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Latest top papers from our institute

Beata Turoňová et al. In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science, 18 August 2020

New findings on SARS-CoV-2 protein shed light on virus’ ability to infect cells.

Beata Turoňová et al. In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science, 18 August 2020

Murphy, B.J., et al. Science 364, eaaw9128.

Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. 

Murphy, B.J., et al. Science 364, eaaw9128.

Faelber, K, et al. (2019). Nature 571, 429-433.

Structure and assembly of the mitochondrial membrane remodeling GTPase Mgm1.

Faelber, K, et al. (2019). Nature 571, 429-433.

Turoňová, B., et al. (2020). Nature Communications 11, 876

Benchmarking tomographic acquisition schemes for high-resolution structural biology

Turoňová, B., et al. (2020). Nature Communications 11876

Hampoelz, B., et al. (2019). Cell 179(3):671-686

Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis.

Hampoelz, B., et al. (2019). Cell 179(3):671-686

Bhaskara, R.M., et al. (2019). Nature Communications 10, 2370

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.

Bhaskara, R.M., et al. (2019). Nature Communications 10, 2370

von Bülow, S., et al. (2019). Proc Natl Acad Sci USA 116, 9843-52

Dynamic cluster formation determines viscosity and diffusion in dense protein solutions.

von Bülow, S., et al. (2019). Proc Natl Acad Sci USA 116, 9843-52

Brünle, S., et al. (2019). Proc Natl Acad Sci USA. 116, 26497-26504 (2019).

Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism.

Brünle, S., et al. (2019). Proc Natl Acad Sci USA. 116, 26497-26504 (2019).

Press Releases

Wired for Efficiency: How methanogenic microbes manage electrons

September 02, 2021

Methanogenic archaea use sophisticated enzyme systems to live in energy-limited anoxic environments. A key mechanism for saving energy is electron bifurcation, a reaction that ‘splits’ the energy of a pair of electrons, making one more strongly ...

Enzyme structure supports microbial growth

July 15, 2021

Scientists at the Max Planck Institutes for Medical Research in Heidelberg, for Marine Microbiology in Bremen and for Biophysics in Frankfurt am Main, as well as the Radboud University in Nijmegen and other partners, have successfully determined the ...

An accurate atomistic description for the role of vital Magnesium in biological processes

April 08, 2021

Magnesium plays an essential role in many vital processes. To correctly describe its mode of action in biological systems by computer simulations, accurate models with atomistic resolution are crucial. Researchers in the group of Nadine Schwierz at ...

Dynamic model of SARS-CoV-2 spike protein reveals potential new vaccine targets

April 01, 2021

A key feature of SARS-CoV-2 is its spike protein, which extends from its surface and enables it to target and infect human cells. Extensive research has resulted in detailed static models of the spike protein, but these models do not capture the ...

Structure of serotonin receptor in presence of lipids resolved

February 23, 2021

Once again, a step has been taken towards clarifying the action of the neurotransmitter serotonin, often referred to as the "happiness hormone", to one of its receptors, 5-HT3AR. An international team of researchers has succeeded now in elucidating ...

New piece of the HIV infection puzzle solved: virus capsid reaches the cell nucleus intactly

February 10, 2021

For the first time, scientists at the Center for Integrative Infectious Diseases Research at the University Hospital Heidelberg, the Heidelberg European Molecular Biology Laboratory and the Max Planck Institute of Biophysics in Frankfurt have ...

Understanding the structure of the virus

January 30, 2021

Since the beginning of the pandemic, scientists worldwide have been working intensely to precisely characterise the novel SARS-CoV2 virus. Only by understanding in detail how the virus is constructed and how it replicates can targets for effective ...

Scientific highlights 2020

December 21, 2020

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