Publications associated to Central Electron Microscopy Facility

High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding.

2019/07/11

Bykov YS, Cohen N, Gabrielli N, Manenschijn H, Welsch S, Chlanda P, Kukulski W, Patil KR, Schuldiner M, Briggs JAG. J Cell Biol., 2019 [10.1083/jcb.201812081]

Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.

2017

Bausewein T, Mills DJ, Langer JD, Nitschke B, Nussberger S, Kühlbrandt W. Cell. 2017 [10.1016/j.cell.2017.07.012]

Structure, mechanism, and regulation of the chloroplast ATP synthase.

2018

Hahn A, Vonck J, Mills DJ, Meier T, Kühlbrandt W. Science. 2018 [10.1126/science.aat4318]

2012/08/04

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. Methods Cell Biol., 2012 [10.1016/B978-0-12-416026-2.00013-3]

Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells.

2011/11/24

Bharat TA, Riches JD, Kolesnikova L, Welsch S, Krähling V, Davey N, Parsy ML, Becker S, Briggs JA. PLoS Biol., 2011 [10.1371/journal.pbio.1001196]

The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.

2011/09/13

Jolly C, Welsch S, Michor S, Sattentau QJ. PLoS Pathog., 2011 [10.1371/journal.ppat.1002226]

Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission.

2011/09/07

Beck R, Prinz S, Diestelkötter-Bachert P, Röhling S, Adolf F, Hoehner K, Welsch S, Ronchi P, Brügger B, Briggs JA, Wieland F. J Cell Biol., 2011 [10.1083/jcb.201011027]

Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.

2011/05/27

Welsch S, Groot F, Kräusslich HG, Keppler OT, Sattentau QJ. J Virol., 2011 [10.1128/JVI.00834-11]

2011/01/05

Kukulski W, Schorb M, Welsch S, Picco A, Kaksonen M, Briggs JA. J Cell Biol., 2011 [10.1083/jcb.201009037]

Hijacking cellular garbage cans.

2010/06/15

Welsch S, Locker JK. Cell Host Microbe., 2010 [10.1016/j.chom.2010.05.014]

Electron tomography reveals the steps in filovirus budding.

2010/05/06

Welsch S, Kolesnikova L, Krähling V, Riches JD, Becker S, Briggs JA. PLoS Pathog., 2010 [10.1371/journal.ppat.1000875]

Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition.

2010/01/22

Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ. J Virol., 2010 [10.1128/JVI.02651-09]

HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity.

2009/08/12

Müller B, Anders M, Akiyama H, Welsch S, Glass B, Nikovics K, Clavel F, Tervo HM, Keppler OT, Kräusslich HG. J Biol Chem., 2009 [10.1074/jbc.M109.027144]

Composition and three-dimensional architecture of the dengue virus replication and assembly sites.

2009/04/22

Welsch S, Miller S, Romero-Brey I, Merz A, Bleck CK, Walther P, Fuller SD, Antony C, Krijnse-Locker J, Bartenschlager R. Cell Host Microbe., 2009 [10.1016/j.chom.2009.03.007]

HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor.

2009/03/17

Goffinet C, Allespach I, Homann S, Tervo HM, Habermann A, Rupp D, Oberbremer L, Kern C, Tibroni N, Welsch S, Krijnse-Locker J, Banting G, Kräusslich HG, Fackler OT, Keppler OT. Cell Host Microbe., 2009 [10.1016/j.chom.2009.01.009]

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.

2008/02/26

Groot F, Welsch S, Sattentau QJ. Blood., 2008 [10.1182/blood-2007-12-130070]

More than one door - Budding of enveloped viruses through cellular membranes.

2007/04/17

Welsch S, Müller B, Kräusslich HG. FEBS Lett., 2007 [10.1016/j.febslet.2007.03.060]

HIV-1 buds predominantly at the plasma membrane of primary human macrophages.

2007/03/27

Welsch S, Keppler OT, Habermann A, Allespach I, Krijnse-Locker J, Kräusslich HG. PLoS Pathog., 2007 [10.1371/journal.ppat.0030036]

Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function.

2006/10/04

Welsch S, Habermann A, Jäger S, Müller B, Krijnse-Locker J, Kräusslich HG. Traffic., 2006 [10.1111/j.1600-0854.2006.00489.x]

Quantitative SUMO-1 modification of a vaccinia virus protein is required for its specific localization and prevents its self-association.

2005/04/01

Palacios S, Perez LH, Welsch S, Schleich S, Chmielarska K, Melchior F, Locker JK. Mol Biol Cell., 2005 [10.1091/mbc.e04-11-1005]

The vaccinia virus I3L gene product is localized to a complex endoplasmic reticulum-associated structure that contains the viral parental DNA.

2003/04/30

Welsch S, Doglio L, Schleich S, Krijnse Locker J. J Virol., 2003 [10.1128/jvi.77.10.6014-6028.2003]