Publications of the Emeritus Department of Biophysical Chemistry

Search results

Journal Article (25)

2015
Journal Article
Fowler, P. W.; Orwick-Rydmark, M.; Radestock, S.; Solcan, N.; Dijkman, P. M.; Lyons, J. A.; Kwok, J.; Caffrey, M.; Watts, A.; Forrest, L. R. et al.; Newstead, S.: Gating Topology of the Proton-Coupled Oligopeptide Symporters. Structure 23 (2), pp. 290 - 301 (2015)
Journal Article
Schweikhard, E. S.; Burckhardt, B. C.; Joos, F.; Fenollar-Ferrer, C.; Forrest, L. R.; Kempson, S. A.; Ziegler, C.: Role of N-glycosylation in renal betaine transport. Biochemical Journal 470 (2), pp. 169 - 179 (2015)
2014
Journal Article
Fenollar-Ferrer, C.; Stockner, T.; Schwarz, T. C.; Pal, A.; Gotovina, J.; Hofmaier, T.; Jayaraman, K.; Adhikary, S.; Kudlacek, O.; Mehdipour, A. R. et al.; Tavoulari, S.; Rudnick, G.; Singh, S. K.; Konrat, R.; Sitte, H. H.; Forrest, L. R.: Structure and Regulatory Interactions of the Cytoplasmic Terminal Domains of Serotonin Transporter. Biochemistry 53 (33), pp. 5444 - 5460 (2014)
Journal Article
Perez, C.; Faust, B.; Mehdipour, A. R.; Francesconi, K. A.; Forrest, L. R.; Ziegler, C.: Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling. Nature Communications 5, 4231 (2014)
Journal Article
Stamm, M.; Staritzbichler, R.; Khafizov, K.; Forrest, L. R.: AlignMe-a membrane protein sequence alignment web server. Nucleic Acids Research 42 (W1), pp. W246 - W251 (2014)
Journal Article
Fenollar-Ferrer, C.; Patti, M.; Knöpfel, T.; Werner, A.; Forster, I. C.; Forrest, L. R.: Structural Fold and Binding Sites of the Human Na+-Phosphate Cotransporter NaPi-II. Biophysical Journal 106 (6), pp. 1268 - 1279 (2014)
2013
Journal Article
Yaffe, D.; Radestock, S.; Shuster, Y.; Forrest, L. R.; Schuldiner, S.: Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the USA 110 (15), pp. E1332 - E1341 (2013)
Journal Article
Stamm, M.; Staritzbichler, R.; Khafizov, K.; Forrest, L. R.: Alignment of Helical Membrane Protein Sequences Using AlignMe. PLoS ONE 8 (3), p. e57731 - e57731 (2013)
Journal Article
Forrest, L. R.: (Pseudo-)Symmetrical Transport. Science 339 (6118), pp. 339 - 401 (2013)
Journal Article
Silverstein, N.; Crisman, T. J.; Forrest, L. R.; Kanner, B. I.: Cysteine Scanning Mutagenesis of Transmembrane Helix 3 of a Brain Glutamate Transporter Reveals Two Conformationally Sensitive Positions. The Journal of Biological Chemistry 288 (2), pp. 964 - 973 (2013)
2012
Journal Article
Gradogna, A.; Fenollar-Ferrer, C.; Forrest, L. R.; Pusch, M.: Dissecting a regulatory calcium-binding site of CLC-K kidney chloride channels. The Journal of General Physiology 140 (6), pp. 681 - 696 (2012)
Journal Article
Schushan, M.; Rimon, A.; Haliloglu, T.; Forrest, L. R.; Padan, E.; Ben-Tal, N.: A Model-Structure of a Periplasm-facing State of the NhaA Antiporter Suggests the Molecular Underpinnings of pH-induced Conformational Changes. The Journal of Biological Chemistry 287 (22), pp. 18249 - 18261 (2012)
Journal Article
Khafizov, K.; Perez, C.; Koshy, C.; Quick, M.; Fendler, K.; Ziegler, C.; Forrest, L. R.: Investigation of the sodium binding sites in the betaine transporter BetP. Proceedings of the National Academy of Sciences of the Untited States of America 109 (44), pp. 17754 - 17755 (2012)
2011
Journal Article
Radestock, S.; Forrest, L. R.: The Alternating-Access Mechanism of MFS Transporters Arises from Inverted-Topology Repeats. Journal of Molecular Biology 407 (5), pp. 698 - 715 (2011)
Journal Article
Staritzbichler, R.; Anselmi, C.; Forrest, L. R.; Faraldo-Gómez, J. D.: GRIFFIN: A Versatile Methodology for Optimization of Protein-Lipid Interfaces for Membrane Protein Simulations. Journal of Chemical Theory and Computation 7 (4), pp. 1167 - 1176 (2011)
Journal Article
Faraldo-Gómez, J. D.; Forrest, L. R.: Modeling and simulation of ion-coupled and ATP-driven membrane proteins. Current Opinion in Structural Biology 21 (2), pp. 173 - 179 (2011)
Journal Article
Forrest, L. R.; Krämer, R.; Ziegler, C.: The structural basis of secondary active transport mechanisms. Biochimica et Biophysica Acta - Bioenergetics 1807 (2), pp. 167 - 188 (2011)
Journal Article
Tavoulari, S.; Rizwan, A. N.; Forrest, L. R.; Rudnick, G.: Reconstructing a Chloride-binding Site in a Bacterial Neurotransmitter Transporter Homologue. The Journal of Biological Chemistry 286 (4), pp. 2834 - 2842 (2011)
Journal Article
Perez, C.; Khafizov, K.; Forrest, L. R.; Krämer, R.; Ziegler, C.: The role of trimerization in the osmoregulated betaine transporter BetP. EMBO Reports 12 (8), pp. 804 - 810 (2011)
Journal Article
Tsai, C.-J.; Khafizov, K.; Hakulinen, J.; Forrest, L. R.; Krämer, R.; Kühlbrandt, W.; Ziegler, C.: Structural Asymmetry in a Trimeric Na+/Betaine Symporter, BetP, from Corynebacterium glutamicum. Journal of Molecular Biology 407 (3), pp. 368 - 381 (2011)
2010
Journal Article
Khafizov, K.; Staritzbichler, R.; Stamm, M.; Forrest, L. R.: A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe. Biochemistry 49 (50), pp. 10702 - 10713 (2010)
2009
Journal Article
Crisman, T. J.; Qu, S.; Kanner, B. I.; Forrest, L. R.: Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats. Proceedings of the National Academy of Sciences of the United States of America 106 (49), pp. 20752 - 20757 (2009)
Journal Article
Forrest, L. R.; Rudnick, G.: The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters. Physiology 24 (6), pp. 377 - 386 (2009)
Journal Article
Tavoulari, S.; Forrest, L. R.; Rudnick, G.: Fluoxetine (Prozac) Binding to Serotonin Transporter Is Modulated by Chloride and Conformational Changes. The Journal of Neuroscience 29 (30), pp. 9635 - 9643 (2009)
2008
Journal Article
Trötschel, C.; Follmann, M.; Nettekoven, J. A.; Mohrbach, T.; Forrest, L. R.; Burkovski, A.; Marin, K.; Krämer, R.: Methionine Uptake in Corynebacterium glutamicum by MetQNI and by MetPS, a Novel Methionine and Alanine Importer of the NSS Neurotransmitter Transporter Family. Biochemistry 47 (48), pp. 12698 - 12709 (2008)

Conference Paper (1)

2011
Conference Paper
Khafizov, K.; Perez, C.; Tsai, C.-J.; Ziegler, C.; Forrest, L. R.: Computational and Experimental Studies of Substrate Binding, Conformational Change and Importance of the Trimeric State in the Glycine Betaine Transporter BetP. Biophysical Journal 100 (3, Supplement 1), p. 132a - 132a (2011)
Go to Editor View