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An accurate atomistic description for the role of vital Magnesium in biological processes

April 08, 2021

Magnesium plays an essential role in many vital processes. To correctly describe its mode of action in biological systems by computer simulations, accurate models with atomistic resolution are crucial. Researchers in the group of Nadine Schwierz at ...

Dynamic model of SARS-CoV-2 spike protein reveals potential new vaccine targets

April 01, 2021

A key feature of SARS-CoV-2 is its spike protein, which extends from its surface and enables it to target and infect human cells. Extensive research has resulted in detailed static models of the spike protein, but these models do not capture the ...

Structure of serotonin receptor in presence of lipids resolved

February 23, 2021

Once again, a step has been taken towards clarifying the action of the neurotransmitter serotonin, often referred to as the "happiness hormone", to one of its receptors, 5-HT3AR. An international team of researchers has succeeded now in elucidating ...

New piece of the HIV infection puzzle solved: virus capsid reaches the cell nucleus intactly

February 10, 2021

For the first time, scientists at the Center for Integrative Infectious Diseases Research at the University Hospital Heidelberg, the Heidelberg European Molecular Biology Laboratory and the Max Planck Institute of Biophysics in Frankfurt have ...

Understanding the structure of the virus

January 30, 2021

Since the beginning of the pandemic, scientists worldwide have been working intensely to precisely characterise the novel SARS-CoV2 virus. Only by understanding in detail how the virus is constructed and how it replicates can targets for effective ...

Scientific highlights 2020

December 21, 2020

Study unravels details of autophagy machinery assembly

September 07, 2020

Researchers from the University of Vienna, the Max Planck Institute for Biology of Ageing in Cologne and the Max Planck Institute of Biophysics in Frankfurt am Main succeeded in the reconstitution of the autophagosome nucleation using recombinant ...

Nuclear pores in their natural context

September 02, 2020

Scientists from the Max Planck Institutes of Biophysics and Biochemistry and the European Molecular Biology Laboratory, led by Boris Pfander, Jan Kosinski und Martin Beck have studied the 3D structure of nuclear pores in budding yeast (Saccharomyces ...

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