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Publications in 2021
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High-end Instruments

Latest Publications

1.
Laube, E.; Schiller, J.; Zickermann, V.; Vonck, J.: Using cryo-EM to understand the assembly pathway of respiratory complex I. Acta Crystallographica Section D: Structural Biology (2024)
2.
Shukla, S.; Chen, W.; Rao, S.; Yang, S.; Ou, C.; Larsen, K. P.; Hummer, G.; Hanson, P. I.; Hurley, J. H.: Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca2+-sensor ALG-2. Proceedings of the National Academy of Sciences of the United States of America 121 (9), e2318046121 (2024)
3.
Vögele, M.; Köfinger, J.; Hummer, G.: Nanoporous Membranes of Densely Packed Carbon Nanotubes Formed by Lipid-Mediated Self-Assembly. ACS applied bio materials 7 (2), pp. 528 - 534 (2024)
4.
Bjarnason, S.; McIvor, J. A. P.; Prestel, A.; Demény, K. S.; Bullerjahn, J. T.; Kragelund, B. B.; Mercadante, D.; Heidarsson, P. O.: DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2. Nature Communications 15, 1445 (2024)
5.
Pietrek, L. M.; Stelzl, L. S.; Hummer, G.: Hierarchical Assembly of Single-Stranded RNA. Journal of Chemical Theory and Computation (2024)
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News

Our Research 

Ernst Bamberg – The Functional Analysis of Electrogenic Membrane Proteins
We focus on the molecular mechanism of rhodopsin-like ion pumps and channels, and on their optogenetic applications.
 
Martin Beck – Molecular Sociology
How do molecular modules act in concert to generate complex cellular functions?
Ulrich Ermler – Enzyme Mechanism
We are focused on the enzyme structure-based analysis of challenging biochemical processes in anaerobic biomass degradation.
 
Gerhard Hummer – Theoretical Biophysics
Our goal is to develop detailed and quantitative descriptions of key biomolecular processes, including energy conversion, molecular transport, signal transduction, and enzymatic catalysis.
Eugene Kim – Structure and Dynamics of Chromosomes
What are the universal principles that underlie chromosome organization across all forms of life?
Werner Kühlbrandt – Structural Biology
How can we make the most of cryo-electron microscopy for determining the structure and function of membrane protein complexes?
Melanie McDowell – Membrane Protein Biogenesis
What molecular mechanisms control the delivery and correct insertion of membrane proteins at the endoplasmic reticulum?
Hartmut Michel – Molecular Membrane Biology
How to generate and use structural information to investigate function and mechanisms of membrane protein complexes?
 
Bonnie Murphy – Redox and Metalloproteins
Understanding mechanism through structure
Beata Turoňová – Image Processing
Our software method development focuses on improving tomogram quality and integrating contextual information into subtomogram averaging routines.
Sonja Welsch – Electron Microscopy
Our state-of-the-art equipment, and technical and scientific user support allow for novel insights into biological structures and molecular mechanisms.
Florian Wilfling - Mechanisms of Cellular Quality Control
How is cargo selected and packed into autophagosomes?

Scientific Facilites

Sonja Welsch – Electron Microscopy
Our state-of-the-art equipment, and technical and scientific user support allow for novel insights into biological structures and molecular mechanisms.
Stephan Junek – Imaging
Our state-of-the-art light microscopes and photomanipulation setups, as well as our training offers and user support, enable advanced imaging for cutting-edge research.
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