Werner Kühlbrandt: Structural Biology – Department Publications

Journal Article (21)

2019
Journal Article
Brünle, S.; Eisinger, M. L.; Poppe, J.; Mills, D. J.; Langer, J. D.; Vonck, J.; Ermler, U.: Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism. Proceedings of the National Academy of Sciences of the United States of America 52 (116), pp. 26497 - 26504 (2019)
Journal Article
Parey, K.; Haapanen, O.; Sharma, V.; Köfeler, H.; Züllig, T.; Prinz, S.; Siegmund, K.; Wittig, I.; Mills, D.; Vonck, J. et al.; Kühlbrandt, W.; Zickermann, V.: High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Science Advances 5 (12), p. eaax9484 (2019)
Journal Article
Pfeil-Gardiner, O.; Mills, D. J.; Vonck, J.; Kuehlbrandt, W.: A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling. IUCrJ 6, pp. 1099 - 1105 (2019)
Journal Article
Ruesink, H.; Reimer, L.; Gregersen, E.; Möller, A.; Betzer, C.; Jensen, P. H.: Stabilization of α-synuclein oligomers using formaldehyde. PLoS One 14 (10), e0216764 (2019)
Journal Article
Safarian, S.; Hahn, A.; Mills, D.; Radloff, M.; Eisinger, M. L.; Nikolaev, A.; Meier-Credo, J.; Melin, F.; Miyoshi, H.; Gennis, R.B. et al.; Sakamoto, J.; Langer, J. D.; Hellwig, P.; Kühlbrandt, W.; Michel, H.: Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366 (6461), pp. 100 - 104 (2019)
Journal Article
Hofmann, S.; Januliene, D.; Mehdipour, A. R.; Thomas, C.; Stefan, E.; Brüchert, S.; Kuhn, B. T.; Geertsma, E. R.; Hummer, G.; Tampé, R. et al.; Möller, A.: Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature 571 (7766), pp. 580 - 583 (2019)
Journal Article
Faelber, K.; Dietrich, L.; Noel, J. K.; Wollweber, F.; Pfitzner, A.-K.; Mühleip, A.; Sánchez, R.; Kudryashev, M.; Chiaruttini, N.; Lilie, H. et al.; Schlegel, J.; Rosenbaum, E.; Hessenberger, M.; Matthaeus, C.; Kunz, S.; von der Malsburg, A.; Noè, F.; Roux, A.; van der Laan, M.; Kühlbrandt, W.; Daumke, O.: Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature 571 (7765), pp. 429 - 433 (2019)
Journal Article
Timcenko, M.; Lyons, J. A.; Januliene, D.; Ulstrup, J. J.; Dieudonné, T.; Montigny, C.; Ash, M.-R.; Karlsen, J. L.; Boesen, T.; Kühlbrandt, W. et al.; Lenoir, G.; Möller, A.; Nissen, P.: Structure and autoregulation of a P4-ATPase lipid flippase. Nature 571 (7765), pp. 366 - 370 (2019)
Journal Article
Vögele, M.; Bhaskara, R.; Mulvihill, E.; van Pee, K.; Yildiz, Ö.; Kühlbrandt, W.; Müller, D. J.; Hummer, G.: Membrane perforation by the pore-forming toxin pneumolysin. Proceedings of the National Academy of Sciences of the United States of America 116 (27), pp. 13352 - 13357 (2019)
Journal Article
Bausewein, T.; Nussberger, S.; Kühlbrandt, W.: Cryo-EM structure of Neurospora crassa respiratory complex IV. IUCrJ 6 (4), pp. 773 - 780 (2019)
Journal Article
Scherr, J.; Neuhaus, A.; Parey, K.; Klusch, N.; Murphy, B. J.; Zickermann, V.; Kühlbrandt, W.; Terfort, A.; Rhinow, D.: Noncovalent Functionalization of Carbon Substrates with Hydrogels Improves Structural Analysis of Vitrified Proteins by Electron Cryo-Microscopy. ACS Nano 13 (6), pp. 7185 - 7190 (2019)
Journal Article
Murphy, B. J.; Klusch, N.; Langer, J. D.; Mills, D.; Yildiz, Ö.; Kühlbrandt, W.: Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Science 364 (6446), eaaw9128, p. 1155 (2019)
Journal Article
Yilmaz, I.; Yildiz, Ö.; Korkmaz, F.: Structural properties of an engineered outer membrane protein G mutant, OmpG-16SL, investigated with infrared spectroscopy. Journal of Biomolecular Structure and Dynamics 37 (2019)
Journal Article
Akram, M.; Dietl, A.; Mersdorf, U.; Prinz, S.; Maalcke, W. J.; Keltjens, J. T.; Ferousi, C.; de Almeida, N. M.; Reimann, J.; Kartal, B. et al.; Jetten, M. S. M.; Parey, K.; Barends, T.: A 192-heme electron transfer network in the hydrazine dehydrogenase complex. Science Advances 5 (4), eaav4310 (2019)
Journal Article
Okazaki, K.-i.; Wöhlert, D.; Warnau, J.; Jung, H.; Yildiz, Ö.; Kühlbrandt, W.; Hummer, G.: Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting. Nature Communications 10, 1742 (2019)
Journal Article
D'Imprima, E.; Floris, D.; Joppe, M.; Sánchez, R.; Grinninger, M.; Kühlbrandt, W.: Protein denaturation at the air-water interface and how to prevent it. eLife 8, e42747 (2019)
Journal Article
Reich, S.; Kaiser, P.; Mafi, M.; Schmalz, H.; Rhinow, D.; Freitag, R.; Greiner, A.: High-Temperature Spray-Dried Polymer/Bacteria Microparticles for Electrospinning of Composite Nonwovens. Macromolecular Bioscience 19 (3), 1800356 (2019)
Journal Article
Blum, T.; Hahn, A.; Meier, T.; Davies, K. M.; Kühlbrandt, W.: Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows. Proceedings of the National Academy of Sciences of the United States of America 116 (10), pp. 4250 - 4255 (2019)
Journal Article
Leone, V.; Waclawska, I.; Kossmann, K.; Koshy, C.; Sharma, M.; Prisner, T. F.; Ziegler, C.; Endeward, B.; Forrest, L. R.: Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP. Journal of General Physiology 151 (3), pp. 381 - 394 (2019)
Journal Article
Kühlbrandt, W.: Structure and Mechanisms of F-Type ATP Synthases. Annual Review of Biochemistry 88, pp. 515 - 549 (2019)
Journal Article
Sousa, J. S.; Vonck, J.: Respiratory supercomplexes III2IV2 come into focus. Nature Structural and Molecular Biology 26 (2), pp. 87 - 89 (2019)

Conference Paper (3)

2019
Conference Paper
Lyons, J. A.; Laban, M.; Januliene, D.; Ustrup, J.; Montigny, C.; Dieudonné, T.; Guinot, V.; Kühlbrandt, W.; Lenoir, G.; Möller, A. et al.; Nissen, P.: Structural Insights into the Function and Auto-Regulation of Lipid Flippases. 63rd Annual Meeting of the Biophysical-Society, Baltimore, March 02, 2019 - March 06, 2019. Biophysical Journal (Annual Meeting Abstracts) 116 (3), 170A, (2019)
Conference Paper
Eder, M.; Dordic, A.; Sagmeister, T.; Damisch, E.; Vejzovic, D.; Berni, F.; Codee, J.; Palva, A.; Vonck, J.; Oberer, M. et al.; Pavkov-Keller, T.: Surface layer proteins of lactobacilli – determining the cell wall binding and their antibacterial effect. Acta Crystallographica Section A: Foundations and Advances 75, E196, (2019)
Conference Paper
Hofer, G.; Payer, S. E.; Plasch, K.; Baerland, N.; Marschall, S. A.; Sheng, X.; Vonck, J.; Gruber, K.; Himo, F.; Leys, D. et al.; Faber, K.; Keller, W.; Glueck, S. M.; Pavkov-Keller, T.: Regioselective carboxylation by prenylated flavin and Mn-dependent decarboxylases. Acta Crystallographica Section A: Foundations and Advances 75, E119, (2019)

Thesis - PhD (2)

2019
Thesis - PhD
Sousa, J. S.: Structural characterization of membrane protein complexes by single-particle cryo-EM. Dissertation, 191 pp., Fachbereich 14 (Biochemie, Chemie, Pharmazie), Goethe-Universität Frankfurt, Frankfurt am Main (2019)
Thesis - PhD
Eisel, B.: Inhibition of F1F0 ATP synthases by bacterial virulence factors and photoswitchable azo-polyphenols. Dissertation, 259 pp., Fachbereich 14 (Biochemie, Chemie, Pharmazie), Goethe-Universität Frankfurt, Frankfurt am Main (2019)

Thesis - Master (5)

2019
Thesis - Master
Steinhilper, R.: Structural characterization of the E. coli formate hydrogenlyase complex by cryo electron microscopy. Master, 82 pp., Philipps University of Marburg, Marburg (2019)
Thesis - Master
Liu, J.: CryoEM analysis of the conformational cycle of the bacterial ABC transporter MsbA under turnover conditions. Master, 70 pp., Technische Universität München, München (2019)
Thesis - Master
Ulitzka, M.: Native-like Expression Systems for Receptor-like Kinases of Plants. Master, 60 pp., Technische Universität Darmstadt, Darmstadt (2019)
Thesis - Master
Pfeil-Gardiner, O.: Comparing liquid helium and liquid nitrogen cooling for high-resolution cryo-EM of a test specimen. Master, 43 pp., Fachbereich Physik, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2019)
Thesis - Master
Siebert, J.: Is SorCS1 autoinhibited? Biochemical and biophysical characterization of SorCS1. Master, 73 pp., Goethe-Universität Frankfurt, Frankfurt (2019)
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