Hartmut Michel

2005

Journal Article

Ma, X.; Koepke, J.; Panjikar, S.; Fritzsch, G.; Stöckigt, J.: Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily. The Journal of Biological Chemistry 280 (14), pp. 13576 - 13583 (2005)

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Journal Article

Fufezan, C.; Drepper, F.; Juhnke, H.; Lancaster, C. R. D.; Un, S.; Rutherford, A.W.; Krieger-Liszkay, A.: Herbicide-induced Changes in Charge Recombination and Redox Potential of Q_A in the T4 Mutant of Blastochloris viridis. Biochemistry 44 (15), pp. 5931 - 5939 (2005)

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Journal Article

Barleben, L.; Ma, X.; Koepke, J.; Peng, G.; Michel, H.; Stöckigt, J.: Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Proteins & Proteomics, pp. 89 - 92 (2005)

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Journal Article

Srinivasan, V.; Rajendran, C.; Sousa, F. L.; Melo, A. M.P.; Saraiva, L. M.; Pereira, M. M.; Santana, M.; Teixeira, M.; Michel, H.: Structure at 1.3 Å Resolution of Rhodothermus marinus caa₃ Cytochrome c Domain. Journal of Molecular Biology (London) 345 (5), pp. 1047 - 1057 (2005)

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Ermler, U.: On the mechanism of methyl-coenzyme M reductase. Dalton Transactions 21, pp. 3451 - 3458 (2005)

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Journal Article

Richter, O.-M. H.; Dürr, K. L.; Kannt, A.; Ludwig, B.; Scandurra, F. M.; Giuffrè, A.; Sarti, P.; Hellwig, P.: Probing the access of protons to the K pathway in the Paracoccus denitrificans cytochrome c oxidase. The FEBS Journal 272 (2), pp. 404 - 412 (2005)

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Journal Article

Warkentin, E.; Hagemeier, C.; Shima, S.; Thauer, R. K.; Ermler, U.: The structure of F₄₂₀-dependent methylenetetrahydromethanopterin dehydrogenase: a crystallographic 'superstructure' of the selenomethionine-labelled protein crystal structure. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen), pp. 198 - 202 (2005)

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2004

Journal Article

Unciuleac, M.; Warkentin, E.; Page, C. C.; Boll, M.; Ermler, U.: Structure of Xanthine Oxidase-Related 4-Hydroxybenzoyl-CoA Reductase with an Additional [4Fe-4S] Cluster and an Inverted Electron Flow. Structure 12 (12), pp. 2249 - 2256 (2004)

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Journal Article

Haas, A. H.; Lancaster, C. R. D.: Calculated Coupling of Transmembrane Electron and Proton Transfer in Dihemic Quinol: Fumarate Reductase. Biophysical Journal 87 (6), pp. 4298 - 4315 (2004)

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Journal Article

Lancaster, C. R. D.: Ion pump in the movies. Nature 432, pp. 286 - 287 (2004)

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Journal Article

Palsdottir, H.; Hunte, C.: Lipids in Membrane Protein Structures. Biochimica et Biophysica Acta: BBA 1666 (1-2), pp. 2 - 18 (2004)

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Journal Article

Ma, X.; Koepke, J.; Fritzsch, G.; Diem, R.; Kutchan, T. M.; Michel, H.; Stöckigt, J.: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochimica et Biophysica Acta-Proteins and Proteomics 1702, pp. 121 - 124 (2004)

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Journal Article

Budiman, K.; Kannt, A.; Lyubenova, S.; Richter, O.-M.; Ludwig, B.; Michel, H.; MacMillan, F.: Tyrosine-167: The Origin of the Radical Species Observed in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide in Paracoccus denitrificans. Biochemistry 43 (37), pp. 11709 - 11716 (2004)

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Journal Article

Ma, X.; Koepke, J.; Bayer, A.; Linhard, V.; Fritzsch, G.; Zhang, B.; Michel, H.; Stöckigt, J.: Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochimica et Biophysica Acta-Proteins and Proteomics 1701 (1-2), pp. 129 - 132 (2004)

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Journal Article

Ritter, M.; Palsdottir, H.; Abe, M.; Mäntele, W.; Hunte, C.; Miyoshi, H.; Hellwig, P.: Direct Evidence for the Interaction of Stigmatellin with a Protonated Acidic Group in the bc₁ Complex from Saccharomyces cerevisiae As Monitored by FTIR Difference Spectroscopy and ¹³C Specific Labeling. Biochemistry 43, pp. 8439 - 8446 (2004)

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Journal Article

Cismasiu, V. B.; Denes, S. A.; Reiländer, H.; Michel, H.; Szedlacsek, S. E.: The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase µ. The Journal of Biological Chemistry 279 (26), pp. 26922 - 26931 (2004)

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Journal Article

Maeda, Y.; Kuroki, R.; Haase, W.; Michel, H.; Reiländer, H.: Comparative analysis of high-affinity ligand binding and G protein coupling of the human CXCR1 chemokine receptor and of a CXCR1-G_i2α fusion protein after heterologous production in baculovirus-infected insect cells. European Journal of Biochemistry 271, pp. 1677 - 1689 (2004)

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Journal Article

Olkhova, E.; Hutter, M. C.; Lill, M. A.; Helms, V.; Michel, H.: Dynamic Water Networks in Cytochrome c Oxidase from Paracoccus denitrificans Investigated by Molecular Dynamics Simulations. Biophysical Journal 86 (4), pp. 1873 - 1889 (2004)

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Journal Article

Aufhammer, S. W.; Warkentin, E.; Berk, H.; Shima, S.; Thauer, R. K.; Ermler, U.: Coenzyme binding in F₄₂₀-dependent secondary alcohol dehydrogenase, a member of the bacterial luciferase family. Structure 12 (3), pp. 361 - 370 (2004)

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Journal Article

Unciuleac, M.; Boll, M.; Warkentin, E.; Ermler, U.: Crystallization of 4-hydroxybenzoyl-CoA reductase and the structure of its electron donor ferredoxin. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 60, pp. 388 - 391 (2004)

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Journal Article

Hofman, C.; Aartsma, T. J.; Michel, H.; Köhler, J.: Spectral dynamics in the B800 band of LH2 from Rhodospirillum molischianum: a single-molecule study. New Journal of Physics 6, pp. 1 - 15 (2004)

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Journal Article

Gross, R.; Pisa, R.; Sänger, M.; Lancaster, C. R. D.; Simon, J.: Characterization of the Menaquinone Reduction Site in the Diheme Cytochrome b Membrane Anchor of Wolinella succinogenes NiFe-hydrogenase. Journal of Biological Chemistry 279, pp. 274 - 281 (2004)

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Journal Article

Grünewald, S.; Haase, W.; Molsberger, E.; Michel, H.; Reiländer, H.: Production of the Human D_2S Receptor in the Methylotrophic Yeast P. pastoris. Receptors and Channels 10 (1), pp. 37 - 50 (2004)

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Journal Article

Weiss, M. S.; Mander, G.; Hedderich, R.; Diederichs, K.; Ermler, U.; Warkentin, E.: Protein structure determination by a combination of long wavelength sulphur phasing and radiation damage induced phasing. Acta Crystallographica Section D-Biological Crystallography D60, pp. 686 - 695 (2004)

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2003

Journal Article

Pfeiffer, K.; Gohil, V.; Stuart, R. A.; Hunte, C.; Brandt, U.; Greenberg, M. L.; Schaegger, H.: Cardiolipin stabilizes respiratory chain supercomplexes. Journal of Biological Chemistry 278 (52), pp. 52873 - 52880 (2003)

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Journal Article

Lancaster, C. R. D.: Wolinella succinogenes quinol-fumarate reductase and its comparison to E. coli succinate:quinone reductase. FEBS Letters 555 (1), pp. 21 - 28 (2003)

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Journal Article

Volk, C.; Gorbulev, V.; Budiman, T.; Nagel, G.; Koepsell, H.: Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2. Molecular Pharmacology 64 (5), pp. 1037 - 1047 (2003)

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Journal Article

Koepke, J.; Scharff, E. I.; Luecke, C.; Rueterjans, H.; Fritzsch, G.: Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 Å resolution. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D59 (10), pp. 1744 - 1754 (2003)

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Journal Article

Kessl, J. J.; Lange, B. B.; Merbitz-Zahradnik, T.; Zwicker, K.; Hill, P.; Neunier, B.; Palsdottir, H.; Hunte, C.; Meshnick, S.; Trumpower, B. L.: Molecular basis for atovaquone binding to the cytochrome bc₁ complex. Journal of Biological Chemistry 278, pp. 31312 - 31318 (2003)

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Journal Article

Palsdottir, H.; Lojero, C. G.; Trumpower, B. L.; Hunte, C.: Structure of the yeast cytochrome bc₁ complex with a hydroxyquinone anion Q_o inhibitor bound. Journal of Biological Chemistry 278, pp. 31303 - 31311 (2003)

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Journal Article

Zickermann, V.; Bostina, M.; Hunte, C.; Ruiz, T.; Radermacher, M.; Brandt, U.: Functional implications from an unexpected position of the 49-kDa subunit of NADH:ubiquinone oxidoreductase. The Journal of Biological Chemistry 278 (31), pp. 29072 - 29078 (2003)

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Journal Article

Hunte, C.; Palsdottir, H.; Trumpower, B. L.: Protonmotive pathways and mechanisms in the cytochrome bc₁ complex. FEBS Letters 545 (1), pp. 39 - 46 (2003)

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Journal Article

Grimaldi, S.; Ostermann, T.; Weiden, N.; Mogi, T.; Miyoshi, H.; Ludwig, B.; Michel, H.; Prisner, T. F.; MacMillan, F.: Asymmetric binding of the high-affinity Q_H.- ubisemiquinone in quinol oxidase (bo₃) from Escherichia coli studied by multifrequency electron paramagnetic resonance spectroscopy. Biochemistry 42 (19), pp. 5632 - 5639 (2003)

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Journal Article

Essen, L.-O.; Harrenga, A.; Ostermeier, C.; Michel, H.: 1.3 Å X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D59 (4), pp. 677 - 687 (2003)

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Journal Article

Peng, G.; Fritzsch, G.; Zickermann, V.; Schaegger, H.; Mentele, R.; Lottspeich, F.; Bostina, M.; Radermacher, M.; Huber, R.; Stetter, K. O. et al.; Michel, H.: Isolation, Characterization and Electron Microscopic Single Particle Analysis of the NADH:Ubiquinone Oxidoreductase (Complex I) from the Hyperthermophilic Eubacterium Aquifex aeolicus. Biochemistry 42 (10), pp. 3032 - 3039 (2003)

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Journal Article

Venturi, M.; Hunte, C.: Monoclonal antibodies for the structural analysis of the Na⁺/H⁺ antiporter NhaA from Escherichia coli. Biochimica et Biophysica Acta-Biomembranes 1610 (1), pp. 46 - 50 (2003)

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Journal Article

Hofmann, C.; Ketelaars, M.; Matsushita, M.; Michel, H.; Aartsma, T. J.; Koehler, J.: Single-molecule study of the Electronic Couplings in a Circular Array of Molecules: Light-Harvesting-2-Complex from Rhodospirillum Molischianum. Physical Review Letters 90 (1), 013004 (2003)

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Journal Article

Wendling, M.; Mourik van, F.; Stokkum van, I. H. M.; Salverda, J. M.; Michel, H.; Grondelle van, R.: Low-intensity pump-probe measurements on the B800 band of Rhodospirillum molischianum. Biophysical Journal 84 (1), pp. 440 - 449 (2003)

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2002

Journal Article

Hunte, C.; Solmaz, S.; Lange, C.: Electron transfer between yeast cytochrome bc₁ complex and cytochrome c: a structural analysis. Biochimica et Biophysica Acta, Bioenergetics 1555 (1-3 Special Issue SI), pp. 21 - 28 (2002)

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Journal Article

Lancaster, C. R. D.: A P-type ion pump at work. Nature structural biology 9 (9), pp. 643 - 645 (2002)

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Journal Article

Mamat, B.; Roth, A.; Grimm, C.; Ermler, U.; Tziatzios, C.; Schubert, D.; Thauer, R. K.; Shima, S.: Crystal structures and enzymatic properties of three formyltransferases from archaea: Environmental adaptation and evolutionary relationship. Protein Science 11 (9), pp. 2168 - 2178 (2002)

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Journal Article

Ermler, U.; Hagemeier, C. H.; Roth, A.; Demmer, U.; Grabarse, W.; Warkentin, E.; Vorhott, J. A.: Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1. Structure 10 (8), pp. 1127 - 1137 (2002)

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Journal Article

Hunte, C.; Michel, H.: Crystallisation of membrane proteins mediated by antibody fragments [Review]. Current Opinion in Structural Biology 12 (4), pp. 503 - 508 (2002)

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Journal Article

Hellwig, P.; Pfitzner, U.; Behr, J.; Rost, B.; Pesavento, R. P.; von Donk, W. v.; Gennis, R. B.; Michel, H.; Ludwig, B.; Mäntele, W.: Vibrational modes of tyrosines in cytochrome c oxidase from Paracoccus denitrificans: FTIR and electrochemical studies on Tyr-D₄-labeled and on Tyr280His and Tyr35Phe mutant enzymes. Biochemistry 41 (29), pp. 9116 - 9125 (2002)

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Journal Article

Shima, S.; Warkentin, E.; Thauer, R. K.; Ermler, U.: Structure and function of enzymes involved in the methanogenic pathway utilizing carbon dioxide and molecular hydrogen [Review]. Journal of Bioenergetics and Biomembranes 93 (6), pp. 519 - 530 (2002)

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Journal Article

Lange, C.; Hunte, C.: Crystal structure of the yeast cytochrome bc₁ complex with its bound substrate cytochrome c. Proceedings of the National Academy of Sciences of the United States of America 99 (5), pp. 2800 - 2805 (2002)

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Journal Article

Ruitenberg, M.; Kannt, A.; Bamberg, E.; Fendler, K.; Michel, H.: Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature 417 (6884), pp. 99 - 102 (2002)

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Journal Article

Psylinakis, E.; Fritzsch, G.; Ghanotakis, D. F.: Isolation and crystallization of CP47, a Photosystem II chlorophyll binding protein. Degradation of CP47 upon dissociation from the core complex. Photosynthesis Research 72 (2), pp. 211 - 216 (2002)

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Journal Article

Barquera, B.; Hellwig, P.; Zhou, W.; Morgan, J. E.; Häse, C. C.; Gosink, K. K.; Nilges, M.; Bruesehoff, P. J.; Roth, A.; Lancaster, C. R. D. et al.; Gennis, R. B.: Purification and characterization of the recombinant Na⁺-translocating NADH: quinone oxidoreductase from vibrio cholerae. Biochemistry 41 (11), pp. 3781 - 3789 (2002)

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Journal Article

Fritz, G.; Roth, A.; Schiffer, A.; Buchert, T.; Bourenkov, G.; Bartunik, H. D.; Huber, H.; Stetter, K. O.; Kroneck, P. M. H.; Ermler, U.: Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-Å resolution. Proceedings of the National Academy of Sciences of the United States of America 99 (4), pp. 1836 - 1841 (2002)

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Journal Article

Kröger, A.; Biel, S.; Simon, J.; Gross, R.; Unden, G.; Lancaster, C. R. D.: Fumarate respiration of Wolinella succinogenes: enzymology, energetics and coupling mechanism [Review]. Biochimica et Biophysica Acta, Bioenergetics 1553 (1-2), pp. 23 - 38 (2002)

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Journal Article

Venturi, M.; Seifert, C.; Hunte, C.: High level production of functional antibody Fab fragments in an oxidizing bacterial cytoplasm. Journal of Molecular Biology (London) 315 (1), pp. 1 - 8 (2002)

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Journal Article

Hövelmann, S.; Hoffmann, S. H.; Kühne, R.; ter Laak, T.; Reiländer, H.; Beckers, T.: Impact of aromatic residues within transmembrane helix 6 of the human gonadotropin-releasing hormone receptor upon agonist and antagonist binding. Biochemistry 41 (4), pp. 1129 - 1136 (2002)

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Journal Article

Lancaster, C. R. D.: Wolinella succionegenes quinol:fumarate reductase - 2.2 Å resolution crystal structure and the E-pathway hypothesis of coupled transmembrane proton and electon transfer. Biochimica et Biophysica Acta, Bioenergetics 1565 (2), pp. 215 - 231 (2002)

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Journal Article

Lancaster, C. R. D.: Succinate: quinone oxidoreductases: an overview. Biochimica et Biophysica Acta, Bioenergetics 1553 (1-2), pp. 1 - 6 (2002)

MPG.PuRe

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Journal Article

Lancaster, C. R. D.; Simon, J.: Succinate: quinone oxidoreductases from epsilon-proteobacteria [Review]. Biochimica et Biophysica Acta, Bioenergetics 1553 (1-2), pp. 84 - 101 (2002)

MPG.PuRe

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2001

Journal Article

Lange, C.; Nett, J. H.; Trumpower, B. L.; Hunte, C.: Specific roles of protein-phospholipid interactions in the yeast cytochrome bc₁ complex structure. EMBO Journal 20 (23), pp. 6591 - 6600 (2001)

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Journal Article

Warkentin, E.; Mamat, B.; Sordel-Klippert, M.; Wicke, M.; Thauer, R. K.; Iwata, M.; Iwata, S.; Ermler, U.; Shima, S.: Structures of F₄₂₀H²:NADP⁺ oxidoreductase with and without its substrates bound. The EMBO Journal 20 (23), pp. 6561 - 6569 (2001)

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Journal Article

Ungar, D.; Barth, A.; Haase, W.; Kauntzinger, A.; Lewitzki, E.; Ruiz, T.; Reiländer, H.; Michel, H.: Analysis of a putative voltage-gated prokaryotic potassium channel. European Journal of Biochemistry 268 (20), pp. 5386 - 5396 (2001)

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Journal Article

Bartoschek, S.; Johansson, M.; Geierstanger, B. H.; Okun, j. G.; Lancaster, C. R. D.; Humpfer, E.; Yu, L.; Yu, C.-A.; Griesinger, C.; Brandt, U.: Three molecules of ubiquinone bind specifically to mitochondrial cytochrome bc₁ complex. The Journal of Biological Chemistry 276 (38), pp. 35231 - 35234 (2001)

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Journal Article

Lee, S. Y.; Hunte, C.; Malaney, S.; Robinson, B. H.: The N-terminus of the Qcr7 protein of the cytochrome bc₁ complex in S. cerevisiae may be involved in facilitating stability of the subcomplex with the Qcr8 Protein and Cytochrome b. Archives of Biochemistry and Biophysics 393 (2), pp. 215 - 221 (2001)

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Journal Article

Hunte, C.: Insights from the structure of the yeast cytochrome bc₁ complex: crystallization of membrane proteins with antibody fragments. FEBS Letters 504 (3), pp. 126 - 132 (2001)

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Journal Article

Lancaster, C. R. D.: Succinate:quinone oxidoreductases – what can we learn from Wolinella succinogenes quinol:fumarate reductase. FEBS Letters 504 (3), pp. 133 - 141 (2001)

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Journal Article

Kannt, A.; Ostermann, T.; Müller, H.; Ruitenberg, M.: Zn²⁺ binding to the cytoplasmic side of Paracoccus denitrificans cytochrome c oxidase selectively uncouples electron transfer and proton translocation. FEBS Letters 503 (2-3), pp. 142 - 146 (2001)

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Journal Article

Scharff, E. I.; Koepke, J.; Fritzsch, G.; Lücke, C.; Rüterjahns, H.: Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris. Structure 9 (6), pp. 493 - 502 (2001)

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Journal Article

Zachariae, U.; Lancaster, C. R. D.: Proton uptake associated with the reduction of the primary quinone Q_A influences the binding site of the secondary quinone Q_B in Rhodopseudomonas viridis photosynthetic reaction centers. Biochimica et Biophysica Acta, Bioenergetics 1505 (2-3), pp. 280 - 290 (2001)

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Journal Article

Grabarse, W.; Mahlert, F.; Duin, E. C.; Goubeaud, M.; Shima, S.; Thauer, R. K.; Lamzin, V.; Ermler, U.: On the mechanism of biological methane formation: structural evidence for conformational changes in methyl-coenzyme M reductase upon substrate binding. Journal of Molecular Biology (London) 309 (1), pp. 315 - 330 (2001)

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Padan , E.; Venturi, M.; Gerchman, Y.; Dover, N.: Na⁺/H⁺ antiporters. Biochimica et Biophysica Acta, Bioenergetics 1505 (1), pp. 144 - 157 (2001)

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Journal Article

Kuglstatter, A.; Ermler, U.; Michel, H.; Baciou, L.; Fritzsch, G.: X-ray Structure Analyses of Photosynthetic Reaction Center Variants from Rhodobacter sphaeroides: Structural Changes Induced by Point Mutations at Position L209 Modulate Electron and Proton Transfer. Biochemistry 40 (14), pp. 4253 - 4260 (2001)

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Gerchman, Y.; Rimon, A.; Venturi, M.; Padan, E.: Oligomerization of NhaA, the Na⁺/H⁺ Antiporter of Escherichia coli in the Membrane and Its Functional and Structural Consequences. Biochemistry 40 (11), pp. 3403 - 3412 (2001)

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Lancaster, C. R. D.; Groß, R.; Simon, J.: A third crystal form of Wolinella succinogenes quinol:fumarate reductase reveals domain closure at the site of fumarate reduction. European Journal of Biochemistry 268 (6), pp. 1820 - 1827 (2001)

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Journal Article

Grimaldi, S.; MacMillan, F.; Ostermann, T.; Ludwig, B.; Michel, H.; Prisner, T.: Q_H^*- Ubisemiquinone Radical in the bo₃-Type Ubiquinol Oxidase Studied by Pulsed Electron Paramagnetic Resonance and Hyperfine Sublevel Correlation Spectroscopy. Biochemistry 40 (4), pp. 1037 - 1043 (2001)

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Scharff, E. I.; Lücke, C.; Fritzsch, G.; Koepke, J.; Hartleib, J.; Dierl, S.; Rüterjans, H.: Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris. Acta Crystallographica Section D-Biological Crystallography 57 (1), pp. 148 - 149 (2001)

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Schiller, H.; Molsberger, E.; Janssen , P.; Michel, H.; Reiländer, H.: Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris. Receptors and Channels 7 (6), pp. 453 - 469 (2001)

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2000

Journal Article

Lancaster, C. R. D.; Bibikova, M.; Sabatino, P.; Oesterhelt, D.; Michel, H.: Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described at 2.00-A resolution. The Journal of Biological Chemistry 275 (50), pp. 39364 - 39368 (2000)

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Roth, A.; Fritz, G.; Büchert, T.; Huber, H.; Stetter, K. O.; Ermler, U.; Kroneck, P. M.H.: Crystallization and preliminary X-ray analysis of adenylylsulfate reductase from Archaeoglobus fulgidus. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D56 (12), pp. 1673 - 1675 (2000)

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Lancaster, C. R. D.; Groß, R.; Haas, A.; Ritter, M.; Mäntele, W.; Simon, J.; Kröger, A.: Essential role of Glu-C66 for menaquinol oxidation indicates transmembrane electrochemical potential generation by Wolinella succinogenes fumarate reductase. Proceedings of the National Academy of Sciences of the United States of America 97 (24), pp. 13051 - 13056 (2000)

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Shima, S.; Thauer, R. K.; Ermler, U.; Durchschlag, H.; Tziatzios, .; Schubert, D.: A mutation affecting the dimer/tetramer association equilibrium of formyltransferase from the hyperthermophilic Methanopyrus kandleri in relation to the activity and thermostability of the enzyme. European Journal of Biochemistry 267 (22), pp. 6619 - 6623 (2000)

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Grabarse, W.; Mahlert, F.; Shima , S.; Thauer, R. K.; Ermler, U.: Comparison of three methyl-coenzyme M reductases from phylogenetically distant organisms: unusual amino acid modification, conservation and adaptation. Journal of Molecular Biology (London) 303 (2), pp. 329 - 344 (2000)

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Michel, H.: Allowing gene patents could be an expensive mistake for the US. Nature 407, p. 285 - 285 (2000)

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Nett, J. H.; Hunte, C.; Trumpower, B. L.: Changes to the length of the flexible linker region of the Rieske protein impair the interaction of ubiquinol with the cytochrome bc₁ complex. European Journal of Biochemistry 267 (18), pp. 5777 - 5782 (2000)

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Lancaster, C. R. D.; Kröger, A.: Succinate: quinone oxidoreductases: new insights from X-ray crystal structures. Biochimica et Biophysica Acta, Bioenergetics 1459 (2-3), pp. 422 - 431 (2000)

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Shima, S.; Warkentin, E.; Grabarse, W.; Sordel, M.; Wicke, M.; Thauer, R. K.; Ermler, U.: Structure of coenzyme F₄₂₀ dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea. Journal of Molecular Biology (London) 300 (4), pp. 935 - 950 (2000)

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Hoffmann, S.; ter Laak , T.; Kühne, R.; Reiländer, H.; Beckers, T.: Residues within Transmembrane Helices 2 and 5 of the Human Gonadotropin-Releasing Hormone Receptor Contribute to Agonist and Antagonist Binding. Molecular Endocrinology 14 (7), pp. 1099 - 1115 (2000)

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Hunte, C.; Koepke, J.; Lange, C.; Roßmanith, T.; Michel, H.: Structure at 2.3 Å resolution of the cytochrome bc₁ complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Structure 8 (6), pp. 669 - 684 (2000)

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Pfitzner, U.; Hoffmeier, K.; Harrenga, A.; Kannt, A.; Michel, H.; Bamberg, E.; Ludwig, B.: Tracing the D-Pathway in Reconstituted Site-Directed Mutants of Cytochrome c Oxidase from Paracoccus denitrificans. Biochemistry 39 (23), pp. 6756 - 6762 (2000)

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Rengers, J.-U.; Touchard, G.; Decourt, C.; Deret, S.; Michel, H.; Cogné, M.: Heavy and light chain primary structures control IgG3 nephritogenicity in an experimental model for cryocrystalglobulinemia. Blood 95 (11), pp. 3467 - 3472 (2000)

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Koepke, J.; Ermler, U.; Warkentin, E.; Wenzl, G.; Flecker, P.: Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 å resolution. Structural basis of Janus-faced serine protease inhibitor specificity. Journal of Molecular Biology (London) 298 (3), pp. 477 - 491 (2000)

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Ruitenberg, M.; Kannt, A.; Bamberg, E.; Ludwig, Bernd; Michel, H.; Fendler, K.: Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America 97 (9), pp. 4632 - 4636 (2000)

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Kuglstatter, A.; Miksovska, J.; Sebban, P.; Fritzsch, G.: Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides reconstituted with anthraquinone as primary quinone Q_A. FEBS Letters (1), pp. 114 - 116 (2000)

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Chen, I.-P.; Mathis, P.; Koepke, J.; Michel, H.: Uphill Electron Transfer in the Tetraheme Cytochrome Subunit of the Rhodopseudomonas viridis Photosynthetic Reaction Center: Evidence from Site-Directed Mutagenesis. Biochemistry 39 (13), pp. 3592 - 3602 (2000)

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Arslan, E.; Kannt, A.; Thöny-Meyer, L.; Hennecke, H.: The symbiotically essential cbb₃-type oxidase of Bradyrhizobium japonicum is a proton pump. FEBS Letters 470 (1), pp. 7 - 10 (2000)

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Charnock, J. M.; Dreusch, A.; Körner, H.; Neese, F.; Nelson, J.; Kannt, A.; Michel, H.; Garner, C. D.; Kroneck, P. M.H.; Zumft, W. G.: Structural investigations of the Cu_A centre of nitrous oxide reductase from Pseudomonas stutzeri by site-directed mutagenesis and X-ray absorption spectroscopy. European Journal of Biochemistry 267 (5), pp. 1368 - 1381 (2000)

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Venturi, M.; Rimons, A.; Gerchman, Y.; Hunte, C.; Padan, E.; Michel, H.: The Monoclonal Antibody 1F6 Identifies a pH-dependent Conformational Change in the Hydrophilic NH₂ Terminus of NhaA Na⁺/H⁺ Antiporter of Escherichia coli. The Journal of Biological Chemistry 271 (7), pp. 4734 - 4742 (2000)

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Hampe, W.; Voss, R.-H.; Haase, W.; Boege, F.; Michel, H.; Reiländer, H.: Engineering of a proteolytically stable human β₂-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells. Journal of Biotechnology 77 (2-3), pp. 219 - 234 (2000)

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Selmer, T.; Kahnt, J.; Goubeaud, M.; Shima, S.; Grabarse, W.; Ermler, U.; Thauer, R. K.: The Biosynthesis of Methylated Amino Acids in the Active Site Region of Methyl-coenzyme M Reductase. The Journal of Biological Chemistry 275 (6), pp. 3755 - 3760 (2000)

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Behr, J.; Michel, H.; Mäntele, W.; Hellwig, P.: Functional Properties of the Heme Propionates in Cytochrome c Oxidase from Paracoccus denitrificans. Evidence from FTIR Difference Spectroscopy and Site-Directed Mutagenesis. Biochemistry 39 (6), pp. 1356 - 1363 (2000)

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Maeda, Y.; Kuroki, R.; Suzuki, H.; Reiländer, H.: High-Level Secretion of Biologically Active Recombinant Human Macrophage Inflammatory Protein-1α by the Methylotrophic Yeast Pichia pastoris. Protein Expression and Purification 18 (1), pp. 56 - 63 (2000)

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Harrenga, A.; Reincke, B.; Rüterjans, H.; Ludwig, B.; Michel, H.: Structure of the soluble domain of cytochrome c₅₅₂ from Paracoccus denitrificans in the oxidized and reduced states. Journal of Molecular Biology (London) 295 (3), pp. 667 - 678 (2000)

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