Werner Kühlbrandt: Structural Biology – Department Publications

Journal Article (28)

2014
Journal Article
Paulino, C.; Wöhlert, D.; Kapotova, E.; Yildiz, Ö.; Kühlbrandt, W.: Structure and transport mechanism of the sodium/proton antiporter MjNhaP1. eLife 3, e03583 (2014)
Journal Article
Wöhlert, D.; Kühlbrandt, W.; Yildiz, Ö.: Structure and substrate ion binding in the sodium/proton antiporter PaNhaP. eLife 3, e03579 (2014)
Journal Article
Busch, A. P.; Rhinow, D.; Yang, F.; Reinhardt, H.; Beyer, A.; Gölzhäuser, A.; Hampp, N.: Site-selective biomineralization of native biological membranes. Journal of Materials Chemistry B 2, pp. 6924 - 6930 (2014)
Journal Article
Patwardhan, A.; Ashton, A.; Brandt, R.; Butcher, S.; Carzaniga, R.; Chiu, W.; Collison, L.; Doux, P.; Duke, E.; Ellisman, M. H. et al.; Franken, E.; Grünewald, K.; Heriche, J.-K.; Koster, A.; Kühlbrandt, W.; Lagerstedt, I.; Larabell, C.; Lawson, C. L.; Saibil, H. R.; Sanz-García, E.; Subramaniam, S.; Verkade, P.; Swedlow, J. R.; Kleywegt, G. J.: A 3D cellular context for the macromolecular world. Nature Structural and Molecular Biology 21 (10), pp. 841 - 845 (2014)
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Kühlbrandt, W.: Microscopy: Cryo-EM enters a new era. eLife 3, e03678 (2014)
Journal Article
Aktas, M.; Köster, S.; Kizilirmak, S.; Casanova, J. C.; Betz, H.; Fritz, C.; Moser, R.; Yildiz, Ö.; Narberhaus, F.: Enzymatic properties and substrate specificity of a bacterial phosphatidylcholine synthase. The FEBS Journal 281 (15), pp. 3523 - 3541 (2014)
Journal Article
Salzer, R.; Kern, T.; Joos, F.; Averhoff, B.: Environmental factors affecting the expression of type IV pilus genes as well as piliation of Thermus thermophilus. FEMS Microbiology Letters 357 (1), pp. 56 - 62 (2014)
Journal Article
Perez, C.; Faust, B.; Mehdipour, A. R.; Francesconi, K. A.; Forrest, L. R.; Ziegler, C.: Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling. Nature Communications 5, 4231 (2014)
Journal Article
Gold, V. A. M.; Ieva, R.; Walter, A.; Pfanner, N.; van der Laan, M.; Kühlbrandt, W.: Visualizing active membrane protein complexes by electron cryotomography. Nature Communications 5, 4129 (2014)
Journal Article
Preiss, L.; Langer, J. D.; Hicks, D. B.; Liu, J.; Yildiz, Ö.; Krulwich, T. A.; Meier, T.: The c-ring ion binding site of the ATP synthase from Bacillus pseudofirmus OF4 is adapted to alkaliphilic lifestyle. Molecular Microbiology 92 (5), pp. 973 - 984 (2014)
Journal Article
Sand, M.; Stahl, J.; Waclawska, I.; Ziegler, C.; Averhoff, B.: Identification of an osmo-dependent and an osmo-independent choline transporter in Acinetobacter baylyi: implications in osmostress protection and metabolic adaptation. Environmental Microbiology 16 (6), pp. 1490 - 1502 (2014)
Journal Article
Călinescu, O.; Paulino, C.; Kühlbrandt, W.; Fendler, K.: Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+. The Journal of Biological Chemistry 289, pp. 13168 - 13176 (2014)
Journal Article
Kühlbrandt, W.: The Resolution Revolution. Science 343 (6178), pp. 1443 - 1444 (2014)
Journal Article
Allegretti, M.; Mills, D. J.; McMullen, G.; Kühlbrandt, W.; Vonck, J.: Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector. eLife 3, e01963 (2014)
Journal Article
Paulino, C.; Kühlbrandt, W.: pH- and sodium-induced changes in a sodium/proton antiporter. eLife 3, e01412 (2014)
Journal Article
Herrmann, J.; Berberich, H.; Hartmann, J.; Beyer, S.; Davies, K.; Koch, J.: Homo-oligomerization of the Activating Natural Killer Cell Receptor NKp30 Ectodomain Increases Its Binding Affinity for Cellular Ligands. The Journal of Biological Chemistry 289 (2), pp. 765 - 777 (2014)
Journal Article
Daum, B.; Quax, T. E. F.; Sachse, M.; Mills, D. J.; Reimann, J.; Yildiz, Ö.; Häder, S.; Saveanu, C.; Forterre, P.; Albers, S.-V. et al.; Kühlbrandt, W.; Prangishvili, D.: Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proceedings of the National Academy of Sciences of the United States of America 111 (10), pp. 3829 - 3834 (2014)
Journal Article
Davies, K. M.; Daum, B.; Gold, V. A. M.; Mühleip, A. W.; Brandt, T.; Blum, T.; Mills, D. J.; Kühlbrandt, W.: Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography. Journal of Visualized Experiments (91 doi: 10.3791/51228), e51228 (2014)
Journal Article
Imhof, M.; Rhinow, D.; Hampp, N.: Two-photon polarization data storage in bacteriorhodopsin films and its potential use in security applications. Applied Physics Letters 104, 081921 (2014)
Journal Article
Keller, R.; Ziegler, C.; Schneider, D.: When two turn into one: evolution of membrane transporters from half modules. Biological Chemistry 395 (12), pp. 1379 - 1388 (2014)
Journal Article
Köster, S.; van Pee, K.; Hudel, M.; Leustik, M.; Rhinow, D.; Kühlbrandt, W.; Chakraborty, T.: Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation. Nature Communications 5, 3690 (2014)
Journal Article
Matthies, D.; Zhou, W.; Klyszejko, A. L.; Anselmi, C.; Yildiz, Ö.; Brandt, K.; Müller, V.; Faraldo-Gómez, J. D.; Faraldo-Gómez, J. D.; Meier, T.: High-resolution structure and mechanism of an F/V-hybrid rotor ring in a Na+-coupled ATP synthase. Nature Communications 5, 5286 (2014)
Journal Article
Mourier, A.; Ruzzenente, B.; Brandt, T.; Kühlbrandt, W.; Larsson, N.-G.: Loss of LRPPRC causes ATP synthase deficiency. Human Molecular Genetics 23 (10), pp. 2580 - 2592 (2014)
Journal Article
Salzer, R.; Herzberg, M.; Nies, D. H.; Joos, F.; Rathmann, B.; Thielmann, Y.; Averhoff, B.: Zinc and ATP Binding of the Hexameric AAA-ATPase PilF from Thermus thermophilus: ROLE IN COMPLEX STABILITY, PILIATION, ADHESION, TWITCHING MOTILITY, AND NATURAL TRANSFORMATION. The Journal of Biological Chemistry 289 (44), pp. 30343 - 30354 (2014)
Journal Article
Salzer, R.; Joos, F.; Averhoff, B.: Type IV Pilus Biogenesis, Twitching Motility, and DNA Uptake in Thermus thermophilus: Discrete Roles of Antagonistic ATPases PilF, PilT1, and PilT2. Applied and Environmental Microbiology 80 (2), pp. 644 - 652 (2014)
Journal Article
Schweikhard, E. S.; Kempson, S. A.; Ziegler, C.; Burckhardt, B. C.: Mutation of a single threonine in the cytoplasmic NH2 terminus disrupts trafficking of renal betaine-GABA transporter 1 during hypertonic stress. American Journal of Physiology - Renal Physiology 307 (1), pp. F107 - F115 (2014)
Journal Article
Stockburger, C.; Gold, V. A. M.; Pallas, T.; Kolesova, N.; Miano, D.; Leuner, K.: A cell model for the initial phase of sporadic Alzheimer’s disease. Journal of Alzheimer's Disease 42 (2), pp. 395 - 411 (2014)
Journal Article
Zhang, C.; Allegretti, M.; Vonck, J.; Langer, J.; Marcia, M.; Peng, G.; Michel, H.: Production of fully assembled and active Aquifex aeolicus F1FO ATP synthase in Escherichia coli. Biochimica et Biophysica Acta (BBA) - General Subjects 1840 (1), pp. 34 - 40 (2014)

Thesis - PhD (10)

2014
Thesis - PhD
Paulino, C. B.: Structural and functional characterization of the Na+/H+antiporter MjNhap1. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Koshy, C.: Insights into the functional and regulatory mechanisms of the osmoregulated Na+/glycine betaine symporter BetP from Corynebacterium glutamicum: A structural and computational study. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Preiß, L.: Structural and functional characterization of the rotor rings from a Bacillus and a Mycobacterium F-type ATP synthase. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Walter, A.: Development, implementation and practical aspects of phase plates in electron cryo-microscopy. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Kapotova, E.: Three-dimensional crystallization of the sodium-proton antiporter NhaP1 from Methanocaldococcus jannaschii. Dissertation, Goethe university, Frankfurt am Main (2014)
Thesis - PhD
Matthies, D.: Biochemical and structural analysis of F-type ATP synthases and its subcomplexes. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Schweikhard, E. S.: Na+-coupled betaine symporters involved in osmotic stress response in prokaryotes and eukaryotes. Dissertation, Johannes Gutenberg-Universität, Mainz (2014)
Thesis - PhD
Müller, M.: Structure and function of channelrhodopsin-2 by cryo electron crystallography. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Daum, B.: Electron cryo-tomography of bioenergetic membranes. Dissertation, Goethe-Universität, Frankfurt am Main (2014)
Thesis - PhD
Ciccarelli, L.: Mycobacterium tuberculosis type-I fatty acid synthase: Structure and conformational variability of a protein complex by single-particle electron cryo-microscopy. Dissertation, Goethe-Universität, Frankfurt (2014)

Thesis - Habilitation (1)

2014
Thesis - Habilitation
Rhinow, D.: Biological and Artificial Membranes - Structural Analysis and Nanotechnological Applications. Habilitation, Philipps-Universität, Marburg (2014)
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