
Publikationen des Max-Planck-Institutes für Biophysik
Zeitschriftenartikel (3247)
2026
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Ubiquitination and autophagy in host-pathogen interactions: from immune surveillance to therapeutic targeting. Nature Reviews Immunology (2026)
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Autophagy regulation by phase separation, avidity, and wetting. Trends in Biochemical Sciences 51 (1), S. 27 - 38 (2026)
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Systematic membrane thickness variation across cellular organelles revealed by cryo-ET. Journal of Cell Biology 225 (1), e202504053 (2026)
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Integrative Multiscale Simulations Uncover the Mechanistic Principles Governing COPII Mediated Vesicle Formation. The Journal of Membrane Biology 259 (1), 1 (2026)
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AI-guided transition path sampling of lipid flip-flop and membrane nanoporation. Nature Communications 17, 224 (2026)
2025
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Metabolic silencing induced by the small bacterial membrane protein YohP. iScience 28 (12), 114123 (2025)
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Exploring shaped focused ion beams for lamella preparation. Ultramicroscopy 282, 114302 (2025)
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Structural Role of Conformational Heterogeneity and Juxtamembrane Regions in the Ephrin A1 Interactions With the EphA2 Receptor Ligand-binding Domain. Journal of Molecular Biology 437 (24), 169454 (2025)
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Fast, Bright, and Reversible Fluorescent Labeling of Rhodamine-Binding Proteins. Journal of the American Chemical Society (angenommen)
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Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities. Embo Molecular Medicine (2025)
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Dynamic regulation of cell death signaling. Current Opinion in Cell Biology 97, 102583 (2025)
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Automated removal of corrupted tilts in cryo-electron tomography. Journal of Structural Biology: X 12, 100130 (2025)
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A new rapid-degradation system combined with super-resolution microscopy. Nature Reviews Molecular Cell Biology 26 (12), S. 904 (2025)
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Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation. Angewandte Chemie (International Ed. in English), S. e16809 (2025)
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Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body. Nature Communications 16, 10689 (2025)
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Getting sticky: How nuclear speckles tune the condensation-prone proteome. Molecular Cell 85 (22), S. 4116 - 4118 (2025)
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The Arabidopsis thaliana nuclear pore complex structure reveals conserved and distinct features. Nature Plants 11, S. 2198 - 2199 (2025)
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In situ structure of a gap junction-stomatin complex. Science Advances 11 (45), eaea8596 (2025)
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Multivalent Interactions Between the Picornavirus 3C(D) Main Protease and RNA Oligonucleotides Induce Liquid-Liquid Phase Separation. Viruses 17 (11), 1473 (2025)
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Mitochondrial dynamics and pore formation in regulated cell death pathways. Trends in Biochemical Sciences 50 (11), S. 1001 - 1014 (2025)
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In situ architecture of the nuclear pore complex of the higher plant Arabidopsis thaliana. Nature Plants 11, S. 2368 - 2380 (2025)
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SND3 is the membrane insertase within a distinct SEC61 translocon complex. Nature Communications 16, 9566 (2025)
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Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. Nature Catalysis 8 (10), S. 1086 - 1099 (2025)
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Dissecting the RAD51–BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics. Journal of Chemical Information and Modeling 65 (21), S. 11965 - 11978 (2025)
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A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles. Cell 188 (21), S. 5995 - 6011 (2025)
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The small GTPase Ran defines nuclear pore complex asymmetry. Cell 188 (21), S. 5931 - 5946 (2025)
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A Multi-level Perspective on the Evolution of Orthologs and Their Functions. Journal of Molecular Evolution 93, S. 720 - 729 (2025)
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Shaping the Glycan Landscape: Hidden Relationships between Linkage and Ring Distortions Induced by Carbohydrate-Active Enzymes. Journal of the American Chemical Society 147 (42), S. 38376 - 38389 (2025)
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cryoTIGER: deep-learning based tilt interpolation generator for enhanced reconstruction in cryo electron tomography. Communications Biology 8, 1443 (2025)
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The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion. Proceedings of the National Academy of Sciences of the United States of America 122 (41), e2426476122 (2025)
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A Chemically Induced CRISPR/dCas13FCPF Platform for Precise and Programmable RNA Regulation. Journal of Medicinal Chemistry 68, S. 22633 - 22649 (2025)
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How does Mycoplasma pneumoniae scavenge lipids from its host membranes? Science Advances 11 (40), eady4746 (2025)
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Convolutional Neural Network approach to classify mitochondrial morphologies. Computational Biology and Chemistry 118, 108477 (2025)
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition. Cell Reports 44 (9), 116188 (2025)
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AlphaFold modeling of polyubiquitin complexes and covalently linked proteins. Cell Reports Physical Science 6 (9), 102796 (2025)
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Kinetic mechanisms of electron bifurcation with electron transfer flavoprotein, NADH, butyryl-CoA dehydrogenase, and ferredoxin reveal a semiquinone cycle. Journal of Biological Chemistry 301 (10), 110727 (2025)
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Activator of apoptosis harakiri (HRK) localisation at mitochondria alters mitochondrial morphology independently of other BCL-2 proteins. The FEBS Journal (2025)
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p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners. eLife 13, RP103537 (2025)
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Martini 3 Coarse-Grained Models for Carbon Nanomaterials. Journal of Chemical Theory and Computation 21 (18), S. 9035 - 9053 (2025)
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Bacterial cell widening alters periplasmic size and activates envelope stress responses. The EMBO Journal 44 (20), S. 5816 - 5833 (2025)
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Subtomogram averages of mitochondrial ATP synthase dimers from plants show a conserved extra density at the peripheral stalk. IUCrJ 12, S. 563 - 569 (2025)
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P-type ATPase magnesium transporter MgtA acts as a dimer. Nature Structural & Molecular Biology 32 (9), S. 1633 - 1643 (2025)
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STIM1 transmembrane helix dimerization captured by AI-guided transition path sampling. Proceedings of the National Academy of Sciences of the United States of America 122 (35), e2506516122 (2025)
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An integrated transcriptomic and proteomic map of the mouse hippocampus at synaptic resolution. Nature Communications 16, 7942 (2025)
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Opportunities in proximity modulation: Bridging academia and industry. Molecular Cell 85 (16), S. 3012 - 3022 (2025)
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Detection and Quantitation of Small Proteins Using Mass Spectrometry. Molecular & Cellular Proteomics 24 (9), 101052 (2025)
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Electron flow in hydrogenotrophic methanogens under nickel limitation. Nature 644 (8076), S. 490 - 496 (2025)
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The rapidly expanding role of LC3-interacting regions in autophagy. Journal of Cell Biology 224 (8), e202504076 (2025)
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Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery. Nature Cell Biology 27 (8), S. 1272 - 1287 (2025)
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Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection. The EMBO Journal 44 (15), S. 4252 - 4279 (2025)
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Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nature Structural & Molecular Biology 32 (8), S. 1347 - 1357 (2025)
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MitoSkel: AI tool for semantic segmentation and quantification of mitochondria from light microscopy images. Biomedical Signal Processing and Control 106, 107762 (2025)
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The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior. ACS Central Science 11 (9), S. 1598 - 1610 (2025)
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In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment. Proceedings of the National Academy of Sciences of the United States of America 122 (31), e2511890122 (2025)
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Structures of Chaetomium thermophilum TOM complexes with bound preproteins. Proceedings of the National Academy of Sciences of the United States of America 122 (29), e2507279122 (2025)
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Rapid depletion and super-resolution microscopy reveal dual roles of SRSF5 in coordinating nuclear speckle-paraspeckle crosstalk during cellular stress. Nucleic Acids Research 53, gkaf713 (2025)
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A constricted mitochondrial morphology formed during respiration. Nature Communications 16, 5314 (2025)
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The RNF/NQR redox pumps: a versatile system for energy transduction in bacteria and archaea. Applied Microbiology and Biotechnology 109, 148 (2025)
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Membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper. Communications Biology 8, 936 (2025)
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The Multifaceted Role of Calcium Signaling in Regulated Necrosis. Biomolecules 15 (6), 854 (2025)
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Cryo-EM structure of the NDH-PSI-LHCI supercomplex from Spinacia oleracea. Nature Structural & Molecular Biology 32 (6), S. 968 - 978 (2025)
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Dipolar Cross-Correlations in Aqueous Systems: How Surfaces Influence Water's Action at a Distance. Journal of Chemical Theory and Computation 21, S. 5686 - 5696 (2025)
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Special Issue – Cell Biology of Mitochondria. Journal of Cell Science 138 (9), jcs264067 (2025)
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A short intrinsically disordered region at KtrB’s N-terminus facilitates allosteric regulation of K+ channel KtrAB. Nature Communications 16, 4252 (2025)
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AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy. Autophagy 21 (10), S. 2192 - 2212 (2025)
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Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases. Molecular Aspects of Medicine 103, 101369 (2025)
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Cryo-EM of Mitochondrial Complex I and ATP Synthase. Annual Review of Biophysics 54, S. 209 - 226 (2025)
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DARPin-induced reactivation of p53 in HPV-positive cells. Nature Structural & Molecular Biology 32 (5), S. 790 - 801 (2025)
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Introducing Bonnie Murphy, Ville Kaila, Maxie Roessler, Volha Chukhutsina, Alisia Fadini, Sonya Hanson, Filipe Maia, and Kirill Kovalev. Structure 33 (5), S. 829 - 835 (2025)
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Nuclear pores safeguard the integrity of the nuclear envelope. Nature Cell Biology 27 (5), S. 762 - 775 (2025)
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Mechanisms of chemotherapy-induced oocyte death through activation of TAp63α. Reproduction: the Journal of the Society for Reproduction and Fertility 169 (5), e240225 (2025)
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Proteorhodopsin insights into the molecular mechanism of vectorial proton transport. Science Advances 11 (16), eadu5303 (2025)
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In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell 188 (8), S. 2094 - 2110.e18 (2025)
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MLKL activity requires a splicing-regulated, druggable intramolecular interaction. Molecular Cell 85 (8), S. 1589 - 1605 (2025)
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Structural pathway for PI3-kinase regulation by VPS15 in autophagy. Science 388 (6743), eadl3787 (2025)
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Enzymatic Birch reduction via hydrogen atom transfer at [4Fe-4S]-OH2 and [8Fe-9S] clusters. Nature Communications 16, 3236 (2025)
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The need to implement FAIR principles in biomolecular simulations. Nature Methods 22 (4), S. 641 - 645 (2025)
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The need to implement FAIR principles in biomolecular simulations. Nature Methods 22, S. 641 - 645 (2025)
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A novel biosensor for the spatiotemporal analysis of STING activation during innate immune responses to dsDNA. The EMBO Journal 44 (7), S. 2157 - 2182 (2025)
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Ferroptosis spreads to neighboring cells via plasma membrane contacts. Nature Communications 16, 2951 (2025)
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Impact of Lewis Acids on the Reactivity of a High-Valent Cu(III) Complex. Inorganic Chemistry 64 (11), S. 5734 - 5744 (2025)
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To degrade or not to degrade: how phase separation modulates selective autophagy. Autophagy 21 (11), S. 2518 - 2520 (2025)
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Retinitis pigmentosa-linked mutations impair the snRNA unwinding activity of SNRNP200 and reduce pre-mRNA binding of PRPF8. Cellular and Molecular Life Sciences 82, 103 (2025)
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MolecularWebXR: Multiuser discussions in chemistry and biology through immersive and inclusive augmented and virtual reality. Journal of Molecular Graphics and Modelling 135, 108932 (2025)
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Janus-like behavior of intrinsically disordered regions in reticulophagy. Autophagy 21 (3), S. 681 - 683 (2025)
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An engineered cereblon optimized for high throughput screening and molecular glue discovery. Cell Chemical Biology 32 (2), S. 363 - 376.e10 (2025)
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Passage of the HIV capsid cracks the nuclear pore. Cell 188 (4), S. 930 - 943.e21 (2025)
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Scaling of the GROMACS Molecular Dynamics Code to 65k CPU Cores on an HPC Cluster. Journal of Computational Chemistry 46 (5), e70059 (2025)
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Structural basis of anticancer drug recognition and amino acid transport by LAT1. Nature Communications 16, 1635 (2025)
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Nuclear pore permeability and fluid flow are modulated by its dilation state. Molecular Cell 85 (3), S. 537 - 554.e11 (2025)
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Molecular mechanism of condensin I activation by KIF4A. The EMBO Journal 44 (3), S. 682 - 704 (2025)
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Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy. Nature Cell Biology 27 (2), S. 283 - 297 (2025)
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In vitro dynamics of DNA loop extrusion by structural maintenance of chromosomes complexes. Current Opinion in Genetics & Development 90, 102284 (2025)
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Conformational dynamics of a multienzyme complex in anaerobic carbon fixation. Science 387 (6733), S. 498 - 504 (2025)
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A round table at IUPAB Congress in Kyoto 2024: Dreaming the next 50 years in our biophysics. Biophysics and Physicobiology 21 (Supplemental2), e212012 (2025)
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Ferroptosis triggers mitochondrial fragmentation via Drp1 activation. Cell Death and Disease 16, 40 (2025)
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In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor. Nature 637 (8047), S. 983 - 990 (2025)
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Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST. Science Advances 11 (4), eadu5787 (2025)
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Long-term single-molecule tracking in living cells using weak-affinity protein labeling. Angewandte Chemie, International Edition in English 64 (1), e202413117 (2025)