Publications of Ulrike Demmer

Fuchs, J.; Fernández-Arévalo, U.; Demmer, U.; Díaz, E.; Ullmann, G. M.; Pierik, A. J.; Ermler, U.; Boll, M.: Enzymatic Birch reduction via hydrogen atom transfer at [4Fe-4S]-OH₂ and [8Fe-9S] clusters. Nature Communications 16, 3236 (2025)

Joshi, T.; Demmer, U.; Schneider, C.; Glaser, T.; Warkentin, E.; Ermler, U.; Mack, M.: The phosphatase RosC from Streptomyces davaonensis is used for roseoflavin biosynthesis and has evolved to largely prevent dephosphorylation of the important cofactor riboflavin-5'-phosphate. Journal of Molecular Biology 436 (20), 168734 (2024)

Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Mutational and structural studies of (βα)₈-barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism. Protein Science 33 (6), e5018 (2024)

Demmer, U.; Lemaire, O.; Belhamri, M.; Ermler, U.: Ethoxylate Polymer-Based 96-Well Screen for Protein Crystallization. Crystals 13, 1519 (2023)

Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Crystal structure of FAD-independent methylene-tetrahydrofolate reductase from Mycobacterium hassiacum. Proteins: Structure, Function, and Bioinformatics 91 (9), pp. 1329 - 1340 (2023)

Weidenweber, S.; Schühle, K.; Lippert, M.-L.; Mock, J.; Seubert, A.; Demmer, U.; Ermler, U.; Heider, J.: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyses the final step of anaerobic toluene metabolism. The FEBS Journal 5, 166 (2022)

Kung, J.; Meier, A.-K.; Willistein, M.; Weidenweber, S.; Demmer, U.; Ermler, U.; Boll, M.: Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem 22 (22), pp. 3172 - 3177 (2021)

Ernst, C.; Kayastha, K.; Koch , T.; Venceslau, S. S.; Pereira, I. A.C.; Demmer, U.; Ermler, U.; Dahl, C.: Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal 288 (5), pp. 1664 - 1678 (2021)

Huang, G.; Wagner, T.; Demmer, U.; Warkentin, E.; Ermler, U.; Shima, S.: The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. Journal of Molecular Biology (London) 432 (7), pp. 2042 - 2054 (2020)

Willistein, M.; Bechtel, D. F.; Müller, C. S.; Demmer, U.; Heimann, L.; Kayastha, K.; Schünemann, V.; Pierik, A. J.; Ullmann, G. M.; Ermler, U. et al.; Boll, M.: Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactorsLow potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors. Nature Communications 10, 2074 (2019)

Brünle, S.; Poppe, J.; Hail, R.; Demmer, U.; Ermler, U.: The molybdenum storage protein - A bionanolab for creating experimentally alterable polyoxomolybdate clusters. Journal of Inorganic Biochemistry 189 (12), pp. 172 - 179 (2018)

Demmer, J. K.; Bertsch, J.; Öppinger, C.; Wohlers, H.; Kayastha, K.; Demmer, U.; Ermler, U.; Müller, V.: Molecular basis of the flavin‐based electron‐bifurcating caffeyl‐CoA reductase reaction. FEBS Letters 592 (3), pp. 332 - 342 (2018)

Warkentin, E.; Weidenweber, S.; Schühle, K.; Demmer, U.; Heider, J.; Ermler, U.: A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins: Structure, Function, and Bioinformatics 85 (11), pp. 2017 - 2023 (2017)

Konjik, V.; Brünle, S.; Demmer, U.; Vanselow, A.; Sandhoff, R.; Ermler, U.; Mack, M.: The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angewandte Chemie, International Edition in English 56 (4), pp. 1146 - 1151 (2017)

Weidenweber, S.; Schühle, K.; Demmer, U.; Warkentin, E.; Ermler, U.; Heider, J.: Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Scientific Reports 7, 39674 (2017)

Demmer, J. K.; Huang, H.; Wang, S.; Demmer, U.; Thauer, R. K.; Ermler, U.: Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure. The Journal of Biological Chemistry 290 (36), pp. 21985 - 21885 (2015)

Poppe, J.; Warkentin, E.; Demmer, U.; Kowalewski, B.; Dierks, T.; Schneider, K.; Ermler, U.: Structural diversity of polyoxomolybdate clusters along the three-fold axis of the molybdenum storage protein. Journal of Inorganic Biochemistry 138, pp. 122 - 128 (2014)

Chowdhury, N. P.; Mowafy, A. M.; Demmer, J. K.; Upadhyay, V.; Koelzer, S.; Jayamani, E.; Kahnt, J.; Hornung, M.; Demmer, U.; Ermler, U. et al.; Buckel, W.: Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans. The Journal of Biological Chemistry 289 (8), pp. 5145 - 5157 (2014)

Rekittke, I.; Olkhova, E.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum. FEBS Letters 587 (24), pp. 3968 - 3972 (2013)

Parey, K.; Demmer, U.; Warkentin, E.; Wynen, A.; Ermler, U.; Dahl, C.: Structural, Biochemical and Genetic Characterization of Dissimilatory ATP Sulfurylase from Allochromatium vinosum. PLoS One 8 (9), p. e74707 - e74707 (2013)

Demmer, U.; Warkentin, E.; Srivastava, A.; Kockelkorn, D.; Pötter, M.; Marx, A.; Fuchs, G.; Ermler, U.: Structural Basis for a Bispecific NADP⁺ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase. The Journal of Biological Chemistry 288 (9), pp. 6363 - 6370 (2013)

El Hammi, E.; Warkentin, E.; Demmer, U.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Active site analysis of yeast flavohemoglobin based on its structure with a small ligand or econazole. The FEBS Journal 279 (24), pp. 4565 - 4575 (2012)

Upadhyay, V.; Demmer, U.; Warkentin, E.; Moll, J.; Shima, S.; Ermler, U.: Structure and Catalytic Mechanism of N⁵,N¹⁰-Methenyltetrahydromethanopterin Cyclohydrolase. Biochemistry 51 (42), pp. 8435 - 8443 (2012)

Kowalewski, B.; Poppe, J.; Demmer, U.; Warkentin, E.; Dierks, T.; Ermler, U.; Schneider, K.: Nature’s Polyoxometalate Chemistry: X-ray Structure of the Mo Storage Protein Loaded with Discrete Polynuclear Mo−O Clusters. The Journal of Physical Chemistry A 134 (23), pp. 9768 - 9774 (2012)

Shima, S.; Krueger, M.; Weinert, T.; Demmer, U.; Kahnt, J.; Thauer, R. K.; Ermler, U.: Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically. Nature 481 (7379), pp. 98 - 101 (2012)

Rather, L. J.; Weinert, T.; Demmer, U.; Bill, E.; Ismail, W.; Fuchs, G.; Ermler, U.: Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB. The Journal of Biological Chemistry 286 (33), pp. 29241 - 29248 (2011)

El Hammi, E.; Warkentin, E.; Demmer, U.; Limam, F.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds. Biochemistry 50 (7), pp. 1255 - 1264 (2011)

Rekittke, I.; Nonaka, T.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus. FEBS Letters 585 (3), pp. 447 - 451 (2011)

Wischgoll, S.; Demmer, U.; Warkentin, E.; Günther, R.; Boll, M.; Ermler, U.: Structural Basis for Promoting and Preventing Decarboxylation in Glutaryl-Coenzyme A Dehydrogenases. Biochemistry 49 (25), pp. 5350 - 5357 (2010)

Ceh, K.; Demmer, U.; Warkentin, E.; Moll, J.; Thauer, R. K.; Shima, S.; Ermler, U.: Structural Basis of the Hydride Transfer Mechanism in F₄₂₀-Dependent Methylenetetrahydromethanopterin Dehydrogenase. Biochemistry 49 (42), pp. 10098 - 10105 (2009)

Schemberg, J.; Schneider, K.; Demmer, U.; Warkentin, E.; Müller, A.; Ermler, U.: Towards Biological Supramolecular Chemistry: A Variety of Pocket-Templated Metal Oxide Cluster Nucleations in the Cavity of a Mo/W-Storage Protein. Angewandte Chemie, International Edition in English 46 (14), pp. 2408 - 2413 (2007)

Scheffel, F.; Warkentin, E.; Hülsmann, A.; Schneider, E.; Ermler, U.: Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius. FEBS Letters 579 (13), pp. 2953 - 2958 (2005)

Acharya, P.; Gornrich, M.; Hagemeier, C.; Vorholt, J. A.; Thauer, R. K.; Ermler, U.: How an Enzyme Binds the C₁ Carrier Tetrahydromethanopterin. Structure of the Tetrahydromethanopterin-Dependent Formaldehyde-Activating Enzyme (Fae) from Methylobacterium extorquens AM1. The Journal of Biological Chemistry 280 (14), pp. 13712 - 13719 (2005)

Ermler, U.; Hagemeier, C. H.; Roth, A.; Demmer, U.; Grabarse, W.; Warkentin, E.; Vorhott, J. A.: Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1. Structure 10 (8), pp. 1127 - 1137 (2002)