Publikationen der Abteilung für Strukturbiologie

Buckel, W.; Ermler, U.; Vonck, J.; Fritz, G.; Steuber, J.: The RNF/NQR redox pumps: a versatile system for energy transduction in bacteria and archaea. Applied Microbiology and Biotechnology 109, 148 (2025)

Lafargue, E.; Duneau, J.-P.; Buzhinsky, N.; Ornelas, P.; Ortega, A.; Ravishankar, V.; Sturgis, J.; Casuso, I.; Bergdoll, L.: Membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper. Communications Biology 8, 936 (2025)

Stautz, J.; Griwatz, D.; Kaltwasser, S.; Mehdipour, A. R.; Ketter, S.; Thiel, C.; Wunnicke, D.; Schrecker, M.; Mills, D. J.; Hummer, G. et al.; Vonck, J.; Hänelt, I.: A short intrinsically disordered region at KtrB’s N-terminus facilitates allosteric regulation of K⁺ channel KtrAB. Nature Communications 16, 4252 (2025)

Kühlbrandt, W.; Carreira, L. A. M.; Yildiz, Ö.: Cryo-EM of Mitochondrial Complex I and ATP Synthase. Annual Review of Biophysics 54, S. 209 - 226 (2025)

Lee, Y.; Jin, C.; Ohgaki, R.; Xu, M.; Ogasawara, S.; Warshamanage, R.; Yamashita, K.; Murshudov, G.; Nureki, O.; Murata, T. et al.; Kanai, Y.: Structural basis of anticancer drug recognition and amino acid transport by LAT1. Nature Communications 16, 1635 (2025)

Introini, B.; Hahn, A.; Kühlbrandt, W.: Cryo-EM structure of the NDH-PSI-LHCI supercomplex from Spinacia oleracea. Nature Structural & Molecular Biology (2025)

Periasamy, A.; Ornelas, P.; Bausewein, T.; Mitchell, N.; Zhao, J.; Quinn, L. M.; Kuehlbrandt, W.; Gulbis, J. M.: Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM. IUCrJ 12 (1) (2025)

Wilm, M.: Nanoelectrospray based synthesis of large, transportable membranes with integrated membrane proteins. Scientific Reports 14, 25192 (2024)

Dietrich, L.; Agip, A.-N. A.; Kunz, C.; Schwarz, A.; Kühlbrandt, W.: In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells. Science 385 (6713), S. 1086 - 1090 (2024)

Schneider, S.; Kühlbrandt, W.; Yildiz, Ö.: Complementary structures of the yeast phosphate transporter Pho90 provide insights into its transport mechanism. Structure 32 (7), S. 979 - 988.e4 (2024)

Adolph, C.; Cheung, C.-Y.; McNeil, M. B.; Jowsey, W. J.; Williams, Z. C.; Hards, K.; Harold, L. K.; Aboelela, A.; Bujaroski, R. S.; Buckley, B. J. et al.; Tyndall, J. D. A.; Li, Z.; Langer, J. D.; Preiss, L.; Meier, T.; Steyn, A. J. C.; Rhee, K. Y.; Berney, M.; Kelso, M. J.; Cook, G. M.: A dual-targeting succinate dehydrogenase and F₁F_o-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. Cell Chemical Biology 31, S. 683 - 698.e7 (2024)

Aziz, I.; Kayastha, K.; Kaltwasser, S.; Vonck, J.; Welsch, S.; Murphy, B. J.; Kahnt, J.; Wu, D.; Wagner, T.; Shima, S. et al.; Ermler, U.: Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis. PNAS 121 (14), e2315568121 (2024)

Lasham, J.; Djurabekova, A.; Zickermann, V.; Vonck, J.; Sharma, V.: Role of Protonation States in the Stability of Molecular Dynamics Simulations of High-Resolution Membrane Protein Structures. The Journal of Physical Chemistry B 128 (10), S. 2304 - 2316 (2024)

Laube, E.; Schiller, J.; Zickermann, V.; Vonck, J.: Using cryo-EM to understand the assembly pathway of respiratory complex I. Acta Crystallographica Section D: Structural Biology 80, S. 159 - 173 (2024)

Centola, M.; Poppleton, E.; Ray, S.; Centola, M.; Welty, R.; Valero, J.; Walter, N. G.; Šulc, P.; Famulok, M.: A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower. Nature Nanotechnology 19 (2), S. 226 - 236 (2024)

Gewering, T.; Waghray, D.; Parey, K.; Jung, H.; Tran, N. N. B.; Zapata, J.; Zhao, P.; Chen, H.; Januliene, D.; Hummer, G. et al.; Urbatsch, I.; Moeller, A.; Zhang, Q.: Tracing the substrate translocation mechanism in P-glycoprotein. eLife 12, RP90174 (2024)

Braun, H.-P.; Klusch, N.: Promotion of oxidative phosphorylation by complex I-anchored carbonic anhydrases? Trends in Plant Science 29 (1), S. 64 - 71 (2024)

Lasham, J.; Djurabekova, A.; Kolypetris, G.; Zickermann, V.; Vonck, J.; Sharma, V.: Assessment of amino acid charge states based on cryo-electron microscopy and molecular dynamics simulations of respiratory complex I. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1866 (1), 149512 (2024)

Hau, J.-L.; Kaltwasser, S.; Muras, V.; Casutt, M. S.; Vohl, G.; Claußen, B.; Steffen, W.; Leitner, A.; Bill, E.; Cutsail, G. E. et al.; DeBeer, S.; Vonck, J.; Steuber, J.; Fritz, G.: Conformational coupling of redox-driven Na⁺-translocation in Vibrio cholerae NADH:quinone oxidoreductase. Nature Structural & Molecular Biology 30 (11), S. 1686 - 1694 (2023)

Ornelas, P.; Bausewein, T.; Martin, J.; Morgner, N.; Nussberger, S.; Kühlbrandt, W.: Two conformations of the Tom20 preprotein receptor in the TOM holo complex. Proceedings of the National Academy of Sciences of the United States of America 120 (34), e2301447120 (2023)