
Publications of the Max Planck Institute of Biophysics
Journal Article (76)
2020
Journal Article
21 (1), 586 (2020)
An automated protocol for modelling peptide substrates to proteases. BMC Bioinformatics
Journal Article
117 (50), pp. 31838 - 31849 (2020)
A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
59, pp. 23025 - 23029 (2020)
Compaction of RNA duplexes in the cell. Angewandte Chemie, International Edition in English
Journal Article
29, pp. 2398 - 2407 (2020)
Consensus mutagenesis approach improves the thermal stability of system xc- transporter, xCT, and enables cryo-EM analyses. Protein Science
Journal Article
65 (7), pp. 1226 - 1230 (2020)
Purification and Preliminary X-Ray Crystallographic Analysis of the Peptidyl-Prolyl cis-trans Isomerase Alr5059 from Anabaena sp. PCC 7120. Crystallography Reports
Journal Article
11, 6008 (2020)
Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I. Nature Communications
Journal Article
587 (7835), pp. 657 - 662 (2020)
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature
Journal Article
9 (2020)
Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection. eLife
Journal Article
11, 5707 (2020)
Viral rhodopsins 1 are an unique family of light-gated cation channels. Nature Communications
Journal Article
594, pp. 3776 - 3789 (2020)
Cryo-EM of ABC transporters: an ice-cold solution to everything? FEBS Letters
Journal Article
11 (1), 5569 (2020)
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nature Communications
Journal Article
117 (44), pp. 27132 - 27140 (2020)
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
594 (21), pp. 3551 - 3567 (2020)
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution. FEBS Letters
Journal Article
175, 105689 (2020)
LptC from Anabaena sp. PCC 7120: Expression, purification and crystallization. Protein Expression and Purification
Journal Article
586 (7831), pp. 796 - 800 (2020)
In-cell architecture of the nuclear pore and snapshots of its turnover. Nature
Journal Article
11, 593467 (2020)
Exploring Bacterial Microcompartments in the Acetogenic Bacterium Acetobacterium woodii. Frontiers in Microbiology
Journal Article
370 (6513), pp. 203 - 208 (2020)
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science
Journal Article
16 (10), pp. 1078 - 1086 (2020)
p63 uses a switch-like mechanism to set the threshold for induction of apoptosis. Nature Chemical Biology
Journal Article
153 (14), 144105 (2020)
MDBenchmark: A toolkit to optimize the performance of molecular dynamics simulations. The Journal of Chemical Physics
Journal Article
26 (6), pp. 615 - 617 (2020)
Neue Möglichkeiten für die Strukturbestimmung von Membranproteinen. Biospektrum
Journal Article
34 (10), pp. 1063 - 1077 (2020)
Flexi-pharma: a molecule-ranking strategy for virtual screening using pharmacophores from ligand-free conformational ensembles. Journal of Computer-Aided Molecular Design
Journal Article
26, p. 650 - 650 (2020)
Kryo-EM-Einzelpartikelanalyse eines Membrantransporters in Liposomen. Biospektrum
Journal Article
94 (20), e01664-19 (2020)
Structure of Merkel cell polyomavirus capsid and interaction with its glycosaminoglycan attachment receptor. Journal of Virology
Journal Article
10, 557027 (2020)
In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes. Frontiers in Cellular and Infection Microbiology
Journal Article
15 (9), pp. 2956 - 2979 (2020)
Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. Nature Protocols
Journal Article
119, pp. 939 - 949 (2020)
Mechanical Unfolding of Proteins - A Comparative Nonequilibrium Molecular Dynamics Study. Biophysical Journal
Journal Article
369 (6508), eaaz7714 (2020)
Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation. Science
Journal Article
74, pp. 713 - 733 (2020)
Structural Basis of Hydrogenotrophic Methanogenesis. Annual Review of Microbiology
Journal Article
117 (35), 202008111, pp. 21281 - 21287 (2020)
Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
117 (34), pp. 20920 - 20925 (2020)
Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
14 (8), pp. 9972 - 9978 (2020)
Smart Molecular Nanosheets for Advanced Preparation of Biological Samples in Electron Cryo-Microscopy. ACS Nano
Journal Article
16 (8), e1007898 (2020)
In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target. PLoS Computational Biology
Journal Article
27 (8), pp. 743 - 751 (2020)
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nature Structural and Molecular Biology
Journal Article
63 (2020)
Respiratory complex I - structure, mechanism and evolution. Current Opinion in Structural Biology
Journal Article
117 (8), 083701 (2020)
Electron beam-induced electrostatic charging causes spectral changes of an insulating electrochromic material. Applied Physics Letters
Journal Article
11, 3709 (2020)
Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM. Nature Communications
Journal Article
4, 100032 (2020)
Validation tests for cryo-EM maps using an independent particle set. Journal of Structural Biology: X
Journal Article
15 (14), pp. 1262 - 1271 (2020)
Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo3 Ubiquinol Oxidase from Escherichia coli. ChemMedChem
Journal Article
153 (2), 024116 (2020)
Optimal estimates of self-diffusion coefficients from molecular dynamics simulations. The Journal of Chemical Physics
Journal Article
153 (2), 021101 (2020)
Systematic errors in diffusion coefficients from long-time molecular dynamics simulations at constant pressure. The Journal of Chemical Physics
Journal Article
11 (3), e02615-19 (2020)
Isolated Heme A Synthase from Aquifex aeolicus Is a Trimer. mBio
Journal Article
14 (7), pp. 8181 - 8190 (2020)
Assembling Carbon Nanotube Architectures. ACS Nano
Journal Article
152 (22), 224106 (2020)
Kinetic pathways of water exchange in the first hydration shell of magnesium. The Journal of Chemical Physics
Journal Article
124 (23), pp. 4673 - 4685 (2020)
Quantifying Protein-Protein Interactions in Molecular Simulations. The Journal of Physical Chemistry B
Journal Article
36 (21), pp. 5979 - 5989 (2020)
Hofmeister Series for Metal-Cation-RNA Interactions: The Interplay of Binding Affinity and Exchange Kinetics. Langmuir
Journal Article
26 (6), p. 650 - 650 (2020)
Kryo-EM-Einzelpartikelanalyse eines Membrantransporters in Liposomen. Biospektrum
Journal Article
60 (5), pp. 2413 - 2418 (2020)
Need for Cross-Validation of Single Particle Cryo-EM. Journal of Chemical Information and Modeling
Journal Article
11, 2231 (2020)
Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium. Nature Communications
Journal Article
401 (6-7), pp. 687 - 697 (2020)
The structure of the TOM core complex in the mitochondrial outer membrane. Biological Chemistry
Journal Article
85 (5), pp. 545 - 552 (2020)
In vitro Reconstitution of the S. aureus 30S Ribosomal Subunit and RbfA Factor Complex for Structural Studies. Biochemistry-Moscow
Journal Article
11, 2137 (2020)
Molecular mechanism of light-driven sodium pumping. Nature Communications
Journal Article
368 (6489), eaaz2449, p. 385 (2020)
Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science
Journal Article
142 (16), pp. 7647 - 7654 (2020)
Site-Specific Detection of Arginine Methylation in Highly Repetitive Protein Motifs of Low Sequence Complexity by NMR. Journal of the American Chemical Society
Journal Article
9, e52939 (2020)
Proteome dynamics during homeostatic scaling in cultured neurons. eLife
Journal Article
11, 480 (2020)
Molecular and Low-Resolution Structural Characterization of the Na+-Translocating Glutaconyl-CoA Decarboxylase From Clostridium symbiosum. Frontiers in Microbiology
Journal Article
432 (7), pp. 2042 - 2054 (2020)
The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. Journal of Molecular Biology (London)
Journal Article
117 (10), pp. 5109 - 5110 (2020)
Reply to Desikan et al.: Micelle formation among various mechanisms of toxin pore formation. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
21 (5), e49891 (2020)
Structure of RyR1 in native membranes. EMBO Reports
Journal Article
27 (3), pp. 833 - 842 (2020)
ER-phagy and human diseases. Cell Death and Differentiation
Journal Article
117 (8), pp. 4131 - 4141 (2020)
High-resolution structural insights into the heliorhodopsin family. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
4 (2), pp. 213 - 221 (2020)
Methanogenesis involves direct hydride transfer from H2 to an organic substrate. Nature Reviews Chemistry
Journal Article
11, 876 (2020)
Benchmarking tomographic acquisition schemes for high-resolution structural biology. Nature Communications
Journal Article
11, 756 (2020)
Regulation of lipid saturation without sensing membrane fluidity. Nature Communications
Journal Article
92 (5), pp. 4016 - 4022 (2020)
Proteome-Wide Structural Probing of Low-Abundant Protein Interactions by Cross-Linking Mass Spectrometry. Analytical Chemistry
Journal Article
22 (2), pp. 159 - 166 (2020)
Selective autophagy degrades nuclear pore complexes. Nature Cell Biology
Journal Article
367 (6477), eaay4991, p. 526 (2020)
Monosomes actively translate synaptic mRNAs in neuronal processes. Science
Journal Article
11, 626 (2020)
Structural basis of proton-coupled potassium transport in the KUP family. Nature Communications
Journal Article
7 (Pt 2), pp. 220 - 227 (2020)
The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase. IUCrJ
Journal Article
48 (2), pp. 924 - 933 (2020)
High-resolution EPR distance measurements on RNA and DNA with the non-covalent Ǵ spin label. Nucleic Acids Research
Journal Article
48 (2), pp. 934 - 948 (2020)
Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif. Nucleic Acids Research (London)
Journal Article
10 (1), 895 (2020)
Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS). Scientific Reports
Journal Article
124 (2), pp. 336 - 344 (2020)
Ion Binding and Selectivity of the Na+/H+ Antiporter MjNhaP1 from Experiment and Simulation. The Journal of Physical Chemistry B
Journal Article
16 (1), pp. 725 - 737 (2020)
Hierarchical Ensembles of Intrinsically Disordered Proteins at Atomic Resolution in Molecular Dynamics Simulations. Journal of Chemical Theory and Computation
Journal Article
77 (1), pp. 164 - 179 (2020)
Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Molecular Cell
Journal Article
59 (1), pp. 343 - 351 (2020)
A 3.3 Å‐Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of its Thermal Stability. Angewandte Chemie, International Edition in English
Journal Article
26 (7), p. 750 (2020)
Klassifizierung von Antikörpern zur Behandlung von COVID-19. Biospektrum Conference Paper (2)
2020
Conference Paper
118 (3), Supplement 1 Ed., p. 359A (2020)
Computational Design of Peptides Bound to the Major Histocompatibility Complex Class II. 64th Annual Meeting of the Biophysical-Society, San Diego, CA, February 15, 2020 - February 19, 2020. Biophysical Journal
Conference Paper
11246, UNSP 112460N (Eds. Gregor, I.; Koberling, F.; Erdmann, R.). SPIE BIOS, San Francisco, Carlifornia, United States, February 01, 2020 - February 02, 2020. Spie-Int Soc Optical Engineering, Bellingham (2020)
Quantitative single-molecule localization microscopy reports on protein numbers in signaling protein complexes. In: Proceedings of SPIE: Single molecule spectroscopy and superresolution imaging XIII, Vol. Thesis - PhD (7)
2020
Thesis - PhD
Cryo electron microscopy study on gating mechanism of the lipid-modulated serotonin receptor. Dissertation, 192 pp., Fachbereich Biochemie, Chemie und Pharmzie der Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Structure and function of integral and peripheral membrane proteins by cryo-EM: RyR1 and SidE family proteins. Dissertation, 118 pp., Fachbereich Biochemie, Chemie und Pharmazie der Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Single-Particle Electron Microscopy of Mitochondrial Protein Import. Dissertation, 183 pp., Fachbereich Biowissenschaften, Goethe Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Structural and functional characterization of cytochrome c oxidase, cytochrome bc1 complex and heme A synthase from Aquifex aeolicus. Dissertation, 171 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Structural Investigation of Membrane Proteins by Hydrogen/Deuterium Exchange Mass Spectrometry. Dissertation, 185 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Methods for Simulation and Calculation of Diffusion. Dissertation, 162 pp., Fachbereich Physik, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2020)
Thesis - PhD
Protein turnover in neurons and its regulation during homeostatic synaptic scaling. Dissertation, 169 pp., Fachbereich Biowissenschaften der Johann Wolfgang Goethe-Universität, Frankfurt am Main (2020)
Thesis - Master (3)
2020
Thesis - Master
Structural characterization of membrane-integrated enzyme complexes. Master, 49 pp., Institute für Organische Chemie und Chemische Biologie, Goethe-Universität Frankfurt, Frankfurt am Main (2020)
Thesis - Master
Recombinant expression and characterization of Anabaena sp. ABC transporter-driven tripartite efflux pumps. Master, 114 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe-Universität, Frankfurt am Main (2020)
Thesis - Master
Development of an automated pipeline for 3D-classification based particle picking in Cryo-EM using Python. Master, 91 pp., Goethe-Universität, Frankfurt am Main (2020)
Thesis - Bachelor (2)
2020
Thesis - Bachelor
Rapid Nanobody Discovery for Purification of Membrane Protein Complexes. Bachelor, 46 pp., Department of Physics, Johann Wolfgang Goethe-University Frankfurt, Frankfurt am Main (2020)
Thesis - Bachelor
Ermittlung eines Nanobodys zur Affinitäts-Aufreinigung von Ndh-1 aus Erbse. Bachelor, 84 pp., Fakultät Life Sciences, Hochschule Rhein-Waal, Kleve (2020)
Editorial (1)
2020
Editorial
26 (11), p. 703 - 703 (2020)
25 Jahre BIOspektrum: mit Meilensteinen der Forschung in die Zukunft. Biospektrum