Publications of Winfried Siffert

Quednau, B.; Rosskopf, D.; Frömter, E.; Siffert, W.: Enhanced Na⁺-H⁺ exchanger activity and NHE-1 mRNA levels in human lymphocytes during metabolic acidosis. American Journal of Physiology: Cell Physiology 266 (2 Pt 1), pp. C480 - C488 (1994)

Rosskopf, D.; Frömter, E.; Siffert, W.: Hypertensive sodium-proton exchanger phenotype persists in immortalized lymphoblasts from essential hypertensive patients. A cell culture model for human hypertension. The Journal of Clinical Investigation 92 (5), pp. 2553 - 2559 (1993)

Nieuwland, R.; Siffert, W.; Akkerman, J.-W. N.: Effect of epinephrine on the regulation of Na⁺/H⁺ exchange in human platelets. Biochimica et Biophysica Acta-Biomembranes 1148 (2), pp. 185 - 190 (1993)

Rosskopf, D.; Düsing, R.; Siffert, W.: Membrane sodium-proton exchange and primary hypertension. Hypertension 21 (5), pp. 607 - 617 (1993)

Stamouli, V.; Vakirtzi-Lemonias, C.; Siffert, W.: Thrombin and NaF, but not epinephrine, raise cytosolic free Na⁺ in human platelets. Biochimica et Biophysica Acta-Molecular Cell Research 1176 (3), pp. 215 - 221 (1993)

Düsing, R.; Sorger, M.; Mattes, L.; Göbel, B.O.; Hoffmann, G.; Rosskopf, D.; Vetter, H.; Siffert, W.: Platelet Na⁺/H⁺ antiport activity in patients with insulin-dependent diabetes mellitus with and without diabetic nephropathy. the clinical investigator 71, pp. 119 - 125 (1993)

Juntti-Berggren, L.; Rorsman, P.; Siffert, W.; Berggren, P.-O.: Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells. Biochemical Journal 287 (1), pp. 59 - 66 (1992)

Rosskopf, D.; Siffert, G.; Osswald, U.; Witte, K.; Düsing, R.; Akkerman, J. W.; Siffert, W.: Platelet Na⁺-H⁺ exchanger activity in normotensive and hypertensive subjects: effect of enalapril therapy upon antiport activity. Journal of Hypertension 10 (8), pp. 839 - 847 (1992)

Quednau, B.; Rosskopf, D.; Weiler-Güttler, H.; Siffert, W.: Detection of Na⁺/H⁺ exchanger mRNA in human neutrophils and lymphocytes using the polymerase chain reaction. FEBS Letters 289 (2), pp. 221 - 223 (1991)

Borin, M.; Siffert, W.: Further characterization of the mechanisms mediating the rise in cytosolic free Na⁺ in thrombin-stimulated platelets. Evidence for inhibition of the Na⁺,K⁺-ATPase and for Na⁺ entry via a Ca²⁺ influx pathway. The Journal of Biological Chemistry 266 (20), pp. 13153 - 13160 (1991)

Rosskopf, D.; Barth, C.; Siffert, W.: Estimation of carrier density and turnover rate of the Na⁺/H⁺ exchanger in human platelets using 5-(N-methyl-N-[³H]isobutyl)- amiloride. Biochemical and Biophysical Research Communications 176 (2), pp. 639 - 644 (1991)

Rosskopf, D.; Morgenstern, E.; Scholz, W.; Osswald, U.; Siffert, W.: Rapid determination of the elevated Na⁺-H⁺ exchange in platelets of patients with essential hypertension using an optical swelling assay. Journal of Hypertension 9 (3), pp. 231 - 238 (1991)

Borin, M.; Siffert, W.: Stimulation by thrombin increases the cytosolic free Na⁺ concentration in human platelets. Studies with the novel fluorescent cytosolic Na⁺ indicator sodium-binding benzofuran isophthalate. The Journal of Biological Chemistry 265 (32), pp. 19543-50 - 19550 (1990)

Siffert, W.; Jakobs, K. H.; Akkerman, J. W. N.: Sodium fluoride prevents receptor- and protein kinase C-mediated activation of the human platelet Na⁺/H⁺ exchanger without inhibiting its basic pH_i-regulating activity. The Journal of Biological Chemistry 265 (26), pp. 15441 - 15448 (1990)

Joseph, S.; Siffert, W.; Gorter, G.; Akkerman, J.-W. N.: Stimulation of human platelets by collagen occurs by a Na⁺/H⁺ exchanger independent mechanism. Biochimica et Biophysica Acta-Molecular Cell Research 1054 (1), pp. 26 - 32 (1990)

Clemens, N.; Siffert, W.; Scheid, P.: Thrombin-induced cytosolic alkalinization in human platelets occurs without an apparent involvement of HCO₃^-/Cl^- exchange. Pflügers Archiv: European Journal of Physiology 416 (1-2), pp. 68 - 73 (1990)

Siffert, W.; Akkerman, . W. N.: Na⁺/H⁺ exchange and Ca²⁺ influx. FEBS Letters 259 (1), pp. 1 - 4 (1989)

Siffert, W.; Akkerman, J. W. N.: Cytosolic alkalinization alone is not sufficient for Ca²⁺ mobilization, phosphatidic acid formation, and protein phosphorylation in human platelets. Biochemical and Biophysical Research Communications 161 (3), pp. 1007 - 1012 (1989)