Publikationen von Hartmut Michel

Zeitschriftenartikel (251)

1.
Zeitschriftenartikel
Schleker, E. S. M.; Buschmann, S.; Xie, H.; Welsch, S.; Michel, H.; Reinhart, C.: Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proceedings of the National Academy of Sciences of the United States of America 119 (43), e2202822119 (2022)
2.
Zeitschriftenartikel
Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Münke, C.; Robinson, C. V.; Hummer, G.; Xie, H. et al.; Michel, H.: Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism. The EMBO Journal 41 (18), e109990 (2022)
3.
Zeitschriftenartikel
Meier-Credo, J.; Preiss, L.; Wüllenweber, I.; Resemann, A.; Nordmann, C.; Zabret, J.; Suckau, D.; Michel, H.; Nowacyk, M. M.; Meier, T. et al.; Langer, J. D.: Top-Down Identification and Sequence Analysis of Small Membrane Proteins Using MALDI-MS/MS. Journal of the American Society for Mass Spectrometry 33 (7), S. 1293 - 1302 (2022)
4.
Zeitschriftenartikel
Zhao, J.; Hellwig, N.; Djahanschiri, B.; Khera, R.; Morgner, N.; Ebersberger, I.; Wang, J.; Michel, H.: Assembly and Functional Role of PACE Transporter PA2880 from Pseudomonas aeruginosa. Microbiology Spectrum 10 (2), e01453-21 (2022)
5.
Zeitschriftenartikel
Grund, T. N.; Radloff, M.; Wu, D.; Goojani, H. G.; Witte, L. F.; Jösting, W.; Buschmann, S.; Müller, H.; Elamri, I.; Welsch, S. et al.; Schwalbe, H.; Michel, H.; Bald, D.; Safarian, S.: Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 118 (50), e2114013118 (2021)
6.
Zeitschriftenartikel
Kolbe, F.; Safarian, S.; Piórek, Ż.; Welsch, S.; Müller, H.; Michel, H.: Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications 12, 6903 (2021)
7.
Zeitschriftenartikel
Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)
8.
Zeitschriftenartikel
Safarian, S.; Opel-Reading, H. K.; Wu, D.; Mehdipour, A. R.; Hards, K.; Harold, L. H.; Radloff, M.; Stewart, I.; Welsch, S.; Hummer, G. et al.; Cook, G. M.; Krause, K. L.; Michel, H.: The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications 12 (1), 5236 (2021)
9.
Zeitschriftenartikel
Nikolaev, A.; Safarian, S.; Thesseling, A.; Wohlwend, D.; Friedrich, T.; Michel, H.; Kusumoto, T.; Sakamoto, J.; Melin, F.; Hellwig, P.: Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics 1862 (8), e148436 (2021)
10.
Zeitschriftenartikel
Zhu, G.; Zeng, H.; Zhang, S.; Juli, J.; Tai, L.; Zhang, D.; Pang , X.; Zhang, Y.; Lam, S. M.; Zhu, Y. et al.; Peng, G.; Michel, H.; Sun, F.: The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English 60 (24), S. 13323 - 13330 (2021)
11.
Zeitschriftenartikel
Wu, D.; Grund, T. N.; Welsch, S.; Mills, D.; Michel, M.; Safarian, S.; Michel, H.: Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America 117 (35), 202008111, S. 21281 - 21287 (2020)
12.
Zeitschriftenartikel
Elamri, I.; Radloff, M.; Hohmann, K. F.; Nimbarte, V. D.; Nasiri, H. R.; Bolte, M.; Safarian, S.; Michel, H.; Schwalbe, H.: Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo3 Ubiquinol Oxidase from Escherichia coli. ChemMedChem 15 (14), S. 1262 - 1271 (2020)
13.
Zeitschriftenartikel
Zeng, H.; Zhu, G.; Zhang, S.; Li, X.; Martin, J.; Morgner, N.; Sun, F.; Peng, G.; Xie, H.; Michel, H.: Isolated Heme A Synthase from Aquifex aeolicus Is a Trimer. mBio 11 (3), e02615-19 (2020)
14.
Zeitschriftenartikel
Zhu, G.; Zeng, H.; Zang, S.; Juli, J.; Pang, X.; Hoffman, J.; Zhang, Y.; Morgner, N.; Zhu, Y.; Peng, G. et al.; Michel, H.; Sun, F.: A 3.3 Å‐Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of its Thermal Stability. Angewandte Chemie, International Edition in English 59 (1), S. 343 - 351 (2020)
15.
Zeitschriftenartikel
Lencina, A. M.; Koepke, J.; Preu, J.; Münke, C.; Gennis, R. B.; Michel, H.; Schurig-Briccio, L. A.: Characterization and X-ray structure of the NADH-dependent coenzyme A disulfide reductase from Thermus thermophilus. Biochimica et Biophysica Acta, Bioenergetics 1860 (11), e148080 (2019)
16.
Zeitschriftenartikel
Safarian, S.; Hahn, A.; Mills, D.; Radloff, M.; Eisinger, M. L.; Nikolaev, A.; Meier-Credo, J.; Melin, F.; Miyoshi, H.; Gennis, R.B. et al.; Sakamoto, J.; Langer, J. D.; Hellwig, P.; Kühlbrandt, W.; Michel, H.: Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366 (6461), S. 100 - 104 (2019)
17.
Zeitschriftenartikel
Zakrzewska, S.; Mehdipour, A. R.; Malviya, V. N.; Nonaka, T.; Koepke, J.; Muenke, C.; Hausner, W.; Hummer, G.; Safarian, S.; Michel, H.: Inward-facing conformation of a multidrug resistance MATE family transporter. Proceedings of the National Academy of Sciences of the United States of America 116 (25), S. 12275 - 12284 (2019)
18.
Zeitschriftenartikel
Richter, M.; Moroniak, S. J.; Michel, H.: Identification of competitive inhibitors of the human taurine transporter TauT in a human kidney cell line. Pharmacological Reports 71 (1), S. 121 - 127 (2019)
19.
Zeitschriftenartikel
Liu, W.; Liu, A.; Gao, H.; Wang, Q.; Wang, L.; Warkentin, E.; Rao, Z.; Michel, H.; Peng, G.: Structural properties of the peroxiredoxin AhpC2 from the hyperthermophilic eubacterium Aquifex aeolicus. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (12), S. 2797 - 2805 (2018)
20.
Zeitschriftenartikel
Peng, G.; Meyer, B.; Sokolova, L.; Liu, W.; Bornemann, S.; Juli, J.; Zwicker, K.; Karas, M.; Brutschy, B.; Michel, H.: Identification and characterization two isoforms of NADH:ubiquinone oxidoreductase from the hyperthermophilic eubacterium Aquifex aeolicus. Biochimica et Biophysica Acta, Bioenergetics 1859 (5), S. 366 - 373 (2018)
21.
Zeitschriftenartikel
Eisinger, M. L.; Nie, L.; Dörrbaum, A. R.; Langer, J. D.; Michel, H.: The Xenobiotic Extrusion Mechanism of the MATE Transporter NorM_PS from Pseudomonas stutzeri. Journal of Molecular Biology (London) 430 (9), S. 1311 - 1323 (2018)
22.
Zeitschriftenartikel
Joedicke, L.; Mao, J.; Kuenze, G.; Reinhart, C.; Kalavacherla, T.; Jonker, H. R.A.; Richter, C.; Schwalbe, H.; Meiler, J.; Preu, J. et al.; Michel, H.; Glaubitz, C.: The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nature Chemical Biology 13 (3), S. 284 - 290 (2018)
23.
Zeitschriftenartikel
Eisinger, M. L.; Dörrbaum, A. R.; Michel, H.; Padan, E.; Langer, J. D.: Ligand-induced conformational dynamics of the Escherichia coli Na+/H+ antiporter NhaA revealed by hydrogen/deuterium exchange mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 114 (44), S. 11691 - 11696 (2017)
24.
Zeitschriftenartikel
Sommer, M.; Xie, H.; Michel, H.: Pseudomonas stutzeri as an alternative host for membrane proteins. Microbial Cell Factories 16, 157 (2017)
25.
Zeitschriftenartikel
Kohlstädt, M.; Buschmann, S.; Langer, J. D.; Xie, H.; Michel, H.: Subunit CcoQ is involved in the assembly of the Cbb3-type cytochrome c oxidases from Pseudomonas stutzeri ZoBell but not required for their activity. Biochimica et Biophysica Acta, Bioenergetics 1858 (3), S. 231 - 238 (2017)
26.
Zeitschriftenartikel
Laiyin, N.; Grell, E.; Malviya, V. N.; Xie, H.; Wang, J.; Michel, H.: Identification of the High-affinity Substrate-binding Site of the Multidrug and Toxic Compound Extrusion (MATE) Family Transporter from Pseudomonas stutzeri. The Journal of Biological Chemistry 291 (30), S. 15503 - 15514 (2016)
27.
Zeitschriftenartikel
Safarian, S.; Rajendran, C.; Müller, H.; Preu, J.; Langer, J. D.; Ovchinnikov, S.; Hirose, T.; Kusumoto, T.; Sakamoto, J.; Michel, H.: Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases. Science 352 (6285), S. 583 - 586 (2016)
28.
Zeitschriftenartikel
Srinivasan, L.; Baars, T. L.; Fendler, K.; Michel, H.: Functional characterization of solute carrier (SLC) 26/sulfate permease (SulP) proteins in membrane mimetic systems. Biochimica et Biophysica Acta-Biomembranes 1858 (4), S. 698 - 705 (2016)
29.
Zeitschriftenartikel
Kohlstädt, M.; Buschmann, S.; Xie, H.; Resemann, A.; Warkentin, E.; Langer, J. D.; Michel, H.: Identification and characterization of the novel subunit CcoM in the cbb3-cytochrome c oxidase from Pseudomonas stutzeri ZoBell. mBio 7 (7), S. 1 - 9 (2016)
30.
Zeitschriftenartikel
Joedicke, L.; Trenker, R.; Langer, J. D.; Michel, H.; Preu, J.: Cell-free synthesis of isotopically labelled peptide ligands for the functional characterization of G protein-coupled receptors. FEBS Open Bio 6 (1), S. 90 - 102 (2016)
31.
Zeitschriftenartikel
Padan, E.; Michel, H.: NhaA: A Unique Structural Fold of Secondary Active Transporters. Israel Journal of Chemistry 55 (11/12), S. 1233 - 1239 (2015)
32.
Zeitschriftenartikel
Kohlstädt, M.; von der Hocht, I.; Hilbers, F.; Thielmann, Y.; Michel, H.: Development of a Thermofluor assay for stability determination of membrane proteins using the Na+/H+antiporter NhaA and cytochrome c oxidase. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 71 (5), S. 1112 - 1122 (2015)
33.
Zeitschriftenartikel
Meyer, T.; Melin, F.; Richter, O.-M.H.; Ludwig, B.; Kannt, A.; Müller, H.; Michel, H.; Hellwig, P.: Electrochemistry suggests proton access from the exit site to the binuclear center in Paracoccus denitrificans cytochrome c oxidase pathway variants. FEBS Letters 589 (5), S. 565 - 568 (2015)
34.
Zeitschriftenartikel
Meyer, T.; Melin, F.; Xie, H.; von der Hocht, I.; Choi, S. K.; Noor, M. R.; Michel, H.; Gennis, R. B.; Soulimane, T.; Hellwig, P.: Evidence for Distinct Electron Transfer Processes in Terminal Oxidases from Different Origin by Means of Protein Film Voltammetry. Journal of the American Chemical Society 136 (31), S. 10821 - 11196 (2014)
35.
Zeitschriftenartikel
Buschmann, S.; Richers, S.; Ermler, U.; Michel, H.: A decade of crystallization drops: Crystallization of the cbb3 cytochrome c oxidase from Pseudomonas stutzeri. Protein Science 23 (4), S. 411 - 422 (2014)
36.
Zeitschriftenartikel
Kaur, J.; Olkhova, E.; Malviya, V. N.; Grell, E.; Michel, H.: A L-Lysine Transporter of High Stereoselectivity of the Amino Acid-Polyamine-Organocation (APC) Superfamily PRODUCTION, FUNCTIONAL CHARACTERIZATION, AND STRUCTURE MODELING. The Journal of Biological Chemistry 289 (3), S. 1377 - 1387 (2014)
37.
Zeitschriftenartikel
Xie, H.; Buschmann, S.; Langer, J. D.; Ludwig, B.; Michel, H.: Biochemical and Biophysical Characterization of the Two Isoforms of cbb3-Type Cytochrome c Oxidase from Pseudomonas stutzeri. Journal of Bacteriology (Washington, DC) 196 (2), S. 472 - 482 (2014)
38.
Zeitschriftenartikel
Zhang, C.; Allegretti, M.; Vonck, J.; Langer, J.; Marcia, M.; Peng, G.; Michel, H.: Production of fully assembled and active Aquifex aeolicus F1FO ATP synthase in Escherichia coli. Biochimica et Biophysica Acta (BBA) - General Subjects 1840 (1), S. 34 - 40 (2014)
39.
Zeitschriftenartikel
Kozuch, J.; von der Hocht, I.; Hilbers, F.; Michel, H.; Weidinger, I. M.: Resonance Raman Characterization of the Ammonia-Generated Oxo Intermediate of Cytochrome c Oxidase from Paracoccus denitrificans. Biochemistry 52 (36), S. 6197 - 6202 (2013)
40.
Zeitschriftenartikel
Ruehrer, S.; Michel, H.: Exploiting Leishmania tarentolae cell-free extracts for the synthesis of human solute carriers. Molecular Membrane Biology 30 (4), S. 288 - 302 (2013)
41.
Zeitschriftenartikel
Zhang, C.; Marcia, M.; Langer, J. D.; Peng, G.; Michel, H.: Role of the N-terminal signal peptide in the membrane insertion of Aquifex aeolicus F1F0 ATP synthase c-subunit. The FEBS Journal 280 (14), S. 3425 - 3435 (2013)
42.
Zeitschriftenartikel
Hilbers, F.; von der Hocht, I.; Ludwig, B.; Michel, H.: True wild type and recombinant wild type cytochrome c oxidase from Paracoccus denitrificans show a 20-fold difference in their catalase activity. Biochimica et Biophysica Acta, Bioenergetics 1827 (3), S. 319 - 327 (2013)
43.
Zeitschriftenartikel
Kirchberg, K.; Michel, H.; Alexiev, U.: Exploring the entrance of proton pathways in cytochrome c oxidase from Paracoccus denitrificans: Surface charge, buffer capacity and redox-dependent polarity changes at the internal surface. Biochimica et Biophysica Acta, Bioenergetics 1827 (3), S. 276 - 284 (2013)
44.
Zeitschriftenartikel
Jaehme, M.; Michel, H.: Evaluation of cell-free protein synthesis for the crystallization of membrane proteins – a case study of the glutamate transporter family from Staphylothermus marinus. The FEBS Journal 280 (4), S. 1112 - 1125 (2013)
45.
Zeitschriftenartikel
Wang, T.; Langer, J. D.; Peng, G.; Michel, H.: Isolation, functional characterization and crystallization of Aq_1259, an outer membrane protein with porin features, from Aquifex aeolicus. Biochimica et Biophysica Acta-Proteins and Proteomics 1824 (12), S. 1358 - 1365 (2012)
46.
Zeitschriftenartikel
Goswami, D.; Kaur, J.; Surade, S.; Grell, E.; Michel, H.: Heterologous production and functional and thermodynamic characterization of cation diffusion facilitator (CDF) transporters of mesophilic and hyperthermophilic origin. Biological Chemistry 393 (7), S. 617 - 629 (2012)
47.
Zeitschriftenartikel
Thielmann, Y.; Koepke, J.; Michel, H.: The ESFRI Instruct Core Centre Frankfurt: automated high-throughput crystallization suited for membrane proteins and more. Journal of Structural and Functional Genomics, S. 63 - 69 (2012)
48.
Zeitschriftenartikel
Rycovska, A.; Hatahet, L.; Fendler, K.; Michel, H.: The nitrite transport protein NirC from Salmonella typhimurium is a nitrite/proton antiporter. Biochimica et Biophysica Acta-Biomembranes 1818 (5), S. 1342 - 1350 (2012)
49.
Zeitschriftenartikel
Michel, H.: The Nonsense of Biofuels. Angewandte Chemie, International Edition in English 51 (11), S. 2516 - 2518 (2012)
50.
Zeitschriftenartikel
Kirchberg, K.; Michel, H.; Alexiev, U.: Net Proton Uptake Is Preceded by Multiple Proton Transfer Steps upon Electron Injection into Cytochrome c Oxidase. The Journal of Biological Chemistry 287 (11), S. 8187 - 8193 (2012)
51.
Zeitschriftenartikel
Gao, Y.; Meyer, B.; Sokolova, L.; Zwicker, K.; Karas, M.; Brutschy, B.; Peng, G.; Michel, H.: Heme-copper terminal oxidase using both cytochrome c and ubiquinol as electron donors. Proceedings of the National Academy of Sciences of the United States of America 109 (9), S. 3275 - 3280 (2012)
52.
Zeitschriftenartikel
von der Hocht, I.; van Wonderen, J. H.; Hilbers, F.; Angerer, H.; MacMillan, F.; Michel, H.: Interconversions of P and F intermediates of cytochrome c oxidase from Paracoccus denitrificans. Proceedings of the National Academy of Sciences of the United States of America 108 (10), S. 3964 - 3969 (2011)
53.
Zeitschriftenartikel
Hedderich, T.; Marcia, M.; Köpke, J.; Michel, H.: PICKScreens, A New Database for the Comparison of Crystallization Screens for Biological Macromolecules. Crystal Growth & Design 11 (2), S. 488 - 491 (2011)
54.
Zeitschriftenartikel
MacMillan, F.; Kacprzak, S.; Hellwig, P.; Grimaldi, S.; Michel, H.; Kaupp, M.: The high-affinity QH binding site in quinol oxidase as studied by DONUT-HYSCORE spectroscopy and density functional theory. Faraday Discussions 148, S. 315 - 344 (2011)
55.
Zeitschriftenartikel
Marcia, M.; Langer, J. D.; Parcej, D.; Vogel, V.; Peng, G.; Michel, H.: Characterizing a monotopic membrane enzyme. Biochemical, enzymatic and crystallization studies on Aquifex aeolicus sulfide:quinone oxidoreductase. Biochimica et Biophysica Acta-Biomembranes 1798 (11), S. 2114 - 2123 (2010)
56.
Zeitschriftenartikel
Buschmann, S.; Warkentin, E.; Xie, H.; Langer, J. D.; Ermler, U.; Michel, H.: The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping. Science 329 (5989), S. 327 - 330 (2010)
57.
Zeitschriftenartikel
Rajendran, C.; Ermler, U.; Ludwig, B.; Michel, H.: Structure at 1.5 Å resolution of cytochrome c552 with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D66 (7), S. 850 - 854 (2010)
58.
Zeitschriftenartikel
Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: A new structure-based classification of sulfide:quinone oxidoreductases. Proteins: Structure, Function, and Bioinformatics 78 (5), S. 1073 - 1083 (2010)
59.
Zeitschriftenartikel
Clason, T.; Ruiz, T.; Schägger, H.; Peng, G.; Zickermann, V.; Brandt, U.; Michel, H.; Radermacher, M.: The structure of eukaryotic and prokaryotic complex I. Journal of Structural Biology 169 (1), S. 81 - 88 (2010)
60.
Zeitschriftenartikel
Baier, J.; Gabrielsen, M.; Oellerich, S.; Michel, H.; van Heel, M.; Cogdell, R. J.; Köhler, J.: Spectral Diffusion and Electron-Phonon Coupling of the B800 BChl a Molecules in LH2 Complexes from Three Different Species of Purple Bacteria. Biophysical Journal 97 (9), S. 2604 - 2612 (2009)
61.
Zeitschriftenartikel
Olkhova, E.; Kozachkov, L.; Padan, E.; Michel, H.: Combined computational and biochemical study reveals the importance of electrostatic interactions between the ‘‘pH sensor’’ and the cation binding site of the sodium/proton antiporter NhaA of Escherichia coli. Proteins: Structure, Function, and Bioinformatics 76 (3), S. 548 - 559 (2009)
62.
Zeitschriftenartikel
Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proceedings of the National Academy of Sciences of the United States of America 106 (24), S. 9625 - 9630 (2009)
63.
Zeitschriftenartikel
Koepke, J.; Olkhova, E.; Angerer, H.; Müller, H.; Peng, G.; Michel, H.: High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways. Biochimica et Biophysica Acta, Bioenergetics 1787 (6), S. 635 - 645 (2009)
64.
Zeitschriftenartikel
Xia, H.; Liu, L.; Reinhart, C.; Michel, H.: Heterologous expression of human Neuromedin U receptor 1 and its subsequent solubilization and purification. Biochimica et Biophysica Acta-Biomembranes 1778 (10), S. 2203 - 2209 (2008)
65.
Zeitschriftenartikel
Rimon, A.; Hunte, C.; Michel, H.; Padan, E.: Epitope Mapping of Conformational Monoclonal Antibodies Specific to NhaA Na+/H+ antiporter: Structural and Functional Implications. Journal of Molecular Biology (London) 379 (3), S. 471 - 481 (2008)
66.
Zeitschriftenartikel
Lopez, J. J.; Shukla, A. K.; Reinhart, C.; Schwalbe, H.; Michel, H.; Glaubitz, C.: The Structure of the Neuropeptide Bradykinin Bound to the Human G-Protein Coupled Receptor Bradykinin B2 as Determined by Solid-State NMR Spectroscopy. Angewandte Chemie 120 (9), S. 1692 - 1695 (2008)
67.
Zeitschriftenartikel
Dürr, K. L.; Koepke, J.; Hellwig, P.; Müller, H.; Angerer, H.; Peng, G.; Olkhova, E.; Richter, O.-M. H.; Ludwig, B.; Michel, H.: A D-Pathway Mutation Decouples the Paracoccus denitrificans Cytochrome c Oxidase by Altering the Side-Chain Orientation of a Distant Conserved Glutamate. Journal of Molecular Biology (London) 384 (4), S. 865 - 877 (2008)
68.
Zeitschriftenartikel
Roy, A.; Shukla, A. K.; Haase, W.; Michel, H.: Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors. Biological Chemistry Hoppe-Seyler 389 (1), S. 69 - 78 (2008)
69.
Zeitschriftenartikel
Chillakuri, C. R.; Reinhart, C.; Michel, H.: C-terminal truncated cannabinoid receptor 1 co-expressed with G protein trimer in Sf9 cells exist in a precoupled state and show constitutive activity. The FEBS Journal 274 (23), S. 6106 - 6115 (2007)
70.
Zeitschriftenartikel
Srinivasan, V.; Netz, D. J. A.; Webert, H.; Mascarenhas, J.; Plerik, A. J.; Michel, H.; Lill, R.: Structure of the Yeast WD40 Domain Protein Cia1, a Component Acting Late in Iron-Sulfur Protein Biogenesis. Structure 15 (10), S. 1246 - 1257 (2007)
71.
Zeitschriftenartikel
Wedemeyer, U.; Peng, G.; Michel, H.; Hartung, K.: Protein AQ_1862 from the Hyperthermophilic Bacterium Aquifex aeolicus is a Porin and Contains Two Conductance Pathways of Different Selectivity. Biophysical Journal 93 (8), S. 2667 - 2677 (2007)
72.
Zeitschriftenartikel
Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Heterologous expression and characterization of the recombinant bradykinin B2 receptor using the methylotrophic yeast Pichia pastoris. Protein Expression and Purification 55 (1), S. 1 - 8 (2007)
73.
Zeitschriftenartikel
Klammt, C.; Srivastava, A.; Eifler, N.; Junge, F.; Beyermann, M.; Schwarz, D.; Michel, H.; Doetsch, V.; Bernhard, F.: Functional analysis of cell-free produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation. The FEBS Journal 274 (13), S. 3257 - 3269 (2007)
74.
Zeitschriftenartikel
Olkhova, E.; Padan, E.; Michel, H.: The Influence of Protonation States on the Dynamics of the NhaA Antiporter from Escherichia coli. Biophysical Journal 92 (11), S. 3784 - 3791 (2007)
75.
Zeitschriftenartikel
Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. The International Journal of Biochemistry & Cell Biology 39 (5), S. 931 - 942 (2007)
76.
Zeitschriftenartikel
Peng, G.; Bostina, M.; Radermacher, M.; Rais, I.; Karas, M.; Michel, H.: Biochemical and electron microscopic characterization of the F1F0 ATP Synthase from the hyperthermophilic eubacterium Aquifex aeolicus. FEBS Letters 580 (25), S. 5934 - 5940 (2006)
77.
Zeitschriftenartikel
Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Functional Overexpression and Characterization of Human Bradykinin Subtype 2 Receptor in Insect Cells Using the Baculovirus System. Journal of Cellular Biochemistry 99 (3), S. 868 - 877 (2006)
78.
Zeitschriftenartikel
Shukla, A. K.; Reinhart, C.; Michel, H.: Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells. Biochemical and Biophysical Research Communications 349 (1), S. 6 - 14 (2006)
79.
Zeitschriftenartikel
Screpanti, E.; Padan, E.; Rimon, A.; Michel, H.; Hunte, C.: Crucial Steps in the Structure Determination of the Na+/H+ Antiporter NhaA in its Native Conformation. Journal of Molecular Biology (London) 362 (2), S. 192 - 202 (2006)
80.
Zeitschriftenartikel
Surade, S.; Klein, M.; Stolt-Bergner, P. C.; Muenke, C.; Roy, A.; Michel, H.: Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Science 15 (9), S. 2178 - 2189 (2006)
81.
Zeitschriftenartikel
Shukla, A. K.; Reinhart, C.; Michel, H.: Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells. FEBS Letters 580 (17), S. 4261 - 4265 (2006)
82.
Zeitschriftenartikel
Lundstrom, K.; Wagner, R.; Reinhart, C.; Desmyter, A.; Cherouati, N.; Magnin, T.; Zeder-Lutz, G.; Courtot, M.; Prual, C.; André, N. et al.; Hassaine, G.; Michel, H.; Cambillau, C.; Pattus, F.: Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. Journal of Structural and Functional Genomics 7 (2), S. 77 - 91 (2006)
83.
Zeitschriftenartikel
André, N.; Cherouati, N.; Prual, C.; Steffan, T.; Zeder-Lutz, G.; Magnin, T.; Pattus, F.; Michel, H.; Wagner, R.; Reinhart, C.: Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Science 15 (5), S. 1115 - 1126 (2006)
84.
Zeitschriftenartikel
Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system. Biological Chemistry 387 (5), S. 569 - 576 (2006)
85.
Zeitschriftenartikel
Farver, O.; Grell, E.; Ludwig, B.; Michel, H.; Pecht, I.: Rates and Equilibrium of CuA to Heme a Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase. Biophysical Journal 90, S. 2131 - 2137 (2006)
86.
Zeitschriftenartikel
Olkhova, E.; Hunte, C.; Screpanti, E.; Padan, E.; Michel, H.: Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications. Proceedings of the National Academy of Sciences of the United States of America 103 (8), S. 2629 - 2634 (2006)
87.
Zeitschriftenartikel
MacMillan, F.; Budiman, K.; Angerer, H.; Michel, H.: The role of tryptophan 272 in the Paracoccus denitrificans cytochrome c oxidase. FEBS Letters 580 (5), S. 1345 - 1349 (2006)
88.
Zeitschriftenartikel
Olkhova, E.; Helms, V.; Michel, H.: Titration Behavior of Residues at the Entrance of the D-Pathway of Cytochrome c Oxidase from Paracoccus denitrificans Investigated by Continuum Electrostatic Calculations. Biophysical Journal 89 (4), S. 2324 - 2331 (2005)
89.
Zeitschriftenartikel
Hunte, C.; Screpanti, E.; Venturi, M.; Rimon, A.; Padan, E.; Michel, H.: Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH. Nature 435 (7046), S. 1197 - 1202 (2005)
90.
Zeitschriftenartikel
Hofmann, C.; Michel, H.; van Heel, M.; Köhler, J.: Multivariate Analysis of Single-Molecule Spectra: Surpassing Spectral Diffusion. Physical Review Letters 94 (19), 195501 (2005)
91.
Zeitschriftenartikel
Barleben, L.; Ma, X.; Koepke, J.; Peng, G.; Michel, H.; Stöckigt, J.: Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Proteins & Proteomics, S. 89 - 92 (2005)
92.
Zeitschriftenartikel
Srinivasan, V.; Rajendran, C.; Sousa, F. L.; Melo, A. M.P.; Saraiva, L. M.; Pereira, M. M.; Santana, M.; Teixeira, M.; Michel, H.: Structure at 1.3 Å Resolution of Rhodothermus marinus caa3 Cytochrome c Domain. Journal of Molecular Biology (London) 345 (5), S. 1047 - 1057 (2005)
93.
Zeitschriftenartikel
Ma, X.; Koepke, J.; Fritzsch, G.; Diem, R.; Kutchan, T. M.; Michel, H.; Stöckigt, J.: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochimica et Biophysica Acta-Proteins and Proteomics 1702, S. 121 - 124 (2004)
94.
Zeitschriftenartikel
Budiman, K.; Kannt, A.; Lyubenova, S.; Richter, O.-M.; Ludwig, B.; Michel, H.; MacMillan, F.: Tyrosine-167: The Origin of the Radical Species Observed in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide in Paracoccus denitrificans. Biochemistry 43 (37), S. 11709 - 11716 (2004)
95.
Zeitschriftenartikel
Ma, X.; Koepke, J.; Bayer, A.; Linhard, V.; Fritzsch, G.; Zhang, B.; Michel, H.; Stöckigt, J.: Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochimica et Biophysica Acta-Proteins and Proteomics 1701 (1-2), S. 129 - 132 (2004)
96.
Zeitschriftenartikel
Cismasiu, V. B.; Denes, S. A.; Reiländer, H.; Michel, H.; Szedlacsek, S. E.: The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase µ. The Journal of Biological Chemistry 279 (26), S. 26922 - 26931 (2004)
97.
Zeitschriftenartikel
Maeda, Y.; Kuroki, R.; Haase, W.; Michel, H.; Reiländer, H.: Comparative analysis of high-affinity ligand binding and G protein coupling of the human CXCR1 chemokine receptor and of a CXCR1-Gi2α fusion protein after heterologous production in baculovirus-infected insect cells. European Journal of Biochemistry 271, S. 1677 - 1689 (2004)
98.
Zeitschriftenartikel
Olkhova, E.; Hutter, M. C.; Lill, M. A.; Helms, V.; Michel, H.: Dynamic Water Networks in Cytochrome c Oxidase from Paracoccus denitrificans Investigated by Molecular Dynamics Simulations. Biophysical Journal 86 (4), S. 1873 - 1889 (2004)
99.
Zeitschriftenartikel
Hofman, C.; Aartsma, T. J.; Michel, H.; Köhler, J.: Spectral dynamics in the B800 band of LH2 from Rhodospirillum molischianum: a single-molecule study. New Journal of Physics 6, S. 1 - 15 (2004)
100.
Zeitschriftenartikel
Grünewald, S.; Haase, W.; Molsberger, E.; Michel, H.; Reiländer, H.: Production of the Human D2S Receptor in the Methylotrophic Yeast P. pastoris. Receptors and Channels 10 (1), S. 37 - 50 (2004)
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