Publikationen des Max-Planck-Institutes für Biophysik

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Zeitschriftenartikel (86)

2021
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Zila, V.; Margiotta, E.; Turoňová, B.; Müller, T. G.; Zimmerli, C. E.; Mattei, S.; Allegretti, M.; Börner, K.; Rada, J.; Müller, B. et al.; Lusic, M.; Kräusslich, H.-G.; Beck, M.: Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell 184 (2021)
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Bárcena, M.; Barnes, C. O.; Beck, M.; Bjorkman, P. J.; Canard, B.; Gao, G. F.; Gao, Y.; Hilgenfeld, R.; Hummer, G.; Patwardhan, A. et al.; Santoni, G.; Saphire, E. O.; Schaffitzel, C.; Schendel, S. L.; Smith, J. L.; Thorn, A.; Veesler, D.; Zhang, P.; Zhou, Q.: Structural biology in the fight against COVID-19. Nature Structural and Molecular Biology 28 (1), S. 2 - 7 (2021)
2020
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Allegretti, M.; Zimmerli, C. E.; Rantos, V.; Wilfling, F.; Ronchi, P.; Fung, H. K. H.; Lee, C.-W.; Hagen, W.; Turoňová, B.; Karius, K. et al.; Börmel, M.; Zhang, X.; Müller, C. W.; Schwab, Y.; Mahamid, J.; Pfander, B.; Kosinski, J.; Beck, M.: In-cell architecture of the nuclear pore and snapshots of its turnover. Nature 586 (7831), S. 796 - 800 (2020)
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Zhou, Y.; Kastritis, P. L.; Dougherty, S. E.; Bouvette, J.; Hsu, A. L.; Burbaum, L.; Mosalaganti, S.; Pfeffer, S.; Hagen, W. J. H.; Förster, F. et al.; Borgnia, M. J.; Vogel, C.; Beck, M.; Bartesaghi, A.; Silva, G. M.: Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proceedings of the National Academy of Sciences of the United States of America 117 (36), S. 22157 - 22166 (2020)
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Turoňová, B.; Sikora, M.; Schürmann, C.; Hagen, W. J. H.; Welsch, S.; Blanc, F. E. C.; von Bülow, S.; Gecht, M.; Bagola, K.; Hörner, C. et al.; van Zandbergen, G.; Landry, J.; de Azevedo, N. T. D.; Mosalaganti, S.; Schwarz, A.; Covino, R.; Mühlebach, M. D.; Hummer, G.; Krijnse Locker, J.; Beck, M.: In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science, abd5223 (2020)
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Lee, B.-G.; Merkel, F.; Allegretti, M.; Hassler, M.; Cawood, C.; Lecomte, L.; O'Reilly, F. J.; Sinn, L. R.; Gutierrez-Escribano, P.; Kschonsak, M. et al.; Bravo, S.; Nakane, T.; Rappsilber, J.; Aragon, L.; Beck, M.; Löwe, J.; Haering, C. H.: Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nature Structural and Molecular Biology 27 (8), S. 743 - 751 (2020)
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Buczak, K.; Kirkpatrick, J. M.; Truckenmueller, F.; Santinha, D.; Ferreira, L.; Roessler, S.; Singer, S.; Beck, M.; Ori, A.: Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. Nature Protocols 15 (2020)
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Turoňová, B.; Hagen, W. J. H.; Obr, M.; Mosalaganti, S.; Beugelink, J. W.; Zimmerli, C. E.; Kräusslich, H.-G.; Beck, M.: Benchmarking tomographic acquisition schemes for high-resolution structural biology. Nature Communications 11, 876 (2020)
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Fürsch, J.; Kammer, K.-M.; Kreft, S. G.; Beck, M.; Stengel, F.: Proteome-Wide Structural Probing of Low-Abundant Protein Interactions by Cross-Linking Mass Spectrometry. Analytical Chemistry 92 (5), S. 4016 - 4022 (2020)
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Lee, C.-W.; Wilfling, F.; Ronchi, P.; Allegretti, M.; Mosalaganti, S.; Jentsch, S.; Beck, M.; Pfander, B.: Selective autophagy degrades nuclear pore complexes. Nature Cell Biology 22 (2), S. 159 - 166 (2020)
2019
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Guo, T.; Luna, A.; Rajapakse, V. N.; Koh, C. C.; Wu, Z.; Liu, W.; Sun, Y.; Gao, H.; Menden, M. P.; Xu, C. et al.; Calzone, L.; Martignetti, L.; Auwerx, C.; Buljan, M.; Banaei-Esfahani, A.; Ori, A.; Iskar, M.; Gillet, L.; Bi, R.; Zhang, J.; Zhang, H.; Yu, C.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Zhang, Q.; Zhu, Y.; Wild, P. J.; Garnett, M. J.; Bork, P.; Beck, M.; Liu, K.; Saez-Rodriguez, J.; Elloumi, F.; Reinhold, W. C.; Sander, C.; Pommier, Y.; Aebersold, R.: Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines. iScience 21, S. 664 - 680 (2019)
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Hampoelz, B.; Schwarz, A.; Ronchi, P.; Bragulat-Teixidor, H.; Tischer, C.; Gaspar, I.; Ephrussi, A.; Schwab, Y.; Beck, M.: Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell 179 (3), S. 671 - 686.e17 (2019)
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Schwarz, A.; Beck, M.: The Benefits of Cotranslational Assembly: A Structural Perspective. Trends in Cell Biology 29 (10), S. 791 - 803 (2019)
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Romanov, N.; Kuhn, M.; Aebersold, R.; Ori, A.; Beck, M.; Bork, P.: Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals. Cell 177 (5), S. 1308 - 1318 (2019)
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Holzer, K.; Ori, A.; Cooke, A.; Dauch, D.; Drucker, E.; Riemenschneider, P.; Andres-Pons, A.; DiGuilio, A. L.; Mackmull, M.-T.; Baßler, J. et al.; Roessler, S.; Breuhahn, K.; Zender, L.; Glavy, J. S.; Dombrowski, F.; Hurt, E.; Schirmacher, P.; Beck, M.; Singer, S.: Nucleoporin Nup155 is part of the p53 network in liver cancer. Nature Communications 10, 2147 (2019)
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Hampoelz, B.; Andres-Pons, A.; Kastritis, P.; Beck, M.: Structure and Assembly of the Nuclear Pore Complex. Annual Review of Biophysics 48, S. 515 - 536 (2019)
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Thaller, D. J.; Allegretti, M.; Borah, S.; Ronchi, P.; Beck, M.; Lusk, C. P.: An ESCRT-LEM Protein Surveillance System Is Poised to Directly Monitor the Nuclear Envelope and Nuclear Transport System. eLife 8, e45284 (2019)
2018
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Beck, M.; Mosalaganti, S.; Kosinski, J.: From the resolution revolution to evolution: structural insights into the evolutionary relationships between vesicle coats and the nuclear pore. Current Opinion in Structural Biology 52, S. 32 - 40 (2018)
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Kehrer, J.; Kuss, C.; Andres-Pons, A.; Reustle, A.; Dahan, N.; Devos, D.; Kudryashev, M.; Beck, M.; Mair, G. R.; Frischknecht, F.: Nuclear Pore Complex Components in the Malaria Parasite Plasmodium Berghei. Scientific Reports 8, 11249 (2018)
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Parca, L.; Beck, M.; Bork, P.; Ori, A.: Quantifying compartment-associated variations of protein abundance in proteomics data. Molecular Systems Biology 14 (7), e8131 (2018)
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Mosalaganti, S.; Kosinski, J.; Albert, S.; Schaffer, M.; Strenkert, D.; Salomé, P. A.; Merchant, S. S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D. et al.; Beck, M.: In situ architecture of the algal nuclear pore complex. Nature Communications 9 (1), 2361 (2018)
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Becher, I.; Andrés-Pons, A.; Romanov, N.; Stein, F.; Schramm, M.; Baudin, F.; Helm, D.; Kurzawa, N.; Mateus, A.; Mackmull, M.-T. et al.; Typas, A.; Müller, C. W.; Bork, P.; Beck, M.; Savitski, M. M.: Pervasive Protein Thermal Stability Variation During the Cell Cycle. Cell 173 (6), S. 1495 - 1507 (2018)
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Buczak, K.; Ori, A.; Kirkpatrick, J. M.; Holzer, K.; Dauch, D.; Roessler, S.; Endris, V.; Lasitschka, F.; Parca, L.; Schmidt, A. et al.; Zender, L.; Schirmacher, P.; Krijgsveld, J.; Singer, S.; Beck, M.: Spatial Tissue Proteomics Quantifies Inter- And Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). Molecular and Cellular Proteomics 17 (4), S. 810 - 825 (2018)
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Mathieson, T.; Franken, H.; Kosinski, J.; Kurzawa, N.; Zinn, N.; Sweetman, G.; Poeckel, D.; Ratnu, V. S.; Schramm, M.; Becher, I. et al.; Steidel, M.; Noh, K.-M.; Bergamini, G.; Beck, M.; Bantscheff, M.; Savitski, M. M.: Systematic analysis of protein turnover in primary cells. Nature Communications 9, 689 (2018)
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Otsuka, S.; Steyer, A. M.; Schorb, M.; Hériché, J.-K.; Hossain, M. J.; Sethi, S.; Kueblbeck, M.; Schwab, Y.; Beck, M.; Ellenberg, J.: Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings. Nature Structural and Molecular Biology 25 (1), S. 21 - 28 (2018)
2017
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Albert, S.; Schaffer, M.; Beck, F.; Mosalaganti, S.; Asano, S.; Thomas, H. F.; Plitzko, J. M.; Beck, M.; Baumeister, W.; Engel, B. D.: Proteasomes tether to two distinct sites at the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America 114 (52), S. 13726 - 13731 (2017)
Zeitschriftenartikel
Mackmull, M.-T.; Klaus, B.; Heinze, I.; Chokkalingam, M.; Beyer, A.; Russell, R. B.; Ori, A.; Beck, M.: Landscape of nuclear transport receptor cargo specificity. Molecular Systems Biology 13 (12), 962 (2017)
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Beck, M.; Schirmacher, P.; Singer, S.: Alterations of the nuclear transport system in hepatocellular carcinoma - New basis for therapeutic strategies. Journal of Hepatology 67 (5), S. 1051 - 1061 (2017)
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Teimer, R.; Kosinski, J.; von Appen, A.; Beck, M.; Hurt, E.: A Short Linear Motif in Scaffold Nup145C Connects Y-complex With Pre-Assembled Outer Ring Nup82 Complex. Nature Communications 8, 1107 (2017)
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Sadian, Y.; Tafur, L.; Kosinski, J.; Jakobi, A. J.; Wetzel, R.; Buczak, K.; Hagen, W. J.; Beck, M.; Sachse, C.; Müller, C. W.: Structural Insights Into Transcription Initiation by Yeast RNA Polymerase I. The EMBO Journal 36 (18), S. 2698 - 2709 (2017)
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Kastritis, P. L.; O'Reilly, F. J.; Bock, T.; Li, Y.; Rogon, M. Z.; Buczak, K.; Romanov, N.; Betts, M. J.; Bui, K. H.; Hagen, W. J. et al.; Hennrich, M. L.; Mackmull, M.-T.; Rappsilber, J.; Russell, R. B.; Bork, P.; Beck, M.; Gavin, A.-C.: Capturing protein communities by structural proteomics in a thermophilic eukaryote. Molecular Systems Biology 13 (7), 936 (2017)
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Beck, M.; Hurt, E.: The nuclear pore complex: understanding its function through structural insight. Nature Reviews Molecular Cell Biology 18 (2), S. 73 - 89 (2017)
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Dauden, M. I.; Kosinski, J.; Kolaj-Robin, O.; Desfosses, A.; Ori, A.; Faux, C.; Hoffmann, N. A.; Onuma, O. F.; Breunig, K. D.; Beck, M. et al.; Sachse, C.; Séraphin, B.; Glatt, S.; Müller, C. W.: Architecture of the yeast Elongator complex. EMBO Journal 18 (2), S. 264 - 279 (2017)
2016
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Scharaw, S.; Iskar, M.; Ori, A.; Boncompain, G.; Laketa, V.; Poser, I.; Lundberg, E.; Perez, F.; Beck, M.; Bork, P. et al.; Pepperkok, R.: The Endosomal Transcriptional Regulator RNF11 Integrates Degradation and Transport of EGFR. The Journal of Cell Biology: JCB 215 (4), S. 543 - 558 (2016)
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Kiosze-Becker, K.; Ori, A.; Gerovac, M.; Heuer, A.; Nürenberg-Goloub, E.; Rashid, U. J.; Becker, T.; Beckmann, R.; Beck, M.; Tampé, R.: Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry. Nature Communications 7, 13248 (2016)
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Beck, M.; Baumeister, W.: Cryo-Electron Tomography: Can It Reveal the Molecular Sociology of Cells in Atomic Detail? Trends in Cell Biology 26 (11), S. 825 - 837 (2016)
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Otsuka, S.; Bui, K. H.; Schorb, M.; Hossain, M. J.; Politi, A. Z.; Koch, B.; Eltsov, M.; Beck, M.; Ellenberg, J.: Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope. eLife 5, e19071 (2016)
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Hampoelz, B.; Mackmull, M.-T.; Machado, P.; Ronchi, P.; Bui, K. H.; Schieber, N.; Santarella-Mellwig, R.; Necakov, A.; Andrés-Pons, A.; Philippe, J. M. et al.; Lecuit, T.; Schwab, Y.; Beck, M.: Pre-assembled Nuclear Pores Insert Into the Nuclear Envelope During Early Development. Cell 166 (3), S. 664 - 678 (2016)
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Hoelz, A.; Glavy, J. S.; Beck, M.: Toward the atomic structure of the nuclear pore complex: when top down meets bottom up. Nature Structural and Molecular Biology 23 (7), S. 624 - 630 (2016)
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Ferber, M.; Kosinski, J.; Ori, A.; Rashid, U. J.; Moreno-Morcillo, M.; Simon, B.; Bouvier, G.; Batista, P. R.; Müller, C. W.; Beck, M. et al.; Nilges, M.: Automated structure modeling of large protein assemblies using crosslinks as distance restraints. Nature methods 13 (6), S. 515 - 520 (2016)
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von Appen, A.; Beck, M.: Structure Determination of the Nuclear Pore Complex With Three-Dimensional Cryo Electron Microscopy. Journal of Molecular Biology (London) 428 (10 Pt A), S. 2001 - 2010 (2016)
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Kosinski, J.; Mosalaganti, S.; von Appen, A.; Teimer, R.; DiGuilio, A. L.; Wan, W.; Bui, K. H.; Hagen, W. J. H.; Briggs, J. A. G.; Glavy, J. S. et al.; Hurt, E.; Beck, M.: Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science 352 (6283), S. 363 - 365 (2016)
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Ori, A.; Iskar, M.; Buczak, K.; Kastritis, P.; Parca, L.; Andrés-Pons, A.; Singer, S.; Bork, P.; Beck, M.: Spatiotemporal variation of mammalian protein complex stoichiometries. Genome Biology 17, 47 (2016)
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Silva-Martin, N.; Daudén, M. I.; Glatt, S.; Hoffmann, N. A.; Kastritis, P.; Bork, P.; Beck, M.; Müller, C. W.: The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex. PLoS One 11 (1), e0146457 (2016)
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Thierry, E.; Guilligay, D.; Kosinski, J.; Bock, T.; Gaudon, S.; Round, A.; Pflug, A.; Hengrung, N.; El Omari, K.; Baudin, F. et al.; Hart, D. J.; Beck, M.; Cusack, S.: Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains. Molecular Cell 61 (1), S. 125 - 137 (2016)
2015
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Poli, M.; Ori, A.; Child, T.; Jaroudi, S.; Spath, K.; Beck, M.; Wells, D.: Characterization and quantification of proteins secreted by single human embryos prior to implantation. Embo Molecular Medicine 7 (11), S. 1465 - 1479 (2015)
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von Appen, A.; Kosinski, J.; Sparks, L.; Ori, A.; DiGuilio, A. L.; Vollmer, B.; Mackmull, M.-T.; Banterle, N.; Parca, L.; Kastritis, P. et al.; Buczak, K.; Mosalaganti, S.; Hagen, W.; Andres-Pons, A.; Lemke, E. A.; Bork, P.; Antonin, W.; Glavy, J. S.; Bui, K. H.; Beck, M.: In situ structural analysis of the human nuclear pore complex. Nature 526 (7571), S. 140 - 143 (2015)
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Ori, A.; Toyama, B. H.; Harris, M. S.; Bock, T.; Iskar, M.; Bork, P.; Ingolia, N. T.; Hetzer, M. W.; Beck, M.: Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats. Cell Systems 1 (3), S. 224 - 237 (2015)
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Deniaud, A.; Karuppasamy, M.; Bock, T.; Masiulis, S.; Huard, K.; Garzoni, F.; Kerschgens, K.; Hentze, M. W.; Kulozik, A. E.; Beck, M. et al.; Neu-Yilik, G.; Schaffitzel, C.: A Network of SMG-8, SMG-9 and SMG-1 C-terminal Insertion Domain Regulates UPF1 Substrate Recruitment and Phosphorylation. Nucleic Acids Research (London) 43 (15), S. 7600 - 7611 (2015)
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Dodonova, S. O.; Diestelkoetter-Bachert, P.; von Appen, A.; Hagen, W. J. H.; Beck, R.; Beck, M.; Wieland, F.; Briggs, J. a. G.: VESICULAR TRANSPORT. A Structure of the COPI Coat and the Role of Coat Proteins in Membrane Vesicle Assembly. Science 349 (6244), S. 195 - 198 (2015)
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Male, G.; von Appen, A.; Glatt, S.; Taylor, N. M. I.; Cristovao, M.; Groetsch, H.; Beck, M.; Müller, C. W.: Architecture of TFIIIC and Its Role in RNA Polymerase III Pre-Initiation Complex Assembly. Nature Communications 6, 7387 (2015)
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Hurt, E.; Beck, M.: Towards understanding nuclear pore complex architecture and dynamics in the age of integrative structural analysis. Current Opinion in Cell Biology 34, S. 31 - 38 (2015)
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Mackmull, M.-T.; Iskar, M.; Parca, L.; Singer, S.; Bork, P.; Ori, A.; Beck, M.: Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). Molecular and Cellular Proteomics 14 (5), S. 1350 - 1360 (2015)
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Calviño, F. R.; Kharde, S.; Ori, A.; Hendricks, A.; Wild, K.; Kressler, D.; Bange, G.; Hurt, E.; Beck, M.; Sinning, I.: Symportin 1 Chaperones 5S RNP Assembly During Ribosome Biogenesis by Occupying an Essential rRNA-binding Site. Nature Communications 6, 6510 (2015)
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Kosinski, J.; von Appen, A.; Ori, A.; Karius, K.; Müller, C. W.; Beck, M.: Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures. Journal of Structural Biology 189 (3), S. 177 - 183 (2015)
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Gaik, M.; Flemming, D.; von Appen, A.; Kastritis, P.; Mücke, N.; Fischer, J.; Stelter, P.; Ori, A.; Bui, K. H.; Baßler, J. et al.; Barbar, E.; Beck, M.; Hurt, E.: Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. The Journal of Cell Biology: JCB 208 (3), S. 283 - 297 (2015)
2014
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Bock, T.; Chen, W.-H.; Ori, A.; Malik, N.; Silva-Martin, N.; Huerta-Cepas, J.; Powell, S. T.; Kastritis, P. L.; Smyshlyaev, G.; Vonkova, I. et al.; Kirkpatrick, J.; Doerks, T.; Nesme, L.; Baßler, J.; Kos, M.; Hurt, E.; Carlomagno, T.; Gavin, A.-C.; Barabas, O.; Müller, C. W.; van Noort, V.; Beck, M.; Bork, P.: An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum. Nucleic Acids Research (London) 42 (22), S. 13525 - 13533 (2014)
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Ostenfeld, M. S.; Jeppesen, D. K.; Laurberg, J. R.; Boysen, A. T.; Bramsen, J. B.; Primdal-Bengtson, B.; Hendrix, A.; Lamy, P.; Dagnaes-Hansen, F.; Rasmussen, M. H. et al.; Bui, K. H.; Fristrup, N.; Christensen, E. I.; Nordentoft, I.; Morth, J. P.; Jensen, J. B.; Pedersen, J. S.; Beck, M.; Theodorescu, D.; Borre, M.; Howard, K. A.; Dyrskjøt, L.; Ørntoft, T. F.: Cellular Disposal of miR23b by RAB27-dependent Exosome Release Is Linked to Acquisition of Metastatic Properties. Cancer research: an official organ of the American Association for Cancer Research 74 (20), S. 5758 - 5771 (2014)
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Winkler, J.; Ori, A.; Holzer, K.; Sticht, C.; Dauch, D.; Eiteneuer, E. M.; Pinna, F.; Geffers, R.; Ehemann, V.; Andres-Pons, A. et al.; Breuhahn, K.; Longerich, T.; Bermejo, J. L.; Gretz, N.; Zender, L.; Schirmacher, P.; Beck, M.; Singer, S.: Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer. Hepatology 60 (3), S. 884 - 895 (2014)
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Piazza, I.; Rutkowska, A.; Ori, A.; Walczak, M.; Metz, J.; Pelechano, V.; Beck, M.; Haering, C. H.: Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. Nature Structural and Molecular Biology 21 (6), S. 560 - 568 (2014)
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Beck, M.; Glavy, J. S.: Toward understanding the structure of the vertebrate nuclear pore complex. The Nucleus 5 (2), S. 119 - 123 (2014)
2013
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Bui, K. H.; von Appen, A.; DiGuilio, A. L.; Ori, A.; Sparks, L.; Mackmull, M.-T.; Bock, T.; Hagen, W.; Andrés-Pons, A.; Glavy, J. S. et al.; Beck, M.: Integrated structural analysis of the human nuclear pore complex scaffold. Cell 155 (6), S. 1233 - 1243 (2013)
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Thierbach, K.; von Appen, A.; Thoms, M.; Beck, M.; Flemming, D.; Hurt, E.: Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy. Structure 21 (9), S. 1672 - 1682 (2013)
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Banterle, N.; Bui, K. H.; Lemke, E. A.; Beck, M.: Fourier ring correlation as a resolution criterion for super-resolution microscopy. Journal of Structural Biology 183 (3), S. 363 - 367 (2013)
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Milles, S.; Huy Bui, K.; Koehler, C.; Eltsov, M.; Beck, M.; Lemke, E. A.: Facilitated aggregation of FG nucleoporins under molecular crowding conditions. EMBO Reports 14 (2), S. 178 - 183 (2013)
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Ori, A.; Banterle, N.; Iskar, M.; Andrés-Pons, A.; Escher, C.; Khanh Bui, H.; Sparks, L.; Solis-Mezarino, V.; Rinner, O.; Bork, P. et al.; Lemke, E. A.; Beck, M.: Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology 9, 648 (2013)
2012
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Herzog, F.; Kahraman, A.; Boehringer, D.; Mak, R.; Bracher, A.; Walzthoeni, T.; Leitner, A.; Beck, M.; Hartl, F.-U.; Ban, N. et al.; Malmström, L.; Aebersold, R.: Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry. Science 337 (6100), S. 1348 - 1352 (2012)
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Walzthoeni, T.; Claassen, M.; Leitner, A.; Herzog, F.; Bohn, S.; Förster, F.; Beck, M.; Aebersold, R.: False discovery rate estimation for cross-linked peptides identified by mass spectrometry. Nature Methods 9 (9), S. 901 - 903 (2012)
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Xu, M.; Beck, M.; Alber, F.: High-throughput subtomogram alignment and classification by Fourier space constrained fast volumetric matching. Journal of Structural Biology 178 (2), S. 152 - 164 (2012)
2011
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Beck, M.; Schmidt, A.; Malmstroem, J.; Claassen, M.; Ori, A.; Szymborska, A.; Herzog, F.; Rinner, O.; Ellenberg, J.; Aebersold, R.: The quantitative proteome of a human cell line. Molecular Systems Biology 7, 549 (2011)
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Schmidt, A.; Beck, M.; Malmström, J.; Lam, H.; Claassen, M.; Campbell, D.; Aebersold, R.: Absolute quantification of microbial proteomes at different states by directed mass spectrometry. Molecular Systems Biology 7, 510 (2011)
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Reiter, L.; Rinner, O.; Picotti, P.; Hüttenhain, R.; Beck, M.; Brusniak, M.-Y.; Hengartner, M. O.; Aebersold, R.: mProphet: automated data processing and statistical validation for large-scale SRM experiments. Nature Methods 8 (5), S. 430 - 435 (2011)
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Beck, M.; Topf, M.; Frazier, Z.; Tjong, H.; Xu, M.; Zhang, S.; Alber, F.: Exploring the spatial and temporal organization of a cell's proteome. Journal of Structural Biology 173 (3), S. 483 - 496 (2011)
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Beck, M.; Claassen, M.; Aebersold, R.: Comprehensive proteomics. Current Opinion in Biotechnology 22 (1), S. 3 - 8 (2011)
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Xu, M.; Beck, M.; Alber, F.: Template-free detection of macromolecular complexes in cryo electron tomograms. Bioinformatics 27 (13), S. i69 - i76 (2011)
2010
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Bohn, S.; Beck, F.; Sakata, E.; Walzthoeni, T.; Beck, M.; Aebersold, R.; Förster, F.; Baumeister, W.; Nickell, S.: Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proceedings of the National Academy of Sciences of the United States of America 107 (49), S. 20992 - 20997 (2010)
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Leitner, A.; Walzthoeni, T.; Kahraman, A.; Herzog, F.; Rinner, O.; Beck, M.; Aebersold, R.: Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics. Molecular and Cellular Proteomics 9 (8), S. 1634 - 1649 (2010)
2009
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Beck, M.; Malmström, J. A.; Lange, V.; Schmidt, A.; Deutsch, E. W.; Aebersold, R.: Visual proteomics of the human pathogen Leptospira interrogans. Nature Methods 6 (11), S. 817 - 823 (2009)
Zeitschriftenartikel
Medalia, N.; Beer, A.; Zwickl, P.; Mihalache, O.; Beck, M.; Medalia, O.; Navon, A.: Architecture and molecular mechanism of PAN, the archaeal proteasome regulatory ATPase. The Journal of Biological Chemistry 284 (34), S. 22952 - 22960 (2009)
Zeitschriftenartikel
Malmström, J.; Beck, M.; Schmidt, A.; Lange, V.; Deutsch, E. W.; Aebersold, R.: Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature 460 (11), S. 762 - 765 (2009)
2008
Zeitschriftenartikel
Rinner, O.; Seebacher, J.; Walzthoeni, T.; Mueller, L. N.; Beck, M.; Schmidt, A.; Mueller, M.; Aebersold, R.: Identification of cross-linked peptides from large sequence databases. Nature Methods 5 (4), S. 315 - 318 (2008)
Zeitschriftenartikel
Beck, M.; Medalia, O.: Structural and functional insights into nucleocytoplasmic transport. Histology and Histopathology 23 (8), S. 1025 - 1033 (2008)
2007
Zeitschriftenartikel
Beck, M.; Lucic, V.; Förster, F.; Baumeister, W.; Medalia, O.: Snapshots of nuclear pore complexes in action captured by cryo-electron tomography. Nature 449 (7162), S. 611 - 615 (2007)
Zeitschriftenartikel
Medalia, O.; Beck, M.; Ecke, M.; Weber, I.; Neujahr, R.; Baumeister, W.; Gerisch, G.: Organization of actin networks in intact filopodia. Current Biology 17, S. 79 - 84 (2007)
2006
Zeitschriftenartikel
Leis, A. P.; Beck, M.; Gruska, M.; Best, C.; Hegerl, R.; Baumeister, W.; Leis, J. W.: Cryo-electron tomography of biological specimens. IEEE Signal Processing Magazine 23 (3), S. 95 - 103 (2006)
2004
Zeitschriftenartikel
Beck, M.; Förster, F.; Ecke, M.; Plitzko, J. M.; Melchior, F.; Gerisch, G.; Baumeister, W.; Medalia, O.: Nuclear pore complex structure and dynamics revealed by cryoelectron tomography. Science 306 (5700), S. 1387 - 1390 (2004)

Buchkapitel (2)

2014
Buchkapitel
Ori, A.; Andrés-Pons, A.; Beck, M.: The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies. In: Methods in Cell Biology, Bd. 122, S. 117 - 146. Elsevier (2014)
2010
Buchkapitel
Förster, F.; Han, B.-G.; Beck, M.: Visual proteomics. In: Methods in Enzymology, Bd. 483, S. 215 - 243. Elsevier, Amsterdam (2010)
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