Bonnie Murphy Publications

Nomura, S.; San Segundo-Acosta, P.; Protasov, E.; Kaneko, M.; Kahnt, J.; Murphy, B. J.; Shima, S.: Electron flow in hydrogenotrophic methanogens under nickel limitation. Nature 644 (8076), pp. 490 - 496 (2025)

Murphy, B. J.; Kaila, V. R. I.; Roessler, M. M.; Chukhutsina, V.; Fadini, A.; Hanson, S. M.; Maia, F. R. N. C.; Kovalev, K.: Introducing Bonnie Murphy, Ville Kaila, Maxie Roessler, Volha Chukhutsina, Alisia Fadini, Sonya Hanson, Filipe Maia, and Kirill Kovalev. Structure 33 (5), pp. 829 - 835 (2025)

Yin, M. D.; Lemaire, O. N.; Rosas Jiménez, J. G.; Belhamri, M.; Shevchenko, A.; Hummer, G.; Wagner, T.; Murphy, B. J.: Conformational dynamics of a multienzyme complex in anaerobic carbon fixation. Science 387 (6733), pp. 498 - 504 (2025)

Steinhilper, R.; Boß, L.; Freibert, S.-A.; Schulz, V.; Krapoth, N.; Kaltwasser, S.; Lill, R.; Murphy, B. J.: Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex. Nature Communications 15, 10559 (2024)

Pfeil-Gardiner, O.; Rosa, H. V. D.; Riedel, D.; Chen, Y. S.; Lörks, D.; Kükelhan, P.; Linck, M.; Müller, H.; Van Petegem, F.; Murphy, B. J.: Elemental mapping in single-particle reconstructions by reconstructed electron energy-loss analysis. Nature Methods 21, pp. 2299 - 2306 (2024)

Dubach, V. R. A.; San Segundo-Acosta, P.; Murphy, B. J.: Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase. Nature Structural & Molecular Biology 31 (11), pp. 1769 - 1777 (2024)

Schulz, V.; Steinhilper, R.; Oltmanns, J.; Freibert, S.-A.; Krapoth, N.; Linne, U.; Welsch, S.; Hoock, M. H.; Schünemann, V.; Murphy, B. J. et al.; Lill, R.: Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nature Communications 15, 3269 (2024)

Aziz, I.; Kayastha, K.; Kaltwasser, S.; Vonck, J.; Welsch, S.; Murphy, B. J.; Kahnt, J.; Wu, D.; Wagner, T.; Shima, S. et al.; Ermler, U.: Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis. PNAS 121 (14), e2315568121 (2024)

Steinhilper, R.; Höff, G.; Heider, J.; Murphy, B. J.: Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli. Nature Communications 13, 5395 (2022)

Heit, S.; Geurts, M. M. G.; Murphy, B. J.; Corey, R. A.; Mills, D. J.; Kühlbrandt, W.; Bublitz, M.: Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances 7 (46), eabj5255 (2021)

Watanabe, T.; Pfeil-Gardiner, O.; Kahnt, J.; Koch, J.; Shima, S.; Murphy, B. J.: Three-megadalton complex of methanogenic electron-bifurcating and CO₂-fixing enzymes. Science 373 (6559), pp. 1151 - 1156 (2021)

Evans, R. M.; Krahn, N.; Murphy, B. J.; Lee, H.; Armstrong, F. A.; Soll, D.: Selective cysteine-to-selenocysteine changes in a [NiFe]-hydrogenase confirm a special position for catalysis and oxygen tolerance. Proceedings of the National Academy of Sciences of the United States of America 118 (13), e2100921118 (2021)

Scherr, J.; Neuhaus, A.; Parey, K.; Klusch, N.; Murphy, B. J.; Zickermann, V.; Kühlbrandt, W.; Terfort, A.; Rhinow, D.: Noncovalent Functionalization of Carbon Substrates with Hydrogels Improves Structural Analysis of Vitrified Proteins by Electron Cryo-Microscopy. ACS Nano 13 (6), pp. 7185 - 7190 (2019)

Murphy, B. J.; Klusch, N.; Langer, J. D.; Mills, D.; Yildiz, Ö.; Kühlbrandt, W.: Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F₁-F_o coupling. Science 364 (6446), eaaw9128, p. 1155 (2019)

Klusch, N.; Murphy, B. J.; Mills, D.; Yildiy, Ö.; Kühlbrandt, W.: Structural basis of proton translocation and force generation in mitochondrial ATP synthase. eLife 6, e33274 (2017)

Scherr, J.; Parey, K.; Klusch, N.; Murphy, B. J.; Balser, S.; Neuhaus, A.; Zickermann, V.; Kühlbrandt, W.; Terfort, A.; Rhinow, D.: Self-Perforated Hydrogel Nanomembranes Facilitate Structural Analysis of Proteins by Electron Cryo-Microscopy. ACS Nano 11 (6), pp. 6467 - 6473 (2017)

Armstrong, F. A.; Evans, R. M.; Hexter, S. V.; Roessler, M. M.; Murphy, B. J.; Wulff, P.: Guiding Principles of Hydrogenase Catalysis Instigated and Clarified by Protein Film Electrochemistry. Accounts of Chemical Research 49 (5), pp. 884 - 892 (2016)

Kelly, C. A.; Pinske, C.; Murphy, B. J.; Parkin, A.; Armstrong, F.; Palmer, T.; Sargent, F.: Integration of an [FeFe]-hydrogenase Into the Anaerobic Metabolism of Escherichia coli. Biotechnology Reports 8, pp. 94 - 104 (2015)

Murphy, B. J.; Hidalgo, R.; Roessler, M. M.; Evans, R. M.; Ash, P. A.; Myers, W. K.; Vincent, K. A.; Armstrong, F. A.: Discovery of Dark pH-Dependent H(⁺) Migration in a [NiFe]-Hydrogenase and Its Mechanistic Relevance: Mobilizing the Hydrido Ligand of the Ni-C Intermediate. Journal of the American Chemical Society 137 (26), pp. 8484 - 8489 (2015)

Bachmeier, A.; Murphy, B. J.; Armstrong, F. A.: A Multi-Heme Flavoenzyme as a Solar Conversion Catalyst. Journal of the American Chemical Society 136 (37), pp. 12876 - 12879 (2014)

McDowall, J. S.; Murphy, B. J.; Haumann, M.; Palmer, T.; Armstrong, F. A.; Sargent, F.: Bacterial Formate Hydrogenlyase Complex. Proceedings of the National Academy of Sciences of the United States of America 111 (38), pp. E3948 - E3956 (2014)

Murphy, B. J.; Sargent, F.; A. Armstrong, F.: Transforming an oxygen-tolerant [NiFe] uptake hydrogenase into a proficient, reversible hydrogen producer. Energy & Environmental Science 7 (4), pp. 1426 - 1433 (2014)

Evans, R. M.; Parkin, A.; Roessler, M. M.; Murphy, B. J.; Adamson, H.; Lukey, M. J.; Sargent, F.; Volbeda, A.; Fontecilla-Camps, J. C.; Armstrong, F. A.: Principles of Sustained Enzymatic Hydrogen Oxidation in the Presence of Oxygen--The Crucial Influence of High Potential Fe-S Clusters in the Electron Relay of [NiFe]-hydrogenases. Journal of the American Chemical Society 135 (7), pp. 2694 - 2707 (2013)

Lukey, M. J.; Parkin, A.; Roessler, M. M.; Murphy, B. J.; Harmer, J.; Palmer, T.; Sargent, F.; Armstrong, F. A.: How Escherichia Coli Is Equipped to Oxidize Hydrogen Under Different Redox Conditions. The Journal of Biological Chemistry 285 (6), pp. 3928 - 3938 (2010)