Publications of the Max Planck Institute of Biophysics

Publications of the Max Planck Institute of Biophysics

Institute Publications Ernst Bamberg Martin Beck Ulrich Ermler Gerhard Hummer Misha Kudryashev Werner Kühlbrandt Julian Langer Hartmut Michel Bonnie Murphy Nadine Schwierz Sonja Welsch Search Yearbooks

Publications Martin Beck

Journal Article (107)

1.
Journal Article
Beck, M.; Covino, R.; Hänelt, I.; Müller-McNicoll, M.: Understanding the cell: Future views of structural biology. Cell 187 (3), pp. 545 - 562 (2024)
2.
Journal Article
Jagtap, P. K. A.; Müller, M.; Kiss, A. E.; Thomae, A. W.; Lapouge, K.; Beck, M.; Becker, P. B.; Hennig, J.: Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Molecular Cell 83, pp. 4318 - 4333 (2023)
3.
Journal Article
Sanchez Carrillo, I. B.; Hoffmann, P. C.; Barff, T.; Beck, M.; Germain, H.: Preparing Arabidopsis thaliana root protoplasts for cryo electron tomography. Frontiers in Plant Science 14, 1261180 (2023)
4.
Journal Article
Castillo Duque de Estrada, N. M.; Thoms, M.; Flemming, D.; Hammaren, H. M.; Buschauer, R.; Ameismeier, M.; Baßler, J.; Beck, M.; Beckmann, R.; Hurt, E.: Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways. Nature Structural and Molecular Biology 30, pp. 1119 - 1131 (2023)
5.
Journal Article
Xing, H.; Taniguchi, R.; Khusainov, I.; Kreysing, J. P.; Welsch, S.; Turoňová, B.; Beck, M.: Translation dynamics in human cells visualized at high resolution reveal cancer drug action. Science 381 (6653), pp. 70 - 75 (2023)
6.
Journal Article
Seidel, M.; Romanov, N.; Obarska-Kosinska, A.; Becker, A.; Trevisan Doimo de Azevedo, N.; Provaznik, J.; Nagaraja, S. R.; Landry, J. J. M.; Benes, V.; Beck, M.: Co-translational binding of importins to nascent proteins. Nature Communications 14, 3418 (2023)
7.
Journal Article
Yu, M.; Heidari, M.; Mikhaleva, S.; Tan, P. S.; Mingu, S.; Ruan, H.; Reinkemeier, C. D.; Obarska-Kosinska, A.; Siggel, M.; Beck, M. et al.; Hummer, G.; Lemke, E. A.: Visualizing the disordered nuclear transport machinery in situ. Nature 617 (7959), pp. 162 - 169 (2023)
8.
Journal Article
de Teresa-Trueba, I.; Goetz, S. K.; Mattausch, A.; Stojanovska, F.; Zimmerli, C. E.; Toro-Nahuelpan, M.; Cheng, D. W. C.; Tollervey, F.; Pape, C.; Beck, M. et al.; Diz-Muñoz, A.; Kreshuk, A.; Mahamid, J.; Zaugg, J. B.: Convolutional networks for supervised mining of molecular patterns within cellular context. Nature Methods 20 (2), pp. 284 - 294 (2023)
9.
Journal Article
Miyazawa, H.; Snaebjornsson, M. T.; Prior, N.; Kafkia, E.; Hammarén, H. M.; Tsuchida-Straeten, N.; Patil, K. R.; Beck, M.; Aulehla, A.: Glycolytic flux-signaling controls mouse embryo mesoderm development. eLife 11, e83299 (2022)
10.
Journal Article
Hammarén, H. M.; Geissen, E.-M.; Potel, C. M.; Beck, M.; Savitski, M. M.: Protein-Peptide Turnover Profiling reveals the order of PTM addition and removal during protein maturation. Nature Communications 13, 7431 (2022)
11.
Journal Article
Hoffmann, P. C.; Kreysing, J. P.; Khusainov, I.; Tuijtel, M.; Welsch, S.; Beck, M.: Structures of the eukaryotic ribosome and its translational states in situ. Nature Communications 13, 7435 (2022)
12.
Journal Article
Kafkia, E.; Andres-Pons, A.; Ganter, K.; Seiler, M.; Smith, T. S.; Andrejeva, A.; Jouhten, P.; Pereira, F.; Franco, C.; Kuroshchenkova, A. et al.; Leone, S.; Sawarkar, R.; Boston, R.; Thaventhiran, J.; Zaugg, J. B.; Lilley, K. S.; Lancrin, C.; Beck, M.; Patil, K. R.: Operation of a TCA cycle subnetwork in the mammalian nucleus. Science Advances 8 (35), eabq5206 (2022)
13.
Journal Article
Mosalaganti, S.; Obarska-Kosinska, A.; Siggel, M.; Taniguchi, R.; Turoňová, B.; Zimmerli, C. E.; Buczak, K.; Schmidt, F. H.; Margiotta, E.; Mackmull, M.-T. et al.; Hagen, W. J. H.; Hummer, G.; Kosinski, J.; Beck, M.: AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science 376 (6598), eabm9506 (2022)
14.
Journal Article
Di Fraia, D.; Anitei, M.; Mackmull, M.-T.; Parca, L.; Behrendt, L.; Andres-Pons, A.; Gilmour, D.; Helmer Citterich, M.; Kaether, C.; Beck, M. et al.; Ori, A.: Conserved exchange of paralog proteins during neuronal differentiation. Life science alliance 5 (6), e202201397 (2022)
15.
Journal Article
Seidel, M.; Becker, A.; Pereira, F.; Landry, J. J. M.; de Azevedo, N. T. D.; Fusco, C. M.; Kaindl, E.; Romanov, N.; Baumbach, J.; Langer, J. D. et al.; Schuman, E. M.; Patil, K. R.; Hummer, G.; Benes, V.; Beck, M.: Co-translational assembly orchestrates competing biogenesis pathways. Nature Communications 13, 1224 (2022)
16.
Journal Article
Klumpe, S.; Fung, H. K. H.; Goetz, S. K.; Zagoriy, I.; Hampoelz, B.; Zhang, X.; Erdmann, P. S.; Baumbach, J.; Müller, C. W.; Beck, M. et al.; Plitzko, J. M.; Mahamid, J.: A modular platform for automated cryo-FIB workflows. eLife 10, e70506 (2021)
17.
Journal Article
Zimmerli, C. E.; Allegretti, M.; Rantos, V.; Goetz, S. K.; Obarska-Kosinska, A.; Zagoriy, I.; Halavatyi, A.; Hummer, G.; Mahamid, J.; Kosinski, J. et al.; Beck, M.: Nuclear pores dilate and constrict in cellulo. Science 374 (6573), eabd9776 (2021)
18.
Journal Article
Musser, J. M.; Schippers, K. J.; Nickel, M.; Mizzon, G.; Kohn, A. B.; Pape, C.; Ronchi, P.; Papadopoulos, N.; Tarashansky, A. J.; Hammel, J. U. et al.; Wolf, F.; Liang, C.; Hernández-Plaza, A.; Cantalapiedra, C. P.; Achim, K.; Schieber, N. L.; Pan, L.; Ruperti, F.; Francis, W. R.; Vargas, S.; Kling, S.; Renkert, M.; Polikarpov, M.; Bourenkov, G.; Feuda, R.; Gaspar, I.; Burkhardt, P.; Wang, B.; Bork, P.; Beck, M.; Schneider, T. R.; Kreshuk, A.; Wörheide, G.; Huerta-Cepas, J.; Schwab, Y.; Moroz, L. L.; Arendt, D.: Profiling cellular diversity in sponges informs animal cell type and nervous system evolution. Science 374 (6568), pp. 717 - 723 (2021)
19.
Journal Article
Klünemann, M.; Andrejev, S.; Blasche, S.; Mateus, A.; Phapale, P.; Devendran, S.; Vappiani, J.; Simon, B.; Scott, T. A.; Kafkia, E. et al.; Konstantinidis, D.; Zirngibl, K.; Mastrorilli, E.; Banzhaf, M.; Mackmull, M.-T.; Hövelmann, F.; Nesme, L.; Brochado, A. R.; Maier, L.; Bock, T.; Periwal, V.; Kumar, M.; Kim, Y.; Tramontano, M.; Schultz, C.; Beck, M.; Hennig, J.; Zimmermann, M.; Sévin, D. C.; Cabreiro, F.; Savitski, M. M.; Bork, P.; Typas, A.; Patil, K. R.: Bioaccumulation of therapeutic drugs by human gut bacteria. Nature 597 (7877), pp. 533 - 538 (2021)
20.
Journal Article
Sabinina, V. J.; Hossain, M. J.; Hériché, J.-K.; Hoess, P.; Nijmeijer, B.; Mosalaganti, S.; Kueblbeck, M.; Callegari, A.; Szymborska, A.; Beck, M. et al.; Ries, J.; Ellenberg, J.: Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex. Molecular Biology of the Cell 32 (17), pp. 1523 - 1533 (2021)
21.
Journal Article
Li, Y.; Kuhn, M.; Zukowska-Kasprzyk, J.; Hennrich, M. L.; Kastritis, P. L.; O’Reilly, F. J.; Phapale, P.; Beck, M.; Gavin, A.-C.; Bork, P.: Coupling proteomics and metabolomics for the unsupervised identification of protein–metabolite interactions in Chaetomium thermophilum. PLoS One 16 (7), e0254429 (2021)
22.
Journal Article
Zila, V.; Margiotta, E.; Turoňová, B.; Müller, T. G.; Zimmerli, C. E.; Mattei, S.; Allegretti, M.; Börner, K.; Rada, J.; Müller, B. et al.; Lusic, M.; Kräusslich, H.-G.; Beck, M.: Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell 184 (4), pp. 1032 - 1046 (2021)
23.
Journal Article
Bárcena, M.; Barnes, C. O.; Beck, M.; Bjorkman, P. J.; Canard, B.; Gao, G. F.; Gao, Y.; Hilgenfeld, R.; Hummer, G.; Patwardhan, A. et al.; Santoni, G.; Saphire, E. O.; Schaffitzel, C.; Schendel, S. L.; Smith, J. L.; Thorn, A.; Veesler, D.; Zhang, P.; Zhou, Q.: Structural biology in the fight against COVID-19. Nature Structural and Molecular Biology 28 (1), pp. 2 - 7 (2021)
24.
Journal Article
Allegretti, M.; Zimmerli, C. E.; Rantos, V.; Wilfing, F.; Ronchi, P.; Fung, H. K. H.; Lee, C.-W.; Hagen, W.; Turoňová, B.; Karius, K. et al.; Börmel, M.; Zhang, X.; Müller, C. W.; Schwab, Y.; Mahamid, J.; Pfander, B.; Kosinski, J.; Beck, M.: In-cell architecture of the nuclear pore and snapshots of its turnover. Nature 586 (7831), pp. 796 - 800 (2020)
25.
Journal Article
Turoňová, B.; Sikora, M.; Schürmann, C.; Hagen, W. J. H.; Welsch, S.; Blanc, F. E. C.; von Bülow, S.; Gecht, M.; Bagola, K.; Hörner, C. et al.; van Zandbergen, G.; Landry, J.; de Azevedo, N. T. D.; Mosalaganti, S.; Schwarz, A.; Covino, R.; Mühlebach, M. D.; Hummer, G.; Krijnse Locker, J.; Beck, M.: In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science 370 (6513), pp. 203 - 208 (2020)
26.
Journal Article
Zhou, Y.; Kastritis, P. L.; Dougherty, S. E.; Bouvette, J.; Hsu, A. L.; Burbaum, L.; Mosalaganti, S.; Pfeffer, S.; Hagen, W. J. H.; Förster, F. et al.; Borgnia, M. J.; Vogel, C.; Beck, M.; Bartesaghi, A.; Silva, G. M.: Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proceedings of the National Academy of Sciences of the United States of America 117 (36), pp. 22157 - 22166 (2020)
27.
Journal Article
Buczak, K.; Kirkpatrick, J. M.; Truckenmueller, F.; Santinha, D.; Ferreira, L.; Roessler, S.; Singer, S.; Beck, M.; Ori, A.: Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. Nature Protocols 15 (9), pp. 2956 - 2979 (2020)
28.
Journal Article
Lee, B.-G.; Merkel, F.; Allegretti, M.; Hassler, M.; Cawood, C.; Lecomte, L.; O'Reilly, F. J.; Sinn, L. R.; Gutierrez-Escribano, P.; Kschonsak, M. et al.; Bravo, S.; Nakane, T.; Rappsilber, J.; Aragon, L.; Beck, M.; Löwe, J.; Haering, C. H.: Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nature Structural and Molecular Biology 27 (8), pp. 743 - 751 (2020)
29.
Journal Article
Turoňová, B.; Hagen, W. J. H.; Obr, M.; Mosalaganti, S.; Beugelink, J. W.; Zimmerli, C. E.; Kräusslich, H.-G.; Beck, M.: Benchmarking tomographic acquisition schemes for high-resolution structural biology. Nature Communications 11, 876 (2020)
30.
Journal Article
Fürsch, J.; Kammer, K.-M.; Kreft, S. G.; Beck, M.; Stengel, F.: Proteome-Wide Structural Probing of Low-Abundant Protein Interactions by Cross-Linking Mass Spectrometry. Analytical Chemistry 92 (5), pp. 4016 - 4022 (2020)
31.
Journal Article
Lee, C.-W.; Wilfling, F.; Ronchi, P.; Allegretti, M.; Mosalaganti, S.; Jentsch, S.; Beck, M.; Pfander, B.: Selective autophagy degrades nuclear pore complexes. Nature Cell Biology 22 (2), pp. 159 - 166 (2020)
32.
Journal Article
Guo, T.; Luna, A.; Rajapakse, V. N.; Koh, C. C.; Wu, Z.; Liu, W.; Sun, Y.; Gao, H.; Menden, M. P.; Xu, C. et al.; Calzone, L.; Martignetti, L.; Auwerx, C.; Buljan, M.; Banaei-Esfahani, A.; Ori, A.; Iskar, M.; Gillet, L.; Bi, R.; Zhang, J.; Zhang, H.; Yu, C.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Zhang, Q.; Zhu, Y.; Wild, P. J.; Garnett, M. J.; Bork, P.; Beck, M.; Liu, K.; Saez-Rodriguez, J.; Elloumi, F.; Reinhold, W. C.; Sander, C.; Pommier, Y.; Aebersold, R.: Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines. iScience 21, pp. 664 - 680 (2019)
33.
Journal Article
Hampoelz, B.; Schwarz, A.; Ronchi, P.; Bragulat-Teixidor, H.; Tischer, C.; Gaspar, I.; Ephrussi, A.; Schwab, Y.; Beck, M.: Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell 179 (3), pp. 671 - 686.e17 (2019)
34.
Journal Article
Schwarz, A.; Beck, M.: The Benefits of Cotranslational Assembly: A Structural Perspective. Trends in Cell Biology 29 (10), pp. 791 - 803 (2019)
35.
Journal Article
Romanov, N.; Kuhn, M.; Aebersold, R.; Ori, A.; Beck, M.; Bork, P.: Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals. Cell 177 (5), pp. 1308 - 1318 (2019)
36.
Journal Article
Holzer, K.; Ori, A.; Cooke, A.; Dauch, D.; Drucker, E.; Riemenschneider, P.; Andres-Pons, A.; DiGuilio, A. L.; Mackmull, M.-T.; Baßler, J. et al.; Roessler, S.; Breuhahn, K.; Zender, L.; Glavy, J. S.; Dombrowski, F.; Hurt, E.; Schirmacher, P.; Beck, M.; Singer, S.: Nucleoporin Nup155 is part of the p53 network in liver cancer. Nature Communications 10, 2147 (2019)
37.
Journal Article
Hampoelz, B.; Andres-Pons, A.; Kastritis, P.; Beck, M.: Structure and Assembly of the Nuclear Pore Complex. Annual Review of Biophysics 48, pp. 515 - 536 (2019)
38.
Journal Article
Thaller, D. J.; Allegretti, M.; Borah, S.; Ronchi, P.; Beck, M.; Lusk, C. P.: An ESCRT-LEM Protein Surveillance System Is Poised to Directly Monitor the Nuclear Envelope and Nuclear Transport System. eLife 8, e45284 (2019)
39.
Journal Article
Beck, M.; Mosalaganti, S.; Kosinski, J.: From the resolution revolution to evolution: structural insights into the evolutionary relationships between vesicle coats and the nuclear pore. Current Opinion in Structural Biology 52, pp. 32 - 40 (2018)
40.
Journal Article
Kehrer, J.; Kuss, C.; Andres-Pons, A.; Reustle, A.; Dahan, N.; Devos, D.; Kudryashev, M.; Beck, M.; Mair, G. R.; Frischknecht, F.: Nuclear Pore Complex Components in the Malaria Parasite Plasmodium Berghei. Scientific Reports 8, 11249 (2018)
41.
Journal Article
Parca, L.; Beck, M.; Bork, P.; Ori, A.: Quantifying compartment-associated variations of protein abundance in proteomics data. Molecular Systems Biology 14 (7), e8131 (2018)
42.
Journal Article
Mosalaganti, S.; Kosinski, J.; Albert, S.; Schaffer, M.; Strenkert, D.; Salomé, P. A.; Merchant, S. S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D. et al.; Beck, M.: In situ architecture of the algal nuclear pore complex. Nature Communications 9 (1), 2361 (2018)
43.
Journal Article
Becher, I.; Andrés-Pons, A.; Romanov, N.; Stein, F.; Schramm, M.; Baudin, F.; Helm, D.; Kurzawa, N.; Mateus, A.; Mackmull, M.-T. et al.; Typas, A.; Müller, C. W.; Bork, P.; Beck, M.; Savitski, M. M.: Pervasive Protein Thermal Stability Variation During the Cell Cycle. Cell 173 (6), pp. 1495 - 1507 (2018)
44.
Journal Article
Buczak, K.; Ori, A.; Kirkpatrick, J. M.; Holzer, K.; Dauch, D.; Roessler, S.; Endris, V.; Lasitschka, F.; Parca, L.; Schmidt, A. et al.; Zender, L.; Schirmacher, P.; Krijgsveld, J.; Singer, S.; Beck, M.: Spatial Tissue Proteomics Quantifies Inter- And Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). Molecular and Cellular Proteomics 17 (4), pp. 810 - 825 (2018)
45.
Journal Article
Mathieson, T.; Franken, H.; Kosinski, J.; Kurzawa, N.; Zinn, N.; Sweetman, G.; Poeckel, D.; Ratnu, V. S.; Schramm, M.; Becher, I. et al.; Steidel, M.; Noh, K.-M.; Bergamini, G.; Beck, M.; Bantscheff, M.; Savitski, M. M.: Systematic analysis of protein turnover in primary cells. Nature Communications 9, 689 (2018)
46.
Journal Article
Otsuka, S.; Steyer, A. M.; Schorb, M.; Hériché, J.-K.; Hossain, M. J.; Sethi, S.; Kueblbeck, M.; Schwab, Y.; Beck, M.; Ellenberg, J.: Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings. Nature Structural and Molecular Biology 25 (1), pp. 21 - 28 (2018)
47.
Journal Article
Albert, S.; Schaffer, M.; Beck, F.; Mosalaganti, S.; Asano, S.; Thomas, H. F.; Plitzko, J. M.; Beck, M.; Baumeister, W.; Engel, B. D.: Proteasomes tether to two distinct sites at the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America 114 (52), pp. 13726 - 13731 (2017)
48.
Journal Article
Mackmull, M.-T.; Klaus, B.; Heinze, I.; Chokkalingam, M.; Beyer, A.; Russell, R. B.; Ori, A.; Beck, M.: Landscape of nuclear transport receptor cargo specificity. Molecular Systems Biology 13 (12), 962 (2017)
49.
Journal Article
Beck, M.; Schirmacher, P.; Singer, S.: Alterations of the nuclear transport system in hepatocellular carcinoma - New basis for therapeutic strategies. Journal of Hepatology 67 (5), pp. 1051 - 1061 (2017)
50.
Journal Article
Teimer, R.; Kosinski, J.; von Appen, A.; Beck, M.; Hurt, E.: A Short Linear Motif in Scaffold Nup145C Connects Y-complex With Pre-Assembled Outer Ring Nup82 Complex. Nature Communications 8, 1107 (2017)
51.
Journal Article
Sadian, Y.; Tafur, L.; Kosinski, J.; Jakobi, A. J.; Wetzel, R.; Buczak, K.; Hagen, W. J.; Beck, M.; Sachse, C.; Müller, C. W.: Structural Insights Into Transcription Initiation by Yeast RNA Polymerase I. The EMBO Journal 36 (18), pp. 2698 - 2709 (2017)
52.
Journal Article
Kastritis, P. L.; O'Reilly, F. J.; Bock, T.; Li, Y.; Rogon, M. Z.; Buczak, K.; Romanov, N.; Betts, M. J.; Bui, K. H.; Hagen, W. J. et al.; Hennrich, M. L.; Mackmull, M.-T.; Rappsilber, J.; Russell, R. B.; Bork, P.; Beck, M.; Gavin, A.-C.: Capturing protein communities by structural proteomics in a thermophilic eukaryote. Molecular Systems Biology 13 (7), 936 (2017)
53.
Journal Article
Beck, M.; Hurt, E.: The nuclear pore complex: understanding its function through structural insight. Nature Reviews Molecular Cell Biology 18 (2), pp. 73 - 89 (2017)
54.
Journal Article
Dauden, M. I.; Kosinski, J.; Kolaj-Robin, O.; Desfosses, A.; Ori, A.; Faux, C.; Hoffmann, N. A.; Onuma, O. F.; Breunig, K. D.; Beck, M. et al.; Sachse, C.; Séraphin, B.; Glatt, S.; Müller, C. W.: Architecture of the yeast Elongator complex. EMBO Journal 18 (2), pp. 264 - 279 (2017)
55.
Journal Article
Scharaw, S.; Iskar, M.; Ori, A.; Boncompain, G.; Laketa, V.; Poser, I.; Lundberg, E.; Perez, F.; Beck, M.; Bork, P. et al.; Pepperkok, R.: The Endosomal Transcriptional Regulator RNF11 Integrates Degradation and Transport of EGFR. The Journal of Cell Biology: JCB 215 (4), pp. 543 - 558 (2016)
56.
Journal Article
Kiosze-Becker, K.; Ori, A.; Gerovac, M.; Heuer, A.; Nürenberg-Goloub, E.; Rashid, U. J.; Becker, T.; Beckmann, R.; Beck, M.; Tampé, R.: Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry. Nature Communications 7, 13248 (2016)
57.
Journal Article
Beck, M.; Baumeister, W.: Cryo-Electron Tomography: Can It Reveal the Molecular Sociology of Cells in Atomic Detail? Trends in Cell Biology 26 (11), pp. 825 - 837 (2016)
58.
Journal Article
Otsuka, S.; Bui, K. H.; Schorb, M.; Hossain, M. J.; Politi, A. Z.; Koch, B.; Eltsov, M.; Beck, M.; Ellenberg, J.: Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope. eLife 5, e19071 (2016)
59.
Journal Article
Hampoelz, B.; Mackmull, M.-T.; Machado, P.; Ronchi, P.; Bui, K. H.; Schieber, N.; Santarella-Mellwig, R.; Necakov, A.; Andrés-Pons, A.; Philippe, J. M. et al.; Lecuit, T.; Schwab, Y.; Beck, M.: Pre-assembled Nuclear Pores Insert Into the Nuclear Envelope During Early Development. Cell 166 (3), pp. 664 - 678 (2016)
60.
Journal Article
Hoelz, A.; Glavy, J. S.; Beck, M.: Toward the atomic structure of the nuclear pore complex: when top down meets bottom up. Nature Structural and Molecular Biology 23 (7), pp. 624 - 630 (2016)
61.
Journal Article
Ferber, M.; Kosinski, J.; Ori, A.; Rashid, U. J.; Moreno-Morcillo, M.; Simon, B.; Bouvier, G.; Batista, P. R.; Müller, C. W.; Beck, M. et al.; Nilges, M.: Automated structure modeling of large protein assemblies using crosslinks as distance restraints. Nature methods 13 (6), pp. 515 - 520 (2016)
62.
Journal Article
von Appen, A.; Beck, M.: Structure Determination of the Nuclear Pore Complex With Three-Dimensional Cryo Electron Microscopy. Journal of Molecular Biology (London) 428 (10 Pt A), pp. 2001 - 2010 (2016)
63.
Journal Article
Kosinski, J.; Mosalaganti, S.; von Appen, A.; Teimer, R.; DiGuilio, A. L.; Wan, W.; Bui, K. H.; Hagen, W. J. H.; Briggs, J. A. G.; Glavy, J. S. et al.; Hurt, E.; Beck, M.: Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science 352 (6283), pp. 363 - 365 (2016)
64.
Journal Article
Ori, A.; Iskar, M.; Buczak, K.; Kastritis, P.; Parca, L.; Andrés-Pons, A.; Singer, S.; Bork, P.; Beck, M.: Spatiotemporal variation of mammalian protein complex stoichiometries. Genome Biology 17, 47 (2016)
65.
Journal Article
Silva-Martin, N.; Daudén, M. I.; Glatt, S.; Hoffmann, N. A.; Kastritis, P.; Bork, P.; Beck, M.; Müller, C. W.: The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex. PLoS One 11 (1), e0146457 (2016)
66.
Journal Article
Thierry, E.; Guilligay, D.; Kosinski, J.; Bock, T.; Gaudon, S.; Round, A.; Pflug, A.; Hengrung, N.; El Omari, K.; Baudin, F. et al.; Hart, D. J.; Beck, M.; Cusack, S.: Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains. Molecular Cell 61 (1), pp. 125 - 137 (2016)
67.
Journal Article
Poli, M.; Ori, A.; Child, T.; Jaroudi, S.; Spath, K.; Beck, M.; Wells, D.: Characterization and quantification of proteins secreted by single human embryos prior to implantation. Embo Molecular Medicine 7 (11), pp. 1465 - 1479 (2015)
68.
Journal Article
von Appen, A.; Kosinski, J.; Sparks, L.; Ori, A.; DiGuilio, A. L.; Vollmer, B.; Mackmull, M.-T.; Banterle, N.; Parca, L.; Kastritis, P. et al.; Buczak, K.; Mosalaganti, S.; Hagen, W.; Andres-Pons, A.; Lemke, E. A.; Bork, P.; Antonin, W.; Glavy, J. S.; Bui, K. H.; Beck, M.: In situ structural analysis of the human nuclear pore complex. Nature 526 (7571), pp. 140 - 143 (2015)
69.
Journal Article
Ori, A.; Toyama, B. H.; Harris, M. S.; Bock, T.; Iskar, M.; Bork, P.; Ingolia, N. T.; Hetzer, M. W.; Beck, M.: Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats. Cell Systems 1 (3), pp. 224 - 237 (2015)
70.
Journal Article
Deniaud, A.; Karuppasamy, M.; Bock, T.; Masiulis, S.; Huard, K.; Garzoni, F.; Kerschgens, K.; Hentze, M. W.; Kulozik, A. E.; Beck, M. et al.; Neu-Yilik, G.; Schaffitzel, C.: A Network of SMG-8, SMG-9 and SMG-1 C-terminal Insertion Domain Regulates UPF1 Substrate Recruitment and Phosphorylation. Nucleic Acids Research (London) 43 (15), pp. 7600 - 7611 (2015)
71.
Journal Article
Dodonova, S. O.; Diestelkoetter-Bachert, P.; von Appen, A.; Hagen, W. J. H.; Beck, R.; Beck, M.; Wieland, F.; Briggs, J. a. G.: VESICULAR TRANSPORT. A Structure of the COPI Coat and the Role of Coat Proteins in Membrane Vesicle Assembly. Science 349 (6244), pp. 195 - 198 (2015)
72.
Journal Article
Male, G.; von Appen, A.; Glatt, S.; Taylor, N. M. I.; Cristovao, M.; Groetsch, H.; Beck, M.; Müller, C. W.: Architecture of TFIIIC and Its Role in RNA Polymerase III Pre-Initiation Complex Assembly. Nature Communications 6, 7387 (2015)
73.
Journal Article
Hurt, E.; Beck, M.: Towards understanding nuclear pore complex architecture and dynamics in the age of integrative structural analysis. Current Opinion in Cell Biology 34, pp. 31 - 38 (2015)
74.
Journal Article
Mackmull, M.-T.; Iskar, M.; Parca, L.; Singer, S.; Bork, P.; Ori, A.; Beck, M.: Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). Molecular and Cellular Proteomics 14 (5), pp. 1350 - 1360 (2015)
75.
Journal Article
Calviño, F. R.; Kharde, S.; Ori, A.; Hendricks, A.; Wild, K.; Kressler, D.; Bange, G.; Hurt, E.; Beck, M.; Sinning, I.: Symportin 1 Chaperones 5S RNP Assembly During Ribosome Biogenesis by Occupying an Essential rRNA-binding Site. Nature Communications 6, 6510 (2015)
76.
Journal Article
Kosinski, J.; von Appen, A.; Ori, A.; Karius, K.; Müller, C. W.; Beck, M.: Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures. Journal of Structural Biology 189 (3), pp. 177 - 183 (2015)
77.
Journal Article
Gaik, M.; Flemming, D.; von Appen, A.; Kastritis, P.; Mücke, N.; Fischer, J.; Stelter, P.; Ori, A.; Bui, K. H.; Baßler, J. et al.; Barbar, E.; Beck, M.; Hurt, E.: Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. The Journal of Cell Biology: JCB 208 (3), pp. 283 - 297 (2015)
78.
Journal Article
Bock, T.; Chen, W.-H.; Ori, A.; Malik, N.; Silva-Martin, N.; Huerta-Cepas, J.; Powell, S. T.; Kastritis, P. L.; Smyshlyaev, G.; Vonkova, I. et al.; Kirkpatrick, J.; Doerks, T.; Nesme, L.; Baßler, J.; Kos, M.; Hurt, E.; Carlomagno, T.; Gavin, A.-C.; Barabas, O.; Müller, C. W.; van Noort, V.; Beck, M.; Bork, P.: An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum. Nucleic Acids Research (London) 42 (22), pp. 13525 - 13533 (2014)
79.
Journal Article
Ostenfeld, M. S.; Jeppesen, D. K.; Laurberg, J. R.; Boysen, A. T.; Bramsen, J. B.; Primdal-Bengtson, B.; Hendrix, A.; Lamy, P.; Dagnaes-Hansen, F.; Rasmussen, M. H. et al.; Bui, K. H.; Fristrup, N.; Christensen, E. I.; Nordentoft, I.; Morth, J. P.; Jensen, J. B.; Pedersen, J. S.; Beck, M.; Theodorescu, D.; Borre, M.; Howard, K. A.; Dyrskjøt, L.; Ørntoft, T. F.: Cellular Disposal of miR23b by RAB27-dependent Exosome Release Is Linked to Acquisition of Metastatic Properties. Cancer research: an official organ of the American Association for Cancer Research 74 (20), pp. 5758 - 5771 (2014)
80.
Journal Article
Winkler, J.; Ori, A.; Holzer, K.; Sticht, C.; Dauch, D.; Eiteneuer, E. M.; Pinna, F.; Geffers, R.; Ehemann, V.; Andres-Pons, A. et al.; Breuhahn, K.; Longerich, T.; Bermejo, J. L.; Gretz, N.; Zender, L.; Schirmacher, P.; Beck, M.; Singer, S.: Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer. Hepatology 60 (3), pp. 884 - 895 (2014)
81.
Journal Article
Piazza, I.; Rutkowska, A.; Ori, A.; Walczak, M.; Metz, J.; Pelechano, V.; Beck, M.; Haering, C. H.: Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. Nature Structural and Molecular Biology 21 (6), pp. 560 - 568 (2014)
82.
Journal Article
Beck, M.; Glavy, J. S.: Toward understanding the structure of the vertebrate nuclear pore complex. The Nucleus 5 (2), pp. 119 - 123 (2014)
83.
Journal Article
Bui, K. H.; von Appen, A.; DiGuilio, A. L.; Ori, A.; Sparks, L.; Mackmull, M.-T.; Bock, T.; Hagen, W.; Andrés-Pons, A.; Glavy, J. S. et al.; Beck, M.: Integrated structural analysis of the human nuclear pore complex scaffold. Cell 155 (6), pp. 1233 - 1243 (2013)
84.
Journal Article
Thierbach, K.; von Appen, A.; Thoms, M.; Beck, M.; Flemming, D.; Hurt, E.: Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy. Structure 21 (9), pp. 1672 - 1682 (2013)
85.
Journal Article
Banterle, N.; Bui, K. H.; Lemke, E. A.; Beck, M.: Fourier ring correlation as a resolution criterion for super-resolution microscopy. Journal of Structural Biology 183 (3), pp. 363 - 367 (2013)
86.
Journal Article
Milles, S.; Huy Bui, K.; Koehler, C.; Eltsov, M.; Beck, M.; Lemke, E. A.: Facilitated aggregation of FG nucleoporins under molecular crowding conditions. EMBO Reports 14 (2), pp. 178 - 183 (2013)
87.
Journal Article
Ori, A.; Banterle, N.; Iskar, M.; Andrés-Pons, A.; Escher, C.; Khanh Bui, H.; Sparks, L.; Solis-Mezarino, V.; Rinner, O.; Bork, P. et al.; Lemke, E. A.; Beck, M.: Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology 9, 648 (2013)
88.
Journal Article
Herzog, F.; Kahraman, A.; Boehringer, D.; Mak, R.; Bracher, A.; Walzthoeni, T.; Leitner, A.; Beck, M.; Hartl, F.-U.; Ban, N. et al.; Malmström, L.; Aebersold, R.: Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry. Science 337 (6100), pp. 1348 - 1352 (2012)
89.
Journal Article
Walzthoeni, T.; Claassen, M.; Leitner, A.; Herzog, F.; Bohn, S.; Förster, F.; Beck, M.; Aebersold, R.: False discovery rate estimation for cross-linked peptides identified by mass spectrometry. Nature Methods 9 (9), pp. 901 - 903 (2012)
90.
Journal Article
Xu, M.; Beck, M.; Alber, F.: High-throughput subtomogram alignment and classification by Fourier space constrained fast volumetric matching. Journal of Structural Biology 178 (2), pp. 152 - 164 (2012)
91.
Journal Article
Beck, M.; Schmidt, A.; Malmstroem, J.; Claassen, M.; Ori, A.; Szymborska, A.; Herzog, F.; Rinner, O.; Ellenberg, J.; Aebersold, R.: The quantitative proteome of a human cell line. Molecular Systems Biology 7, 549 (2011)
92.
Journal Article
Schmidt, A.; Beck, M.; Malmström, J.; Lam, H.; Claassen, M.; Campbell, D.; Aebersold, R.: Absolute quantification of microbial proteomes at different states by directed mass spectrometry. Molecular Systems Biology 7, 510 (2011)
93.
Journal Article
Reiter, L.; Rinner, O.; Picotti, P.; Hüttenhain, R.; Beck, M.; Brusniak, M.-Y.; Hengartner, M. O.; Aebersold, R.: mProphet: automated data processing and statistical validation for large-scale SRM experiments. Nature Methods 8 (5), pp. 430 - 435 (2011)
94.
Journal Article
Beck, M.; Topf, M.; Frazier, Z.; Tjong, H.; Xu, M.; Zhang, S.; Alber, F.: Exploring the spatial and temporal organization of a cell's proteome. Journal of Structural Biology 173 (3), pp. 483 - 496 (2011)
95.
Journal Article
Beck, M.; Claassen, M.; Aebersold, R.: Comprehensive proteomics. Current Opinion in Biotechnology 22 (1), pp. 3 - 8 (2011)
96.
Journal Article
Xu, M.; Beck, M.; Alber, F.: Template-free detection of macromolecular complexes in cryo electron tomograms. Bioinformatics 27 (13), pp. i69 - i76 (2011)
97.
Journal Article
Bohn, S.; Beck, F.; Sakata, E.; Walzthoeni, T.; Beck, M.; Aebersold, R.; Förster, F.; Baumeister, W.; Nickell, S.: Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proceedings of the National Academy of Sciences of the United States of America 107 (49), pp. 20992 - 20997 (2010)
98.
Journal Article
Leitner, A.; Walzthoeni, T.; Kahraman, A.; Herzog, F.; Rinner, O.; Beck, M.; Aebersold, R.: Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics. Molecular and Cellular Proteomics 9 (8), pp. 1634 - 1649 (2010)
99.
Journal Article
Beck, M.; Malmström, J. A.; Lange, V.; Schmidt, A.; Deutsch, E. W.; Aebersold, R.: Visual proteomics of the human pathogen Leptospira interrogans. Nature Methods 6 (11), pp. 817 - 823 (2009)
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