Publications of the Department of Molecular Membrane Biology

Grund, T. N.; Radloff, M.; Wu, D.; Goojani, H. G.; Witte, L. F.; Jösting, W.; Buschmann, S.; Müller, H.; Elamri, I.; Welsch, S. et al.; Schwalbe, H.; Michel, H.; Bald, D.; Safarian, S.: Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 118 (50), e2114013118 (2021)

Konia, E.; Chatzicharalampous, K.; Drakonaki, A.; Münke, C.; Ermler, U.; Tsiotis, G.; Pavlidis, I. V.: Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications 57 (96), pp. 12948 - 12951 (2021)

Radloff, M.; Elamri, I.; Grund, T. N.; Witte, L. F.; Hohmann, K. F.; Nakagaki, S.; Goojani , H. G.; Nasiri, H.; Miyoshi , H.; Bald, D. et al.; Xie, H.; Sakamoto, J.; Schwalbe, H.; Safarian, S.: Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases. Scientific Reports 11 (1), e23852 (2021)

Kolbe, F.; Safarian, S.; Piórek, Ż.; Welsch, S.; Müller, H.; Michel, H.: Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications 12, 6903 (2021)

Kung, J.; Meier, A.-K.; Willistein, M.; Weidenweber, S.; Demmer, U.; Ermler, U.; Boll, M.: Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem 22 (22), pp. 3172 - 3177 (2021)

Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)

Parey, K.; Lasham, J.; Mills, D. J.; Djurabekova, A.; Haapanen, O.; Yoga, E. G.; Xie, H.; Kühlbrandt, W.; Sharma, V.; Vonck, J. et al.; Zickermann, V.: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances 7 (46), eabj3221 (2021)

Mathioudaki, E.; Arvaniti, K.; Münke, C.; Drakonaki, A.; Vranakis, I.; Koutantou, M.; Psaroulaki, A.; Xie, H.; Tsiotis, G.: Expression, purification and characterization of the IcmG and IcmK proteins of the Type IVB secretion system from Coxiella burnetii. Protein Expression and Purification 186, 105905 (2021)

Safarian, S.; Opel-Reading, H. K.; Wu, D.; Mehdipour, A. R.; Hards, K.; Harold, L. H.; Radloff, M.; Stewart, I.; Welsch, S.; Hummer, G. et al.; Cook, G. M.; Krause, K. L.; Michel, H.: The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications 12 (1), 5236 (2021)

Nikolaev, A.; Safarian, S.; Thesseling, A.; Wohlwend, D.; Friedrich, T.; Michel, H.; Kusumoto, T.; Sakamoto, J.; Melin, F.; Hellwig, P.: Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics 1862 (8), e148436 (2021)

Kanavaki, I.; Drakonaki, A.; Geladas, E. D.; Spyros, A.; Xie, H.; Tsiotis, G.: Polyhydroxyalkanoate (PHA) Production in Pseudomonas sp. phDV1 Strain Grown on Phenol as Carbon Sources. Microorganisms 9 (8), 1636 (2021)

Zhu, G.; Zeng, H.; Zhang, S.; Juli, J.; Tai, L.; Zhang, D.; Pang , X.; Zhang, Y.; Lam, S. M.; Zhu, Y. et al.; Peng, G.; Michel, H.; Sun, F.: The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English 60 (24), pp. 13323 - 13330 (2021)

Kayastha, K.; Vitt, S.; Buckel, W.; Ermler, U.: Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics 701, 108796 (2021)

Appel, L.; Willistein, M.; Dahl, C.; Ermler, U.; Boll, M.: Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics 1862 (4), 148379 (2021)

Ernst, C.; Kayastha, K.; Koch , T.; Venceslau, S. S.; Pereira, I. A.C.; Demmer, U.; Ermler, U.; Dahl, C.: Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal 288 (5), pp. 1664 - 1678 (2021)

Psaroulaki, A.; Mathioudaki, E.; Vranakis, I.; Chochlakis, D.; Yachnakis, E.; Kokkini , S.; Xie, H.; Tsiotis, G.: In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes. Frontiers in Cellular and Infection Microbiology 10, 557027 (2020)

Wu, D.; Grund, T. N.; Welsch, S.; Mills, D.; Michel, M.; Safarian, S.; Michel, H.: Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America 117 (35), 202008111, pp. 21281 - 21287 (2020)

Elamri, I.; Radloff, M.; Hohmann, K. F.; Nimbarte, V. D.; Nasiri, H. R.; Bolte, M.; Safarian, S.; Michel, H.; Schwalbe, H.: Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo₃ Ubiquinol Oxidase from Escherichia coli. ChemMedChem 15 (14), pp. 1262 - 1271 (2020)

Zeng, H.; Zhu, G.; Zhang, S.; Li, X.; Martin, J.; Morgner, N.; Sun, F.; Peng, G.; Xie, H.; Michel, H.: Isolated Heme A Synthase from Aquifex aeolicus Is a Trimer. mBio 11 (3), e02615-19 (2020)

Neuhaus, A.; Selvaraj, M.; Salzer, R.; Langer, J. D.; Kruse, K.; Kirchner, L.; Sanders, K.; Daum, B.; Averhoff, B.; Gold, V.: Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium. Nature Communications 11, 2231 (2020)