Publications of the Department of Molecular Sociology (MS)
Main keywords of publications are listed here:
Benchmarking tomographic acquisition schemes for high-resolution structural biology.
Turoňová B, Hagen WJH, Obr M, Mosalaganti S, Beugelink JW, Zimmerli CE, Kräusslich HG, Beck M.Nat Commun., 2020 [10.1038/s41467-020-14535-2]
Selective autophagy degrades nuclear pore complexes.
Lee CW, Wilfling F, Ronchi P, Allegretti M, Mosalaganti S, Jentsch S, Beck M, Pfander B. Nat Cell Biol., 2020 [10.1038/s41556-019-0459-2]
Fürsch J, Kammer KM, Kreft SG, Beck M, Stengel F.Anal Chem., 2020 [10.1021/acs.analchem.9b05559]
Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.
Guo T, Luna A, Rajapakse VN, Koh CC, Wu Z, Liu W, Sun Y, Gao H, Menden MP, Xu C, Calzone L, Martignetti L, Auwerx C, Buljan M, Banaei-Esfahani A, Ori A, Iskar M, Gillet L, Bi R, Zhang J, Zhang H, Yu C, Zhong Q, Varma S, Schmitt U, Qiu P, Zhang Q, Zhu Y, Wild PJ, Garnett MJ, Bork P, Beck M, Liu K, Saez-Rodriguez J, Elloumi F, Reinhold WC, Sander C, Pommier Y, Aebersold R. iScience., 2019 [10.1016/j.isci.2019]
Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis.
Hampoelz B, Schwarz A, Ronchi P, Bragulat-Teixidor H, Tischer C, Gaspar I, Ephrussi A, Schwab Y, Beck M.Cell, 2019 [10.1016/j.cell.2019.09.022]
The Benefits of Cotranslational Assembly: A Structural Perspective.
Schwarz A, Beck M.Trends Cell Biol., 2019 [10.1016/j.tcb.2019.07.006]
Nucleoporin Nup155 is part of the p53 network in liver cancer.
Holzer K, Ori A, Cooke A, Dauch D, Drucker E, Riemenschneider P, Andres-Pons A, DiGuilio AL, Mackmull MT, Baßler J, Roessler S, Breuhahn K, Zender L, Glavy JS, Dombrowski F, Hurt E, Schirmacher P, Beck M, Singer S. Nat Commun., 2019 [10.1038/s41467-019-10133-z]
Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals.
Romanov N, Kuhn M, Aebersold R, Ori A, Beck M, Bork P. Cell., 2019 [10.1016/j.cell.2019.03.015]
Structure and Assembly of the Nuclear Pore Complex.
Hampoelz B, Andres-Pons A, Kastritis P, Beck M. Annu Rev Biophys., 2019 [10.1146/annurev-biophys-052118-115308]
Thaller DJ, Allegretti M, Borah S, Ronchi P, Beck M, Lusk CP. Elife., 2019 [10.7554/eLife.45284]
Beck M, Mosalaganti S, Kosinski J. Curr Opin Struct Biol., 2018 [10.1016/j.sbi.2018.07.012]
Nuclear Pore Complex Components in the Malaria Parasite Plasmodium berghei.
Kehrer J, Kuss C, Andres-Pons A, Reustle A, Dahan N, Devos D, Kudryashev M, Beck M, Mair GR, Frischknecht F. Sci Rep., 2018 [10.1038/s41598-018-29590-5]
Quantifying compartment-associated variations of protein abundance in proteomics data.
Parca L, Beck M, Bork P, Ori A. Mol Syst Biol., 2018 [10.15252/msb.20178131]
In situ architecture of the algal nuclear pore complex.
Mosalaganti S, Kosinski J, Albert S, Schaffer M, Strenkert D, Salomé PA, Merchant SS, Plitzko JM, Baumeister W, Engel BD, Beck M. Nat Commun., 2018 [10.1038/s41467-018-04739-y]
Pervasive Protein Thermal Stability Variation during the Cell Cycle.
Becher I, Andrés-Pons A, Romanov N, Stein F, Schramm M, Baudin F, Helm D, Kurzawa N, Mateus A, Mackmull MT, Typas A, Müller CW, Bork P, Beck M, Savitski MM. Cell., 2018 [10.1016/j.cell.2018.03.053]
Systematic analysis of protein turnover in primary cells.
Mathieson T, Franken H, Kosinski J, Kurzawa N, Zinn N, Sweetman G, Poeckel D, Ratnu VS, Schramm M, Becher I, Steidel M, Noh KM, Bergamini G, Beck M, Bantscheff M, Savitski MM. Nat Commun., 2018 [10.1038/s41467-018-03106-1]
Buczak K, Ori A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer S, Beck M. Mol Cell Proteomics., 2018 [10.1074/mcp.RA117.000189]
Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings.
Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J. Nat Struct Mol Biol., 2018 [10.1038/s41594-017-0001-9]
Landscape of nuclear transport receptor cargo specificity.
Mackmull MT, Klaus B, Heinze I, Chokkalingam M, Beyer A, Russell RB, Ori A, Beck M. Mol Syst Biol., 2017 [10.15252/msb.20177608]
Proteasomes tether to two distinct sites at the nuclear pore complex.
Albert S, Schaffer M, Beck F, Mosalaganti S, Asano S, Thomas HF, Plitzko JM, Beck M, Baumeister W, Engel BD. Proc Natl Acad Sci U S A., 2017 [10.1073/pnas.1716305114]
Teimer R, Kosinski J, von Appen A, Beck M, Hurt E. Nat Commun., 2017 [10.1038/s41467-017-01160-9]
Capturing protein communities by structural proteomics in a thermophilic eukaryote.
Kastritis PL, O'Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, Beck M, Gavin AC. Mol Syst Biol., 2017 [10.15252/msb.20167412]
Structural insights into transcription initiation by yeast RNA polymerase I.
Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Müller CW. EMBO J., 2017 [10.15252/embj.201796958]
Beck M, Schirmacher P, Singer S. J Hepatol., 2017 [10.1016/j.jhep.2017.06.021]
The nuclear pore complex: understanding its function through structural insight.
Beck M, Hurt E. Nat Rev Mol Cell Biol., 2016 [10.1038/nrm.2016.147]
Architecture of the yeast Elongator complex.
Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW. EMBO Rep., 2016 [10.15252/embr.201643353]
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R. J Cell Biol., 2016 [10.1083/jcb.201601090]
Kiosze-Becker K, Ori A, Gerovac M, Heuer A, Nürenberg-Goloub E, Rashid UJ, Becker T, Beckmann R, Beck M, Tampé R. Nat Commun., 2016 [10.1038/ncomms13248]
Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail?
Beck M, Baumeister W. Trends Cell Biol., 2016 [10.1016/j.tcb.2016.08.006]
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope.
Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J. Elife., 2016 [10.7554/eLife.19071]
Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development.
Hampoelz B, Mackmull MT, Machado P, Ronchi P, Bui KH, Schieber N, Santarella-Mellwig R, Necakov A, Andrés-Pons A, Philippe JM, Lecuit T, Schwab Y, Beck M. Cell., 2016 [10.1016/j.cell.2016.06.015]
Toward the atomic structure of the nuclear pore complex: when top down meets bottom up.
Hoelz A, Glavy JS, Beck M. Nat Struct Mol Biol., 2016 [10.1038/nsmb.3244]
Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M. Cell Syst., 2016 [10.1016/j.cels.2015.08.012]
Automated structure modeling of large protein assemblies using crosslinks as distance restraints.
Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M, Simon B, Bouvier G, Batista PR, Müller CW, Beck M, Nilges M. Nat Methods., 2016 [10.1038/nmeth.3838]
Molecular architecture of the inner ring scaffold of the human nuclear pore complex.
Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuilio AL, Wan W, Bui KH, Hagen WJ, Briggs JA, Glavy JS, Hurt E, Beck M. Science., 2016 [10.1126/science.aaf0643]
Spatiotemporal variation of mammalian protein complex stoichiometries.
Ori A, Iskar M, Buczak K, Kastritis P, Parca L, Andrés-Pons A, Singer S, Bork P, Beck M. Genome Biol., 2016 [10.1186/s13059-016-0912-5]
Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy.
von Appen A, Beck M. J Mol Biol., 2016 [10.1016/j.jmb.2016.01.004]
Silva-Martin N, Daudén MI, Glatt S, Hoffmann NA, Kastritis P, Bork P, Beck M, Müller CW. PLoS One., 2016 [10.1371/journal.pone.0146457]
Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S, Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart DJ, Beck M, Cusack S. Mol Cell., 2015 [10.1016/j.molcel.2015.11.016]
Poli M, Ori A, Child T, Jaroudi S, Spath K, Beck M, Wells D. EMBO Mol Med., 2015 [10.15252/emmm.201505344]
In situ structural analysis of the human nuclear pore complex.
von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M. Nature., 2015 [10.1038/nature15381]
Deniaud A, Karuppasamy M, Bock T, Masiulis S, Huard K, Garzoni F, Kerschgens K, Hentze MW, Kulozik AE, Beck M, Neu-Yilik G, Schaffitzel C. Nucleic Acids Res., 2015 [10.1093/nar/gkv668]
Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Male G, von Appen A, Glatt S, Taylor NM, Cristovao M, Groetsch H, Beck M, Müller CW. Nat Commun., 2015 [10.1038/ncomms8387]
Hurt E, Beck M. Curr Opin Cell Biol., 2015 [10.1016/j.ceb.2015.04.009]
Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressler D, Bange G, Hurt E, Beck M, Sinning I. Nat Commun., 2015 [10.1038/ncomms7510]
Mackmull MT, Iskar M, Parca L, Singer S, Bork P, Ori A, Beck M. Mol Cell Proteomics., 2015 [10.1074/mcp.M114.042499]
Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M. J Struct Biol., 2015 [10.1016/j.jsb.2015.01.014]
Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.
Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E. J Cell Biol., 2015 [10.1083/jcb.201411003]
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.
Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, et al. Nucleic Acids Res., 2014 [10.1093/nar/gku1147]
Ostenfeld MS, Jeppesen DK, Laurberg JR, Boysen AT, Bramsen JB, Primdal-Bengtson B, Hendrix A, Lamy P, Dagnaes-Hansen F, Rasmussen MH, Bui KH, Fristrup N, Christensen EI, Nordentoft I, Morth JP, Jensen JB, Pedersen JS, Beck M, Theodorescu D, Borre M, Howard KA, Dyrskjøt L, et al. Cancer Res., 2014 [10.1158/0008-5472.CAN-13-3512]
The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies.
Ori A, Andrés-Pons A, Beck M. Methods Cell Biol., 2014 [10.1016/B978-0-12-417160-2.00006-0]
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits.
Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH. Nat Struct Mol Biol., 2014 [10.1038/nsmb.2831]
Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Bermejo JL, Gretz N, Zender L, Schirmacher P, Beck M, Singer S. Hepatology., 2014 [10.1002/hep.27207]
Toward understanding the structure of the vertebrate nuclear pore complex.
Beck M, Glavy JS. Nucleus., 2014 [10.4161/nucl.28739]
Integrated structural analysis of the human nuclear pore complex scaffold.
Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M. Cell., 2013 [10.1016/j.cell.2013.10.055]
Thierbach K, von Appen A, Thoms M, Beck M, Flemming D, Hurt E. Structure., 2013 [10.1016/j.str.2013.07.004]
Fourier ring correlation as a resolution criterion for super-resolution microscopy.
Banterle N, Bui KH, Lemke EA, Beck M. J Struct Biol., 2013 [10.1016/j.jsb.2013.05.004]
Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. Mol Syst Biol., 2013 [10.1038/msb.2013.4]
Facilitated aggregation of FG nucleoporins under molecular crowding conditions.
Milles S, Huy Bui K, Koehler C, Eltsov M, Beck M, Lemke EA. EMBO Rep., 2012 [10.1038/embor.2012.204]
Herzog F, Kahraman A, Boehringer D, Mak R, Bracher A, Walzthoeni T, Leitner A, Beck M, Hartl FU, Ban N, Malmström L, Aebersold R. Science., 2012 [10.1126/science.1221483]
False discovery rate estimation for cross-linked peptides identified by mass spectrometry.
Walzthoeni T, Claassen M, Leitner A, Herzog F, Bohn S, Förster F, Beck M, Aebersold R. Nat Methods., 2012 [10.1038/nmeth.2103]
Xu M, Beck M, Alber F. J Struct Biol., 2012 [10.1016/j.jsb.2012.02.014]
The quantitative proteome of a human cell line.
Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. Mol Syst Biol., 2011 [10.1038/msb.2011.82]
Absolute quantification of microbial proteomes at different states by directed mass spectrometry.
Schmidt A, Beck M, Malmström J, Lam H, Claassen M, Campbell D, Aebersold R. Mol Syst Biol., 2011 [10.1038/msb.2011.37]
Template-free detection of macromolecular complexes in cryo electron tomograms.
Xu M, Beck M, Alber F. Bioinformatics., 2011 [10.1093/bioinformatics/btr207]
mProphet: automated data processing and statistical validation for large-scale SRM experiments.
Reiter L, Rinner O, Picotti P, Hüttenhain R, Beck M, Brusniak MY, Hengartner MO, Aebersold R. Nat Methods., 2011 [10.1038/nmeth.1584]
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.
Bohn S, Beck F, Sakata E, Walzthoeni T, Beck M, Aebersold R, Förster F, Baumeister W, Nickell S. Proc Natl Acad Sci U S A., 2010 [10.1073/pnas.1015530107]
Exploring the spatial and temporal organization of a cell's proteome.
Beck M, Topf M, Frazier Z, Tjong H, Xu M, Zhang S, Alber F. J Struct Biol., 2010 [10.1016/j.jsb.2010.11.011]
Förster F, Han BG, Beck M. Methods Enzymol., 2010 [10.1016/S0076-6879(10)83011-3]
Beck M, Claassen M, Aebersold R. Curr Opin Biotechnol., 2010 [10.1016/j.copbio.2010.09.002]
Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics.
Leitner A, Walzthoeni T, Kahraman A, Herzog F, Rinner O, Beck M, Aebersold R. Mol Cell Proteomics., 2010 [10.1074/mcp.R000001-MCP201]
Visual proteomics of the human pathogen Leptospira interrogans.
Beck M, Malmström JA, Lange V, Schmidt A, Deutsch EW, Aebersold R. Nat Methods., 2009 [10.1038/nmeth.1390]
Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans.
Malmström J, Beck M, Schmidt A, Lange V, Deutsch EW, Aebersold R. Nature., 2009 [10.1038/nature08184]
Architecture and molecular mechanism of PAN, the archaeal proteasome regulatory ATPase.
Medalia N, Beer A, Zwickl P, Mihalache O, Beck M, Medalia O, Navon A. J Biol Chem., 2009 [10.1074/jbc.M809643200]
Structural and functional insights into nucleocytoplasmic transport.
Beck M, Medalia O. Histol Histopathol., 2008 [10.14670/HH-23.1025]
Identification of cross-linked peptides from large sequence databases.
Rinner O, Seebacher J, Walzthoeni T, Mueller LN, Beck M, Schmidt A, Mueller M, Aebersold R. Nat Methods., 2008 [10.1038/nmeth.1192]
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography.
Beck M, Lucić V, Förster F, Baumeister W, Medalia O. Nature., 2007 [10.1038/nature06170]
Organization of actin networks in intact filopodia.
Medalia O, Beck M, Ecke M, Weber I, Neujahr R, Baumeister W, Gerisch G. Curr Biol., 2007 [10.1016/j.cub.2006.11.022]
Luminal particles within cellular microtubules.
Garvalov BK, Zuber B, Bouchet-Marquis C, Kudryashev M, Gruska M, Beck M, Leis A, Frischknecht F, Bradke F, Baumeister W, Dubochet J, Cyrklaff M. J Cell Biol., 2006 [10.1083/jcb.200606074]
Nuclear pore complex structure and dynamics revealed by cryoelectron tomography.
Beck M, Förster F, Ecke M, Plitzko JM, Melchior F, Gerisch G, Baumeister W, Medalia O. Science., 2004 [10.1126/science.1104808]
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