to communication of science to the public. He sustains strong links to his homeland Croatia, where his efforts in both education and communication have been recognized by the highest civilian honour, The Order of Duke Branimir, bestowed by the President of Croatia.

Link to his research:
Molecular Signaling Group

Kontaktinformationen:

Max-Planck-Institut für Biophysik

Presse- und Öffentlichkeitsarbeit

Dipl.-Chem. Brigitte Holfelder

Max-von-Laue-Straße 3
60438 Frankfurt am Main
Tel.: +49 (0) 69 6303-3020
email: pressestelle@biophys.mpg.de

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