Publications of the Max Planck Institute of Biophysics
Institute Publications Ernst Bamberg Martin Beck Ulrich Ermler Gerhard Hummer Misha Kudryashev Werner Kühlbrandt Julian Langer Hartmut Michel Bonnie Murphy Nadine Schwierz Sonja Welsch Search YearbooksPublications Werner Kühlbrandt
Journal Article (224)
2024
Journal Article
385 (6713), pp. 1086 - 1090 (2024)
In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells. Science
Journal Article
32 (7), pp. 979 - 988.e4 (2024)
Complementary structures of the yeast phosphate transporter Pho90 provide insights into its transport mechanism. Structure 2023
Journal Article
120 (34), e2301447120 (2023)
Two conformations of the Tom20 preprotein receptor in the TOM holo complex. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
9, pp. 142 - 156 (2023)
Cryo-EM structure of the respiratory I + III2 supercomplex from Arabidopsis thaliana at 2 Å resolution. Nature Plants
Journal Article
10 (1), pp. 27 - 37 (2023)
Analysis of the conformational heterogeneity of the Rieske iron–sulfur protein in complex III2 by cryo-EM. IUCrJ 2022
Journal Article
8 (47), eadc9952 (2022)
Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Science Advances
Journal Article
8 (46), eadd3855 (2022)
Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling. Science Advances
Journal Article
240, pp. 323 - 335 (2022)
Concluding remarks: Challenges and future developments in biological electron cryo-microscopy. Faraday Discussions
Journal Article
13 (1), 6091 (2022)
Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations. Nature Communications
Journal Article
13, 2708 (2022)
Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria. Nature Communications
Journal Article
71 (Supplement 1), pp. i30 - i50 (2022)
Forty years in cryoEM of membrane proteins. Microscopy 2021
Journal Article
7 (52), eabk2392 (2021)
Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle. Science Advances
Journal Article
7 (46), eabj3221 (2021)
High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances
Journal Article
7 (46), eabj5255 (2021)
Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances
Journal Article
33 (6), pp. 2072 - 2091 (2021)
A ferredoxin bridge connects the two arms of plant mitochondrial complex I. The Plant Cell
Journal Article
7 (4), pp. 514 - 523 (2021)
Molecular landscape of etioplast inner membranes in higher plants. Nature Plants
Journal Article
54, e4 (2021)
Current limitations to high-resolution structure determination by single-particle cryoEM. Quarterly Reviews of Biophysics
Journal Article
8 (Pt 2), pp. 186 - 194 (2021)
Devitrification reduces beam-induced movement in cryo-EM. IUCrJ 2020
Journal Article
117 (10), pp. 5109 - 5110 (2020)
Reply to Desikan et al.: Micelle formation among various mechanisms of toxin pore formation. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
7 (Pt 2), pp. 220 - 227 (2020)
The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase. IUCrJ
Journal Article
124 (2), pp. 336 - 344 (2020)
Ion Binding and Selectivity of the Na+/H+ Antiporter MjNhaP1 from Experiment and Simulation. The Journal of Physical Chemistry B 2019
Journal Article
5 (12), p. eaax9484 (2019)
High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Science Advances
Journal Article
6, pp. 1099 - 1105 (2019)
A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling. IUCrJ
Journal Article
366 (6461), pp. 100 - 104 (2019)
Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science
Journal Article
571 (7765), pp. 429 - 433 (2019)
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature
Journal Article
571 (7765), pp. 366 - 370 (2019)
Structure and autoregulation of a P4-ATPase lipid flippase. Nature
Journal Article
116 (27), pp. 13352 - 13357 (2019)
Membrane perforation by the pore-forming toxin pneumolysin. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
6 (4), pp. 773 - 780 (2019)
Cryo-EM structure of Neurospora crassa respiratory complex IV. IUCrJ
Journal Article
13 (6), pp. 7185 - 7190 (2019)
Noncovalent Functionalization of Carbon Substrates with Hydrogels Improves Structural Analysis of Vitrified Proteins by Electron Cryo-Microscopy. ACS Nano
Journal Article
364 (6446), eaaw9128, p. 1155 (2019)
Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Science
Journal Article
10, 1742 (2019)
Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting. Nature Communications
Journal Article
8, e42747 (2019)
Protein denaturation at the air-water interface and how to prevent it. eLife
Journal Article
116 (10), pp. 4250 - 4255 (2019)
Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
88, pp. 515 - 549 (2019)
Structure and Mechanisms of F-Type ATP Synthases. Annual Review of Biochemistry 2018
Journal Article
7, e39213 (2018)
Cryo-EM structure of respiratory complex I at work. eLife
Journal Article
9, 1728 (2018)
Structural basis for energy transduction by respiratory alternative complex III. Nature Communications
Journal Article
115 (12), pp. 3024 - 3029 (2018)
Conserved in situ arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
115 (13), pp. E2906 - E2907 (2018)
Structure of the catalytic F1 head of the F1-Fo ATP synthase from Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
360 (6389), pp. 1 - 10 (2018)
Structure, mechanism, and regulation of the chloroplast ATP synthase. Science 2017
Journal Article
6, 10.7554/eLife.30483 (2017)
Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus. eLife
Journal Article
6, e33274 (2017)
Structural basis of proton translocation and force generation in mitochondrial ATP synthase. eLife
Journal Article
170 (4), pp. 693 - 700 (2017)
Cryo-EM Structure of the TOM Core Complex from Neurospora crassa. Cell
Journal Article
6, e24662 (2017)
Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife
Journal Article
6, e27470 (2017)
Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery. eLife
Journal Article
6, e23644 (2017)
CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin. eLife
Journal Article
114 (5), pp. 992 - 997 (2017)
In situ structure of trypanosomal ATP synthase dimer reveals a unique arrangement of catalytic subunits. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
8, 2073, p. 1 (2017)
Structure of outer membrane protein G in lipid bilayers. Nature Communications
Journal Article
11 (6), pp. 6467 - 6473 (2017)
Self-Perforated Hydrogel Nanomembranes Facilitate Structural Analysis of Proteins by Electron Cryo-Microscopy. ACS Nano
Journal Article
18 (6), pp. 1 - 10 (2017)
Molecular architecture of the N‐type ATPase rotor ring from Burkholderia pseudomallei. EMBO Reports
Journal Article
24 (2), pp. 123 - 130 (2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2. Nature Structural and Molecular Biology 2016
Journal Article
291 (52), pp. 26786 - 26793 (2016)
Electrogenic Cation Binding in the Electroneutral Na+/H+ Antiporter of Pyrococcus abyssi. The Journal of Biological Chemistry
Journal Article
5, e21290 (2016)
Functional asymmetry and electron flow in the bovine respirasome. eLife
Journal Article
5, e14618 (2016)
A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro. eLife
Journal Article
1857 (12), pp. 1935 - 1942 (2016)
Cryo-EM structure of respiratory complex I reveals a link to mitochondrial sulfur metabolism. Biochimica et Biophysica Acta (BBA) - Bioenergetics
Journal Article
194 (3), pp. 375 - 382 (2016)
Supramolecular organization of the human N-BAR domain in shaping the sarcolemma membrane. Journal of Structural Biology
Journal Article
63, pp. 1 - 12 (2016)
Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology. Molecular Cell
Journal Article
35 (8), pp. 793 - 795 (2016)
Three in a row - how sodium ions cross the channel. The EMBO Journal
Journal Article
41 (1), pp. 106 - 116 (2016)
Rotary ATPases: A New Twist to an Ancient Machine. Trends in biochemical sciences
Journal Article
113 (30), pp. 8442 - 8447 (2016)
Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
3 (1), pp. 3 - 7 (2016)
CryoEM at IUCrJ: a new era. International Union of Crystallography Journal (IUCrJ) 2015
Journal Article
4, e09375 (2015)
Mechanism of Na+-dependent citrate transport from the structure of an asymmetrical CitS dimer. eLife
Journal Article
13 (89), pp. 1 - 11 (2015)
Structure and function of mitochondrial membrane protein complexes. BMC Biology
Journal Article
153 (June), pp. 22 - 31 (2015)
Towards an optimum design for electrostatic phase plates. Ultramicroscopy
Journal Article
4, e07380 (2015)
Structure of a type IV pilus machinery in the open and closed state. eLife
Journal Article
521, pp. 237 - 240 (2015)
Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase. Nature
Journal Article
4, e06119 (2015)
Bovine F1F0 ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife
Journal Article
21 (5), pp. 747 - 755 (2015)
Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System. Cell Metabolism
Journal Article
112 (36), pp. 11288 - 11293 (2015)
Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
427 (2), pp. 341 - 349 (2015)
Light-Induced Helix Movements in Channelrhodopsin-2. J. Mol. Biol.
Journal Article
119 (10), pp. 3920 - 3930 (2015)
Protein Dynamics Tunes Excited State Positions in Light-Harvesting Complex II. The Journal of Physical Chemistry B 2014
Journal Article
3, e03583 (2014)
Structure and transport mechanism of the sodium/proton antiporter MjNhaP1. eLife
Journal Article
3, e03579 (2014)
Structure and substrate ion binding in the sodium/proton antiporter PaNhaP. eLife
Journal Article
21 (10), pp. 841 - 845 (2014)
A 3D cellular context for the macromolecular world. Nature Structural and Molecular Biology
Journal Article
3, e03678 (2014)
Microscopy: Cryo-EM enters a new era. eLife
Journal Article
5, 4129 (2014)
Visualizing active membrane protein complexes by electron cryotomography. Nature Communications
Journal Article
289, pp. 13168 - 13176 (2014)
Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+. The Journal of Biological Chemistry
Journal Article
343 (6178), pp. 1443 - 1444 (2014)
The Resolution Revolution. Science
Journal Article
3, e01963 (2014)
Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector. eLife
Journal Article
3, e01412 (2014)
pH- and sodium-induced changes in a sodium/proton antiporter. eLife
Journal Article
111 (10), pp. 3829 - 3834 (2014)
Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography. Journal of Visualized Experiments (91 doi: 10.3791/51228), e51228 (2014)
Journal Article
5, 3690 (2014)
Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation. Nature Communications
Journal Article
23 (10), pp. 2580 - 2592 (2014)
Loss of LRPPRC causes ATP synthase deficiency. Human Molecular Genetics 2013
Journal Article
87 (24), pp. 13379 - 13385 (2013)
First insights into the entry process of hyperthermophilic archaeal viruses. Journal of Virology
Journal Article
110 (43), pp. 17296 - 17301 (2013)
Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
110 (38), pp. 15301 - 15306 (2013)
Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
110 (14), pp. 5452 - 5456 (2013)
Direct interaction of the major light-harvesting complex II and PsbS in nonphotochemical quenching. Proceedings of the National Academy of Sciences of the United States of America 2012
Journal Article
109 (34), pp. 13602 - 13607 (2012)
Structure of the yeast F1F0-ATP synthase dimer and its role in shaping the mitochondrial cristae. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
51 (33), pp. 8343 - 8347 (2012)
GRecon: A Method for the Lipid Reconstitution of Membrane Proteins. Angewandte Chemie, International Edition in English
Journal Article
116, pp. 62 - 72 (2012)
Practical aspects of Boersch phase contrast electron microscopy of biological specimens. Ultramicroscopy
Journal Article
1 (1), pp. 21 - 28 (2012)
Structure of the SecY Complex Unlocked by a Preprotein Mimic. Cell Reports 2011
Journal Article
111 (12), pp. 1696 - 1705 (2011)
In-focus electron microscopy of frozen-hydrated biological samples with a Boersch phase plate. Ultramicroscopy
Journal Article
286 (47), pp. 40954 - 40961 (2011)
Structure of Human Na+/H+ Exchanger NHE1 Regulatory Region in Complex with Calmodulin and Ca2+. The Journal of Biological Chemistry
Journal Article
414 (1), pp. 86 - 95 (2011)
Projection Structure of Channelrhodopsin-2 at 6 Å Resolution by Electron Crystallography. Journal of Molecular Biology
Journal Article
13 (11), pp. 1744 - 1754 (2011)
Outer membrane continuity and septosome formation between vegetative cells in the filaments of Anabaena sp. PCC 7120. Cellular Microbiology
Journal Article
99 (3), 133701 (2011)
Single-walled carbon nanotubes and nanocrystalline graphene reduce beam-induced movements in high-resolution electron cryo-microscopy of ice-embedded biological samples. Applied Physics Letters
Journal Article
108 (34), pp. 14121 - 14126 (2011)
Macromolecular organization of ATP synthase and complex I in whole mitochondria. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
108 (33), pp. 13841 - 13846 (2011)
Chloroplast Omp85 proteins change orientation during evolution. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
40, pp. 379 - 408 (2011)
Amphipols From A to Z. Annual Review of Biophysics