Max-Planck-Institut für Biophysik

Publikationen von Hartmut Michel

Alle Typen

Zeitschriftenartikel (257)

1.

Zeitschriftenartikel

Meier-Credo, J.; Heiniger, B.; Schori, C.; Rupprecht, F.; Michel, H.; Ahrens, C. A.; Langer, J. D.: Detection of Known and Novel Small Proteins in Pseudomonas stutzeri Using a Combination of Bottom-Up and Digest-Free Proteomics and Proteogenomics. Analytical Chemistry (2023)

MPG.PuRe

2.

Zeitschriftenartikel

Kalavacherla, T.; Buschmann, S.; Schleker, E. S. M.; Michel, H.; Reinhart, C.: Purification and characterization of eukaryotic ATP-dependent transporters homologously expressed in Pichia pastoris for structural studies by cryo-electron microscopy. Protein Expression and Purification 204, 106230 (2023)

MPG.PuRe

3.

Zeitschriftenartikel

Hegemann, P.; Michel, H.: Dieter Oesterhelt (1940–2022). Science 379 (6630), S. 337 (2023)

MPG.PuRe

4.

Zeitschriftenartikel

Xie, H.; Lyratzakis, A.; Khera, R.; Koutantou, M.; Welsch, S.; Michel, H.; Tsiotis, G.: Cryo-EM structure of the whole photosynthetic reaction center apparatus from the green sulfur bacterium Chlorobaculum tepidum. Proceedings of the National Academy of Sciences of the United States of America 120 (5), e2216734120 (2023)

MPG.PuRe

5.

Zeitschriftenartikel

Grund, T. N.; Kabashima, Y.; Kusumoto, T.; Wu, D.; Welsch, S.; Sakamoto, J.; Michel, H.; Safarian, S.: The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases. Frontiers in Chemistry (2023)

MPG.PuRe

6.

Zeitschriftenartikel

Schleker, E. S. M.; Buschmann, S.; Xie, H.; Welsch, S.; Michel, H.; Reinhart, C.: Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proceedings of the National Academy of Sciences of the United States of America 126 (43), S. 8646 - 8654 (2022)

MPG.PuRe

7.

Zeitschriftenartikel

Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Münke, C.; Robinson, C. V.; Hummer, G.; Xie, H. et al.; Michel, H.: Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism. The EMBO Journal 41 (18), e109990 (2022)

MPG.PuRe

8.

Zeitschriftenartikel

Meier-Credo, J.; Preiss, L.; Wüllenweber, I.; Resemann, A.; Nordmann, C.; Zabret, J.; Suckau, D.; Michel, H.; Nowacyk, M. M.; Meier, T. et al.; Langer, J. D.: Top-Down Identification and Sequence Analysis of Small Membrane Proteins Using MALDI-MS/MS. Journal of the American Society for Mass Spectrometry 33 (7), S. 1293 - 1302 (2022)

MPG.PuRe

9.

Zeitschriftenartikel

Zhao, J.; Hellwig, N.; Djahanschiri, B.; Khera, R.; Morgner, N.; Ebersberger, I.; Wang, J.; Michel, H.: Assembly and Functional Role of PACE Transporter PA2880 from Pseudomonas aeruginosa. Microbiology Spectrum 10 (2), e01453-21 (2022)

MPG.PuRe

10.

Zeitschriftenartikel

Grund, T. N.; Radloff, M.; Wu, D.; Goojani, H. G.; Witte, L. F.; Jösting, W.; Buschmann, S.; Müller, H.; Elamri, I.; Welsch, S. et al.; Schwalbe, H.; Michel, H.; Bald, D.; Safarian, S.: Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 118 (50), e2114013118 (2021)

MPG.PuRe

11.

Zeitschriftenartikel

Kolbe, F.; Safarian, S.; Piórek, Ż.; Welsch, S.; Müller, H.; Michel, H.: Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications 12, 6903 (2021)

MPG.PuRe

12.

Zeitschriftenartikel

Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)

MPG.PuRe

13.

Zeitschriftenartikel

Safarian, S.; Opel-Reading, H. K.; Wu, D.; Mehdipour, A. R.; Hards, K.; Harold, L. H.; Radloff, M.; Stewart, I.; Welsch, S.; Hummer, G. et al.; Cook, G. M.; Krause, K. L.; Michel, H.: The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications 12 (1), 5236 (2021)

MPG.PuRe

14.

Zeitschriftenartikel

Nikolaev, A.; Safarian, S.; Thesseling, A.; Wohlwend, D.; Friedrich, T.; Michel, H.; Kusumoto, T.; Sakamoto, J.; Melin, F.; Hellwig, P.: Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics 1862 (8), e148436 (2021)

MPG.PuRe

15.

Zeitschriftenartikel

Zhu, G.; Zeng, H.; Zhang, S.; Juli, J.; Tai, L.; Zhang, D.; Pang , X.; Zhang, Y.; Lam, S. M.; Zhu, Y. et al.; Peng, G.; Michel, H.; Sun, F.: The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English 60 (24), S. 13323 - 13330 (2021)

MPG.PuRe

16.

Zeitschriftenartikel

Wu, D.; Grund, T. N.; Welsch, S.; Mills, D.; Michel, M.; Safarian, S.; Michel, H.: Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America 117 (35), 202008111, S. 21281 - 21287 (2020)

MPG.PuRe

17.

Zeitschriftenartikel

Elamri, I.; Radloff, M.; Hohmann, K. F.; Nimbarte, V. D.; Nasiri, H. R.; Bolte, M.; Safarian, S.; Michel, H.; Schwalbe, H.: Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo₃ Ubiquinol Oxidase from Escherichia coli. ChemMedChem 15 (14), S. 1262 - 1271 (2020)

MPG.PuRe

18.

Zeitschriftenartikel

Zeng, H.; Zhu, G.; Zhang, S.; Li, X.; Martin, J.; Morgner, N.; Sun, F.; Peng, G.; Xie, H.; Michel, H.: Isolated Heme A Synthase from Aquifex aeolicus Is a Trimer. mBio 11 (3), e02615-19 (2020)

MPG.PuRe

19.

Zeitschriftenartikel

Zhu, G.; Zeng, H.; Zang, S.; Juli, J.; Pang, X.; Hoffman, J.; Zhang, Y.; Morgner, N.; Zhu, Y.; Peng, G. et al.; Michel, H.; Sun, F.: A 3.3 Å‐Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of its Thermal Stability. Angewandte Chemie, International Edition in English 59 (1), S. 343 - 351 (2020)

MPG.PuRe

20.

Zeitschriftenartikel

Lencina, A. M.; Koepke, J.; Preu, J.; Münke, C.; Gennis, R. B.; Michel, H.; Schurig-Briccio, L. A.: Characterization and X-ray structure of the NADH-dependent coenzyme A disulfide reductase from Thermus thermophilus. Biochimica et Biophysica Acta, Bioenergetics 1860 (11), e148080 (2019)

MPG.PuRe

21.

Zeitschriftenartikel

Safarian, S.; Hahn, A.; Mills, D.; Radloff, M.; Eisinger, M. L.; Nikolaev, A.; Meier-Credo, J.; Melin, F.; Miyoshi, H.; Gennis, R.B. et al.; Sakamoto, J.; Langer, J. D.; Hellwig, P.; Kühlbrandt, W.; Michel, H.: Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366 (6461), S. 100 - 104 (2019)

MPG.PuRe

22.

Zeitschriftenartikel

Zakrzewska, S.; Mehdipour, A. R.; Malviya, V. N.; Nonaka, T.; Koepke, J.; Muenke, C.; Hausner, W.; Hummer, G.; Safarian, S.; Michel, H.: Inward-facing conformation of a multidrug resistance MATE family transporter. Proceedings of the National Academy of Sciences of the United States of America 116 (25), S. 12275 - 12284 (2019)

MPG.PuRe

23.

Zeitschriftenartikel

Richter, M.; Moroniak, S. J.; Michel, H.: Identification of competitive inhibitors of the human taurine transporter TauT in a human kidney cell line. Pharmacological Reports 71 (1), S. 121 - 127 (2019)

MPG.PuRe

24.

Zeitschriftenartikel

Liu, W.; Liu, A.; Gao, H.; Wang, Q.; Wang, L.; Warkentin, E.; Rao, Z.; Michel, H.; Peng, G.: Structural properties of the peroxiredoxin AhpC2 from the hyperthermophilic eubacterium Aquifex aeolicus. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (12), S. 2797 - 2805 (2018)

MPG.PuRe

25.

Zeitschriftenartikel

Peng, G.; Meyer, B.; Sokolova, L.; Liu, W.; Bornemann, S.; Juli, J.; Zwicker, K.; Karas, M.; Brutschy, B.; Michel, H.: Identification and characterization two isoforms of NADH:ubiquinone oxidoreductase from the hyperthermophilic eubacterium Aquifex aeolicus. Biochimica et Biophysica Acta, Bioenergetics 1859 (5), S. 366 - 373 (2018)

MPG.PuRe

26.

Zeitschriftenartikel

Eisinger, M. L.; Nie, L.; Dörrbaum, A. R.; Langer, J. D.; Michel, H.: The Xenobiotic Extrusion Mechanism of the MATE Transporter NorM_PS from Pseudomonas stutzeri. Journal of Molecular Biology (London) 430 (9), S. 1311 - 1323 (2018)

MPG.PuRe

27.

Zeitschriftenartikel

Joedicke, L.; Mao, J.; Kuenze, G.; Reinhart, C.; Kalavacherla, T.; Jonker, H. R.A.; Richter, C.; Schwalbe, H.; Meiler, J.; Preu, J. et al.; Michel, H.; Glaubitz, C.: The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nature Chemical Biology 13 (3), S. 284 - 290 (2018)

MPG.PuRe

28.

Zeitschriftenartikel

Eisinger, M. L.; Dörrbaum, A. R.; Michel, H.; Padan, E.; Langer, J. D.: Ligand-induced conformational dynamics of the Escherichia coli Na⁺/H⁺ antiporter NhaA revealed by hydrogen/deuterium exchange mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 114 (44), S. 11691 - 11696 (2017)

MPG.PuRe

29.

Zeitschriftenartikel

Sommer, M.; Xie, H.; Michel, H.: Pseudomonas stutzeri as an alternative host for membrane proteins. Microbial Cell Factories 16, 157 (2017)

MPG.PuRe

30.

Zeitschriftenartikel

Kohlstädt, M.; Buschmann, S.; Langer, J. D.; Xie, H.; Michel, H.: Subunit CcoQ is involved in the assembly of the Cbb₃-type cytochrome c oxidases from Pseudomonas stutzeri ZoBell but not required for their activity. Biochimica et Biophysica Acta, Bioenergetics 1858 (3), S. 231 - 238 (2017)

MPG.PuRe

31.

Zeitschriftenartikel

Laiyin, N.; Grell, E.; Malviya, V. N.; Xie, H.; Wang, J.; Michel, H.: Identification of the High-affinity Substrate-binding Site of the Multidrug and Toxic Compound Extrusion (MATE) Family Transporter from Pseudomonas stutzeri. The Journal of Biological Chemistry 291 (30), S. 15503 - 15514 (2016)

MPG.PuRe

32.

Zeitschriftenartikel

Safarian, S.; Rajendran, C.; Müller, H.; Preu, J.; Langer, J. D.; Ovchinnikov, S.; Hirose, T.; Kusumoto, T.; Sakamoto, J.; Michel, H.: Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases. Science 352 (6285), S. 583 - 586 (2016)

MPG.PuRe

33.

Zeitschriftenartikel

Srinivasan, L.; Baars, T. L.; Fendler, K.; Michel, H.: Functional characterization of solute carrier (SLC) 26/sulfate permease (SulP) proteins in membrane mimetic systems. Biochimica et Biophysica Acta-Biomembranes 1858 (4), S. 698 - 705 (2016)

MPG.PuRe

34.

Zeitschriftenartikel

Kohlstädt, M.; Buschmann, S.; Xie, H.; Resemann, A.; Warkentin, E.; Langer, J. D.; Michel, H.: Identification and characterization of the novel subunit CcoM in the cbb₃-cytochrome c oxidase from Pseudomonas stutzeri ZoBell. mBio 7 (7), S. 1 - 9 (2016)

MPG.PuRe

35.

Zeitschriftenartikel

Joedicke, L.; Trenker, R.; Langer, J. D.; Michel, H.; Preu, J.: Cell-free synthesis of isotopically labelled peptide ligands for the functional characterization of G protein-coupled receptors. FEBS Open Bio 6 (1), S. 90 - 102 (2016)

MPG.PuRe

36.

Zeitschriftenartikel

Padan, E.; Michel, H.: NhaA: A Unique Structural Fold of Secondary Active Transporters. Israel Journal of Chemistry 55 (11/12), S. 1233 - 1239 (2015)

MPG.PuRe

37.

Zeitschriftenartikel

Kohlstädt, M.; von der Hocht, I.; Hilbers, F.; Thielmann, Y.; Michel, H.: Development of a Thermofluor assay for stability determination of membrane proteins using the Na⁺/H⁺antiporter NhaA and cytochrome c oxidase. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 71 (5), S. 1112 - 1122 (2015)

MPG.PuRe

38.

Zeitschriftenartikel

Meyer, T.; Melin, F.; Richter, O.-M.H.; Ludwig, B.; Kannt, A.; Müller, H.; Michel, H.; Hellwig, P.: Electrochemistry suggests proton access from the exit site to the binuclear center in Paracoccus denitrificans cytochrome c oxidase pathway variants. FEBS Letters 589 (5), S. 565 - 568 (2015)

MPG.PuRe

39.

Zeitschriftenartikel

Meyer, T.; Melin, F.; Xie, H.; von der Hocht, I.; Choi, S. K.; Noor, M. R.; Michel, H.; Gennis, R. B.; Soulimane, T.; Hellwig, P.: Evidence for Distinct Electron Transfer Processes in Terminal Oxidases from Different Origin by Means of Protein Film Voltammetry. Journal of the American Chemical Society 136 (31), S. 10821 - 11196 (2014)

MPG.PuRe

40.

Zeitschriftenartikel

Buschmann, S.; Richers, S.; Ermler, U.; Michel, H.: A decade of crystallization drops: Crystallization of the cbb₃ cytochrome c oxidase from Pseudomonas stutzeri. Protein Science 23 (4), S. 411 - 422 (2014)

MPG.PuRe

41.

Zeitschriftenartikel

Kaur, J.; Olkhova, E.; Malviya, V. N.; Grell, E.; Michel, H.: A L-Lysine Transporter of High Stereoselectivity of the Amino Acid-Polyamine-Organocation (APC) Superfamily PRODUCTION, FUNCTIONAL CHARACTERIZATION, AND STRUCTURE MODELING. The Journal of Biological Chemistry 289 (3), S. 1377 - 1387 (2014)

MPG.PuRe

42.

Zeitschriftenartikel

Xie, H.; Buschmann, S.; Langer, J. D.; Ludwig, B.; Michel, H.: Biochemical and Biophysical Characterization of the Two Isoforms of cbb₃-Type Cytochrome c Oxidase from Pseudomonas stutzeri. Journal of Bacteriology (Washington, DC) 196 (2), S. 472 - 482 (2014)

MPG.PuRe

43.

Zeitschriftenartikel

Zhang, C.; Allegretti, M.; Vonck, J.; Langer, J.; Marcia, M.; Peng, G.; Michel, H.: Production of fully assembled and active Aquifex aeolicus F1FO ATP synthase in Escherichia coli. Biochimica et Biophysica Acta (BBA) - General Subjects 1840 (1), S. 34 - 40 (2014)

MPG.PuRe

44.

Zeitschriftenartikel

Kozuch, J.; von der Hocht, I.; Hilbers, F.; Michel, H.; Weidinger, I. M.: Resonance Raman Characterization of the Ammonia-Generated Oxo Intermediate of Cytochrome c Oxidase from Paracoccus denitrificans. Biochemistry 52 (36), S. 6197 - 6202 (2013)

MPG.PuRe

45.

Zeitschriftenartikel

Ruehrer, S.; Michel, H.: Exploiting Leishmania tarentolae cell-free extracts for the synthesis of human solute carriers. Molecular Membrane Biology 30 (4), S. 288 - 302 (2013)

MPG.PuRe

46.

Zeitschriftenartikel

Zhang, C.; Marcia, M.; Langer, J. D.; Peng, G.; Michel, H.: Role of the N-terminal signal peptide in the membrane insertion of Aquifex aeolicus F₁F₀ ATP synthase c-subunit. The FEBS Journal 280 (14), S. 3425 - 3435 (2013)

MPG.PuRe

47.

Zeitschriftenartikel

Hilbers, F.; von der Hocht, I.; Ludwig, B.; Michel, H.: True wild type and recombinant wild type cytochrome c oxidase from Paracoccus denitrificans show a 20-fold difference in their catalase activity. Biochimica et Biophysica Acta, Bioenergetics 1827 (3), S. 319 - 327 (2013)

MPG.PuRe

48.

Zeitschriftenartikel

Kirchberg, K.; Michel, H.; Alexiev, U.: Exploring the entrance of proton pathways in cytochrome c oxidase from Paracoccus denitrificans: Surface charge, buffer capacity and redox-dependent polarity changes at the internal surface. Biochimica et Biophysica Acta, Bioenergetics 1827 (3), S. 276 - 284 (2013)

MPG.PuRe

49.

Zeitschriftenartikel

Jaehme, M.; Michel, H.: Evaluation of cell-free protein synthesis for the crystallization of membrane proteins – a case study of the glutamate transporter family from Staphylothermus marinus. The FEBS Journal 280 (4), S. 1112 - 1125 (2013)

MPG.PuRe

50.

Zeitschriftenartikel

Wang, T.; Langer, J. D.; Peng, G.; Michel, H.: Isolation, functional characterization and crystallization of Aq_1259, an outer membrane protein with porin features, from Aquifex aeolicus. Biochimica et Biophysica Acta-Proteins and Proteomics 1824 (12), S. 1358 - 1365 (2012)

MPG.PuRe

51.

Zeitschriftenartikel

Goswami, D.; Kaur, J.; Surade, S.; Grell, E.; Michel, H.: Heterologous production and functional and thermodynamic characterization of cation diffusion facilitator (CDF) transporters of mesophilic and hyperthermophilic origin. Biological Chemistry 393 (7), S. 617 - 629 (2012)

MPG.PuRe

52.

Zeitschriftenartikel

Thielmann, Y.; Koepke, J.; Michel, H.: The ESFRI Instruct Core Centre Frankfurt: automated high-throughput crystallization suited for membrane proteins and more. Journal of Structural and Functional Genomics, S. 63 - 69 (2012)

MPG.PuRe

53.

Zeitschriftenartikel

Rycovska, A.; Hatahet, L.; Fendler, K.; Michel, H.: The nitrite transport protein NirC from Salmonella typhimurium is a nitrite/proton antiporter. Biochimica et Biophysica Acta-Biomembranes 1818 (5), S. 1342 - 1350 (2012)

MPG.PuRe

54.

Zeitschriftenartikel

Michel, H.: The Nonsense of Biofuels. Angewandte Chemie, International Edition in English 51 (11), S. 2516 - 2518 (2012)

MPG.PuRe

55.

Zeitschriftenartikel

Kirchberg, K.; Michel, H.; Alexiev, U.: Net Proton Uptake Is Preceded by Multiple Proton Transfer Steps upon Electron Injection into Cytochrome c Oxidase. The Journal of Biological Chemistry 287 (11), S. 8187 - 8193 (2012)

MPG.PuRe

56.

Zeitschriftenartikel

Gao, Y.; Meyer, B.; Sokolova, L.; Zwicker, K.; Karas, M.; Brutschy, B.; Peng, G.; Michel, H.: Heme-copper terminal oxidase using both cytochrome c and ubiquinol as electron donors. Proceedings of the National Academy of Sciences of the United States of America 109 (9), S. 3275 - 3280 (2012)

MPG.PuRe

57.

Zeitschriftenartikel

von der Hocht, I.; van Wonderen, J. H.; Hilbers, F.; Angerer, H.; MacMillan, F.; Michel, H.: Interconversions of P and F intermediates of cytochrome c oxidase from Paracoccus denitrificans. Proceedings of the National Academy of Sciences of the United States of America 108 (10), S. 3964 - 3969 (2011)

MPG.PuRe

58.

Zeitschriftenartikel

Hedderich, T.; Marcia, M.; Köpke, J.; Michel, H.: PICKScreens, A New Database for the Comparison of Crystallization Screens for Biological Macromolecules. Crystal Growth & Design 11 (2), S. 488 - 491 (2011)

MPG.PuRe

59.

Zeitschriftenartikel

MacMillan, F.; Kacprzak, S.; Hellwig, P.; Grimaldi, S.; Michel, H.; Kaupp, M.: The high-affinity Q_H binding site in quinol oxidase as studied by DONUT-HYSCORE spectroscopy and density functional theory. Faraday Discussions 148, S. 315 - 344 (2011)

MPG.PuRe

60.

Zeitschriftenartikel

Marcia, M.; Langer, J. D.; Parcej, D.; Vogel, V.; Peng, G.; Michel, H.: Characterizing a monotopic membrane enzyme. Biochemical, enzymatic and crystallization studies on Aquifex aeolicus sulfide:quinone oxidoreductase. Biochimica et Biophysica Acta-Biomembranes 1798 (11), S. 2114 - 2123 (2010)

MPG.PuRe

61.

Zeitschriftenartikel

Buschmann, S.; Warkentin, E.; Xie, H.; Langer, J. D.; Ermler, U.; Michel, H.: The Structure of cbb₃ Cytochrome Oxidase Provides Insights into Proton Pumping. Science 329 (5989), S. 327 - 330 (2010)

MPG.PuRe

62.

Zeitschriftenartikel

Rajendran, C.; Ermler, U.; Ludwig, B.; Michel, H.: Structure at 1.5 Å resolution of cytochrome c₅₅₂ with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D66 (7), S. 850 - 854 (2010)

MPG.PuRe

63.

Zeitschriftenartikel

Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: A new structure-based classification of sulfide:quinone oxidoreductases. Proteins: Structure, Function, and Bioinformatics 78 (5), S. 1073 - 1083 (2010)

MPG.PuRe

64.

Zeitschriftenartikel

Clason, T.; Ruiz, T.; Schägger, H.; Peng, G.; Zickermann, V.; Brandt, U.; Michel, H.; Radermacher, M.: The structure of eukaryotic and prokaryotic complex I. Journal of Structural Biology 169 (1), S. 81 - 88 (2010)

MPG.PuRe

65.

Zeitschriftenartikel

Baier, J.; Gabrielsen, M.; Oellerich, S.; Michel, H.; van Heel, M.; Cogdell, R. J.; Köhler, J.: Spectral Diffusion and Electron-Phonon Coupling of the B800 BChl a Molecules in LH2 Complexes from Three Different Species of Purple Bacteria. Biophysical Journal 97 (9), S. 2604 - 2612 (2009)

MPG.PuRe

66.

Zeitschriftenartikel

Olkhova, E.; Kozachkov, L.; Padan, E.; Michel, H.: Combined computational and biochemical study reveals the importance of electrostatic interactions between the ‘‘pH sensor’’ and the cation binding site of the sodium/proton antiporter NhaA of Escherichia coli. Proteins: Structure, Function, and Bioinformatics 76 (3), S. 548 - 559 (2009)

MPG.PuRe

67.

Zeitschriftenartikel

Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proceedings of the National Academy of Sciences of the United States of America 106 (24), S. 9625 - 9630 (2009)

MPG.PuRe

68.

Zeitschriftenartikel

Koepke, J.; Olkhova, E.; Angerer, H.; Müller, H.; Peng, G.; Michel, H.: High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways. Biochimica et Biophysica Acta, Bioenergetics 1787 (6), S. 635 - 645 (2009)

MPG.PuRe

69.

Zeitschriftenartikel

Xia, H.; Liu, L.; Reinhart, C.; Michel, H.: Heterologous expression of human Neuromedin U receptor 1 and its subsequent solubilization and purification. Biochimica et Biophysica Acta-Biomembranes 1778 (10), S. 2203 - 2209 (2008)

MPG.PuRe

70.

Zeitschriftenartikel

Rimon, A.; Hunte, C.; Michel, H.; Padan, E.: Epitope Mapping of Conformational Monoclonal Antibodies Specific to NhaA Na⁺/H⁺ antiporter: Structural and Functional Implications. Journal of Molecular Biology (London) 379 (3), S. 471 - 481 (2008)

MPG.PuRe

71.

Zeitschriftenartikel

Lopez, J. J.; Shukla, A. K.; Reinhart, C.; Schwalbe, H.; Michel, H.; Glaubitz, C.: The Structure of the Neuropeptide Bradykinin Bound to the Human G-Protein Coupled Receptor Bradykinin B2 as Determined by Solid-State NMR Spectroscopy. Angewandte Chemie 120 (9), S. 1692 - 1695 (2008)

MPG.PuRe

72.

Zeitschriftenartikel

Dürr, K. L.; Koepke, J.; Hellwig, P.; Müller, H.; Angerer, H.; Peng, G.; Olkhova, E.; Richter, O.-M. H.; Ludwig, B.; Michel, H.: A D-Pathway Mutation Decouples the Paracoccus denitrificans Cytochrome c Oxidase by Altering the Side-Chain Orientation of a Distant Conserved Glutamate. Journal of Molecular Biology (London) 384 (4), S. 865 - 877 (2008)

MPG.PuRe

73.

Zeitschriftenartikel

Roy, A.; Shukla, A. K.; Haase, W.; Michel, H.: Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors. Biological Chemistry Hoppe-Seyler 389 (1), S. 69 - 78 (2008)

MPG.PuRe

74.

Zeitschriftenartikel

Chillakuri, C. R.; Reinhart, C.; Michel, H.: C-terminal truncated cannabinoid receptor 1 co-expressed with G protein trimer in Sf9 cells exist in a precoupled state and show constitutive activity. The FEBS Journal 274 (23), S. 6106 - 6115 (2007)

MPG.PuRe

75.

Zeitschriftenartikel

Srinivasan, V.; Netz, D. J. A.; Webert, H.; Mascarenhas, J.; Plerik, A. J.; Michel, H.; Lill, R.: Structure of the Yeast WD40 Domain Protein Cia1, a Component Acting Late in Iron-Sulfur Protein Biogenesis. Structure 15 (10), S. 1246 - 1257 (2007)

MPG.PuRe

76.

Zeitschriftenartikel

Wedemeyer, U.; Peng, G.; Michel, H.; Hartung, K.: Protein AQ_1862 from the Hyperthermophilic Bacterium Aquifex aeolicus is a Porin and Contains Two Conductance Pathways of Different Selectivity. Biophysical Journal 93 (8), S. 2667 - 2677 (2007)

MPG.PuRe

77.

Zeitschriftenartikel

Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Heterologous expression and characterization of the recombinant bradykinin B₂ receptor using the methylotrophic yeast Pichia pastoris. Protein Expression and Purification 55 (1), S. 1 - 8 (2007)

MPG.PuRe

78.

Zeitschriftenartikel

Klammt, C.; Srivastava, A.; Eifler, N.; Junge, F.; Beyermann, M.; Schwarz, D.; Michel, H.; Doetsch, V.; Bernhard, F.: Functional analysis of cell-free produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation. The FEBS Journal 274 (13), S. 3257 - 3269 (2007)

MPG.PuRe

79.

Zeitschriftenartikel

Olkhova, E.; Padan, E.; Michel, H.: The Influence of Protonation States on the Dynamics of the NhaA Antiporter from Escherichia coli. Biophysical Journal 92 (11), S. 3784 - 3791 (2007)

MPG.PuRe

80.

Zeitschriftenartikel

Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. The International Journal of Biochemistry & Cell Biology 39 (5), S. 931 - 942 (2007)

MPG.PuRe

81.

Zeitschriftenartikel

Peng, G.; Bostina, M.; Radermacher, M.; Rais, I.; Karas, M.; Michel, H.: Biochemical and electron microscopic characterization of the F₁F₀ ATP Synthase from the hyperthermophilic eubacterium Aquifex aeolicus. FEBS Letters 580 (25), S. 5934 - 5940 (2006)

MPG.PuRe

82.

Zeitschriftenartikel

Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Functional Overexpression and Characterization of Human Bradykinin Subtype 2 Receptor in Insect Cells Using the Baculovirus System. Journal of Cellular Biochemistry 99 (3), S. 868 - 877 (2006)

MPG.PuRe

83.

Zeitschriftenartikel

Shukla, A. K.; Reinhart, C.; Michel, H.: Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells. Biochemical and Biophysical Research Communications 349 (1), S. 6 - 14 (2006)

MPG.PuRe

84.

Zeitschriftenartikel

Screpanti, E.; Padan, E.; Rimon, A.; Michel, H.; Hunte, C.: Crucial Steps in the Structure Determination of the Na⁺/H⁺ Antiporter NhaA in its Native Conformation. Journal of Molecular Biology (London) 362 (2), S. 192 - 202 (2006)

MPG.PuRe

85.

Zeitschriftenartikel

Surade, S.; Klein, M.; Stolt-Bergner, P. C.; Muenke, C.; Roy, A.; Michel, H.: Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Science 15 (9), S. 2178 - 2189 (2006)

MPG.PuRe

86.

Zeitschriftenartikel

Shukla, A. K.; Reinhart, C.; Michel, H.: Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells. FEBS Letters 580 (17), S. 4261 - 4265 (2006)

MPG.PuRe

87.

Zeitschriftenartikel

Lundstrom, K.; Wagner, R.; Reinhart, C.; Desmyter, A.; Cherouati, N.; Magnin, T.; Zeder-Lutz, G.; Courtot, M.; Prual, C.; André, N. et al.; Hassaine, G.; Michel, H.; Cambillau, C.; Pattus, F.: Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. Journal of Structural and Functional Genomics 7 (2), S. 77 - 91 (2006)

MPG.PuRe

88.

Zeitschriftenartikel

André, N.; Cherouati, N.; Prual, C.; Steffan, T.; Zeder-Lutz, G.; Magnin, T.; Pattus, F.; Michel, H.; Wagner, R.; Reinhart, C.: Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Science 15 (5), S. 1115 - 1126 (2006)

MPG.PuRe

89.

Zeitschriftenartikel

Shukla, A. K.; Haase, W.; Reinhart, C.; Michel, H.: Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system. Biological Chemistry 387 (5), S. 569 - 576 (2006)

MPG.PuRe

90.

Zeitschriftenartikel

Farver, O.; Grell, E.; Ludwig, B.; Michel, H.; Pecht, I.: Rates and Equilibrium of Cu_A to Heme a Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase. Biophysical Journal 90, S. 2131 - 2137 (2006)

MPG.PuRe

91.

Zeitschriftenartikel

Olkhova, E.; Hunte, C.; Screpanti, E.; Padan, E.; Michel, H.: Multiconformation continuum electrostatics analysis of the NhaA Na⁺/H⁺ antiporter of Escherichia coli with functional implications. Proceedings of the National Academy of Sciences of the United States of America 103 (8), S. 2629 - 2634 (2006)

MPG.PuRe

92.

Zeitschriftenartikel

MacMillan, F.; Budiman, K.; Angerer, H.; Michel, H.: The role of tryptophan 272 in the Paracoccus denitrificans cytochrome c oxidase. FEBS Letters 580 (5), S. 1345 - 1349 (2006)

MPG.PuRe

93.

Zeitschriftenartikel

Olkhova, E.; Helms, V.; Michel, H.: Titration Behavior of Residues at the Entrance of the D-Pathway of Cytochrome c Oxidase from Paracoccus denitrificans Investigated by Continuum Electrostatic Calculations. Biophysical Journal 89 (4), S. 2324 - 2331 (2005)

MPG.PuRe

94.

Zeitschriftenartikel

Hunte, C.; Screpanti, E.; Venturi, M.; Rimon, A.; Padan, E.; Michel, H.: Structure of a Na⁺/H⁺ antiporter and insights into mechanism of action and regulation by pH. Nature 435 (7046), S. 1197 - 1202 (2005)

MPG.PuRe

95.

Zeitschriftenartikel

Hofmann, C.; Michel, H.; van Heel, M.; Köhler, J.: Multivariate Analysis of Single-Molecule Spectra: Surpassing Spectral Diffusion. Physical Review Letters 94 (19), 195501 (2005)

MPG.PuRe

96.

Zeitschriftenartikel

Barleben, L.; Ma, X.; Koepke, J.; Peng, G.; Michel, H.; Stöckigt, J.: Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Proteins & Proteomics, S. 89 - 92 (2005)

MPG.PuRe

97.

Zeitschriftenartikel

Srinivasan, V.; Rajendran, C.; Sousa, F. L.; Melo, A. M.P.; Saraiva, L. M.; Pereira, M. M.; Santana, M.; Teixeira, M.; Michel, H.: Structure at 1.3 Å Resolution of Rhodothermus marinus caa₃ Cytochrome c Domain. Journal of Molecular Biology (London) 345 (5), S. 1047 - 1057 (2005)

MPG.PuRe

98.

Zeitschriftenartikel

Ma, X.; Koepke, J.; Fritzsch, G.; Diem, R.; Kutchan, T. M.; Michel, H.; Stöckigt, J.: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochimica et Biophysica Acta-Proteins and Proteomics 1702, S. 121 - 124 (2004)

MPG.PuRe

99.

Zeitschriftenartikel

Budiman, K.; Kannt, A.; Lyubenova, S.; Richter, O.-M.; Ludwig, B.; Michel, H.; MacMillan, F.: Tyrosine-167: The Origin of the Radical Species Observed in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide in Paracoccus denitrificans. Biochemistry 43 (37), S. 11709 - 11716 (2004)

MPG.PuRe

100.

Zeitschriftenartikel

Ma, X.; Koepke, J.; Bayer, A.; Linhard, V.; Fritzsch, G.; Zhang, B.; Michel, H.; Stöckigt, J.: Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochimica et Biophysica Acta-Proteins and Proteomics 1701 (1-2), S. 129 - 132 (2004)

MPG.PuRe