Publications of Florian Wilfling

Journal Article (24)

2022
Journal Article
Schmitt, D.; Bozkurt, S.; Henning-Domres, P.; Huesmann, H.; Eimer, S.; Bindila, L.; Behrends, C.; Boyle, E.; Wilfling, F.; Tascher, G. et al.; Münch, C.; Behl, C.; Kern, A.: FACS-mediated isolation of native autophagic vesicles. Autophagy (2022)
Journal Article
Schmitt, D.; Bozkurt, S.; Henning-Domres, P.; Huesmann, H.; Eimer, S.; Bindila, L.; Behrends, C.; Boyle, E.; Wilfling, F.; Tascher, G. et al.; Münch, C.; Behl, C.; Kern, A.: Lipid and protein content profiling of isolated native autophagic vesicles. EMBO Reports, e53065 (2022)
Journal Article
Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B. A.; Baumeister, W. et al.; Wilfling, F.: In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39), e2209823119 (2022)
Journal Article
Enenkel, C.; Kang, R. W.; Wilfling, F.; Ernst, O. P.: Intracellular localization of the proteasome in response to stress conditions. The Journal of Biological Chemistry 298 (7), 102083 (2022)
Journal Article
Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Vu, D. T.; von Gronau, S. et al.; Mann, M.; Wilfling, F.; Schulman, B. A.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13, 3041 (2022)
Journal Article
Boyle, E.; Wilfling, F.: Bypassing the nuclear gate: A non-canonical entry pathway for the mitochondrial pyruvate dehydrogenase complex. Molecular Cell 82 (5), pp. 886 - 888 (2022)
2021
Journal Article
Bieber, A.; Capitanio, C.; Wilfling, F.; Plitzko, J.; Erdmann, P. S.: Sample Preparation by 3D-Correlative Focused Ion Beam Milling for High-Resolution Cryo-Electron Tomography. Journal of Visualized Experiments (176), e62886 (2021)
Journal Article
Wilfling, F.; Lee, C.-W.; Erdmann, P. S.; Baumeister, W.: Autophagy ENDing unproductive phase-separated endocytic protein deposits. Autophagy 17 (10), pp. 3264 - 3265 (2021)
Journal Article
Erdbrügger, P.; Wilfling, F.: p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 118 (37), e2113647118 (2021)
Journal Article
Erdmann, P. S.; Hou, Z.; Klumpe, S.; Khavnekar, S.; Beck, F.; Wilfling, F.; Plitzko, J. M.; Baumeister, W.: In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications 12 (1), 5364 (2021)
2020
Journal Article
Wilfling, F.; Lee, C.-W.; Erdmann, P. S.; Zheng, Y.; Sherpa, D.; Jentsch, S.; Pfander, B.; Schulman, B. A.; Baumeister, W.: A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits. Molecular Cell 80 (5), pp. 764 - 778 (2020)
Journal Article
Allegretti, M.; Zimmerli, C. E.; Rantos, V.; Wilfling, F.; Ronchi, P.; Fung, H. K. H.; Lee, C.-W.; Hagen, W.; Turoňová, B.; Karius, K. et al.; Börmel, M.; Zhang, X.; Müller, C. W.; Schwab, Y.; Mahamid, J.; Pfander, B.; Kosinski, J.; Beck, M.: In-cell architecture of the nuclear pore and snapshots of its turnover. Nature 586 (7831), pp. 796 - 800 (2020)
Journal Article
Bittmann, J.; Grigaitis, R.; Galanti, L.; Amarell, S.; Wilfling, F.; Matos, J.; Pfander, B.: An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases. eLife 9, e52459 (2020)
Journal Article
Lee, C.-W.; Wilfling, F.; Ronchi, P.; Allegretti, M.; Mosalaganti, S.; Jentsch, S.; Beck, M.; Pfander, B.: Selective autophagy degrades nuclear pore complexes. Nature Cell Biology 22 (2), pp. 159 - 166 (2020)
2015
Journal Article
Frank, D. O.; Dengjel, J.; Wilfling, F.; Kozjak-Pavlovic, V.; Häcker, G.; Weber, A.: The Pro-Apoptotic BH3-Only Protein Bim Interacts with Components of the Translocase of the Outer Mitochondrial Membrane (TOM). PLoS One 10 (4), e0123341 (2015)
2014
Journal Article
Wilfling, F.; Haas, J. T.; Walther, T. C.; Farese, R. V.: Lipid droplet biogenesis. Current Opinion in Cell Biology 29, pp. 39 - 45 (2014)
Journal Article
Wilfling, F.; Thiam, A. R.; Olarte, M.-J.; Wang, J.; Beck, R.; Gould, T. J.; Allgeyer, E. S.; Pincet, F.; Bewersdorf, J.; Farese, R. V. et al.; Walther, T. C.: Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting. eLife 3, e01607 (2014)
2013
Journal Article
Thiam, A. R.; Antonny, B.; Wang, J.; Delacotte, J.; Wilfling, F.; Walther, T. C.; Beck, R.; Rothman, J. E.; Pincet, F.: COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. Proceedings of the National Academy of Sciences of the United States of America 110 (33), pp. 13244 - 13249 (2013)
Journal Article
Mejhert, N.; Wilfling, F.; Esteve, D.; Galitzky, J.; Pellegrinelli, V.; Kolditz, C.-I.; Viguerie, N.; Tordjman, J.; Näslund, E.; Trayhurn, P. et al.; Lacasa, D.; Dahlman, I.; Stich, V.; Lång, P.; Langin, D.; Bouloumié, A.; Clément, K.; Rydén, M.: Semaphorin 3C is a novel adipokine linked to extracellular matrix composition. Diabetologia 56 (8), pp. 1792 - 1801 (2013)
Journal Article
Krahmer, N.; Hilger, M.; Kory, N.; Wilfling, F.; Stoehr, G.; Mann, M.; Farese Jr., R. V.; Walther, T. C.: Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence. Molecular and Cellular Proteomics 12 (5), pp. 1115 - 1126 (2013)
Journal Article
Wilfling, F.; Wang, H.; Haas, J. T.; Krahmer, N.; Gould, T. J.; Uchida, A.; Cheng, J.-X.; Graham, M.; Christiano, R.; Fröhlich, F. et al.; Liu, X.; Buhman, K. K.; Coleman, R. A.; Bewersdorf, J.; Farese, R. V.; Walther, T. C.: Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Developmental Cell 24 (4), pp. 384 - 399 (2013)
2012
Journal Article
Wilfling, F.; Weber, A.; Potthoff, S.; Vögtle, F.-N.; Meisinger, C.; Paschen, S. A.; Häcker, G.: BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax. Cell Death and Differentiation 19 (8), pp. 1328 - 1336 (2012)
2011
Journal Article
Krahmer, N.; Guo, Y.; Wilfling, F.; Hilger, M.; Lingrell, S.; Heger, K.; Newman, H. W.; Schmidt-Supprian, M.; Vance, D. E.; Mann, M. et al.; Farese, R. V.; Walther, T. C.: Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metabolism 14 (4), pp. 504 - 515 (2011)
2007
Journal Article
Weber, A.; Paschen, S. A.; Heger, K.; Wilfling, F.; Frankenberg, T.; Bauerschmitt, H.; Seiffert, B. M.; Kirschnek, S.; Wagner, H.; Häcker, G.: Bims-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins. The Journal of Cell Biology: JCB 177 (4), pp. 625 - 636 (2007)
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