Max Planck Institute of Biophysics

Ernst Bamberg Publications

2025

Journal Article

Zabelskii, D.; Bukhdruker, S.; Bukhalovich, S.; Tsybrov, F.; Lamm, G. H. U.; Astashkin, R.; Doroginin, D.; Matveev, G.; Sudarev, V.; Kuzmin, A. et al.; Zinovev, E.; Vlasova, A.; Ryzhykau, Y.; Ilyinsky, N.; Gushchin, I.; Bourenkov, G.; Alekseev, A.; Round, A.; Wachtveitl, J.; Bamberg, E.; Gordeliy, V.: Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nature Structural & Molecular Biology 32 (8), pp. 1347 - 1357 (2025)

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Journal Article

Bukhdruker, S.; Gushchin, I.; Shevchenko, V.; Kovalev, K.; Polovinkin, V.; Tsybrov, F.; Astashkin, R.; Alekseev, A.; Mikhaylov, A.; Bukhalovich, S. et al.; Bratanov, D.; Ryzhykau, Y.; Kuklina, D.; Caramello, N.; Rokitskaya, T.; Antonenko, Y.; Rulev, M.; Stoev, C.; Zabelskii, D.; Round, E.; Rogachev, A.; Borshchevskiy, V.; Ghai, R.; Bourenkov, G.; Zeghouf, M.; Cherfils, J.; Engelhard, M.; Chizhov, I.; Rodriguez-Valera, F.; Bamberg, E.; Gordeliy, V.: Proteorhodopsin insights into the molecular mechanism of vectorial proton transport. Science Advances 11 (16), eadu5303 (2025)

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2024

Journal Article

Asido, M.; Boumrifak, C.; Weissbecker, J.; Bamberg, E.; Wachtveitl, J.: Vibrational Study of the Inward Proton Pump Xenorhodopsin NsXeR: Switch Order Determines Vectoriality. Journal of Molecular Biology 436 (5), 168447 (2024)

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Journal Article

Vlasova, A. D.; Bukhalovich, S. M.; Bagaeva, D. F.; Polyakova, A. P.; Ilyinsky, N. S.; Nesterov, S. V.; Tsybrov, F. M.; Bogorodskiy, A. O.; Zinovev, E. V.; Mikhailov, A. E. et al.; Vlasov, A. V.; Kuklin, A. I.; Borshchevskiy, V. I.; Bamberg, E.; Uversky, V. N.; Gordeliy, V. I.: Intracellular microbial rhodopsin-based optogenetics to control metabolism and cell signaling. Chemical Society Reviews 53 (7), pp. 3327 - 3349 (2024)

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Journal Article

Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A. A.; Fedou, S.; Thézé, N.; Zabelskii, D.; Alekseev, A.; Bamberg, E.; Gordeliy, V.; Sandoz, G. et al.; Vivaudou, M.: Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins. Nature Communications 15 (1), 65 (2024)

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2023

Journal Article

Bühl, E.; Resler, T.; Lam, R. S.; Asido, M.; Bamberg, E.; Schlesinger, R.; Bamann, C.; Heberle, J.; Wachtveitl, J.: Assessing the Role of R120 in the Gating of Cr ChR2 by Time-Resolved Spectroscopy from Femtoseconds to Seconds. Journal of the American Chemical Society 145 (40), pp. 21832 - 21840 (2023)

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Journal Article

Gorriti, M. F.; Bamann, C.; Alonso-Reyes, D. G.; Wood, P. G.; Bamberg, E.; Farías, M. E.; Gärtner, W.; Albarracín, V. H.: Functional characterization of xanthorhodopsin in Salinivibrio socompensis, a novel halophile isolated from modern stromatolites. Photochemical & Photobiological Sciences 22 (8), pp. 1809 - 1823 (2023)

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Journal Article

Kovalev, K.; Tsybrov, F.; Alekseev, A.; Shevchenko, V.; Soloviov, D.; Siletsky, S.; Bourenkov, G.; Agthe, M.; Nikolova, M.; von Stetten, D. et al.; Astashkin, R.; Bukhdruker, S.; Chizhov, I.; Royant, A.; Kuzmin, A.; Gushchin, I.; Rosselli, R.; Rodriguez-Valera, F.; Ilyinskiy, N.; Rogachev, A.; Borshchevskiy, V.; Schneider, T. R.; Bamberg, E.; Gordeliy, V.: Mechanisms of inward transmembrane proton translocation. Nature Structural and Molecular Biology 30 (7), pp. 970 - 979 (2023)

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Journal Article

Okhrimenko, I. S.; Kovalev, K.; Petrovskaya, L. E.; Ilyinsky, N. S.; Alekseev, A. A.; Marin, E.; Rokitskaya, T. I.; Antonenko, Y. N.; Siletsky, S. A.; Popov, P. A. et al.; Zagryadskaya, Y. A.; Soloviov, D. V.; Chizhov, I. V.; Zabelskii, D. V.; Ryzhykau, Y. L.; Vlasov, A. V.; Kuklin, A. I.; Bogorodskiy, A. O.; Mikhailov, A. E.; Sidorov, D. V.; Bukhalovich, S.; Tsybrov, F.; Bukhdruker, S.; Vlasova, A. D.; Borshchevskiy, V. I.; Dolgikh, D. A.; Kirpichnikov, M. P.; Bamberg, E.; Gordeliy, V. I.: Mirror proteorhodopsins. Communications Chemistry 6, 88 (2023)

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2022

Journal Article

Astashkin, R.; Kovalev, K.; Bukhdruker, S.; Vaganova, S.; Kuzmin, A.; Alekseev, A.; Balandin, T.; Zabelskii, D.; Gushchin, I.; Royant, A. et al.; Volkov, D.; Bourenkov, G.; Koonin, E.; Engelhard, M.; Bamberg, E.; Gordeliy, V.: Structural insights into light-driven anion pumping in cyanobacteria. Nature Communications 13, 6460 (2022)

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Journal Article

Borshchevskiy, V.; Kovalev, K.; Round, E.; Efremov, R.; Astashkin, R.; Bourenkov, G.; Bratanov, D.; Balandin, T.; Chizhov, I.; Baeken, C. et al.; Gushchin, I.; Kuzmin, A.; Alekseev, A.; Rogachev, A.; Willbold, D.; Engelhard, M.; Bamberg, E.; Büldt, G.; Gordeliy, V.: True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nature Structural and Molecular Biology 29 (5), pp. 440 - 450 (2022)

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Book Chapter

Alekseev, A.; Gordeliy, V.; Bamberg, E.: Rhodopsin-Based Optogenetics: Basics and Applications. In: Rhodopsin: Methods and Protocols, pp. 71 - 100 (Ed. Gordeliy, V.). Springer, New York (2022)

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Book Chapter

Gordeliy, V.; Kovalev, K.; Bamberg, E.; Rodriguez-Valera, F.; Zinovev, E.; Zabelskii, D.; Alekseev, A.; Rosselli, R.; Gushchin, I.; Okhrimenko, I.: Microbial Rhodopsins. In: Rhodopsin: Methods and Protocols, pp. 1 - 52 (Ed. Gordeliy, V.). Springer, New York (2022)

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2021

Journal Article

Weissbecker, J.; Boumrifak, C.; Breyer, M.; Wießalla, T.; Shevchenko, V.; Mager, T.; Slavov, C.; Alekseev , A.; Kovalev, K.; Gordeliy , V. et al.; Bamberg, E.; Wachtveitl, J.: The voltage dependent sidedness of the reprotonation of the retinal Schiff base determines the unique inward pumping of Xenorhodopsin. Angewandte Chemie, International Edition in English 60 (42), pp. 23010 - 23017 (2021)

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Journal Article

Zabelskii, D.; Dmitrieva, N.; Volkov, O.; Shevchenko, V.; Kovalev, K.; Balandin, T.; Soloviov, D.; Astashkin, R.; Zinovev, E.; Alekseev, A. et al.; Round, E.; Polovinkin, V.; Chizhov, I.; Rogachev, A.; Okhrimenko, I.; Borshchevskiy, V.; Chupin, V.; Büldt, G.; Yutin, N.; Bamberg, E.; Koonin, E.; Gordeliy, V.: Structure-based insights into evolution of rhodopsins. Communications Biology 4 (1), 821 (2021)

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2020

Journal Article

Zabelskii, D.; Alekseev, A.; Kovalev, K.; Rankovic, V.; Balandin, T.; Soloviov, D.; Bratanov, D.; Savelyeva, E.; Podolyak, E.; Volkov, D. et al.; Vaganova, S.; Astashkin, R.; Chizhov, I.; Yutin, N.; Rulev, M.; Popov, A.; Eria-Oliveira, A.-S.; Rokitskaya, T.; Mager, T.; Antonenko, Y.; Rosselli, R.; Armeev, G.; Shaitan, K.; Vivaudou, M.; Büldt, G.; Rogachev, A.; Rodriguez-Valera, F.; Kirpichnikov, M.; Moser, T.; Offenhäusser, A.; Willbold, D.; Koonin, E.; Bamberg, E.; Gordeliy, V.: Viral rhodopsins 1 are an unique family of light-gated cation channels. Nature Communications 11, 5707 (2020)

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Journal Article

Reyer, A.; Häßler, M.; Scherzer, S.; Huang, S.; Pedersen, J. T.; Al-Rascheid, K. A. S.; Bamberg, E.; Palmgren, M.; Dreyer, I.; Nagel, G. et al.; Hedrich, R.; Becker, D.: Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps. Proceedings of the National Academy of Sciences of the United States of America 117 (34), pp. 20920 - 20925 (2020)

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Journal Article

Kovalev, K.; Astashkin, R.; Gushchin, I.; Orekhov, P.; Volkov, D.; Zinovev, E.; Marin, E.; Rulev, M.; Alekseev, A.; Royant, A. et al.; Carpentier, P.; Vaganova, S.; Zabelskii, D.; Baeken, C.; Sergeev, I.; Balandin, T.; Bourenkov, G.; Carpena, X.; Boer, R.; Maliar, N.; Borshchevskiy, V.; Büldt, G.; Bamberg, E.; Gordeliy, V.: Molecular mechanism of light-driven sodium pumping. Nature Communications 11, 2137 (2020)

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Journal Article

Kovalev, K.; Volkov, D.; Astashkin, R.; Alekseev, A.; Gushchin, I.; Haro-Moreno, J. M.; Chizhov, I.; Siletsky, S.; Mamedov, M.; Rogachev, A. et al.; Balandin, T.; Borshchevskiy, V.; Popov, A.; Bourenkov, G.; Bamberg, E.; Rodriguez-Valera, F.; Büldt, G.; Gordeliy, V.: High-resolution structural insights into the heliorhodopsin family. Proceedings of the National Academy of Sciences of the United States of America 117 (8), pp. 4131 - 4141 (2020)

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2019

Journal Article

Bratanov, D.; Kovalev, K.; Machtens, J.-P.; Astashkin, R.; Chizhov, I.; Soloviov, D.; Volkov, D.; Polovinkin, V.; Zabelskii, D.; Mager, T. et al.; Gushchin, I.; Rokitskaya, T.; Antonenko, Y.; Alekseev, A.; Shevchenko, V.; Yutin, N.; Rosselli, R.; Baeken, C.; Borshchevskiy, V.; Bourenkov, G.; Popov, A.; Balandin, T.; Büldt, G.; Manstein, D. J.; Rodriguez-Valera, F.; Fahlke, C.; Bamberg, E.; Koonin, E.; Gordeliy, V.: Unique structure and function of viral rhodopsins. Nature Communications 10, 4939 (2019)

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Journal Article

Kovalev, K.; Polovinkin, V.; Gushchin, I.; Alekseev, A.; Shevchenko, V.; Borshchevskiy, V.; Astashkin, R.; Balandin, T.; Bratanov, D.; Vaganova, S. et al.; Popov, A.; Chupin, V.; Büldt, G.; Bamberg, E.; Gordeliy, V.: Structure and mechanisms of sodium-pumping KR2 rhodopsin. Science Advances 5, eaav2671 (2019)

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2018

Editorial

Bamberg, E.; Gärtner, W.; Trauner, D.: Introduction: Optogenetics and Photopharmacology. Chemical Reviews 118 (21), pp. 10627 - 10628 (2018)

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Conference Paper

Heberle, J.; Lorenz-Fonfria, V.; Resler, T.; Schultz, B.; Schlesinger, R.; Bamann, C.; Bamberg, E.: Molecular mechanism of channelrhodopsin. 20th European Bioenergetics Conference , Budapest, Hungary, August 25, 2018 - August 30, 2018. Biochimica et Biophysica Acta, Bioenergetics 1859, e27, (2018)

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Journal Article

Mager, T. M.-H.; Lopez de la Morena, D.; Senn, V.; Schlotte, J.; D´Errico, A.; Feldbauer, K.; Wrobel, C.; Jung, S.; Bodensiek, K.; Rankovic, V. et al.; Browne, L.; Huet, A.; Jüttner, J.; Wood, P. G.; Letzkus, J.; Moser, T.; Bamberg, E.: High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. Nature Communications 9, 1750 (2018)

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2017

Journal Article

Volkov, O.; Kovalev, K.; Polovinkin, V.; Borshchevskiy, V.; Bamann, C.; Astashkin, R.; Marin, E.; Popov, A.; Balandin, T.; Willbold, D. et al.; Büldt, G.; Bamberg, E.; Gordeliy, V.: Structural insights into ion conduction by channelrhodopsin 2. Science 358 (6366), eaan8862, p. 1018 (2017)

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Journal Article

Chaffiol, A.; Caplette, R.; Jaillard, C.; Brazhnikova, E.; Desrosiers, M.; Dubus, E.; Duhamel, L.; Macé, E.; Marre, O.; Benoit, P. et al.; Hantraye, P.; Bemelmans, A.-P.; Bamberg, E.; Duebel, J.; Sahel, J.-A.; Picaud, S.; Dalkara, D.: A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina. Molecular Therapy 25 (11), pp. 2546 - 2560 (2017)

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Journal Article

Klapper, S. D.; Sauter, E. J.; Swiersy, A.; Hyman, M. A.E.; Bamann, C.; Bamberg, E.; Busskamp, V.: On-demand optogenetic activation of human stem-cell-derived neurons. Scientific Reports 7, 14450 (2017)

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Journal Article

Shevchenko, V.; Mager, T.; Kovalev, K.; Polovinkin, V.; Alekseev, A.; Juettner, J.; Chizhov, I.; Bamann, C.; Vavourakis, C.; Ghai, R. et al.; Gushchin, I.; Borshchevskiy, V.; Rogachev, A.; Melnikov, I.; Popov, A.; Balandin, T.; Rodriguez-Valera, F.; Manstein, D. J.; Bueldt, G.; Bamberg, E.; Gordeliy, V.: Inward H⁺ pump xenorhodopsin: Mechanism and alternative optogenetic approach. Science Advances 3 (9), e1603187 (2017)

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Journal Article

Mager, T.; Wood, P. G.; Bamberg, E.: Optogenetic Control of Ca²⁺ and Voltage-Dependent Large Conductance (BK) Potassium Channels. Journal of Molecular Biology (London) 429 (6), pp. 911 - 921 (2017)

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Journal Article

Lam, R. S.; Töpfer, F.; Wood, P. G.; Busskamp, V.; Bamberg, E.: Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures. PLoS One 12 (1), e0169506 (2017)

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2016

Journal Article

Feldbauer, K.; Schlegel, J.; Weissbecker, J.; Sauer, F.; Wood, P. G.; Bamberg, E.; Terpitz, U.: Optochemokine tandem for light-control of intracellular Ca²⁺. PLoS One 10 (11), e0165344 (2016)

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Journal Article

Klapper, S. D.; Swiersy, A.; Bamberg, E.; Busskamp, V.: Biophysical Properties of Optogenetic Tools and Their Application for Vision Restoration Approaches. Frontiers in Systems Neuroscience 10, 74 (2016)

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Journal Article

Albarracin, V. H.; Kraiselburd, I.; Bamann, C.; Wood, P. G.; Bamberg, E.; Farias, M. E.; Gärtner, W.: Functional Green-Tuned Proteorhodopsin from Modern Stromatolites. PLoS One 11 (5), e0154962 (2016)

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Journal Article

Gushchin, I.; Shevchenko, V.; Polovinkin, V.; Borshchevskiy, V.; Buslaev, P.; Bamberg, E.; Gordeliy, V.: Structure of the light-driven sodium pump KR2 and its implications for optogenetics. The FEBS Journal 283 (7), pp. 1232 - 1238 (2016)

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2015

Journal Article

Lórenz-Fonfria, V. A.; Bamann, C.; Resler, T.; Schlesinger, R.; Bamberg, E.; Heberle, J.: Temporal evolution of helix hydration in a light-gated ion channel correlates with ion conductance. Proceedings of the National Academy of Sciences of the United States of America 112 (43), pp. E5796 - E5804 (2015)

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Journal Article

Adamantidis, A.; Arber, S.; Bains, J. S.; Bamberg, E.; Bonci, A.; Buzsáki , G.; Cardin , J. A.; Costa, R. M.; Dan, Y.; Goda , Y. et al.; Graybiel, A. M.; Häusser, M.; Hegemann, P.; Huguenard, J. R.; Insel, T. R.; Janak, P. H.; Johnston, D.; Josselyn, S. A.; Koch, C.; Kreitzer, A. C.; Lüscher, C.; Malenka, R. C.; Miesenböck, G.; Nagel, G.; Roska, B.; Schnitzer, M. J.; Shenoy, K. V.; Soltesz , I.; Sternson, S. M.; Tsien , R. W.; Tsien, R. Y.; Turrigiano, G. G.; Tye, K. M.; Wilson, R. I.: Optogenetics: 10 years after ChR2 in neurons—views from the community. Nature Neuroscience 18 (9), pp. 1202 - 1212 (2015)

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Journal Article

Becker-Baldus, J.; Bamann, C.; Saxena, K.; Gustman, H.; Brown, L. J.; Brown, R. C.D.; Reiter, C.; Bamberg, E.; Wachtveitl, J.; Schwalbe, H. et al.; Glaubitz, C.: Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America 112 (32), pp. 9896 - 9901 (2015)

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Journal Article

Gushchin, I.; Shevchenko, V.; Polovinkin, V.; Kovalev, K.; Alekseev, A.; Round, E.; Borshchevskiy, V.; Balandin, T.; Popov, A.; Gensch, T. et al.; Fahlke, C.; Bamann, C.; Willbold, D.; Büldt, G.; Bamberg, E.; Gordeliy, V.: Crystal structure of a light-driven sodium pump. Nature Structural and Molecular Biology 22 (5), pp. 390 - 395 (2015)

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Journal Article

Lórenz-Fonfría, V. A.; Schultz, B.-J.; Resler, T.; Schlesinger, R.; Bamann, C.; Bamberg, E.; Heberle, J.: Pre-Gating Conformational Changes in the ChETA Variant of Channelrhodopsin‑2 Monitored by Nanosecond IR Spectroscopy. Journal of the American Chemical Society 137 (5), pp. 1850 - 1861 (2015)

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Journal Article

Bamberg, E.: Licht steuert Nervenzellen mit höchster Präzision: die Optogenetik revolutioniert die Neurowissenschaften. Forschung Frankfurt: Wissenschaftsmagazin der Goethe-Universität 33 (2), pp. 42 - 45 (2015)

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Journal Article

Macé, E.; Caplette, R.; Marre, O.; Sengupta, A.; Chaffiol, A.; Barbe, P.; Desrosiers, M.; Bamberg, E.; Sahel, J.-A.; Picaud, S. et al.; Duebel, J.; Dalkara, D.: Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice. Molecular Therapy 23 (1), pp. 7 - 16 (2015)

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Journal Article

Müller, M.; Bamann, C.; Bamberg, E.; Kühlbrandt, W.: Light-Induced Helix Movements in Channelrhodopsin-2. J. Mol. Biol. 427 (2), pp. 341 - 349 (2015)

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2014

Journal Article

Bamann, C.; Bamberg, E.; Wachtveitl, J.; Glaubitz, C.: Proteorhodopsin. Biochimica et Biophysica Acta, Bioenergetics 1837 (5), pp. 614 - 625 (2014)

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Journal Article

Hernandez, V. H.; Gehrt, A.; Reuter, K.; Jing, Z.; Jeschke, M.; Mendoza Schulz, A.; Hoch, G.; Bartels, M.; Vogt, G.; Garnham, C. W. et al.; Yawo, H.; Fukazawa, Y.; Augustine, G. J.; Bamberg, E.; Kügler, S.; Salditt, T.; de Hoz, L.; Strenzke, N.; Moser, T.: Optogenetic stimulation of the auditory pathway. The Journal of Clinical Investigation 124 (3), pp. 1114 - 1129 (2014)

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2013

Journal Article

Sattig, T.; Rickert, C.; Bamberg, E.; Steinhoff, H.-J.; Bamann, C.: Light-Induced Movement of the Transmembrane Helix B in Channelrhodopsin-2. Angewandte Chemie, International Edition in English 52 (37), pp. 9705 - 9708 (2013)

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Journal Article

Geibel, S.; Lörinczi, E.; Bamberg, E.; Friedrich, T.: Voltage Dependence of Proton Pumping by Bacteriorhodopsin Mutants with Altered Lifetime of the M Intermediate. PLoS One 8 (9), p. e73338 - e73338 (2013)

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Journal Article

Derrer, C.; Wittek, A.; Bamberg, E.; Carpaneto, A.; Dreyer, I.; Geiger, D.: Conformational Changes Represent the Rate-Limiting Step in the Transport Cycle of Maize SUCROSE TRANSPORTER1. The Plant Cell 25 (8), pp. 3010 - 3021 (2013)

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Journal Article

Neumann-Verhoefen, M.-K.; Neumann, K.; Bamann, C.; Radu, I.; Heberle, J.; Bamberg, E.; Wachtveitl, J.: Ultrafast Infrared Spectroscopy on Channelrhodopsin‑2 Reveals Efficient Energy Transfer from the Retinal Chromophore to the Protein. Journal of the American Chemical Society 135 (18), pp. 6968 - 6976 (2013)

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Journal Article

Janke, C.; Scholz, F.; Becker-Baldus, J.; Glaubitz, C.; Wood, P. G.; Bamberg, E.; Wachtveitl, J.; Bamann, C.: Photocycle and Vectorial Proton Transfer in a Rhodopsin from the Eukaryote Oxyrrhis marina. Biochemistry 52 (16), pp. 2750 - 2763 (2013)

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Journal Article

Lórenz-Fonfría, V. A.; Resler, T.; Krause, N.; Nack, M.; Gossing, M.; Fischer von Mollard, G.; Bamann, C.; Bamberg, E.; Schlesinger, R.; Heberle, J.: Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating. Proceedings of the National Academy of Sciences of the United States of America 110 (14), pp. E1273 - E1281 (2013)

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2012

Journal Article

Terpitz, U.; Letschert, S.; Bonda, U.; Spahn, C.; Guan, C.; Sauer, M.; Zimmermann, U.; Bamberg, E.; Zimmermann, D.; Sukhorukov, . L.: Dielectric Analysis and Multi-cell Electrofusion of the Yeast Pichia pastoris for Electrophysiological Studies. Journal of Membrane Biology 245 (12), pp. 815 - 826 (2012)

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Journal Article

Scholz, F.; Bamberg, E.; Bamann, C.; Wachtveitl, J.: Tuning the Primary Reaction of Channelrhodopsin-2 by Imidazole, pH, and Site-Specific Mutations. Biophysical Journal (Annual Meeting Abstracts) 102 (11), pp. 2649 - 2657 (2012)

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Journal Article

Nack, M.; Radu, I.; Schultz, B.-J.; Resler, T.; Schlesinger, R.; Bondar, A.-N.; del Val, C.; Abbruzzetti, S.; Viappiani, C.; Bamann, C. et al.; Bamberg, E.; Heberle, J.: Kinetics of proton release and uptake by channelrhodopsin-2. FEBS Letters 586 (9), pp. 1344 - 1348 (2012)

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2011

Journal Article

Kleinlogel, S.; Terpitz, U.; Legrum, B.; Gökbuget, D.; Boyden, E. S.; Bamann, C.; Wood, P. G.; Bamberg, E.: A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins. Nature Methods 8 (12), pp. 1083 - 1088 (2011)

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Journal Article

Müller, M.; Bamann, C.; Bamberg, E.; Kühlbrandt, W.: Projection Structure of Channelrhodopsin-2 at 6 Å Resolution by Electron Crystallography. Journal of Molecular Biology 414 (1), pp. 86 - 95 (2011)

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Journal Article

Ruffert, K.; Himmel, B.; Lall, D.; Bamann, C.; Bamberg, E.; Betz, H.; Eulenburg, V.: Glutamate residue 90 in the predicted transmembrane domain 2 is crucial for cation flux through channelrhodopsin 2. Biochemical and Biophysical Research Communications 410 (4), pp. 737 - 743 (2011)

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Journal Article

Hänsel, R.; Löhr, F.; Foldynová-Trantírková, S.; Bamberg, E.; Trantírek, L.; Dötsch, V.: The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions. Nucleic Acids Research 39 (13), pp. 5768 - 5775 (2011)

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Journal Article

Schultheis, C.; Liewald, J. F.; Bamberg, E.; Nagel, G.; Gottschalk, A.: Optogenetic Long-Term Manipulation of Behavior and Animal Development. PLoS ONE 6 (4), e18766 (2011)

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Journal Article

Kleinlogel, S.; Feldbauer, K.; Dempski, R. E.; Fotis, H.; Wood, P. G.; Bamann, C.; Bamberg, E.: Ultra light-sensitive and fast neuronal activation with the Ca²⁺-permeable channelrhodopsin CatCh. Nature Neuroscience 14 (4), pp. 513 - 518 (2011)

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Journal Article

Yonehara, K.; Balint, K.; Noda, M.; Nagel, G.; Bamberg, E.; Roska, B.: Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature 469 (7330), pp. 407 - 410 (2011)

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2010

Journal Article

Verhoefen, M.-K.; Bamann, C.; Blöcher, R.; Förster, U.; Bamberg, E.; Wachtveitl, J.: The Photocycle of Channelrhodopsin-2: Ultrafast Reaction Dynamics and Subsequent Reaction Steps. ChemPhysChem 11 (14), pp. 3113 - 3122 (2010)

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Journal Article

Bamann, C.; Nagel, G.; Bamberg, E.: Microbial rhodopsins in the spotlight. Current Opinion in Neurobiology 20 (5), pp. 610 - 616 (2010)

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Journal Article

Hofmann, B.; Maybeck, V.; Eick, S.; Meffert, S.; Ingebrandt, S.; Wood, P.; Bamberg, E.; Offenhäusser, A.: Light induced stimulation and delay of cardiac activity. Lab on a Chip 10 (19), pp. 2588 - 2596 (2010)

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Journal Article

Carpaneto, A.; Koepsell, H.; Bamberg, E.; Hedrich, R.; Geiger, D.: Sucrose- and H⁺-Dependent Charge Movements Associated with the Gating of Sucrose Transporter ZmSUT1. PLoS One 5 (9), e12605 (2010)

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Journal Article

Zimmermann, U.; Rüger, S.; Shapira, O.; Westhoff, M.; Wegner, L.H.; Reuss, R.; Gessner, P.; Zimmermann, G.; Israeli, Y.; Zhou, A. et al.; Schwartz, A.; Bamberg, E.; Zimmermann, D.: Effects of environmental parameters and irrigation on the turgor pressure of banana plants measured using the non-invasive, online monitoring leaf patch clamp pressure probe. Plant Biology 12 (3), pp. 424 - 436 (2010)

MPG.PuRe

Journal Article

Hoffmann, J.; Aslimovska, L.; Bamann, C.; Glaubitz, C.; Bamberg, E.; Brutschy, B.: Studying the stoichiometries of membrane proteins by mass spectrometry: microbial rhodopsins and a potassium ion channel. Physical Chemistry Chemical Physics 12 (14), pp. 3480 - 3485 (2010)

MPG.PuRe

Journal Article

Nack, M.; Radu, I.; Gossing, M.; Bamann, C.; Bamberg, E.; Fischer von Mollard, G.; Heberle, J.: The DC gate in Channelrhodopsin-2: crucial hydrogen bonding interaction between C128 and D156. Photochemical & Photobiological Sciences 9 (2), pp. 194 - 198 (2010)

MPG.PuRe

Journal Article

Bamann, C.; Gueta, R.; Kleinlogel, S.; Nagel, G.; Bamberg, E.: Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond. Biochemistry 49 (2), pp. 267 - 278 (2010)

MPG.PuRe

2009

Journal Article

Nack, M.; Radu, I.; Bamann, C.; Bamberg, E.; Heberle, J.: The retinal structure of channelrhodopsin-2 assessed by resonance Raman spectroscopy. FEBS Letters 583 (22), pp. 3676 - 3680 (2009)

MPG.PuRe

Journal Article

Hänsel, R.; Foldynová-Trantírková, S.; Löhr, F.; Buck, J.; Bongartz, E.; Bamberg, E.; Schwalbe, H.; Dötsch, V.; Trantírek, L.: Evaluation of Parameters Critical for Observing Nucleic Acids Inside Living Xenopus laevis Oocytes by In-Cell NMR Spectroscopy. Journal of the American Chemical Society 131 (43), pp. 15761 - 15768 (2009)

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Journal Article

Lörinczi, E.; Verhoefen, M.-K.; Wachtveitl, J.; Woerner; Glaubitz, C.; Engelhard, M.; Bamberg, E.; Friedrich, T.: Voltage- and pH-Dependent Changes in Vectoriality of Photocurrents Mediated by Wild-type and Mutant Proteorhodopsins upon Expression in Xenopus Oocytes. Journal of Molecular Biology 393 (2), pp. 320 - 341 (2009)

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Journal Article

Westhoff, M.; Reuss, R.; Zimmermann, D.; Netzer, Y.; Gessner, A.; Geßner, P.; Zimmermann, G.; Wegner, L. H.; Bamberg, E.; Schwartz, A. et al.; Zimmermann, U.: A non-invasive probe for online-monitoring of turgor pressure changes under field conditions. Plant Biology 11 (5), pp. 701 - 712 (2009)

MPG.PuRe

Journal Article

Feldbauer, K.; Zimmermann, D.; Pintschovius, V.; Spitz, J.; Bamann, C.; Bamberg, E.: Channelrhodopsin-2 is a leaky proton pump. Proceedings of the National Academy of Sciences of the United States of America 106 (30), pp. 12317 - 12322 (2009)

MPG.PuRe

Journal Article

Geys, S.; Bamberg, E.; Dempski, R. E.: Ligand-Dependent Effects on the Conformational Equilibrium of the Na⁺,K⁺-ATPase As Monitored by Voltage Clamp Fluorometry. Biophysical Journal 96 (11), pp. 4561 - 4570 (2009)

MPG.PuRe

Journal Article

Radu, I.; Bamann, C.; Nack, M.; Nagel, G.; Bamberg, E.; Heberle, J.: Conformational Changes of Channelrhodopsin-2. Journal of the American Chemical Society 131 (21), pp. 7313 - 7319 (2009)

MPG.PuRe

Journal Article

Dempski, R. E.; Friedrich, T.; Bamberg, E.: Voltage clamp fluorometry: Combining fluorescence and electrophysiological methods to examine the structure–function of the Na⁺/K⁺-ATPase. Biochimica et Biophysica Acta, Bioenergetics 1787 (6), pp. 714 - 720 (2009)

MPG.PuRe

Journal Article

Westhoff, M.; Zimmermann, D.; Schneider, H.; Wegner, L. H.; Geßner, P.; Jakob, P.; Bamberg, E.; Shirley, S.; Bentrup, F.-W.; Zimmermann, U.: Evidence for discontinuous water columns in the xylem conduit of tall birch trees. Plant Biology 11 (3), pp. 307 - 327 (2009)

MPG.PuRe

Journal Article

Tavraz, N. N.; Dürr, K. L.; Koenderink, J. B.; Freilinger, T.; Bamberg, E.; Dichgans, M.; Friedrich, T.: Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine. Channels 3 (2), pp. 82 - 87 (2009)

MPG.PuRe

Journal Article

Dürr, K. L.; Tavraz, N. N.; Dempski, R. E.; Bamberg, E.; Friedrich, T.: Functional Significance of E₂ State Stabilization by Specific α/β-Subunit Interactions of Na,K- and H,K-ATPase. The Journal of Biological Chemistry 284 (6), pp. 3842 - 3854 (2009)

MPG.PuRe

2008

Journal Article

Tavraz, N. N.; Friedrich, T.; Dürr, K. L.; Koenderink, J. B.; Bamberg, E.; Freilinger, T.; Dichgans, M.: Diverse functional consequences of mutations in the Na⁺/K⁺-ATPase alpha₂-subunit causing familial hemiplegic migraine type 2. The Journal of Biological Chemistry 283 (45), pp. 31097 - 31106 (2008)

MPG.PuRe

Journal Article

Cladwell, J. H.; Herin, G. A.; Nagel, G.; Bamberg, E.; Scheschonka, A.; Betz, H.: Increases in Intracellular Calcium Triggered by Channelrhodopsin-2 Potentiate the Response of Metabotropic Glutamate Receptor mGluR7. The Journal of Biological Chemistry 283 (36), pp. 24300 - 24307 (2008)

MPG.PuRe

Journal Article

Westhoff, M.; Schneider, H.; Zimmermann, D.; Mimietz, S.; Stinzing, A.; Wegner, L. H.; Kaiser, W.; Krohne, G.; Shirley, S.; Bamberg, E. et al.; Bentrup, F.-W.; Zimmermann, U.: The mechanisms of refilling of xylem conduits and bleeding of tall birch during spring. Plant Biology 10 (5), pp. 604 - 623 (2008)

MPG.PuRe

Journal Article

Zimmermann, D.; Reuss, R.; Westhoff, M.; Geßner, P.; Bamberg, E.; Bentrup, F.-W.; Zimmermann, U.: A novel, non-invasive, online-monitoring, versatile and easy plant-based probe for measuring leaf water status. Journal of Experimental Botany 59 (11), pp. 3157 - 3167 (2008)

MPG.PuRe

Journal Article

Terpitz, U.; Raimunda, D.; Westhoff, M.; Sukhorukov, V. L.; Beaugé, L.; Bamberg, E.; Zimmermann, D.: Electrofused giant protoplasts of Saccharomyces cerevisiae as a novel system for electrophysiological studies on membrane proteins. Biochimica et Biophysica Acta: BBA 1778 (6), pp. 1493 - 1500 (2008)

MPG.PuRe

Journal Article

Krieger, F.; Mourot, A.; Araoz, R.; Kotzyba-Hibert, F.; Molgó , J.; Bamberg, E.; Goeldner, M.: Fluorescent agonists for the torpedo nicotinic acetylcholine receptor. ChemBioChem: A European Journal of Chemical Biology 9 (7), pp. 1146 - 1153 (2008)

MPG.PuRe

Journal Article

Zimmermann, D.; Zhou, A.; Kiesel, M.; Feldbauer, K.; Terpitz, U.; Haase, W.; Schneider-Hohendorf, T.; Bamberg, E.; Sukhorukov, V. L.: Effects on capacitance by overexpression of membrane proteins. Biochemical and Biophysical Research Communications 369 (4), pp. 1022 - 1026 (2008)

MPG.PuRe

Journal Article

Dürr, K. L.; Tavraz, N. N.; Zimmermann, D.; Bamberg, E.; Friedrich, T.: Characterization of Na,K-ATPase and H,K-ATPase Enzymes with Glycosylation-Deficient β-Subunit Voltage-Clamp Fluorometry in Xenopus Oocytes. Biochemistry 47 (14), pp. 4288 - 4297 (2008)

MPG.PuRe

Journal Article

Lörinczi, E.; Tsivkoskii, R.; Haase, W.; Bamberg, E.; Lutsenko, S.; Friedrich, T.: Delivery of the Cu-transporting ATPase ATP7B to the plasma membrane in Xenopus oocytes. Biochimica et Biophysica Acta: BBA 1778 (4), pp. 896 - 906 (2008)

MPG.PuRe

Journal Article

Mourot, A.; Bamberg, E.; Rettinger, J.: Agonist- and competitive antagonist-induced movement of loop 5 on the α subunit of the neuronal α4β4 nicotinic acetylcholine receptor. Journal of Neurochemistry 105 (2), pp. 413 - 424 (2008)

MPG.PuRe

Journal Article

Bamann, C.; Kirsch, T.; Nagel, G.; Bamberg, E.: Spectral Characteristics of the Photocycle of Channelrhodopsin-2 and Its Implication for Channel Function. Journal of Molecular Biology (London) 375 (3), pp. 686 - 694 (2008)

MPG.PuRe

Journal Article

Dempski, R. E.; Lustig, J.; Friedrich, T.; Bamberg, E.: Structural Arrangement and Conformational Dynamics of the γ Subunit of the Na⁺/K⁺-ATPase. Biochemistry 47 (1), pp. 257 - 266 (2008)

MPG.PuRe

Journal Article

Gorbunov, D.; Gorboulev, V.; Shatskaya, N.; Mueller, T.; Bamberg, E.; Friedrich, T.; Koepsell, H.: High-affinity Cation Binding to Organic Cation Transporter OCT1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modeled Interaction Domain between Two Helices. Molecular Pharmacology 73 (1), pp. 50 - 61 (2008)

MPG.PuRe

Journal Article

Zimmermann, D.; Kiesel, M.; Terpitz, U.; Zhou, A.; Reuss, R.; Kraus, J.; Schenk, W. A.; Bamberg, E.; Sukhorukov, V. L.: A Combined Patch-Clamp and Electrorotation Study of the Voltage- and Frequency-Dependent Membrane Capacitance Caused by Structurally Dissimilar Lipophilic Anions. Journal of Membrane Biology 221 (2), pp. 107 - 121 (2008)

MPG.PuRe

2007

Journal Article

Zimmermann, D.; Westhoff, M.; Zimmermann, G.; Geßner, P.; Wegner, L.H.; Rokitta, M.; Ache, P.; Schneider, H.; Vásquez, J.A.; Kruck, W. et al.; Shirley, S.; Jakob, P.; Hedrich, R.; Bentrup, F.-W.; Bamberg, E.; Zimmermann, U.: Foliar water supply of tall trees: evidence for mucilage-facilitated moisture uptake from the atmosphere and the impact on pressure bomb measurements. Protoplasma 232 (1-2), 11, pp. 11 - 34 (2007)

MPG.PuRe

Journal Article

Sukhorukov, V. L.; Endter, J. M.; Zimmermann, D.; Shirakashi, R.; Fehrmann, S.; Kiesel, M.; Reuss, R.; Hedrich, R.; Bamberg, E.; Roitsch, T. G. et al.; Zimmermann, U.: Mechanisms of electrically mediated cytosolic Ca²⁺ transients in aequorin-transformed tobacco cells. Biophysical Journal 93 (9), pp. 3324 - 3337 (2007)

MPG.PuRe

Journal Article

Haase, A.; Wood, P. G.; Pintschovius, V.; Bamberg, E.; Hartung, K.: Time resolved kinetics of the guinea pig Na-Ca exchanger (NCX1) expressed in Xenopus oocytes: voltage and Ca²⁺ dependence of the pre-steady-state current investigated by photolytic Ca²⁺ concentration jumps. Pflügers Archiv: European Journal of Physiology 454 (6), pp. 1031 - 1042 (2007)

MPG.PuRe

Journal Article

Kalmbach, R.; Chizhov, I.; Schuhmacher, M. C.; Friedrich, T.; Bamberg, E.; Engelhard, M.: Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes. Journal of Molecular Biology 371 (3), pp. 639 - 648 (2007)

MPG.PuRe

Journal Article

Zhang, F.; Wang, L.-P.; Brauner, M.; Liewald, J. F.; Kay, K.; Watzke, N.; Wood, P. G.; Bamberg, E.; Nagel, G.; Gottschalk, A. et al.; Deisseroth, K.: Multimodal fast optical interrogation of neural circuitry. Nature 446 (7136), pp. 633 - 639 (2007)

MPG.PuRe

Conference Paper

Terpitz, U.; Raimunda, D.; Zhou, A.; Feldbauer, K.; Sukhorukov, V.; Beauge, L.; Bamberg, E.; Zimmermann, D.: Giant cells obtained by electrofusion: a novel heterologeous expression system. 6th EBSA European Biophysics Congress, Imperial College London, July 14, 2007 - July 18, 2007. European Biophysics Journal 36 (Supplement 1), p. S152 - S152 (2007)

MPG.PuRe