Ralf Steinhilper

Ralf Steinhilper

PhD Student
Research group “Bonnie Murphy: Redox and Metalloproteins”

I started my PhD in Bonnie Murphy’s research group in early 2020. Before that, I studied chemistry at the University of Marburg, where I initially came into contact with structural biology techniques. Fascinated by the potential of single-particle cryo-EM, I decided to conduct the research for my master’s thesis in the group of Werner Kühlbrandt at the MPI of Biophysics, where Bonnie was already my primary supervisor.
During my PhD, I focus on the biochemical and structural characterization of group 4-membrane bound hydrogenases (MBHs), which share an evolutionary link to respiratory complex I.

Ralf Steinhilper Publications

Journal Article (2)

Journal Article
Schulz, V.; Steinhilper, R.; Oltmanns, J.; Freibert, S.-A.; Krapoth, N.; Linne, U.; Welsch, S.; Hoock, M. H.; Schünemann, V.; Murphy, B. J. et al.; Lill, R.: Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nature Communications 15, 3269 (2024)
Journal Article
Steinhilper, R.; Höff, G.; Heider, J.; Murphy, B. J.: Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli. Nature Communications 13, 5395 (2022)

Thesis - Master (1)

Thesis - Master
Steinhilper, R.: Structural characterization of the E. coli formate hydrogenlyase complex by cryo electron microscopy. Master, 82 pp., Philipps University of Marburg, Marburg (2019)
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