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Publications in 2021
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High-end Instruments

Latest Publications

1.
Schmitt, L.; Lechtenberg, I.; Drießen, D.; Flores-Romero, H.; Skowron, M. A.; Sekeres, M.; Hoppe, J.; Krings, K. S.; Llewellyn, T. R.; Peter, C. et al.; Stork, B.; Qin, N.; Bhatia, S.; Nettersheim, D.; Fritz, G.; García-Sáez, A. J.; Müller, T. J. J.; Wesselborg, S.: Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2. Cell Death Discovery 10, 125 (2024)
2.
Blanc, F. E. C.; Hummer, G.: Mechanism of proton-powered c-ring rotation in a mitochondrial ATP synthase. PNAS 121 (11), e2314199121 (2024)
3.
Lasham, J.; Djurabekova, A.; Zickermann, V.; Vonck, J.; Sharma, V.: Role of Protonation States in the Stability of Molecular Dynamics Simulations of High-Resolution Membrane Protein Structures. The Journal of Physical Chemistry B (2024)
4.
Hoyer, M. J.; Capitanio, C.; Smith, I. R.; Paoli, J. C.; Bieber, A.; Jiang, Y.; Paulo, J. A.; Gonzalez-Lozano, M. A.; Baumeister, W.; Wilfling, F. et al.; Schulman, B. A.; Harper, J. W.: Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature Cell Biology (2024)
5.
Laube, E.; Schiller, J.; Zickermann, V.; Vonck, J.: Using cryo-EM to understand the assembly pathway of respiratory complex I. Acta Crystallographica Section D: Structural Biology (2024)
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News

Our Research 

Ernst Bamberg – The Functional Analysis of Electrogenic Membrane Proteins
We focus on the molecular mechanism of rhodopsin-like ion pumps and channels, and on their optogenetic applications.
 
Martin Beck – Molecular Sociology
How do molecular modules act in concert to generate complex cellular functions?
Ulrich Ermler – Enzyme Mechanism
We are focused on the enzyme structure-based analysis of challenging biochemical processes in anaerobic biomass degradation.
 
Gerhard Hummer – Theoretical Biophysics
Our goal is to develop detailed and quantitative descriptions of key biomolecular processes, including energy conversion, molecular transport, signal transduction, and enzymatic catalysis.
Eugene Kim – Structure and Dynamics of Chromosomes
What are the universal principles that underlie chromosome organization across all forms of life?
Werner Kühlbrandt – Structural Biology
How can we make the most of cryo-electron microscopy for determining the structure and function of membrane protein complexes?
Melanie McDowell – Membrane Protein Biogenesis
What molecular mechanisms control the delivery and correct insertion of membrane proteins at the endoplasmic reticulum?
Hartmut Michel – Molecular Membrane Biology
How to generate and use structural information to investigate function and mechanisms of membrane protein complexes?
 
Bonnie Murphy – Redox and Metalloproteins
Understanding mechanism through structure
Beata Turoňová – Image Processing
Our software method development focuses on improving tomogram quality and integrating contextual information into subtomogram averaging routines.
Sonja Welsch – Electron Microscopy
Our state-of-the-art equipment, and technical and scientific user support allow for novel insights into biological structures and molecular mechanisms.
Florian Wilfling - Mechanisms of Cellular Quality Control
How is cargo selected and packed into autophagosomes?

Scientific Facilites

Sonja Welsch – Electron Microscopy
Our state-of-the-art equipment, and technical and scientific user support allow for novel insights into biological structures and molecular mechanisms.
Stephan Junek – Imaging
Our state-of-the-art light microscopes and photomanipulation setups, as well as our training offers and user support, enable advanced imaging for cutting-edge research.
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