Max-Planck-Institut für Biophysik

Publikationen des Max-Planck-Institutes für Biophysik

Publikationen des Max-Planck-Institutes für Biophysik

Zeitschriftenartikel (3184)

2025

Zeitschriftenartikel

Stautz, J.; Griwatz, D.; Kaltwasser, S.; Mehdipour, A. R.; Ketter, S.; Thiel, C.; Wunnicke, D.; Schrecker, M.; Mills, D. J.; Hummer, G. et al.; Vonck, J.; Hänelt, I.: A short intrinsically disordered region at KtrB’s N-terminus facilitates allosteric regulation of K⁺ channel KtrAB. Nature Communications 16, 4252 (2025)

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Stuke, J. F. M.; Hummer, G.: AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy. Autophagy (2025)

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Kühlbrandt, W.; Carreira, L. A. M.; Yildiz, Ö.: Cryo-EM of Mitochondrial Complex I and ATP Synthase. Annual Review of Biophysics 54, S. 209 - 226 (2025)

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Bukhdruker, S.; Gushchin, I.; Shevchenko, V.; Kovalev, K.; Polovinkin, V.; Tsybrov, F.; Astashkin, R.; Alekseev, A.; Mikhaylov, A.; Bukhalovich, S. et al.; Bratanov, D.; Ryzhykau, Y.; Kuklina, D.; Caramello, N.; Rokitskaya, T.; Antonenko, Y.; Rulev, M.; Stoev, C.; Zabelskii, D.; Round, E.; Rogachev, A.; Borshchevskiy, V.; Ghai, R.; Bourenkov, G.; Zeghouf, M.; Cherfils, J.; Engelhard, M.; Chizhov, I.; Rodriguez-Valera, F.; Bamberg, E.; Gordeliy, V.: Proteorhodopsin insights into the molecular mechanism of vectorial proton transport. Science Advances 11 (16), eadu5303 (2025)

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Ros, U.; Martinez-Osorio, V.; Valiente, P. A.; Abdelwahab, Y.; Gojkovic, M.; Shalaby, R.; Zanna, S.; Saggau, J.; Wachsmuth, L.; Nemade, H. N. et al.; Zoeller, J.; Lottermoser, H.; Chen, Y.-G.; Ibrahim, M.; Kelepouras, K.; Vasilikos, L.; Bedoya, P.; Espiritu, R. A.; Müller, S.; Altmannova, V.; Tieleman, D. P.; Weir, J.; Langer, J. D.; Adam, M.; Walczak, H.; Wong, W. W.-L.; Liccardi, G.; Mollenhauer, M.; Pasparakis, M.; Peltzer, N.; García-Sáez, A. J.: MLKL activity requires a splicing-regulated, druggable intramolecular interaction. Molecular Cell 85 (2025)

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Zaghbani, S.; Faber, L.; Garcia Saez, A. J.: Convolutional Neural Network approach to classify mitochondrial morphologies. Computational Biology and Chemistry 118, 108477 (2025)

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Cook, A. S. I.; Chen, M.; Nguyen, T. N.; Cabezudo, A. C.; Khuu, G.; Rao, S.; Garcia, S. N.; Yang, M.; Iavarone, A. T.; Ren, X. et al.; Lazarou, M.; Hummer, G.; Hurley, J. H.: Structural pathway for PI3-kinase regulation by VPS15 in autophagy. Science 388 (6743), eadl3787 (2025)

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Taniguchi, R.; Orniacki, C.; Kreysing, J. P.; Zila, V.; Zimmerli, C. E.; Böhm, S.; Turoňová, B.; Kräusslich, H.-G.; Doye, V.; Beck, M.: Nuclear pores safeguard the integrity of the nuclear envelope. Nature Cell Biology (2025)

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Zabelskii, D.; Bukhdruker, S.; Bukhalovich, S.; Tsybrov, F.; Lamm, G. H. U.; Astashkin, R.; Doroginin, D.; Matveev, G.; Sudarev, V.; Kuzmin, A. et al.; Zinovev, E.; Vlasova, A.; Ryzhykau, Y.; Ilyinsky, N.; Gushchin, I.; Bourenkov, G.; Alekseev, A.; Round, A.; Wachtveitl, J.; Bamberg, E.; Gordeliy, V.: Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nature Structural & Molecular Biology (2025)

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Fuchs, J.; Fernández-Arévalo, U.; Demmer, U.; Díaz, E.; Ullmann, G. M.; Pierik, A. J.; Ermler, U.; Boll, M.: Enzymatic Birch reduction via hydrogen atom transfer at [4Fe-4S]-OH₂ and [8Fe-9S] clusters. Nature Communications 16, 3236 (2025)

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Amaro, R. E.; Åqvist, J.; Bahar, I.; Battistini, F.; Bellaiche, A.; Beltran, D.; Biggin, P. C.; Bonomi, M.; Bowman, G. R.; Bryce, R. A. et al.; Bussi, G.; Carloni, P.; Case, D. A.; Cavalli, A.; Chang, C.-E. A.; Cheatham, T. E.; Cheung, M. S.; Chipot, C.; Chong, L. T.; Choudhary, P.; Cisneros, G. A.; Clementi, C.; Collepardo-Guevara, R.; Coveney, P.; Covino, R.; Crawford, T. D.; Dal Peraro, M.; de Groot, B. L.; Delemotte, L.; De Vivo, M.; Essex, J. W.; Fraternali, F.; Gao, J.; Gelpí, J. L.; Gervasio, F. L.; González-Nilo, F. D.; Grubmüller, H.; Guenza, M. G.; Guzman, H. V.; Harris, S.; Head-Gordon, T.; Hernandez, R.; Hospital, A.; Huang, N.; Huang, X.; Hummer, G.; Hummer, G.; Iglesias-Fernández, J.; Jensen, J. H.; Jha, S.; Jiao, W.; Jorgensen, W. L.; Kamerlin, S. C. L.; Khalid, S.; Laughton, C.; Levitt, M.; Limongelli, V.; Lindahl, E.; Lindorff-Larsen, K.; Loverde, S.; Lundborg, M.; Luo, Y. L.; Luque, F. J.; Lynch, C. I.; MacKerell, A. D.; Magistrato, A.; Marrink, S. J.; Martin, H.; McCammon, J. A.; Merz, K.; Moliner, V.; Mulholland, A. J.; Murad, S.; Naganathan, A. N.; Nangia, S.; Noe, F.; Noy, A.; Oláh, J.; O'Mara, M. L.; Ondrechen, M. J.; Onuchic, J. N.; Onufriev, A.; Osuna, S.; Palermo, G.; Panchenko, A. R.; Pantano, S.; Parish, C.; Parrinello, M.; Perez, A.; Perez-Acle, T.; Perilla, J. R.; Pettitt, B. M.; Pietropaolo, A.; Piquemal, J.-P.; Poma, A. B.; Praprotnik, M.; Ramos, M. J.; Ren, P.; Reuter, N.; Roitberg, A.; Rosta, E.; Rovira, C.; Roux, B.; Rothlisberger, U.; Sanbonmatsu, K. Y.; Schlick, T.; Shaytan, A. K.; Simmerling, C.; Smith, J. C.; Sugita, Y.; Świderek, K.; Taiji, M.; Tao, P.; Tieleman, D. P.; Tikhonova, I. G.; Tirado-Rives, J.; Tuñón, I.; van der Kamp, M. W.; van der Spoel, D.; Velankar, S.; Voth, G. A.; Wade, R.; Warshel, A.; Welborn, V. V.; Wetmore, S. D.; Wheeler, T. J.; Wong, C. F.; Yang, L.-W.; Zacharias, M.; Orozco, M.: The need to implement FAIR principles in biomolecular simulations. Nature Methods (2025)

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Roeck, B. F.; Lotfipour Nasudivar, S.; Vorndran, M. R. H.; Schueller, L.; Yapici, F. I.; Rübsam, M.; von Karstedt, S.; Niessen, C. M.; Garcia-Saez, A. J.: Ferroptosis spreads to neighboring cells via plasma membrane contacts. Nature Communications 16, 2951 (2025)

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Eerlapally, R.; Hareendran, D. L.; Velasco, L.; Charisiadis, A.; Sauvan, M.; Debnath, J.; Moonshiram, D.; Draksharapu, A.: Impact of Lewis Acids on the Reactivity of a High-Valent Cu(III) Complex. Inorganic Chemistry (2025)

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Licheva, M.; Babic, R.; Pflaum, J.; Mancilla, H.; Wilfling, F.; Kraft, C.: To degrade or not to degrade: how phase separation modulates selective autophagy. Autophagy (2025)

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Zimmann, F.; McNicoll, F.; Thakur, P. K.; Blažíková, M.; Kubovčiak, J.; Hernández Cañás, M. C.; Nováková, Z.; Bařinka, C.; Kolář, M.; Staněk, D. et al.; Müller-McNicoll, M.; Cvačková, Z.: Retinitis pigmentosa-linked mutations impair the snRNA unwinding activity of SNRNP200 and reduce pre-mRNA binding of PRPF8. Cellular and Molecular Life Sciences 82, 103 (2025)

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Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Oorschot, V.; Brandstetter, M.; Yeroslaviz, A.; Briggs, J. A. G. et al.; Brennecke, J.; Beck, M.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell 188 (2025)

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Cortés Rodríguez, F. J.; Frattini, G.; Phloi-Montri, S.; Pinto Meireles, F. T.; Terrien, D. A.; Cruz-León, S.; Dal Peraro, M.; Schier, E.; Lindorff-Larsen, K.; Limpanuparb, T. et al.; Moreno, D. M.; Abriata, L. A.: MolecularWebXR: Multiuser discussions in chemistry and biology through immersive and inclusive augmented and virtual reality. Journal of Molecular Graphics and Modelling 135, 108932 (2025)

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Poveda Cuevas, S. A.; Lohachova, K.; Markusic, B.; Dikic, I.; Hummer, G.; Bhaskara, R.: Janus-like behavior of intrinsically disordered regions in reticulophagy. Autophagy 21 (3), S. 681 - 683 (2025)

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Zaghbani, S.; Pranti, R. K.; Faber, L.; Garcia-Saez, A. J.: MitoSkel: AI tool for semantic segmentation and quantification of mitochondria from light microscopy images. Biomedical Signal Processing and Control 106, 107762 (2025)

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Smarduch, S.; Moreno-Velasquez, S. D.; Ilic, D.; Dadsena, S.; Morant, R.; Ciprinidis, A.; Pereira, G.; Binder, M.; García-Sáez, A. J.; Acebrón, S. P.: A novel biosensor for the spatiotemporal analysis of STING activation during innate immune responses to dsDNA. The EMBO Journal (2025)

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Bailey, H. J.; Eisert, J.; Kazi, R.; Gerhartz, J.; Pieńkowska, D. E.; Dressel, I.; Vollrath, J.; Kondratov, I.; Matviyuk, T.; Tolmachova, N. et al.; Shah, V. J.; Giuliani, G.; Mosler, T.; Geiger, T. M.; Esteves, A. M.; Santos, S. P.; Sousa, R. L.; Bandeiras, T. M.; Leibrock, E.-M.; Bauer, U.; Leuthner, B.; Langer, J. D.; Wegener, A. A.; Nowak, R. P.; Sorrell, F. J.; Đikić, I.: An engineered cereblon optimized for high throughput screening and molecular glue discovery. Cell Chemical Biology 32 (2), S. 363 - 376.e10 (2025)

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Kreysing, J. P.; Heidari, M.; Zila, V.; Cruz-León, S.; Obarska-Kosinska, A.; Laketa, V.; Rohleder, L.; Welsch, S.; Köfinger, J.; Turoňová, B. et al.; Hummer, G.; Kräusslich, H.-G.; Beck, M.: Passage of the HIV capsid cracks the nuclear pore. Cell 188 (4), S. 930 - 943.e21 (2025)

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Kutzner, C.; Miletić, V.; Palacio Rodríguez, K.; Rampp, M.; Hummer, G.; de Groot, B. L.; Grubmüller, H.: Scaling of the GROMACS Molecular Dynamics Code to 65k CPU Cores on an HPC Cluster. Journal of Computational Chemistry 46 (5), e70059 (2025)

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Lee, Y.; Jin, C.; Ohgaki, R.; Xu, M.; Ogasawara, S.; Warshamanage, R.; Yamashita, K.; Murshudov, G.; Nureki, O.; Murata, T. et al.; Kanai, Y.: Structural basis of anticancer drug recognition and amino acid transport by LAT1. Nature Communications 16, 1635 (2025)

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Hoffmann, P. C.; Kim, H.; Obarska-Kosinska, A.; Kreysing, J. P.; Andino-Frydman, E.; Cruz-León, S.; Margiotta, E.; Cernikova, L.; Kosinski, J.; Turoňová, B. et al.; Hummer, G.; Beck, M.: Nuclear pore permeability and fluid flow are modulated by its dilation state. Molecular Cell 85 (3), S. 537 - 554.e11 (2025)

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Cutts, E. E.; Tetiker, D.; Kim, E.; Aragon, L.: Molecular mechanism of condensin I activation by KIF4A. The EMBO Journal 44 (3), S. 682 - 704 (2025)

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Licheva, M.; Pflaum, J.; Babic, R.; Mancilla, H.; Elsässer, J.; Boyle, E.; Hollenstein, D. M.; Jimenez-Niebla, J.; Pleyer, J.; Heinrich, M. et al.; Wieland, F.-G.; Brenneisen, J.; Eickhorst, C.; Brenner, J.; Jiang, S.; Hartl, M.; Welsch, S.; Hunte, C.; Timmer, J.; Wilfling, F.; Kraft, C.: Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy. Nature Cell Biology 27 (2), S. 283 - 297 (2025)

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Rutkauskas, M.; Kim, E.: In vitro dynamics of DNA loop extrusion by structural maintenance of chromosomes complexes. Current Opinion in Genetics & Development 90, 102284 (2025)

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Yin, M. D.; Lemaire, O. N.; Rosas Jiménez, J. G.; Belhamri, M.; Shevchenko, A.; Hummer, G.; Wagner, T.; Murphy, B. J.: Conformational dynamics of a multienzyme complex in anaerobic carbon fixation. Science 387 (6733), S. 498 - 504 (2025)

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Hayashi, K.; Hummer, G.; Joseph, J. A.; Li, R.; Nagai, T.; Onami, S.; Zhang, F.: A round table at IUPAB Congress in Kyoto 2024: Dreaming the next 50 years in our biophysics. Biophysics and Physicobiology 21 (Supplemental2), e212012 (2025)

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Pedrera, L.; Prieto Clemente, L.; Dahlhaus, A.; Lotfipour Nasudivar, S.; Tishina, S.; Olmo González, D.; Stroh, J.; Yapici, F. I.; Singh, R. P.; Grotehans, N. et al.; Langer, T.; García-Sáez, A. J.; von Karstedt, S.: Ferroptosis triggers mitochondrial fragmentation via Drp1 activation. Cell Death and Disease 16, 40 (2025)

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Introini, B.; Hahn, A.; Kühlbrandt, W.: Cryo-EM structure of the NDH-PSI-LHCI supercomplex from Spinacia oleracea. Nature Structural & Molecular Biology (2025)

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Xing, H.; Rosenkranz, R. R. E.; Rodriguez-Aliaga, P.; Lee, T.-T.; Majtner, T.; Böhm, S.; Turoňová, B.; Frydman, J.; Beck, M.: In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor. Nature 637 (8047), S. 983 - 990 (2025)

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Kraus, F.; He, Y.; Swarup, S.; Overmyer, K. A.; Jiang, Y.; Brenner, J.; Capitanio, C.; Bieber, A.; Jen, A.; Nightingale, N. M. et al.; Anderson, B. J.; Lee, C.; Paulo, J. A.; Smith, I. R.; Plitzko, J. M.; Gygi, S. P.; Schulman, B. A.; Wilfling, F.; Coon, J. J.; Harper, J. W.: Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST. Science Advances 11 (4), eadu5787 (2025)

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Münick, P.; Strubel, A.; Balourdas, D.-I.; Funk, J. S.; Mernberger, M.; Osterburg, C.; Dreier, B.; Schaefer, J. V.; Tuppi, M.; Yüksel, B. et al.; Schäfer, B.; Knapp, S.; Plückthun, A.; Stiewe, T.; Joerger, A. C.; Dötsch, V.: DARPin-induced reactivation of p53 in HPV-positive cells. Nature Structural & Molecular Biology (2025)

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Catapano, C.; Dietz, M. S.; Kompa, J.; Jang, S.; Freund, P.; Johnsson, K.; Heilemann, M.: Long-term single-molecule tracking in living cells using weak-affinity protein labeling. Angewandte Chemie, International Edition in English 64 (1), e202413117 (2025)

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Oo, J. A.; Warwick, T.; Pálfi, K.; Lam, F.; McNicoll, F.; Prieto-Garcia, C.; Günther, S.; Cao, C.; Zhou, Y.; Gavrilov, A. A. et al.; Razin, S. V.; Cabrera-Orefice, A.; Wittig, I.; Pullamsetti, S. S.; Kurian, L.; Gilsbach, R.; Schulz, M. H.; Dikic, I.; Müller-McNicoll, M.; Brandes, R. P.; Leisegang, M. S.: Long non-coding RNAs direct the SWI/SNF complex to cell type-specific enhancers. Nature Communications 16, 131 (2025)

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Pradhan, B.; Deep, A.; König, J.; Baaske, M. D.; Corbett, K. D.; Kim, E.: Loop-extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex. Molecular Cell 85 (2025)

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Etxebeste-Mitxeltorena, M.; Flores-Romero, H.; Ramos-Inza, S.; Masiá, E.; Nenchova, M.; Montesinos, J.; Martinez-Gonzalez, L.; Porras, G.; Orzáez, M.; Vicent, M. J. et al.; Gil, C.; Area-Gomez, E.; Garcia-Saez, A. J.; Martinez, A.: Modulation of Mitochondria-Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis Model. Journal of Medicinal Chemistry 68 (2), S. 1179 - 1194 (2025)

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Karimi, K.; Zöller, J.; Hofmann, T.; Zangl, R.; Schulte, J.; Langer, J. D.; Schmidt, C.; Morgner, N.: MS SIEVE – Pushing the Limits for Biomolecular Mass Spectrometry. Journal of the American Society for Mass Spectrometry 36 (1), S. 91 - 99 (2025)

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Mandal, T.; Brandt, N.; Tempra, C.; Javanainen, M.; Fábián, B.; Chiantia, S.: A comparison of lipid diffusive dynamics in monolayers and bilayers in the context of interleaflet coupling. Biochimica et Biophysica Acta: BBA 1867, 184388 (2025)

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Periasamy, A.; Ornelas, P.; Bausewein, T.; Mitchell, N.; Zhao, J.; Quinn, L. M.; Kuehlbrandt, W.; Gulbis, J. M.: Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM. IUCrJ 12 (1) (2025)

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2024

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Sennett, C.; Jia, W.; Khalil, J. S.; Hindle, M. S.; Coupland, C.; Calaminus, S. D. J.; Langer, J. D.; Frost, S.; Naseem, K. M.; Rivero, F. et al.; Ninkina, N.; Buchman, V.; Aburima, A.: α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly. Cells 13 (24), 2089 (2024)

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Herhaus, L.; Gestal-Mato, U.; Eapen, V. V.; Mačinković, I.; Bailey, H. J.; Prieto-Garcia, C.; Misra, M.; Jacomin, A.-C.; Ammanath, A. V.; Bagarić, I. et al.; Michaelis, J.; Vollrath, J.; Bhaskara, R. M.; Bündgen, G.; Covarrubias-Pinto, A.; Husnjak, K.; Zöller, J.; Gikandi, A.; Ribičić, S.; Bopp, T.; van der Heden van Noort, G. J.; Langer, J. D.; Weigert, A.; Harper, J. W.; Mancias, J. D.; Đikić, I.: IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion. Cell 187 (7), S. 7285 - 7302 (2024)

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Rosas Jiménez, J. G.; Fábián, B.; Hummer, G.: Faster Sampling in Molecular Dynamics Simulations with TIP3P-F Water. Journal of Chemical Theory and Computation 20 (24), S. 11068 - 11081 (2024)

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Sogues, A.; Leigh, K. E.; Halingstad, E. V.; Van der Verren, S. E.; Cecil, A. J.; Fioravanti, A.; Pak, A. J.; Kudryashev, M.; Remaut, H.: Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology. Proceedings of the National Academy of Sciences of the United States of America 121 (51), e2415351121 (2024)

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Steinhilper, R.; Boß, L.; Freibert, S.-A.; Schulz, V.; Krapoth, N.; Kaltwasser, S.; Lill, R.; Murphy, B. J.: Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex. Nature Communications 15, 10559 (2024)

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Sieber, A.; Parr, M.; Ehr, J. v.; Dhamotharan, K.; Kielkowski, P.; Brewer, T.; Schäpers, A.; Krafczyk, R.; Qi, F.; Schlundt, A. et al.; Frishman, D.; Lassak, J.: EF-P and its paralog EfpL (YeiP) differentially control translation of proline-containing sequences. Nature Communications 15, 10465 (2024)

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Pfeil-Gardiner, O.; Rosa, H. V. D.; Riedel, D.; Chen, Y. S.; Lörks, D.; Kükelhan, P.; Linck, M.; Müller, H.; Van Petegem, F.; Murphy, B. J.: Elemental mapping in single-particle reconstructions by reconstructed electron energy-loss analysis. Nature Methods 21, S. 2299 - 2306 (2024)

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Heidari, M.; Sikora, M.; Hummer, G.: Refined Protein-Sugar Interactions in the Martini Force Field. Journal of Chemical Theory and Computation 20 (22), S. 10259 - 10265 (2024)

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Lotfipour Nasudivar, S.; Pedrera, L.; García-Sáez, A. J.: Iron-Induced Lipid Oxidation Alters Membrane Mechanics Favoring Permeabilization. Langmuir 40 (47), S. 2561 - 2568 (2024)

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Dubach, V. R. A.; San Segundo-Acosta, P.; Murphy, B. J.: Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase. Nature Structural & Molecular Biology 31 (11), S. 1769 - 1777 (2024)

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Prieto-Garcia, C.; Matkovic, V.; Mosler, T.; Li, C.; Liang, J.; Oo, J. A.; Haidle, F.; Mačinković, I.; Cabrera-Orefice, A.; Berkane, R. et al.; Giuliani, G.; Xu, F.; Jacomin, A.-C.; Tomaskovic, I.; Basoglu, M.; Hoffmann, M. E.; Rathore, R.; Cetin, R.; Boutguetait, D.; Bozkurt, S.; Hernández Cañás, M. C.; Keller, M.; Busam, J.; Shah, V. J.; Wittig, I.; Kaulich, M.; Beli, P.; Galej, W. P.; Ebersberger, I.; Wang, L.; Münch, C.; Stolz, A.; Brandes, R. P.; Tse, W. K. F.; Eimer, S.; Stainier, D. Y. R.; Legewie, S.; Zarnack, K.; Müller-McNicoll, M.; Dikic, I.: Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. Science 386 (6723), S. 768 - 776 (2024)

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Laub, V.; Nan, E.; Elias, L.; Donaldson, I. J.; Bentsen, M.; Rusling, L. A.; Schupp, J.; Lun, J. H.; Plate, K. H.; Looso, M. et al.; Langer, J. D.; Günther, S.; Bobola, N.; Schulte, D.: Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4. Nucleic Acids Research 52 (20), gkae864, S. 12262 - 12280 (2024)

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Rahm, J. V.; Balakrishnan, A.; Wehrheim, M.; Kaminer, A.; Glogger, M.; Kessler, L. F.; Kaschube, M.; Barth, H.-D.; Heilemann, M.: Fast and Long-Term Super-Resolution Imaging of Endoplasmic Reticulum Nano-structural Dynamics in Living Cells Using a Neural Network. Small science 5 (1), 2400385 (2024)

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Li, Y.; Arghittu, S. M.; Dietz, M. S.; Hella, G. J.; Haße, D.; Ferraris, D. M.; Freund, P.; Barth, H.-D.; Iamele, L.; de Jonge, H. et al.; Niemann, H. H.; Covino, R.; Heilemann, M.: Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells. Nature Communications 15, 9486 (2024)

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Sushkin, M. E.; Jung, M.; Lemke, E. A.: Tuning the Functionality of Designer Translating Organelles with Orthogonal tRNA Synthetase/tRNA Pairs. Journal of Molecular Biology 436 (21), 168728 (2024)

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Rosenkranz, R. R. E.; Vraggalas, S.; Keller, M.; Sankaranarayanan, S.; McNicoll, F.; Löchli, K.; Bublak, D.; Benhamed, M.; Crespi, M.; Berberich, T. et al.; Bazakos, C.; Feldbrügge, M.; Schleiff, E.; Müller-McNicoll, M.; Zarnack, K.; Fragkostefanakis, S.: A plant-specific clade of serine/arginine-rich proteins regulates RNA splicing homeostasis and thermotolerance in tomato. Nucleic Acids Research 52 (19), gkae730, S. 11466 - 11480 (2024)

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Poveda-Cuevas, S. A.; Lohachova, K.; Markusic, B.; Dikic, I.; Hummer, G.; Bhaskara, R. M.: Intrinsically disordered region amplifies membrane remodeling to augment selective ER-phagy. Proceedings of the National Academy of Sciences of the United States of America 121 (44), e2408071121 (2024)

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Schartel, L.; Jann, C.; Wierczeiko, A.; Butto, T.; Mündnich, S.; Marchand, V.; Motorin, Y.; Helm, M.; Gerber, S.; Lemke, E. A.: Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles. Nature Communications 15, 9177 (2024)

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Wilm, M.: Nanoelectrospray based synthesis of large, transportable membranes with integrated membrane proteins. Scientific Reports 14, 25192 (2024)

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Joshi, T.; Demmer, U.; Schneider, C.; Glaser, T.; Warkentin, E.; Ermler, U.; Mack, M.: The phosphatase RosC from Streptomyces davaonensis is used for roseoflavin biosynthesis and has evolved to largely prevent dephosphorylation of the important cofactor riboflavin-5'-phosphate. Journal of Molecular Biology 436 (20), 168734 (2024)

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Grizel, A. V.; Gorsheneva, N. A.; Stevenson, J. B.; Pflaum, J.; Wilfling, F.; Rubel, A. A.; Chernoff, Y. O.: Osmotic stress induces formation of both liquid condensates and amyloids by a yeast prion domain. Journal of Biological Chemistry 300 (10), 107766 (2024)

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Introini, B.; Cui, W.; Chu, X.; Zhang, Y.; Alves, A. C.; Eckhardt-Strelau, L.; Golusik, S.; Tol, M.; Vogel, H.; Yuan, S. et al.; Kudryashev, M.: Structure of tetrameric forms of the serotonin-gated 5-HT3A receptor ion channel. The EMBO Journal 43 (20), S. 4451 - 4471 (2024)

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Mukherjee, R.; Bhattacharya, A.; Mello-Vieira, J.; Kuncha, S. K.; Hoffmann, M.; Gonzalez, A.; Rathore, R.; Chadha, A.; Shin, D.; Colby, T. et al.; Matic, I.; Mukherjee, S.; Misra, M.; Dikic, I.: Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis. Autophagy (2024)

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Xavier, A.; Đikić, I.: Feeding cancer to death - a triad of aromatic acids reduces tumor growth. Cell Death & Differentiation 31, S. 1239 - 1241 (2024)

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Kew, C.; Prieto-Garcia, C.; Bhattacharya, A.; Tietgen, M.; MacNair, C. R.; Carfrae, L. A.; Mello-Vieira, J.; Klatt, S.; Cheng, Y.-L.; Rathore, R. et al.; Gradhand, E.; Fleming, I.; Tan, M.-W.; Göttig, S.; Kempf, V. A. J.; Đikić, I.: The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii. Nature Communications 15, 7939 (2024)

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Dietrich, L.; Agip, A.-N. A.; Kunz, C.; Schwarz, A.; Kühlbrandt, W.: In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells. Science 385 (6713), S. 1086 - 1090 (2024)

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Berndt, C.; Alborzinia, H.; Amen, V. S.; Ayton, S.; Barayeu, U.; Bartelt, A.; Bayir, H.; Bebber, C. M.; Birsoy, K.; Böttcher, J. P. et al.; Brabletz, S.; Brabletz, T.; Brown, A. R.; Brüne, B.; Bulli, G.; Bruneau, A.; Chen, Q.; DeNicola, G. M.; Dick, T. P.; Distéfano, A.; Dixon, S. J.; Engler, J. B.; Esser-von Bieren, J.; Fedorova, M.; Friedmann Angeli, J. P.; Friese, M. A.; Fuhrmann, D. C.; García-Sáez, A. J.; Garbowicz, K.; Götz, M.; Gu, W.; Hammerich, L.; Hassannia, B.; Jiang, X.; Jeridi, A.; Kang, Y. P.; Kagan, V. E.; Konrad, D. B.; Kotschi, S.; Lei, P.; Le Tertre, M.; Lev, S.; Liang, D.; Linkermann, A.; Lohr, C.; Lorenz, S.; Luedde, T.; Methner, A.; Michalke, B.; Milton, A. V.; Min, J.; Mishima, E.; Müller, S.; Motohashi, H.; Muckenthaler, M. U.; Murakami, S.; Olzmann, J. A.; Pagnussat, G.; Pan, Z.; Papagiannakopoulos, T.; Pedrera Puentes, L.; Pratt, D. A.; Proneth, B.; Ramsauer, L.; Rodriguez, R.; Saito, Y.; Schmidt, F.; Schmitt, C.; Schulze, A.; Schwab, A.; Schwantes, A.; Soula, M.; Spitzlberger, B.; Stockwell, B. R.; Thewes, L.; Thorn-Seshold, O.; Toyokuni, S.; Tonnus, W.; Trumpp, A.; Vandenabeele, P.; Vanden Berghe, T.; Venkataramani, V.; Vogel, F. C. E.; von Karstedt, S.; Wang, F.; Westermann, F.; Wientjens, C.; Wilhelm, C.; Wölk, M.; Wu, K.; Yang, X.; Yu, F.; Zou, Y.; Conrad, M.: Ferroptosis in health and disease. Redox Biology: an official journal of the Society for Free Radical Biology and Medicine 75, 103211 (2024)

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Vallat, B.; Webb, B. M.; Westbrook, J. D.; Goddard, T. D.; Hanke, C. A.; Graziadei, A.; Peisach, E.; Zalevsky, A.; Sagendorf, J.; Tangmunarunkit, H. et al.; Voinea, S.; Sekharan, M.; Yu, J.; A M J J Bonvin, A.; DiMaio, F.; Hummer, G.; Meiler, J.; Tajkhorshid, E.; Ferrin, T. E.; Lawson, C. L.; Leitner, A.; Rappsilber, J.; Seidel, C. A. M.; Jeffries, C. M.; Burley, S. K.; Hoch, J. C.; Kurisu, G.; Morris, K.; Patwardhan, A.; Velankar, S.; Schwede, T.; Trewhella, J.; Kesselman, C.; Berman, H. M.; Sali, A.: IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods. Journal of Molecular Biology 436 (17), 168546 (2024)

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Kuhn, B. T.; Zöller, J.; Zimmermann, I.; Gemeinhardt, T.; Özkul, D. H.; Langer, J. D.; Seeger, M. A.; Geertsma, E. R.: Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA. Nature Communications 15, 7518 (2024)

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Lizarrondo, J.; Wilfling, F.: Selective autophagy of macromolecular complexes: what does it take to be taken? Journal of Molecular Biology 436, 168574 (2024)

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Wilfling, F.; Graef, M.: Molecular Mechanisms and Physiological Functions of Autophagy. Journal of Molecular Biology 436, 168692 (2024)

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Nüesch, M. F.; Pietrek, L.; Holmstrom, E. D.; Nettels, D.; von Roten, V.; Kronenberg-Tenga, R.; Medalia, O.; Hummer, G.; Schuler, B.: Nanosecond chain dynamics of single-stranded nucleic acids. Nature Communications 15 (1), 6010 (2024)

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Schneider, S.; Kühlbrandt, W.; Yildiz, Ö.: Complementary structures of the yeast phosphate transporter Pho90 provide insights into its transport mechanism. Structure 32 (7), S. 979 - 988.e4 (2024)

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Ehr, J. v.; Oberstrass, L.; Yazgan, E.; Schnaubelt, L. I.; Blümel, N.; McNicoll, F.; Weigand, J. E.; Zarnack, K.; Müller-McNicoll, M.; Korn, S. M. et al.; Schlundt, A.: Arid5a uses disordered extensions of its core ARID domain for distinct DNA- and RNA-recognition and gene regulation. Journal of Biological Chemistry 300 (7), 107457 (2024)

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Liu, J.; Corroyer-Dulmont, S.; Pražák, V.; Khusainov, I.; Bahrami, K.; Welsch, S.; Vasishtan, D.; Obarska-Kosińska, A.; Thorkelsson, S. R.; Grünewald, K. et al.; Quemin, E. R. J.; Turoňová, B.; Locker, J. K.: The palisade layer of the poxvirus core is composed of flexible A10 trimers. Nature Structural & Molecular Biology 31, S. 1105 - 1113 (2024)

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Eerlapally, R.; Vechalapu, S. K.; Duraisamy, S.; Hareendran, D. L.; Debnath, J.; Allimuthu, D.; Draksharapu, A.: A Cu(ii) pseudopeptide complex: a surrogate to a formal Cu(iii) species in water and an inhibitor of cancer cell proliferation. Inorganic Chemistry Frontiers 11, S. 5172 - 5184 (2024)

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Ri, K.; Weng, T.-H.; Claveras Cabezudo, A.; Jösting, W.; Zhang, Y.; Bazzone, A.; Leong, N. C. P.; Welsch, S.; Doty, R. T.; Gursu, G. et al.; Lim, T. J. Y.; Schmidt, S. L.; Abkowitz, J. L.; Hummer, G.; Wu, D.; Nguyen, L. N.; Safarian, S.: Molecular mechanism of choline and ethanolamine transport in humans. Nature 630, S. 501 - 508 (2024)

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Khusainov, I.; Romanov, N.; Goemans, C.; Turoňová, B.; Zimmerli, C. E.; Welsch, S.; Langer, J. D.; Typas, A.; Beck, M.: Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction. Nature Communications 15, 4783 (2024)

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Dadsena, S.; Cuevas Arenas, R.; Vieira, G.; Brodesser, S.; Melo, M. N.; García-Sáez, A. J.: Lipid unsaturation promotes BAX and BAK pore activity during apoptosis. Nature Communications 15, 4700 (2024)

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Gauger, M.; Heinz, M.; Halbritter, A.-L. J.; Stelzl, L. S.; Erlenbach, N.; Hummer, G.; Sigurdsson, S. T.; Prisner, T.: Structure and internal dynamics of short RNA duplexes determined by a combination of pulsed EPR methods and MD simulations. Angewandte Chemie, International Edition in English 63, e202402498 (2024)

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Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Mutational and structural studies of (βα)₈-barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism. Protein Science 33 (6), e5018 (2024)

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Froehlich, T.; Jenner, A.; Cavarischia-Rega, C.; Fagbadebo, F. O.; Lurz, Y.; Frecot, D. I.; Kaiser, P. D.; Nueske, S.; Scholz, A. M.; Schäffer, E. et al.; Garcia Saez, A. J.; Macek, B.; Rothbauer, U.: Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1. Life science alliance 7 (8), e202402608 (2024)

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Fábián, B.; Javanainen, M.: Energetics of the Transmembrane Peptide Sorting by Hydrophobic Mismatch. The Journal of Physical Chemistry Letters 15 (20), S. 5344 - 5349 (2024)

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Zhao, D. Y.; Bäuerlein, F. J. B.; Saha, I.; Hartl, F. U.; Baumeister, W.; Wilfling, F.: Autophagy preferentially degrades non-fibrillar polyQ aggregates. Molecular Cell 84 (10), S. 1980 - 1994.e8 (2024)

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Wang, J.; Heinz, M.; Han, K.; Shah, V. J.; Hasselbeck, S.; Schwalm, M. P.; Rathore, R.; Hummer, G.; Zhou, J.; Dikic, I. et al.; Cheng, X.: Thalidomide derivatives degrade BCL-2 by reprogramming the binding surface of CRBN. Cell Reports Physical Science 5 (5), 101960 (2024)

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Cruz-León, S.; Majtner, T.; Hoffmann, P. C.; Kreysing, J. P.; Kehl, S.; Tuijtel, M.; Schaefer, S. L.; Geißler, K.; Beck, M.; Turoňová, B. et al.; Hummer, G.: High-confidence 3D template matching for cryo-electron tomography. Nature Communications 15, 3992 (2024)

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Tuijtel, M.; Cruz-León, S.; Kreysing, J. P.; Welsch, S.; Hummer, G.; Beck, M.; Turoňová, B.: Thinner is not always better: Optimizing cryo-lamellae for subtomogram averaging. Science Advances 10 (17), eadk6285 (2024)

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Adolph, C.; Cheung, C.-Y.; McNeil, M. B.; Jowsey, W. J.; Williams, Z. C.; Hards, K.; Harold, L. K.; Aboelela, A.; Bujaroski, R. S.; Buckley, B. J. et al.; Tyndall, J. D. A.; Li, Z.; Langer, J. D.; Preiss, L.; Meier, T.; Steyn, A. J. C.; Rhee, K. Y.; Berney, M.; Kelso, M. J.; Cook, G. M.: A dual-targeting succinate dehydrogenase and F₁F_o-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. Cell Chemical Biology 31, S. 683 - 698.e7 (2024)

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Lyratzakis, A.; Daskalakis, V.; Xie, H.; Tsiotis, G.: The synergy between the PscC subunits for electron transfer to the P₈₄₀ special pair in Chlorobaculum tepidum. Photosynthesis Research 160 (2-3), S. 87 - 96 (2024)

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Schulz, V.; Steinhilper, R.; Oltmanns, J.; Freibert, S.-A.; Krapoth, N.; Linne, U.; Welsch, S.; Hoock, M. H.; Schünemann, V.; Murphy, B. J. et al.; Lill, R.: Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nature Communications 15, 3269 (2024)

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Aziz, I.; Kayastha, K.; Kaltwasser, S.; Vonck, J.; Welsch, S.; Murphy, B. J.; Kahnt, J.; Wu, D.; Wagner, T.; Shima, S. et al.; Ermler, U.: Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis. PNAS 121 (14), e2315568121 (2024)

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Bullerjahn, J. T.; Hanson, S. M.: Extracting thermodynamic properties from van ’t Hoff plots with emphasis on temperature-sensing ion channels. Temperature 11 (1), S. 60 - 71 (2024)

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Johnson, A. G.; Mayer, M. L.; Schaefer, S. L.; McNamara-Bordewick, N. K.; Hummer, G.; Kranzusch, P. J.: Structure and assembly of a bacterial gasdermin pore. Nature 628 (8008), S. 657 - 663 (2024)

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Köfinger, J.; Hummer, G.: Encoding prior knowledge in ensemble refinement. The Journal of Chemical Physics 160, 114111 (2024)

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Lasham, J.; Djurabekova, A.; Zickermann, V.; Vonck, J.; Sharma, V.: Role of Protonation States in the Stability of Molecular Dynamics Simulations of High-Resolution Membrane Protein Structures. The Journal of Physical Chemistry B 128 (10), S. 2304 - 2316 (2024)

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Pietrek, L. M.; Stelzl, L. S.; Hummer, G.: Hierarchical Assembly of Single-Stranded RNA. Journal of Chemical Theory and Computation 20 (5), S. 2246 - 2260 (2024)

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Blanc, F. E. C.; Hummer, G.: Mechanism of proton-powered c-ring rotation in a mitochondrial ATP synthase. PNAS 121 (11), e2314199121 (2024)

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