Journal Article (3097)
2021
Journal Article
24 (12), e103524 (2021)
Closantel is an allosteric inhibitor of human Taspase1. iScience
Journal Article
118 (50), e2114013118 (2021)
Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
57 (96), pp. 12948 - 12951 (2021)
Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications
Journal Article
11 (1), e23852 (2021)
Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases. Scientific Reports
Journal Article
374 (6573), eabd9776 (2021)
Nuclear pores dilate and constrict in cellulo. Science
Journal Article
12 (1), 6982 (2021)
Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases. Nature Communications
Journal Article
12, 6903 (2021)
Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications
Journal Article
81, pp. 4635 - 4649 (2021)
Structural basis of polyamine transport by human ATP13A2 (PARK9). Molecular Cell
Journal Article
22 (22), pp. 3172 - 3177 (2021)
Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem
Journal Article
118 (46), e2107335118 (2021)
The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
7 (46), eabj3221 (2021)
High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances
Journal Article
7 (46), eabj5255 (2021)
Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances
Journal Article
22 (11), e52476 (2021)
A phosphatase-centric mechanism drives stress signaling response. EMBO Reports
Journal Article
595 (21), pp. 2701 - 2714 (2021)
Cardiolipin prevents pore formation in phosphatidylglycerol bacterial membrane models. FEBS Letters
Journal Article
Sample Preparation by 3D-Correlative Focused Ion Beam Milling for High-Resolution Cryo-Electron Tomography. Journal of Visualized Experiments (176), e62886 (2021)
Journal Article
12 (1), 6127 (2021)
Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins. Nature Communications
Journal Article
1 (12), pp. 2162 - 2171 (2021)
Solution Structure and Conformational Flexibility of a Polyketide Synthase Module. JACS Au
Journal Article
121 (19), pp. 11701 - 11725 (2021)
Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems. Chemical Reviews
Journal Article
12 (1), 5934 (2021)
Simultaneous orientation and 3D localization microscopy with a Vortex point spread function. Nature Communications
Journal Article
60 (42), pp. 23010 - 23017 (2021)
The voltage dependent sidedness of the reprotonation of the retinal Schiff base determines the unique inward pumping of Xenorhodopsin. Angewandte Chemie, International Edition in English
Journal Article
186, 105905 (2021)
Expression, purification and characterization of the IcmG and IcmK proteins of the Type IVB secretion system from Coxiella burnetii. Protein Expression and Purification
Journal Article
118 (37), e2113647118 (2021)
p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
12 (1), 5364 (2021)
In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications
Journal Article
22 (9), e52289 (2021)
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. EMBO Reports
Journal Article
373 (6559), pp. 1151 - 1156 (2021)
Three-megadalton complex of methanogenic electron-bifurcating and CO2-fixing enzymes. Science
Journal Article
12 (1), 5236 (2021)
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications
Journal Article
6 (9), pp. 1129 - 1139 (2021)
Structural and functional characterization of the intracellular filament-forming nitrite oxidoreductase multiprotein complex. Nature Microbiology
Journal Article
155 (8), 084503 (2021)
Kinetic pathways of water exchange in the first hydration shell of magnesium: Influence of water model and ionic force field. The Journal of Chemical Physics
Journal Article
36 (8), 109583 (2021)
Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling. Cell Reports
Journal Article
32 (17), pp. 1523 - 1533 (2021)
Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex. Molecular Biology of the Cell
Journal Article
220 (8), e202011078 (2021)
Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1. The Journal of Cell Biology
Journal Article
297 (2), 100925 (2021)
Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. The Journal of Biological Chemistry
Journal Article
1862 (8), e148436 (2021)
Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
9 (8), 1636 (2021)
Polyhydroxyalkanoate (PHA) Production in Pseudomonas sp. phDV1 Strain Grown on Phenol as Carbon Sources. Microorganisms
Journal Article
DEER Spectroscopy of Channelrhodopsin-2 Helix B Movements in Trapped Photocycle Intermediates. Applied Magnetic Resonance (2021)
Journal Article
125 (28), pp. 7732 - 7741 (2021)
Binding of SARS-CoV-2 Fusion Peptide to Host Endosome and Plasma Membrane. The Journal of Physical Chemistry B
Journal Article
60 (30), pp. 16442 - 16447 (2021)
The Desensitized Channelrhodopsin-2 Photointermediate Contains 13 -cis, 15 -syn Retinal Schiff Base. Angewandte Chemie, International Edition in English
Journal Article
16 (7), e0253364 (2021)
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One
Journal Article
28 (7), pp. 1014 - 1031 (2021)
Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation. Cell Chemical Biology
Journal Article
11 (1), 13657 (2021)
A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments. Scientific Reports
Journal Article
4 (1), 821 (2021)
Structure-based insights into evolution of rhodopsins. Communications Biology
Journal Article
10, e70160 (2021)
Structure and mechanistic features of the prokaryotic minimal RNase P. eLife
Journal Article
154 (23), 234105 (2021)
Maximum likelihood estimates of diffusion coefficients from single-particle tracking experiments. The Journal of Chemical Physics
Journal Article
60 (24), pp. 13323 - 13330 (2021)
The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English
Journal Article
7 (23), eabg0465 (2021)
Structure of the merozoite surface protein 1 from Plasmodium falciparum. Science Advances
Journal Article
33 (6), pp. 2072 - 2091 (2021)
A ferredoxin bridge connects the two arms of plant mitochondrial complex I. The Plant Cell
Journal Article
118 (19), e2100425118 (2021)
Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
118 (19), e2016974118 (2021)
Membrane fusion and drug delivery with carbon nanotube porins. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
154 (17), 171102 (2021)
Extended magnesium and calcium force field parameters for accurate ion–nucleic acid interactions in biomolecular simulations. The Journal of Chemical Physics
Journal Article
16 (4), e0239881 (2021)
Refining pairwise sequence alignments of membrane proteins by the incorporation of anchors. plos one
Journal Article
7 (4), pp. 514 - 523 (2021)
Molecular landscape of etioplast inner membranes in higher plants. Nature Plants
Journal Article
701, 108796 (2021)
Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics
Journal Article
17 (4), pp. 2530 - 2540 (2021)
Optimized Magnesium Force Field Parameters for Biomolecular Simulations with Accurate Solvation, Ion-Binding, and Water-Exchange Properties. Journal of Chemical Theory and Computation
Journal Article
9, 680533 (2021)
Editorial: Integrating Timescales From Molecules Up. Frontiers in Chemistry
Journal Article
7, pp. 524 - 538 (2021)
Structural insights into photosystem II assembly. Nature Plants
Journal Article
1862 (4), 148379 (2021)
Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
595 (7), pp. 864 - 880 (2021)
The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways. FEBS Letters
Journal Article
17 (4), e1008790 (2021)
Computational epitope map of SARS-CoV-2 spike protein. PLoS Computational Biology
Journal Article
8, 636562 (2021)
Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders. Frontiers in Molecular Biosciences
Journal Article
26 (6), 1664 (2021)
PepFun: Open Source Protocols for Peptide-Related Computational Analysis. Molecules
Journal Article
7 (11), eabf4213 (2021)
Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-enhanced solid-state NMR. Science Advances
Journal Article
54, e4 (2021)
Current limitations to high-resolution structure determination by single-particle cryoEM. Quarterly Reviews of Biophysics
Journal Article
213 (1), 107701 (2021)
Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography. Journal of Structural Biology
Journal Article
288 (5), pp. 1664 - 1678 (2021)
Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal
Journal Article
8 (Pt 2), pp. 186 - 194 (2021)
Devitrification reduces beam-induced movement in cryo-EM. IUCrJ
Journal Article
12 (7), pp. 1926 - 1931 (2021)
FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes. The Journal of Physical Chemistry Letters
Journal Article
24 (2), 102021 (2021)
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening. iScience
Journal Article
184 (4), pp. 1032 - 1046 (2021)
Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell
Journal Article
12 (1), 1074 (2021)
Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers. Nature Communications
Journal Article
120 (3), pp. 568 - 575 (2021)
Temperature Dependence of the Krokinobacter rhodopsin 2 Kinetics. Biophysical Journal (Annual Meeting Abstracts)
Journal Article
12, pp. 93 - 101 (2021)
Fusion of purple membranes triggered by immobilization on carbon nanomembranes. Beilstein Journal of Nanotechnology
Journal Article
17 (1), pp. 525 - 537 (2021)
Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model. Journal of Chemical Theory and Computation
Journal Article
11 (1), 618 (2021)
Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Scientific Reports
Journal Article
12 (1), 230 (2021)
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution. Nature Communications
Journal Article
54, e2 (2021)
Setting up and operating a cryo-EM laboratory. Quarterly Reviews of Biophysics
Journal Article
20, 100016 (2021)
Proteome Turnover in the Spotlight: Approaches, Applications, and Perspectives. Molecular and Cellular Proteomics
Journal Article
28 (1), pp. 2 - 7 (2021)
Structural biology in the fight against COVID-19. Nature Structural and Molecular Biology
Journal Article
17 (1), pp. 1 - 382 (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy
Journal Article
21 (2), e2000003 (2021)
Proteomic Characterization of the Pseudomonas sp. Strain phDV1 Response to Monocyclic Aromatic Compounds. Proteomics
Journal Article
22 (2), 566 (2021)
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. International Journal of Molecular Sciences 2020
Journal Article
21 (1), 586 (2020)
An automated protocol for modelling peptide substrates to proteases. BMC Bioinformatics
Journal Article
117 (50), pp. 31838 - 31849 (2020)
A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
59, pp. 23025 - 23029 (2020)
Compaction of RNA duplexes in the cell. Angewandte Chemie, International Edition in English
Journal Article
29, pp. 2398 - 2407 (2020)
Consensus mutagenesis approach improves the thermal stability of system xc- transporter, xCT, and enables cryo-EM analyses. Protein Science
Journal Article
65 (7), pp. 1226 - 1230 (2020)
Purification and Preliminary X-Ray Crystallographic Analysis of the Peptidyl-Prolyl cis-trans Isomerase Alr5059 from Anabaena sp. PCC 7120. Crystallography Reports
Journal Article
11, 6008 (2020)
Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I. Nature Communications
Journal Article
587 (7835), pp. 657 - 662 (2020)
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature
Journal Article
9 (2020)
Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection. eLife
Journal Article
11, 5707 (2020)
Viral rhodopsins 1 are an unique family of light-gated cation channels. Nature Communications
Journal Article
594, pp. 3776 - 3789 (2020)
Cryo-EM of ABC transporters: an ice-cold solution to everything? FEBS Letters
Journal Article
11 (1), 5569 (2020)
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nature Communications
Journal Article
117 (44), pp. 27132 - 27140 (2020)
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
594 (21), pp. 3551 - 3567 (2020)
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution. FEBS Letters
Journal Article
175, 105689 (2020)
LptC from Anabaena sp. PCC 7120: Expression, purification and crystallization. Protein Expression and Purification
Journal Article
586 (7831), pp. 796 - 800 (2020)
In-cell architecture of the nuclear pore and snapshots of its turnover. Nature
Journal Article
11, 593467 (2020)
Exploring Bacterial Microcompartments in the Acetogenic Bacterium Acetobacterium woodii. Frontiers in Microbiology
Journal Article
370 (6513), pp. 203 - 208 (2020)
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science
Journal Article
16 (10), pp. 1078 - 1086 (2020)
p63 uses a switch-like mechanism to set the threshold for induction of apoptosis. Nature Chemical Biology
Journal Article
153 (14), 144105 (2020)
MDBenchmark: A toolkit to optimize the performance of molecular dynamics simulations. The Journal of Chemical Physics