Publications of Ulrich Ermler

Journal Article (142)

2024
Journal Article
Aziz, I.; Kayastha, K.; Kaltwasser, S.; Vonck, J.; Welsch, S.; Murphy, B. J.; Kahnt, J.; Wu, D.; Wagner, T.; Shima, S. et al.; Ermler, U.: Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis. PNAS 121 (14), e2315568121 (2024)
2023
Journal Article
Demmer, U.; Lemaire, O.; Belhamri, M.; Ermler, U.: Ethoxylate Polymer-Based 96-Well Screen for Protein Crystallization. Crystals 13, 1519 (2023)
Journal Article
Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Crystal structure of FAD-independent methylene-tetrahydrofolate reductase from Mycobacterium hassiacum. Proteins: Structure, Function, and Bioinformatics 91 (9), pp. 1329 - 1340 (2023)
2022
Journal Article
Vitt, S.; Prinz, S.; Eisinger, M. L.; Ermler, U.; Buckel, W.: Purification and structural characterization of the Na+-translocating ferredoxin: NAD+ reductase (Rnf) complex of Clostridium tetanomorphum. Nature Communications 13, 6315 (2022)
Journal Article
Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Münke, C.; Robinson, C. V.; Hummer, G.; Xie, H. et al.; Michel, H.: Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism. The EMBO Journal 41 (18), e109990 (2022)
Journal Article
Kayastha, K.; Katsyv, A.; Himmrich, C.; Welsch, S.; Schuller, J. M.; Ermler, U.; Müller, V.: Structure-based electron-confurcation mechanism of the Ldh-EtfAB complex. eLife 11, e77095 (2022)
Journal Article
Aziz, I.; Kaltwasser, S.; Kayastha, K.; Khera, R.; Vonck, J.; Ermler, U.: The molybdenum storage protein forms and deposits distinct polynuclear tungsten oxygen aggregates. Journal of Inorganic Biochemistry 234, 111904 (2022)
Journal Article
Weidenweber, S.; Schühle, K.; Lippert, M.-L.; Mock, J.; Seubert, A.; Demmer, U.; Ermler, U.; Heider, J.: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyses the final step of anaerobic toluene metabolism. The FEBS Journal 5, 166 (2022)
2021
Journal Article
Konia, E.; Chatzicharalampous, K.; Drakonaki, A.; Münke, C.; Ermler, U.; Tsiotis, G.; Pavlidis, I. V.: Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications 57 (96), pp. 12948 - 12951 (2021)
Journal Article
Kung, J.; Meier, A.-K.; Willistein, M.; Weidenweber, S.; Demmer, U.; Ermler, U.; Boll, M.: Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem 22 (22), pp. 3172 - 3177 (2021)
Journal Article
Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)
Journal Article
Kayastha, K.; Vitt, S.; Buckel, W.; Ermler, U.: Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics 701, 108796 (2021)
Journal Article
Appel, L.; Willistein, M.; Dahl, C.; Ermler, U.; Boll, M.: Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics 1862 (4), 148379 (2021)
Journal Article
Ernst, C.; Kayastha, K.; Koch , T.; Venceslau, S. S.; Pereira, I. A.C.; Demmer, U.; Ermler, U.; Dahl, C.: Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal 288 (5), pp. 1664 - 1678 (2021)
2020
Journal Article
Shima, S.; Huang, G.; Wagner, T.; Ermler, U.: Structural Basis of Hydrogenotrophic Methanogenesis. Annual Review of Microbiology 74, pp. 713 - 733 (2020)
Journal Article
Vitt, S.; Prinz, S.; Hellwig, N.; Morgner, N.; Ermler, U.; Buckel, W.: Molecular and Low-Resolution Structural Characterization of the Na+-Translocating Glutaconyl-CoA Decarboxylase From Clostridium symbiosum. Frontiers in Microbiology 11, 480 (2020)
Journal Article
Huang, G.; Wagner, T.; Demmer, U.; Warkentin, E.; Ermler, U.; Shima, S.: The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. Journal of Molecular Biology (London) 432 (7), pp. 2042 - 2054 (2020)
Journal Article
Huang, G.; Wagner, T.; Ermler, U.; Shima, S.: Methanogenesis involves direct hydride transfer from H2 to an organic substrate. Nature Reviews Chemistry 4 (2), pp. 213 - 221 (2020)
2019
Journal Article
Brünle, S.; Eisinger, M. L.; Poppe, J.; Mills, D. J.; Langer, J. D.; Vonck, J.; Ermler, U.: Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism. Proceedings of the National Academy of Sciences of the United States of America 52 (116), pp. 26497 - 26504 (2019)
Journal Article
Huang, G.; Wagner, T.; Wodrich, M. D.; Ataka, K.; Bill, E.; Ermler, U.; Hu, X.; Shima, S.: The atomic-resolution crystal structure of activated [Fe]-hydrogenase. Nature Catalysis 2 (6), pp. 537 - 543 (2019)
Journal Article
Willistein, M.; Bechtel, D. F.; Müller, C. S.; Demmer, U.; Heimann, L.; Kayastha, K.; Schünemann, V.; Pierik, A. J.; Ullmann, G. M.; Ermler, U. et al.; Boll, M.: Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactorsLow potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors. Nature Communications 10, 2074 (2019)
Journal Article
Watanabe, T.; Wagner, T.; Huang, G.; Kahnt, J.; Ataka, K.; Ermler, U.; Shima, S.: The Bacterial [Fe]‐Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angewandte Chemie International Edition in English 58 (11), pp. 3506 - 3510 (2019)
2018
Journal Article
Poppe, J.; Brünle, S.; Hail, R.; Wiesemann, K.; Schneider, K.; Ermler, U.: The Molybdenum Storage Protein: A soluble ATP hydrolysis‐dependent molybdate pump. The FEBS Journal 285 (24), pp. 4602 - 4616 (2018)
Journal Article
Brünle, S.; Poppe, J.; Hail, R.; Demmer, U.; Ermler, U.: The molybdenum storage protein - A bionanolab for creating experimentally alterable polyoxomolybdate clusters. Journal of Inorganic Biochemistry 189 (12), pp. 172 - 179 (2018)
Journal Article
Wagner , T.; Huang, G.; Ermler, U.; Shima, S.: How [Fe]-Hydrogenase from Methanothermobacter is Protected Against Light and Oxidative Stress. Angewandte Chemie International Edition in English 57 (46), pp. 15056 - 15059 (2018)
Journal Article
Huang, G.; Wagner, T.; Ermler, U.; Bill, E.; Ataka, K.; Shima, S.: Dioxygen Sensitivity of [Fe]‐Hydrogenase in the Presence of Reducing Substrates. Angewandte Chemie International Edition in English 57 (18), pp. 4917 - 4920 (2018)
Journal Article
Demmer, J. K.; Bertsch, J.; Öppinger, C.; Wohlers, H.; Kayastha, K.; Demmer, U.; Ermler, U.; Müller, V.: Molecular basis of the flavin‐based electron‐bifurcating caffeyl‐CoA reductase reaction. FEBS Letters 592 (3), pp. 332 - 342 (2018)
2017
Journal Article
Demmer, J. K.; Chowdhury, N. P.; Selmer, T.; Ermler, U.; Buckel, W.: The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile. Nature Communications 8, 1577 (2017)
Journal Article
Warkentin, E.; Weidenweber, S.; Schühle, K.; Demmer, U.; Heider, J.; Ermler, U.: A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins: Structure, Function, and Bioinformatics 85 (11), pp. 2017 - 2023 (2017)
Journal Article
Weinert, T.; Olieric, N.; Cheng, R.; Brünle, S.; James, D.; Ozerov, D.; Gashi, D.; Vera, L.; Marsh, M.; Jaeger, K. et al.; Dworkowski, F.; Panepucci, E.; Basu, S.; Skopintsev, P.; Dorè, A. S.; Geng, T.; Cooke, R. M.; Liang, M.; Prota, A. E.; Paneels, V.; Nogly, P.; Ermler, U.; Schertler, G.; Hennig, M.; Steinmetz, M. O.; Wang, M.; Standfuss, J.: Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nature Communications 8, 542 (2017)
Journal Article
Bai, L.; Wagner, T.; Xu, T.; Hu, X.; Ermler, U.; Shima, S.: A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angewandte Chemie, International Edition in English 56 (36), pp. 10806 - 10809 (2017)
Journal Article
Wagner, T.; Koch, J.; Ermler, U.; Shima, S.: Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science 357 (6352), pp. 699 - 703 (2017)
Journal Article
Bai, L.; Fujishiro, T.; Huang, G.; Koch , J.; Takabayashi, A.; Yokono , M.; Tanaka , A.; Xu, T.; Hu , X.; Ermler, U. et al.; Shima , S.: Towards artificial methanogenesis: biosynthesis of the [Fe]-hydrogenase cofactor and characterization of the semi-synthetic hydrogenase. Faraday Discussions 198 (37), pp. 37 - 58 (2017)
Journal Article
Konjik, V.; Brünle, S.; Demmer, U.; Vanselow, A.; Sandhoff, R.; Ermler, U.; Mack, M.: The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angewandte Chemie, International Edition in English 56 (4), pp. 1146 - 1151 (2017)
Journal Article
Weidenweber, S.; Schühle, K.; Demmer, U.; Warkentin, E.; Ermler, U.; Heider, J.: Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Scientific Reports 7, 39674 (2017)
2016
Journal Article
Demmer, J. K.; Rupprecht, F. A.; Eisinger, M. L.; Ermler, U.; Langer, J. D.: Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. FEBS Letters 590 (24), pp. 4472 - 4479 (2016)
Journal Article
Wagner , T.; Ermler, U.; Shima, S.: The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters. Science Magazine 354 (6308), pp. 114 - 117 (2016)
Journal Article
Upadhyay, V.; Ceh, K.; Tumulka, F.; Abele, R.; Hoffmann , J.; Langer, J. D.; Shima, S.; Ermler, U.: Molecular characterization of methanogenic N5-methyltetrahydromethanopterin: Coenzyme M methyltransferase. Biochimica et Biophysica Acta-Biomembranes 1858 (9), pp. 2140 - 2144 (2016)
Journal Article
Wagner, T.; Kahnt, J.; Ermler, U.; Shima, S.: Didehydroaspartate Modification in Methyl-Coenzyme M Reductase Catalyzing Methane Formation. Angewandte Chemie International Edition in English 55 (36), pp. 10630 - 10633 (2016)
Journal Article
Fujishiro, T.; Bai , L.; Xu , T.; Xie , X.; Schick, M.; Kahnt, J.; Rother, M.; Hu , X.; Ermler, U.; Shima, S.: Identification of HcgC as a SAM-Dependent Pyridinol Methyltransferase in [Fe]-Hydrogenase Cofactor Biosynthesis. Angewandte Chemie International Edition in English 55 (33), pp. 9648 - 9651 (2016)
Journal Article
Wagner, T.; Ermler, U.; Shima, S.: MtrA of the sodium ion pumping methyltransferase binds cobalamin in a unique mode. Scientific Reports 6, 28226 (2016)
Journal Article
Weidenweber, S.; Marmulla, R.; Ermler, U.; Harder, J.: X-ray structure of linalool dehydratase/isomerase from Castellaniella defragrans reveals enzymatic alkene synthesis. FEBS Letters 590 (9), pp. 1375 - 1383 (2016)
Journal Article
Boll, M.; Einsle, O.; Ermler, U.; Kroneck, P. M.H.: Structure and Function of the Unusual Tungsten Enzymes Acetylene Hydratase and Class II Benzoyl-Coenzyme A Reductase. Journal of Molecular Microbiology and Biotechnology 26 (1-3), pp. 119 - 137 (2016)
Journal Article
Boll, M.; Kung, J. W.; Ermler, U.; Martins, B. M.; Buckel, W.: Fermentative Cyclohexane Carboxylate Formation in Syntrophus aciditrophicus. Journal of Molecular Microbiology and Biotechnology 26 (1-3), pp. 165 - 179 (2016)
Journal Article
Rabus, R.; Boll , M.; Heider, J.; Meckenstock, R. U.; Buckel, W.; Einsle, O.; Ermler, U.; Golding, B. T.; Gunsalus, R. P.; Kroneck, P. M.H. et al.; Krüger, M.; Lueders, T.; Martins, B. M.; Musat, F.; Richnow, H. H.; Schink, B.; Seifert, J.; Szaleniec, M.; Treude, T.; Ullmann, G. M.; Vogt, C.; von Bergen, M.; Wilkes, H.: Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment. Journal of Molecular Microbiology and Biotechnology 26 (1-3), pp. 5 - 28 (2016)
2015
Journal Article
Demmer, J. K.; Huang, H.; Wang, S.; Demmer, U.; Thauer, R. K.; Ermler, U.: Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure. The Journal of Biological Chemistry 290 (36), pp. 21985 - 21885 (2015)
Journal Article
Fujishiro, T.; Ataka, K.; Ermler, U.; Shima, S.: Towards a functional identification of catalytically inactive [Fe]-hydrogenase paralogs. FEBS Journal 282 (17), pp. 3412 - 3423 (2015)
Journal Article
Weinert, T.; Huwiler, S.; Kung, J. W.; Weidenweber, S.; Hellwig, P.; Stärk, H.-J.; Biskup, T.; Weber, S.; Cotelesage, J. J.H.; George, G. N. et al.; Ermler, U.; Boll, M.: Structural basis of enzymatic benzene ring reduction. Nature Chemical Biology 11 (8), pp. 586 - 591 (2015)
Journal Article
Fujishiro, T.; Kahnt, J.; Ermler, U.; Shima, S.: Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor. Nature Communications 6, e6895 (2015)
Journal Article
Rekittke, I.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the GcpE-HMBPP complex from Thermus thermophilius. Biochemical and Biophysical Research Communications 458 (2), pp. 246 - 250 (2015)
2014
Journal Article
Poppe, J.; Warkentin, E.; Demmer, U.; Kowalewski, B.; Dierks, T.; Schneider, K.; Ermler, U.: Structural diversity of polyoxomolybdate clusters along the three-fold axis of the molybdenum storage protein. Journal of Inorganic Biochemistry 138, pp. 122 - 128 (2014)
Journal Article
Fujishiro, T.; Ermler, U.; Shima, S.: A possible iron delivery function of the dinuclear iron center of HcgD in [Fe]-hydrogenase cofactor biosynthesis. FEBS Letters 588 (17), pp. 2789 - 2793 (2014)
Journal Article
Vitt, S.; Ma, K.; Warkentin, E.; Moll, J.; Pierik, A. J.; Shima, S.; Ermler, U.: The F420-Reducing [NiFe]-Hydrogenase Complex from Methanothermobacter marburgensis, the First X-ray Structure of a Group 3 Family Member. Journal of Molecular Biology (London) 426 (15), pp. 2813 - 2826 (2014)
Journal Article
Buschmann, S.; Richers, S.; Ermler, U.; Michel, H.: A decade of crystallization drops: Crystallization of the cbb3 cytochrome c oxidase from Pseudomonas stutzeri. Protein Science 23 (4), pp. 411 - 422 (2014)
Journal Article
Chowdhury, N. P.; Mowafy, A. M.; Demmer, J. K.; Upadhyay, V.; Koelzer, S.; Jayamani, E.; Kahnt, J.; Hornung, M.; Demmer, U.; Ermler, U. et al.; Buckel, W.: Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans. The Journal of Biological Chemistry 289 (8), pp. 5145 - 5157 (2014)
2013
Journal Article
Rekittke, I.; Olkhova, E.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum. FEBS Letters 587 (24), pp. 3968 - 3972 (2013)
Journal Article
Fielding, A. J.; Parey, K.; Ermler, U.; Scheller, S.; Jaun, B.; Bennati, M.: Advanced electron paramagnetic resonance on the catalytic iron–sulfur cluster bound to the CCG domain of heterodisulfide reductase and succinate: quinone reductase. Journal of Biological Inorganic Chemistry 18 (8), pp. 905 - 915 (2013)
Journal Article
Fujishiro, T.; Tamura, H.; Schick, M.; Kahnt, J.; Xie, X.; Ermler, U.; Shima, S.: Identification of the HcgB Enzyme in [Fe]-Hydrogenase-Cofactor Biosynthesis. Angewandte Chemie, International Edition in English 52 (48), pp. 12555 - 12558 (2013)
Journal Article
Parey, K.; Demmer, U.; Warkentin, E.; Wynen, A.; Ermler, U.; Dahl, C.: Structural, Biochemical and Genetic Characterization of Dissimilatory ATP Sulfurylase from Allochromatium vinosum. PLoS One 8 (9), p. e74707 - e74707 (2013)
Journal Article
Tamura, H.; Salomone-Stagni, M.; Fujishiro, T.; Warkentin, E.; Meyer-Klaucke, W.; Ermler, U.; shima, S.: Crystal Structures of [Fe]-Hydrogenase in Complex with Inhibitory Isocyanides: Implications for the H2-Activation Site. Angewandte Chemie, International Edition in English 52 (37), pp. 9656 - 9659 (2013)
Journal Article
Parey, K.; Fritz, G.; Ermler, U.; Kroneck, P. M. H.: Conserving energy with sulfate around 100 °C - structure and mechanism of key metal enzymes in hyperthermophilic Archaeoglobus fulgidus. Metallomics 5 (4), pp. 302 - 317 (2013)
Journal Article
Demmer, U.; Warkentin, E.; Srivastava, A.; Kockelkorn, D.; Pötter, M.; Marx, A.; Fuchs, G.; Ermler, U.: Structural Basis for a Bispecific NADP+ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase. The Journal of Biological Chemistry 288 (9), pp. 6363 - 6370 (2013)
2012
Journal Article
El Hammi, E.; Warkentin, E.; Demmer, U.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Active site analysis of yeast flavohemoglobin based on its structure with a small ligand or econazole. The FEBS Journal 279 (24), pp. 4565 - 4575 (2012)
Journal Article
Upadhyay, V.; Demmer, U.; Warkentin, E.; Moll, J.; Shima, S.; Ermler, U.: Structure and Catalytic Mechanism of N5,N10-Methenyltetrahydromethanopterin Cyclohydrolase. Biochemistry 51 (42), pp. 8435 - 8443 (2012)
Journal Article
Rekittke, I.; Jomaa, H. H.; Ermler, U.: Structure of the GcpE (IspG)-MEcPP complex from Thermus thermophilus. FEBS Letters 586 (19), pp. 3452 - 3457 (2012)
Journal Article
Shima, S.; Ermler, U.: Crystal structure and biochemistry of methyl-coenzyme M reductase from Black Sea mats mediating anaerobic oxidation of methane. Biseibutsu Seitai 27 (2), pp. 55 - 62 (2012)
Journal Article
Kowalewski, B.; Poppe, J.; Demmer, U.; Warkentin, E.; Dierks, T.; Ermler, U.; Schneider, K.: Nature’s Polyoxometalate Chemistry: X-ray Structure of the Mo Storage Protein Loaded with Discrete Polynuclear Mo−O Clusters. The Journal of Physical Chemistry A 134 (23), pp. 9768 - 9774 (2012)
Journal Article
Steinbach, A.; Fraas, S.; Harder, J.; Warkentin, E.; Kroneck, P. M. H.; Ermler, U.: Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family. The FEBS Journal 279 (7), pp. 1209 - 1219 (2012)
Journal Article
Shima, S.; Krueger, M.; Weinert, T.; Demmer, U.; Kahnt, J.; Thauer, R. K.; Ermler, U.: Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically. Nature 481 (7379), pp. 98 - 101 (2012)
2011
Journal Article
Steinbach, A. K.; Fraas, S.; Harder, J.; Tabbert, A.; Brinkmann, H.; Meyer, A.; Ermler, U.; Kroneck, P. M. H.: Cyclohexane-1,2-Dione Hydrolase from Denitrifying Azoarcus sp. Strain 22Lin, a Novel Member of the Thiamine Diphosphate Enzyme Family. Journal of Bacteriology 193 (23), pp. 6760 - 6769 (2011)
Journal Article
Rather, L. J.; Weinert, T.; Demmer, U.; Bill, E.; Ismail, W.; Fuchs, G.; Ermler, U.: Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB. The Journal of Biological Chemistry 286 (33), pp. 29241 - 29248 (2011)
Journal Article
Shima, S.; Ermler, U.: Structure and Function of [Fe]-Hydrogenase and its Iron–Guanylylpyridinol (FeGP) Cofactor. European Journal of Inorganic Chemistry 2011 (7), pp. 963 - 972 (2011)
Journal Article
Barthelme, D.; Dinkelaker, S.; Albers, S.-V.; Londei, P.; Ermler, U.; Tampé, R.: Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1. Proceedings of the National Academy of Sciences of the United States of America 108 (8), pp. 3228 - 3233 (2011)
Journal Article
El Hammi, E.; Warkentin, E.; Demmer, U.; Limam, F.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds. Biochemistry 50 (7), pp. 1255 - 1264 (2011)
Journal Article
Rekittke, I.; Nonaka, T.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus. FEBS Letters 585 (3), pp. 447 - 451 (2011)
2010
Journal Article
Parey, K.; Warkentin, E.; Kroneck, P. M.; Ermler, U.: Reaction Cycle of the Dissimilatory Sulfite Reductase from Archaeoglobus fulgidus. Biochemistry 49 (41), pp. 8912 - 8921 (2010)
Journal Article
Buschmann, S.; Warkentin, E.; Xie, H.; Langer, J. D.; Ermler, U.; Michel, H.: The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping. Science 329 (5989), pp. 327 - 330 (2010)
Journal Article
Rajendran, C.; Ermler, U.; Ludwig, B.; Michel, H.: Structure at 1.5 Å resolution of cytochrome c552 with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D66 (7), pp. 850 - 854 (2010)
Journal Article
Wischgoll, S.; Demmer, U.; Warkentin, E.; Günther, R.; Boll, M.; Ermler, U.: Structural Basis for Promoting and Preventing Decarboxylation in Glutaryl-Coenzyme A Dehydrogenases. Biochemistry 49 (25), pp. 5350 - 5357 (2010)
Journal Article
Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: A new structure-based classification of sulfide:quinone oxidoreductases. Proteins: Structure, Function, and Bioinformatics 78 (5), pp. 1073 - 1083 (2010)
2009
Journal Article
Fraas, S.; Steinbach, A. K.; Tabbert, A.; Harder, J.; Ermler, U.; Tittmann, K.; Meyer, A.; Kroneck, P. M.H.: Cyclohexane-1,2-dione hydrolase: A new tool to degrade alicyclic compounds. Journal of Molecular Catalysis B: Enzymatic 61 (1-2), pp. 47 - 49 (2009)
Journal Article
Ceh, K.; Demmer, U.; Warkentin, E.; Moll, J.; Thauer, R. K.; Shima, S.; Ermler, U.: Structural Basis of the Hydride Transfer Mechanism in F420-Dependent Methylenetetrahydromethanopterin Dehydrogenase. Biochemistry 49 (42), pp. 10098 - 10105 (2009)
Journal Article
Hiromoto, T.; Warkentin, E.; Moll, J.; Ermler, U.; Shima, S.: The Crystal Structure of an [Fe]-Hydrogenase-Substrate Complex Reveals the Framework for H2 Activation. Angewandte Chemie, International Edition in English 48 (35), pp. 6457 - 6460 (2009)
Journal Article
Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proceedings of the National Academy of Sciences of the United States of America 106 (24), pp. 9625 - 9630 (2009)
Journal Article
Hiromoto, T.; Ataka, K.; Pilak, O.; Vogt, S.; Stagni, M. S.; Meyer-Klaucke, W.; Warkentin, E.; Thauer, R. K.; Shima, S.; Ermler, U.: The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex. FEBS Letters 583 (3), pp. 585 - 590 (2009)
2008
Journal Article
Shima, S.; Pilak, O.; Vogt, S.; Schick, , M.; Stagni, M. S.; Meyer-Klauke, W.; Warkentin, E.; Thauer, R. K.; Ermler, U.: The Crystal Structure of [Fe]-Hydrogenase Reveals the Geometry of the Active Site. Science 321 (5888), pp. 572 - 575 (2008)
Journal Article
Schiffer, A.; Parey, K.; Warkentin, E.; Diederichs, K.; Huber, H.; Stetter, K. O.; Kroneck, P. M. H.; Ermler, U.: Structure of the Dissimilatory Sulfite Reductase from the Hyperthermophilic Archaeon Archaeoglobus fulgidus. Journal of Molecular Biology (London) 379 (5), pp. 1063 - 1074 (2008)
Journal Article
Jörg, J.; Unciuleac, M.-C.; Friedrich, T.; Warkentin, E.; Ermler, U.; Boll, M.: Inhibitors of the Molybdenum Cofactor Containing 4-Hydroxybenzoyl-CoA Reductase. Biochemistry 47 (17), pp. 4964 - 4972 (2008)
2007
Journal Article
Schemberg, J.; Schneider, K.; Demmer, U.; Warkentin, E.; Müller, A.; Ermler, U.: Towards Biological Supramolecular Chemistry: A Variety of Pocket-Templated Metal Oxide Cluster Nucleations in the Cavity of a Mo/W-Storage Protein. Angewandte Chemie, International Edition in English 46 (14), pp. 2408 - 2413 (2007)
Journal Article
Seedorf, H.; Hagemeier, C. H.; Shima, S.; Thauer, R. K.; Warkentin, E.; Ermler, U.: Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalysing the reduction of O2 to H2O. The FEBS Journal 274 (6), pp. 1588 - 1599 (2007)
Journal Article
de Olivereira, P.; Ranjbari, A.; Baciou, L.; Bizouarn, T.; Ollesch, G.; Ermler, U.; Sebban, P.; Keita, B.; Nadjo, L.: Preliminary electrochemical studies of the flavohaemoprotein from Ralstonia eutropha entrapped in a film of methyl cellulose: activation of the reduction of dioxygen. Bioelectrochemistry 70 (1), pp. 185 - 191 (2007)
2006
Journal Article
Hagemeier, C. H.; Krüer, M.; Thauer, R.; Warkentin, E.; Ermler, U.: Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America 103 (50), pp. 18917 - 18922 (2006)
Journal Article
Pilak, O.; Mamat, B.; Vogt, S.; Hagemeier, C. H.; Thauer, R. K.; Shima, S.; Vonrhein, C.; Warkentin, E.; Ermler, U.: The Crystal Structure of the Apoenzyme of the Iron-Sulphur Cluster-free Hydrogenase. Journal of Molecular Biology (London) 358 (3), pp. 798 - 809 (2006)
Journal Article
Acharya, P.; Warkentin, E.; Ermler, U.; Thauer, R. K.; Shima, S.: The structure of a Formylmethanofuran: Tetrahydromethanopterin Formyltransferase in Complex with its Coenzymes. Journal of Molecular Biology (London) 357 (3), pp. 870 - 879 (2006)
Journal Article
Schiffer, A.; Fritz, G.; Kroneck, P. M.H.; Ermler, U.: Reaction Mechanism of the Iron-Sulfur Flavoenzyme Adenosine-5 '-Phosphosulfate Reductase Based on the Structural Characterization of Different Enzymatic States. Biochemistry 45 (9), pp. 2960 - 2967 (2006)
2005
Journal Article
Mander, G. J.; Weiss, M. S.; Hedderich, R.; Kahnt, J.; Ermler, U.; Warkentin, E.: X-ray structure of the γ-subunit of a dissimilatory sulfite reductase: Fixed and flexible C-terminal arms. FEBS Letters 579 (21), pp. 4600 - 4604 (2005)
Journal Article
Aufhammer, S. W.; Warkentin, E.; Ermler, U.; Hagemeier, C. H.; Thauer, R. K.; Shima, S.: Crystal structure of methylenetetrahydromethanopterin (Mer) in complex with coenzyme F420: Architecture of the F420/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family. Protein Science 14 (7), pp. 1840 - 1849 (2005)
Journal Article
Scheffel, F.; Warkentin, E.; Hülsmann, A.; Schneider, E.; Ermler, U.: Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius. FEBS Letters 579 (13), pp. 2953 - 2958 (2005)
Journal Article
Acharya, P.; Gornrich, M.; Hagemeier, C.; Vorholt, J. A.; Thauer, R. K.; Ermler, U.: How an Enzyme Binds the C1 Carrier Tetrahydromethanopterin. Structure of the Tetrahydromethanopterin-Dependent Formaldehyde-Activating Enzyme (Fae) from Methylobacterium extorquens AM1. The Journal of Biological Chemistry 280 (14), pp. 13712 - 13719 (2005)
Journal Article
Ermler, U.: On the mechanism of methyl-coenzyme M reductase. Dalton Transactions 21, pp. 3451 - 3458 (2005)
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